Correlation of human jejunal permeability (in vivo) of drugs with experimentally and theoretically derived parameters. A multivariate data analysis approach

Journal of Medicinal Chemistry

Volumn 41, Issue 25, 1998, Pages 4939-4949

  Winiwarter, Susanne ^a   Bonham, Nicholas M ^a   Ax, Fredrik ^a   Hallberg, Anders ^a   Lennernäs, Hans ^a   Karlén, Anders ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; ATENOLOL; CARBAMAZEPINE; CREATININE; DESIPRAMINE; DRUG; ENALAPRILAT; FLUINDOSTATIN; FUROSEMIDE; GLUCOSE; HYDROCHLOROTHIAZIDE; KETOPROFEN; LEUCINE; LEVODOPA; METHYLDOPA; METOPROLOL; NAPROXEN; OCTANOL; PHENAZONE; PIROXICAM; PROPRANOLOL; TERBUTALINE; UREA; VERAPAMIL; WATER;

ARTICLE; CONTROLLED DRUG RELEASE; DRUG ABSORPTION; DRUG DIFFUSION; DRUG PENETRATION; HUMAN; INTESTINE MUCOSA PERMEABILITY; INTESTINE PERFUSION; JEJUNUM; LIPOPHILICITY; MULTIVARIATE ANALYSIS; ORAL DRUG ADMINISTRATION; PARTITION COEFFICIENT; PH MEASUREMENT; PHYSICAL CHEMISTRY; PKA; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

HUMANS; INTESTINAL ABSORPTION; JEJUNUM; MODELS, BIOLOGICAL; MULTIVARIATE ANALYSIS; PERMEABILITY; PHARMACEUTICAL PREPARATIONS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032480901     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9810102     Document Type: Article

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