HT29-MTX/Caco-2 cocultures as an in vitro model for the intestinal epithelium: In vitro-in vivo correlation with permeability data from rats and humans

Journal of Pharmaceutical Sciences

Volumn 85, Issue 10, 1996, Pages 1070-1076

  Walter, Elke ^a   Janich, Sonia ^b   Roessler, Blake J ^b   Hilfinger, John M ^c   Amidon, Gordon L ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c TSRL INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; AMPICILLIN; ATENOLOL; CEFALEXIN; CIMETIDINE; FUROSEMIDE; LEVODOPA; METHYLDOPA; NAPROXEN; PIROXICAM; PROPRANOLOL; RANITIDINE;

ANIMAL EXPERIMENT; ARTICLE; DRUG PENETRATION; DRUG TRANSPORT; GOBLET CELL; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; INTESTINE ABSORPTION; INTESTINE EPITHELIUM CELL; NONHUMAN; RAT; STOMACH MUCUS;

EID: 0029836840     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1021/js960110x     Document Type: Article

References (32)

1. Amidon, G. L.; Sinko, P. J.; Fleisher, D. Pharm. Res. 1988, 10, 651-654.
2. Artursson, P.; Karlsson, J. Biochem. Biophys. Res. Commun. 1991, 175, 880-885.
3. Amidon, G. L.; Lennernas, H.; Shah, V. P.; Crison, J. R. Pharm. Res. 1995, 12, 413-420.
4. Walter, E.; Kissel, T.; Reers, M.; Dickneite, G.; Hoffmann, D.; Stueber, W. Pharm. Res. 1995, 12, 360-365.
5. Stewart, B. H.; Chan, O. H.; Lu, R. H.; Reyner, E. L.; Schmid, H. L.; Hamilton, H. W.; Steinbaugh, B. A.; Taylor, M. D. Pharm. Res. 1995, 12, 693-699.
6. Rubas, W.; Jezyk, N.; Grass, G. M. Pharm. Res. 1993, 10, 113-118.
7. Walter, E.; Kissel, T. Pharm. Res. 1994, 11, 1575-1580.
8. Gan, L. S.; Hsyu, P. H.; Pritchard, J. F.; Thakker, D. Pharm. Res. 1993, 10, 1722-1725.
9. Hilgers, A. R.; Conradi, R. A.; Burton, P. S. Pharm. Res. 1990, 9, 902-910.
10. Artursson, P. J. Pharm. Sci. 1990, 79, 476-482.
11. Hidalgo, I. J.; Raub, T. J.; Borchardt, R. T. Gastroenterology 1989, 96, 736-749.
12. Artursson, P. Crit. Rev. Ther. Drug Carrier Syst. 1991, 8, 305-330.
13. Dix, C. J.; Hassan, I. F.; Obray, H. Y.; Shah, R.; Wilson, G. Gastroenterology 1990, 98, 1272-1279.
14. Bissonnette, P.; Biais, A.; Berteloot, A. Fed. Proc. 1987, 46, 1273.
15. Hu, M.; Borchardt, R. T. Biochim. Biophys. Acta 1992, 1135, 233-244.
16. Dantzig, A. H.; Bergin, L. Biochim. Biophys. Acta 1990, 1027, 211-217.
17. Lesuffleur, T.; Babat, A.; Luccioni, C.; Beaumatin, J.; Clair, M.; Kornowski, A.; Dussaulx, E.; Dutrillaux, B.; Zweibaum, A. J. Cell Biol. 1991, 115, 1409-1418.
18. Kerneis, S.; Bernet, M. F.; Coconnier, M. H.; Servin, A. L. Gut 1994, 35, 1449-1454.
19. Lesuffleur, T.; Barbat, A.; Dussaulx, E.; Zweibaum, A. Cancer Res. 1990, 50, 6334-6343.
20. Forstner, J. F.; Forstner, G. G. Gastrointestinal mucus. In Physiology of the gastrointestinal tract, 3rd ed.; Johnson, L. R., Ed.; Raven Press: New York, 1994; pp 1255-1283.
21. Johnson, L. R., Ed. Physiology of the gastrointestinal tract, 3rd ed.; Raven Press: New York, 1994.
22. Specian, R. D.; Oliver, M. G. Am. J. Physiol. 1991, 260, C183-C193
23. Artursson, P.; Ungell, A. L.; Löfroth, J. E. Pharm. Res. 1993, 10, 1123-1129.
24. Liang, R.; Fei, Y. J.; Prasad, P. D.; Ramamoorthy, S.; Han, H.; Yamg-Feng, T. L.; Hedinger, M. A.; Ganapathy, V.; Leibach, F. H. J. Biol. Chem. 1995, 270, 6456-6463.
25. Gochoco, C. H.; Ryan, F. M.; Miller, J.; Smith, P. L.; Hidalgo, I. J. Int. J. Pharm, 1994, 104, 187-202.
26. Dantzig, A. H.; Duckworth, D. C.; Tabas, L. B. Biochim. Biophys. Acta 1994, 1191, 7-13.
27. Dantzig, A. H.; Tabas, L. B.; Bergin, L. Biochim. Biophys. Acta 1992, 1112, 167-173.
28. Hu, M.; Chen, J.; Zhu, Y.; Dantzig, A. H.; Stratford, R. E.; Kuhfeld, M. T. Pharm. Res. 1994, 11, 1405-1413.
29. Amidon, G. L.; Lee, H. J. Annu. Rev. Pharmacol. Toxicol. 1994, 34, 321-341.
30. Oh, D. M.; Sinko, P. J.; Amidon, G. L. Pharm. Res. 1989, 6, S-91.
31. Amidon, G. L.; Merfeld, A. E.; Dressman, J. B. J. Pharm. Pharmacol. 1986, 38, 363-368.
32. Amidon, G. L., et al. Unpublished results.