Review of theoretical passive drug absorption models: Historical background, recent developments and limitations

Pharmaceutica Acta Helvetiae

Volumn 71, Issue 5, 1996, Pages 309-327

  Camenisch, Gian ^a,b   Folkers, Gerd ^b   Van De Waterbeemd, Han ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b ETH ZURICH   (Switzerland)

Author keywords

Absorption models; Distribution; Distribution models; Drug absorption; Drug transport; Lipophilicity; Membrane permeation; Pore diffusion

Indexed keywords

BLOOD BRAIN BARRIER; DIFFUSION COEFFICIENT; DRUG ABSORPTION; DRUG TRANSPORT; HISTORY; LIPOPHILICITY; MATHEMATICAL MODEL; MEMBRANE PERMEABILITY; MEMBRANE TRANSPORT; PARTITION COEFFICIENT; REVIEW; THEORY;

ABSORPTION; CELL MEMBRANE PERMEABILITY; CHEMISTRY, PHYSICAL; MATHEMATICAL COMPUTING; MODELS, BIOLOGICAL; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS;

EID: 0030296370     PISSN: 00316865     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-6865(96)00031-3     Document Type: Review

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