Correlating partitioning and Caco-2 cell permeability of structurally diverse small molecular weight compounds

Pharmaceutical Research

Volumn 15, Issue 9, 1998, Pages 1490-1494

  Yazdanian, Mehran ^a   Glynn, Susan L ^a   Wright, James L ^a   Hawi, Amale ^a  

^a BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

Author keywords

Caco 2 cells; Hexadecane; Octanol; Partitioning; Permeability; Propyleneglycol dipelargonate

Indexed keywords

ARTICLE; CELL MEMBRANE PERMEABILITY; CELL STRAIN CACO 2; CELL TRANSPORT; HUMAN; HUMAN CELL; MEMBRANE MODEL; MEMBRANE STRUCTURE; MOLECULAR WEIGHT; PARTITION COEFFICIENT; PRIORITY JOURNAL;

ALKANES; CACO-2 CELLS; CELL MEMBRANE PERMEABILITY; ESTERS; HUMANS; HYDROGEN BONDING; MOLECULAR WEIGHT; OCTANOLS; PHARMACOKINETICS; PROPYLENE GLYCOLS; SOLVENTS;

EID: 0031781430     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011930411574     Document Type: Article

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