Prediction of oral drug absorption in humans by theoretical passive absorption model

International Journal of Pharmaceutics

Volumn 293, Issue 1-2, 2005, Pages 183-192

  Obata, Kouki ^a   Sugano, Kiyohiko ^a,b   Saitoh, Ryoichi ^a   Higashida, Atsuko ^a   Nabuchi, Yoshiaki ^a   Machida, Minoru ^a   Aso, Yosinori ^a  

^a CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^b PFIZER INC   (United States)

Author keywords

In silico; Lipophilicity; Octanol; Oral absorption; Permeability; pKa

Indexed keywords

ACICLOVIR; AMILORIDE; ATENOLOL; BUFFER; CARBAMAZEPINE; CATION; CEFTRIAXONE; CEFUROXIME; CIMETIDINE; CREATININE; DESIPRAMINE; FLUINDOSTATIN; FUROSEMIDE; HYDROCHLOROTHIAZIDE; KETOPROFEN; METOPROLOL; NAPROXEN; OCTANOL; OXACILLIN; PHENAZONE; PIROXICAM; PROPRANOLOL; RANITIDINE; TERBUTALINE; TIMOLOL; WATER;

ARTICLE; CHEMICAL STRUCTURE; CHROMATOGRAPHY; CORRELATION COEFFICIENT; DIFFUSION; DRUG ABSORPTION; DRUG RESEARCH; DRUG USE; ELECTRICITY; HUMAN; HYPOTHESIS; INTESTINE MUCOSA PERMEABILITY; MATHEMATICAL ANALYSIS; MOLECULAR WEIGHT; PH; PRIORITY JOURNAL;

EID: 15244345072     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2005.01.005     Document Type: Article

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