Evaluation of a vincristine resistant Caco-2 cell line for use in a calcein AM extrusion screening assay for P-glycoprotein interaction

European Journal of Pharmaceutical Sciences

Volumn 12, Issue 3, 2001, Pages 205-214

  Eneroth, A ^a   Astrom E ^a   Hoogstraate, J ^a   Schrenk, D ^b   Conrad, S ^b   Kauffmann, H M ^b   Gjellan, K ^a  

^a ASTRAZENECA R AND D   (Sweden)

^b Rheinland Pfälzische Technische Universität Kaiserslautern Landau   (Germany)

Author keywords

Caco 2 cells; Calcein AM; P Glycoprotein; Vincristine sulfate

Indexed keywords

CALCEIN; CHLORPROMAZINE; CYCLOSPORIN A; DIGOXIN; DOMPERIDONE; GLYCOPROTEIN P; ISOPROTEIN; IVERMECTIN; KETOCONAZOLE; LOPERAMIDE; MESSENGER RNA; METOPROLOL; MULTIDRUG RESISTANCE PROTEIN; ONCOVINE; PROGESTERONE; PROPRANOLOL; QUINIDINE; QUININE; VERAPAMIL; VINCRISTINE SULFATE;

ANALYTIC METHOD; ARTICLE; CELL LEVEL; CELL STRAIN CACO 2; CONTROLLED STUDY; DRUG EXPOSURE; DRUG SCREENING; DRUG TRANSPORT; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; VALIDATION PROCESS;

EID: 0033669380     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-0987(00)00117-2     Document Type: Article

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