-
1
-
-
0032900953
-
Biochemical, cellular, and pharmacological aspects of the multidrug transporter
-
S.V. Ambudkar, S. Dey, C.A. Hrycyna, M. Ramachandra, I. Pastan, and M.M. Gottesman Biochemical, cellular, and pharmacological aspects of the multidrug transporter Annu. Rev. Pharmacol. Toxicol. 39 1999 361 398
-
(1999)
Annu. Rev. Pharmacol. Toxicol.
, vol.39
, pp. 361-398
-
-
Ambudkar, S.V.1
Dey, S.2
Hrycyna, C.A.3
Ramachandra, M.4
Pastan, I.5
Gottesman, M.M.6
-
2
-
-
0037103569
-
Modulation of P-glycoprotein expression and function by curcumin in multidrug-resistant human KB cells
-
S. Anuchapreeda, P. Leechanachai, M.M. Smith, S.V. Ambudkar, and P.N. Limtrakul Modulation of P-glycoprotein expression and function by curcumin in multidrug-resistant human KB cells Biochem. Pharmacol. 64 2002 573 582
-
(2002)
Biochem. Pharmacol.
, vol.64
, pp. 573-582
-
-
Anuchapreeda, S.1
Leechanachai, P.2
Smith, M.M.3
Ambudkar, S.V.4
Limtrakul, P.N.5
-
3
-
-
0030922974
-
Multidrug resistance-reversing agents increase vinblastine distribution in normal tissues expressing the P-glycoprotein but do not enhance drug penetration in brain and testis
-
M. Arboix, O.G. Paz, T. Colombo, and M. D'Incalci Multidrug resistance-reversing agents increase vinblastine distribution in normal tissues expressing the P-glycoprotein but do not enhance drug penetration in brain and testis J. Pharmacol. Exp. Ther. 281 1997 1226 1230
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.281
, pp. 1226-1230
-
-
Arboix, M.1
Paz, O.G.2
Colombo, T.3
D'Incalci, M.4
-
4
-
-
0032843082
-
P-glycoprotein secretory transport and other barriers to the oral delivery of anti-HIV drugs
-
B.J. Aungst P-glycoprotein secretory transport and other barriers to the oral delivery of anti-HIV drugs Adv. Drug. Deliv. Rev. 39 1999 105 116
-
(1999)
Adv. Drug. Deliv. Rev.
, vol.39
, pp. 105-116
-
-
Aungst, B.J.1
-
5
-
-
0028892249
-
Comparisons of P-glycoprotein expression in isolated rat brain microvessels and in primary cultures of endothelial cells derived from microvasculature of rat brain, epididymal fat pad and from aorta
-
M.A. Barrand, K.J. Robertson, and S.F. von Weikersthal Comparisons of P-glycoprotein expression in isolated rat brain microvessels and in primary cultures of endothelial cells derived from microvasculature of rat brain, epididymal fat pad and from aorta FEBS Lett. 374 1995 179 183
-
(1995)
FEBS Lett.
, vol.374
, pp. 179-183
-
-
Barrand, M.A.1
Robertson, K.J.2
Von Weikersthal, S.F.3
-
6
-
-
0036075392
-
An oncological view on the blood-testis barrier
-
J. Bart, H.J. Groen, W.T. van der Graaf, H. Hollema, N.H. Hendrikse, W. Vaalburg, D.T. Sleijfer, and E.G. de Vries An oncological view on the blood-testis barrier Lancet Oncol. 3 2002 357 363
-
(2002)
Lancet Oncol.
, vol.3
, pp. 357-363
-
-
Bart, J.1
Groen, H.J.2
Van Der Graaf, W.T.3
Hollema, H.4
Hendrikse, N.H.5
Vaalburg, W.6
Sleijfer, D.T.7
De Vries, E.G.8
-
7
-
-
0034751938
-
Effect of grapefruit juice on digoxin pharmacokinetics in humans
-
L. Becquemont, C. Verstuyft, R. Kerb, U. Brinkmann, M. Lebot, P. Jaillon, and C. Funck-Brentano Effect of grapefruit juice on digoxin pharmacokinetics in humans Clin. Pharmacol. Ther. 70 2001 311 316
-
(2001)
Clin. Pharmacol. Ther.
, vol.70
, pp. 311-316
-
-
Becquemont, L.1
Verstuyft, C.2
Kerb, R.3
Brinkmann, U.4
Lebot, M.5
Jaillon, P.6
Funck-Brentano, C.7
-
8
-
-
0029563319
-
Cardiotoxicity in the SCID mouse following administration of doxorubicin and cyclosporin a
-
W.T. Bellamy, Y.M. Peng, A. Odeleye, L. Ellsworth, M.J. Xu, T.M. Grogan, and R.S. Weinstein Cardiotoxicity in the SCID mouse following administration of doxorubicin and cyclosporin A Anticancer Drugs 6 1995 736 743
-
(1995)
Anticancer Drugs
, vol.6
, pp. 736-743
-
-
Bellamy, W.T.1
Peng, Y.M.2
Odeleye, A.3
Ellsworth, L.4
Xu, M.J.5
Grogan, T.M.6
Weinstein, R.S.7
-
9
-
-
0036070626
-
Piperine, a major constituent of black pepper, inhibits human P-glycoprotein and CYP3A4
-
R.K. Bhardwaj, H. Glaeser, L. Becquemont, U. Klotz, S.K. Gupta, and M.F. Fromm Piperine, a major constituent of black pepper, inhibits human P-glycoprotein and CYP3A4 J. Pharmacol. Exp. Ther. 302 2002 645 650
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.302
, pp. 645-650
-
-
Bhardwaj, R.K.1
Glaeser, H.2
Becquemont, L.3
Klotz, U.4
Gupta, S.K.5
Fromm, M.F.6
-
10
-
-
0028131907
-
Multidrug resistance gene (MDR 1) expression in neuro-axial tumours of children and young adults
-
A.L. Billson, J.B. Palmer, D.A. Walker, and J. Lowe Multidrug resistance gene (MDR 1) expression in neuro-axial tumours of children and young adults Brit. J. Neurosurg. 8 1994 585 591
-
(1994)
Brit. J. Neurosurg.
, vol.8
, pp. 585-591
-
-
Billson, A.L.1
Palmer, J.B.2
Walker, D.A.3
Lowe, J.4
-
11
-
-
0037111469
-
Toxicologic and pharmacokinetic study of low doses of verapamil combined with doxorubicin
-
L. Candussio, G. Decorti, E. Crivellato, M. Granzotto, A. Rosati, T. Giraldi, and F. Bartoli Toxicologic and pharmacokinetic study of low doses of verapamil combined with doxorubicin Life Sci. 71 2002 3109 3119
-
(2002)
Life Sci.
, vol.71
, pp. 3109-3119
-
-
Candussio, L.1
Decorti, G.2
Crivellato, E.3
Granzotto, M.4
Rosati, A.5
Giraldi, T.6
Bartoli, F.7
-
12
-
-
0034888307
-
Affinity for the P-glycoprotein efflux pump at the blood-brain barrier may explain the lack of CNS side-effects of modern antihistamines
-
M. Chishty, A. Reichel, J. Siva, N.J. Abbott, and D.J. Begley Affinity for the P-glycoprotein efflux pump at the blood-brain barrier may explain the lack of CNS side-effects of modern antihistamines J. Drug Target. 9 2001 223 228
-
(2001)
J. Drug Target.
, vol.9
, pp. 223-228
-
-
Chishty, M.1
Reichel, A.2
Siva, J.3
Abbott, N.J.4
Begley, D.J.5
-
13
-
-
0034121122
-
Pharmacological inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain and testes
-
E.F. Choo, B. Leake, C. Wandel, H. Imamura, A.J. Wood, G.R. Wilkinson, and R.B. Kim Pharmacological inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain and testes Drug Metab. Dipos. 28 2000 655 660
-
(2000)
Drug Metab. Dipos.
, vol.28
, pp. 655-660
-
-
Choo, E.F.1
Leake, B.2
Wandel, C.3
Imamura, H.4
Wood, A.J.5
Wilkinson, G.R.6
Kim, R.B.7
-
14
-
-
0028325437
-
Cyclosporin a markedly changes the distribution of doxorubicin in mice and rats
-
T. Colombo, M. Zucchetti, and M. D'Incalci Cyclosporin A markedly changes the distribution of doxorubicin in mice and rats J. Pharmacol. Exp. Ther. 269 1994 22 27
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.269
, pp. 22-27
-
-
Colombo, T.1
Zucchetti, M.2
D'Incalci, M.3
-
15
-
-
0000712439
-
Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites
-
C. Cordon-Cardo, J.P. O'Brien, D. Casals, L. Rittman-Grauer, J.L. Biedler, M.R. Melamed, and J.R. Bertino Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites Proc. Natl. Acad. Sci. U.S.A. 86 1989 695 698
-
(1989)
Proc. Natl. Acad. Sci. U.S.A.
, vol.86
, pp. 695-698
-
-
Cordon-Cardo, C.1
O'Brien, J.P.2
Casals, D.3
Rittman-Grauer, L.4
Biedler, J.L.5
Melamed, M.R.6
Bertino, J.R.7
-
16
-
-
0025071180
-
Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues
-
C. Cordon-Cardo, J.P. O'Brien, J. Boccia, D. Casals, J.R. Bertino, and M.R. Melamed Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues J. Histochem. Cytochem. 38 1990 1277 1287
-
(1990)
J. Histochem. Cytochem.
, vol.38
, pp. 1277-1287
-
-
Cordon-Cardo, C.1
O'Brien, J.P.2
Boccia, J.3
Casals, D.4
Bertino, J.R.5
Melamed, M.R.6
-
17
-
-
0024544045
-
The three mouse multidrug resistance (MDR) genes are expressed in a tissue-specific manner in normal mouse tissues
-
J.M. Croop, M. Raymond, D. Haber, A. Devault, R.J. Arceci, P. Gros, and D.E. Housman The three mouse multidrug resistance (MDR) genes are expressed in a tissue-specific manner in normal mouse tissues Mol. Cell. Biol. 9 1989 1346 1350
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 1346-1350
-
-
Croop, J.M.1
Raymond, M.2
Haber, D.3
Devault, A.4
Arceci, R.J.5
Gros, P.6
Housman, D.E.7
-
18
-
-
0036228349
-
Distribution of domperidone into the rat brain is increased by brain ischaemia or treatment with the P-glycoprotein inhibitor verapamil
-
Y. Dan, H. Murakami, N. Koyabu, H. Ohtani, and Y. Sawada Distribution of domperidone into the rat brain is increased by brain ischaemia or treatment with the P-glycoprotein inhibitor verapamil J. Pharm. Pharmacol. 54 2002 729 733
-
(2002)
J. Pharm. Pharmacol.
, vol.54
, pp. 729-733
-
-
Dan, Y.1
Murakami, H.2
Koyabu, N.3
Ohtani, H.4
Sawada, Y.5
-
19
-
-
0030918044
-
Effect of the P-glycoprotein inhibitor, SDZ PSC 833, on the blood and brain pharmacokinetics of colchicine
-
S. Desrayaud, P. Guntz, J.M. Scherrmann, and M. Lemaire Effect of the P-glycoprotein inhibitor, SDZ PSC 833, on the blood and brain pharmacokinetics of colchicine Life Sci. 61 1997 153 163
-
(1997)
Life Sci.
, vol.61
, pp. 153-163
-
-
Desrayaud, S.1
Guntz, P.2
Scherrmann, J.M.3
Lemaire, M.4
-
20
-
-
3042568988
-
Substantial pharmacokinetic interaction between digoxin and ritonavir in healthy volunteers
-
R. Ding, Y. Tayrouz, K.D. Riedel, J. Burhenne, J. Weiss, G. Mikus, and W.E. Haefeli Substantial pharmacokinetic interaction between digoxin and ritonavir in healthy volunteers Clin. Pharmacol. Ther. 76 2004 73 84
-
(2004)
Clin. Pharmacol. Ther.
, vol.76
, pp. 73-84
-
-
Ding, R.1
Tayrouz, Y.2
Riedel, K.D.3
Burhenne, J.4
Weiss, J.5
Mikus, G.6
Haefeli, W.E.7
-
21
-
-
0042132423
-
Expression of a multidrug-resistance gene in human tumors and tissues
-
A.T. Fojo, K. Ueda, D.J. Slamon, D.G. Poplack, M.M. Gottesman, and I. Pastan Expression of a multidrug-resistance gene in human tumors and tissues Proc. Natl. Acad. Sci. U.S.A. 84 1987 265 269
-
(1987)
Proc. Natl. Acad. Sci. U.S.A.
, vol.84
, pp. 265-269
-
-
Fojo, A.T.1
Ueda, K.2
Slamon, D.J.3
Poplack, D.G.4
Gottesman, M.M.5
Pastan, I.6
-
22
-
-
0035735338
-
An in vitro evaluation of human cytochrome P450 3A4 and P-glycoprotein inhibition by garlic
-
B.C. Foster, M.S. Foster, S. Vandenhoek, A. Krantis, J.W. Budzinski, J.T. Arnason, K.D. Gallicano, and S. Choudri An in vitro evaluation of human cytochrome P450 3A4 and P-glycoprotein inhibition by garlic J. Pharm. Pharm. Sci. 4 2001 176 184
-
(2001)
J. Pharm. Pharm. Sci.
, vol.4
, pp. 176-184
-
-
Foster, B.C.1
Foster, M.S.2
Vandenhoek, S.3
Krantis, A.4
Budzinski, J.W.5
Arnason, J.T.6
Gallicano, K.D.7
Choudri, S.8
-
23
-
-
0033514320
-
Inhibition of P-glycoprotein-mediated drug transport: A unifying mechanism to explain the interaction between digoxin and quinidine
-
M.F. Fromm, R.B. Kim, C.M. Stein, G.R. Wilkinson, and D.M. Roden Inhibition of P-glycoprotein-mediated drug transport: a unifying mechanism to explain the interaction between digoxin and quinidine Circulation 99 1999 552 557
-
(1999)
Circulation
, vol.99
, pp. 552-557
-
-
Fromm, M.F.1
Kim, R.B.2
Stein, C.M.3
Wilkinson, G.R.4
Roden, D.M.5
-
24
-
-
0024815017
-
Serum concentrations of amiodarone required for an in vivo modulation of anthracycline resistance
-
P. Genne, B. Coudert, H. Pelletier, C. Girardot, F. Martin, and B. Chauffert Serum concentrations of amiodarone required for an in vivo modulation of anthracycline resistance Anticancer Res. 9 1989 1655 1659
-
(1989)
Anticancer Res.
, vol.9
, pp. 1655-1659
-
-
Genne, P.1
Coudert, B.2
Pelletier, H.3
Girardot, C.4
Martin, F.5
Chauffert, B.6
-
25
-
-
0028980990
-
Changes in doxorubicin distribution and toxicity in mice pretreated with the cyclosporin analogue SDZ PSC 833
-
O. Gonzalez, T. Colombo, M. De Fusco, L. Imperatori, M. Zucchetti, and M. D'Incalci Changes in doxorubicin distribution and toxicity in mice pretreated with the cyclosporin analogue SDZ PSC 833 Cancer Chemother. Pharmacol. 36 1995 335 340
-
(1995)
Cancer Chemother. Pharmacol.
, vol.36
, pp. 335-340
-
-
Gonzalez, O.1
Colombo, T.2
De Fusco, M.3
Imperatori, L.4
Zucchetti, M.5
D'Incalci, M.6
-
26
-
-
0026621245
-
ABC transporters: From microorganisms to man
-
C.F. Higgins ABC transporters: from microorganisms to man Annu. Rev. Cell. Biol. 8 1992 67 113
-
(1992)
Annu. Rev. Cell. Biol.
, vol.8
, pp. 67-113
-
-
Higgins, C.F.1
-
27
-
-
0038691604
-
Lack of interaction of digoxin and P-glycoprotein inhibitors, quinidine and verapamil in human placenta in vitro
-
G. Holcberg, O. Sapir, M. Tsadkin, M. Huleihel, S. Lazer, M. Katz, M. Mazor, and Z. Ben-Zvi Lack of interaction of digoxin and P-glycoprotein inhibitors, quinidine and verapamil in human placenta in vitro Eur. J. Obstet. Gynecol. Reprod. Biol. 109 2003 133 137
-
(2003)
Eur. J. Obstet. Gynecol. Reprod. Biol.
, vol.109
, pp. 133-137
-
-
Holcberg, G.1
Sapir, O.2
Tsadkin, M.3
Huleihel, M.4
Lazer, S.5
Katz, M.6
Mazor, M.7
Ben-Zvi, Z.8
-
28
-
-
0031907402
-
Modulation of doxorubicin concentration by cyclosporin a in brain and testicular barrier tissues expressing P-glycoprotein in rats
-
C.S. Hughes, S.L. Vaden, C.A. Manaugh, G.S. Price, and L.C. Hudson Modulation of doxorubicin concentration by cyclosporin A in brain and testicular barrier tissues expressing P-glycoprotein in rats J. Neurooncol. 37 1998 45 54
-
(1998)
J. Neurooncol.
, vol.37
, pp. 45-54
-
-
Hughes, C.S.1
Vaden, S.L.2
Manaugh, C.A.3
Price, G.S.4
Hudson, L.C.5
-
29
-
-
0033724903
-
Influence of antipsychotic, antiemetic, and Ca(2+) channel blocker drugs on the cellular accumulation of the anticancer drug daunorubicin: P-glycoprotein modulation
-
S. Ibrahim, J. Peggins, A. Knapton, T. Licht, and A. Aszalos Influence of antipsychotic, antiemetic, and Ca(2+) channel blocker drugs on the cellular accumulation of the anticancer drug daunorubicin: P-glycoprotein modulation J. Pharmacol. Exp. Ther. 295 2000 1276 1283
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.295
, pp. 1276-1283
-
-
Ibrahim, S.1
Peggins, J.2
Knapton, A.3
Licht, T.4
Aszalos, A.5
-
30
-
-
0035021840
-
Influence of beta-adrenergic antagonists, H1-receptor blockers, analgesics, diuretics, and quinolone antibiotics on the cellular accumulation of the anticancer drug, daunorubicin: P-glycoprotein modulation
-
S. Ibrahim, J. Peggins, A. Knapton, T. Licht, and A. Aszalos Influence of beta-adrenergic antagonists, H1-receptor blockers, analgesics, diuretics, and quinolone antibiotics on the cellular accumulation of the anticancer drug, daunorubicin: P-glycoprotein modulation Anticancer Res. 21 2001 847 856
-
(2001)
Anticancer Res.
, vol.21
, pp. 847-856
-
-
Ibrahim, S.1
Peggins, J.2
Knapton, A.3
Licht, T.4
Aszalos, A.5
-
32
-
-
0035866385
-
The pharmacological phenotype of combined multidrug-resistance mdr1a/1b- and mrp1-deficient mice
-
D.R. Johnson, R.A. Finch, Z.P. Lin, C.J. Zeiss, and A.C. Sartorelli The pharmacological phenotype of combined multidrug-resistance mdr1a/1b- and mrp1-deficient mice Cancer Res. 61 2001 1469 1476
-
(2001)
Cancer Res.
, vol.61
, pp. 1469-1476
-
-
Johnson, D.R.1
Finch, R.A.2
Lin, Z.P.3
Zeiss, C.J.4
Sartorelli, A.C.5
-
33
-
-
0032960014
-
Role of blood-brain barrier P-glycoprotein in limiting brain accumulation and sedative side-effects of asimadoline, a peripherally acting analgesic drug
-
J.W. Jonker, E. Wagenaar, L. Van Deemter, R. Gottschlich, H.M. Bender, J. Dasenbrock, and A.H. Schinkel Role of blood-brain barrier P-glycoprotein in limiting brain accumulation and sedative side-effects of asimadoline, a peripherally acting analgesic drug Brit. J. Pharmacol. 127 1999 43 50
-
(1999)
Brit. J. Pharmacol.
, vol.127
, pp. 43-50
-
-
Jonker, J.W.1
Wagenaar, E.2
Van Deemter, L.3
Gottschlich, R.4
Bender, H.M.5
Dasenbrock, J.6
Schinkel, A.H.7
-
34
-
-
33645830172
-
A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
-
R.L. Juliano, and V. Ling A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants Biochim. Biophys. Acta 455 1976 152 162
-
(1976)
Biochim. Biophys. Acta
, vol.455
, pp. 152-162
-
-
Juliano, R.L.1
Ling, V.2
-
35
-
-
0034751371
-
Influence of P-glycoprotein modulators on cardiac uptake, metabolism, and effects of idarubicin
-
W. Kang, and M. Weiss Influence of P-glycoprotein modulators on cardiac uptake, metabolism, and effects of idarubicin Pharm. Res. 18 2001 1535 1541
-
(2001)
Pharm. Res.
, vol.18
, pp. 1535-1541
-
-
Kang, W.1
Weiss, M.2
-
36
-
-
0020578356
-
Cell surface P-glycoprotein associated with multidrug resistance in mammalian cell lines
-
N. Kartner, J.R. Riordan, and V. Ling Cell surface P-glycoprotein associated with multidrug resistance in mammalian cell lines Science 221 1983 1285 1288
-
(1983)
Science
, vol.221
, pp. 1285-1288
-
-
Kartner, N.1
Riordan, J.R.2
Ling, V.3
-
37
-
-
0037212768
-
Reversal of P-glycoprotein-mediated multidrug resistance by ginsenoside Rg(3)
-
S.W. Kim, H.Y. Kwon, D.W. Chi, J.H. Shim, J.D. Park, Y.H. Lee, S. Pyo, and D.K. Rhee Reversal of P-glycoprotein-mediated multidrug resistance by ginsenoside Rg(3) Biochem. Pharmacol. 65 2003 75 82
-
(2003)
Biochem. Pharmacol.
, vol.65
, pp. 75-82
-
-
Kim, S.W.1
Kwon, H.Y.2
Chi, D.W.3
Shim, J.H.4
Park, J.D.5
Lee, Y.H.6
Pyo, S.7
Rhee, D.K.8
-
38
-
-
0032129118
-
Placental P-glycoprotein deficiency enhances susceptibility to chemically induced birth defects in mice
-
G.R. Lankas, L.D. Wise, M.E. Cartwright, T. Pippert, and D.R. Umbenhauer Placental P-glycoprotein deficiency enhances susceptibility to chemically induced birth defects in mice Reprod. Toxicol. 12 1998 457 463
-
(1998)
Reprod. Toxicol.
, vol.12
, pp. 457-463
-
-
Lankas, G.R.1
Wise, L.D.2
Cartwright, M.E.3
Pippert, T.4
Umbenhauer, D.R.5
-
39
-
-
0033060742
-
Effects of a potent and specific P-glycoprotein inhibitor on the blood-brain barrier distribution and antinociceptive effect of morphine in the rat
-
S.P. Letrent, G.M. Pollack, K.R. Brouwer, and L.R. Brouwer Effects of a potent and specific P-glycoprotein inhibitor on the blood-brain barrier distribution and antinociceptive effect of morphine in the rat Drug Metab. Dipos. 27 1999 827 834
-
(1999)
Drug Metab. Dipos.
, vol.27
, pp. 827-834
-
-
Letrent, S.P.1
Pollack, G.M.2
Brouwer, K.R.3
Brouwer, L.R.4
-
40
-
-
0037457793
-
Drug-drug interaction mediated by inhibition and induction of P-glycoprotein
-
J.H. Lin Drug-drug interaction mediated by inhibition and induction of P-glycoprotein Adv. Drug. Deliv. Rev. 55 2003 53 81
-
(2003)
Adv. Drug. Deliv. Rev.
, vol.55
, pp. 53-81
-
-
Lin, J.H.1
-
41
-
-
0029963038
-
The role of multidrug resistance and its pharmacological modulation in acute myeloid leukemia
-
A.F. List The role of multidrug resistance and its pharmacological modulation in acute myeloid leukemia Leukemia 10 1996 36 38
-
(1996)
Leukemia
, vol.10
, pp. 36-38
-
-
List, A.F.1
-
42
-
-
0036799701
-
Increased CNS uptake and enhanced antinociception of morphine-6- glucuronide in rats after inhibition of P-glycoprotein
-
J. Lötsch, R. Schmidt, G. Vetter, H. Schmidt, E. Niederberger, G. Geisslinger, and I. Tegeder Increased CNS uptake and enhanced antinociception of morphine-6-glucuronide in rats after inhibition of P-glycoprotein J. Neurochem. 83 2002 241 248
-
(2002)
J. Neurochem.
, vol.83
, pp. 241-248
-
-
Lötsch, J.1
Schmidt, R.2
Vetter, G.3
Schmidt, H.4
Niederberger, E.5
Geisslinger, G.6
Tegeder, I.7
-
43
-
-
0035987163
-
Dose-dependent increase of saquinavir bioavailability by the pharmaceutic aid cremophor EL
-
M. Martin-Facklam, J. Burhenne, R. Ding, R. Fricker, G. Mikus, I. Walter-Sack, and W.E. Haefeli Dose-dependent increase of saquinavir bioavailability by the pharmaceutic aid cremophor EL Brit. J. Clin. Pharmacol. 53 2002 576 581
-
(2002)
Brit. J. Clin. Pharmacol.
, vol.53
, pp. 576-581
-
-
Martin-Facklam, M.1
Burhenne, J.2
Ding, R.3
Fricker, R.4
Mikus, G.5
Walter-Sack, I.6
Haefeli, W.E.7
-
44
-
-
0031587981
-
Function of P-glycoprotein expressed in placenta and mole
-
Y. Nakamura, S. Ikeda, T. Furukawa, T. Sumizawa, A. Tani, S. Akiyama, and Y. Nagata Function of P-glycoprotein expressed in placenta and mole Biochem. Biophys. Res. Commun. 235 1997 849 853
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.235
, pp. 849-853
-
-
Nakamura, Y.1
Ikeda, S.2
Furukawa, T.3
Sumizawa, T.4
Tani, A.5
Akiyama, S.6
Nagata, Y.7
-
45
-
-
0031958040
-
Relative tissue distributions of cyclosporin and sirolimus after concomitant peroral administration to the rat: Evidence for pharmacokinetic interactions
-
K.L. Napoli, M.E. Wang, S.M. Stepkowski, and B.D. Kahan Relative tissue distributions of cyclosporin and sirolimus after concomitant peroral administration to the rat: evidence for pharmacokinetic interactions Ther. Drug Monit. 20 1998 123 133
-
(1998)
Ther. Drug Monit.
, vol.20
, pp. 123-133
-
-
Napoli, K.L.1
Wang, M.E.2
Stepkowski, S.M.3
Kahan, B.D.4
-
46
-
-
3342912248
-
P-glycoprotein expression and distribution in the rat placenta during pregnancy
-
M. Novotna, A. Libra, M. Kopecky, P. Pavek, Z. Fendrich, V. Semecky, and F. Staud P-glycoprotein expression and distribution in the rat placenta during pregnancy Reprod. Toxicol. 18 2004 785 792
-
(2004)
Reprod. Toxicol.
, vol.18
, pp. 785-792
-
-
Novotna, M.1
Libra, A.2
Kopecky, M.3
Pavek, P.4
Fendrich, Z.5
Semecky, V.6
Staud, F.7
-
47
-
-
0001370913
-
Uncoupling of biliary phospholipid and cholesterol secretion in mice with reduced expression of mdr2 P-glycoprotein
-
R.P. Oude Elferink, R. Ottenhoff, M. van Wijland, C.M. Frijters, C. van Nieuwkerk, and A.K. Groen Uncoupling of biliary phospholipid and cholesterol secretion in mice with reduced expression of mdr2 P-glycoprotein J. Lipid Res. 37 1996 1065 1075
-
(1996)
J. Lipid Res.
, vol.37
, pp. 1065-1075
-
-
Oude Elferink, R.P.1
Ottenhoff, R.2
Van Wijland, M.3
Frijters, C.M.4
Van Nieuwkerk, C.5
Groen, A.K.6
-
48
-
-
0035214120
-
Interaction of omeprazole, lansoprazole and pantoprazole with P-glycoprotein
-
C. Pauli-Magnus, S. Rekersbrink, U. Klotz, and M.F. Fromm Interaction of omeprazole, lansoprazole and pantoprazole with P-glycoprotein Naunyn Schmiedebergs Arch. Pharmacol. 364 2001 551 557
-
(2001)
Naunyn Schmiedebergs Arch. Pharmacol.
, vol.364
, pp. 551-557
-
-
Pauli-Magnus, C.1
Rekersbrink, S.2
Klotz, U.3
Fromm, M.F.4
-
49
-
-
0036646107
-
Transport of phosphatidylserine via MDR1 (multidrug resistance 1) P-glycoprotein in a human gastric carcinoma cell line
-
A. Pohl, H. Lage, P. Muller, T. Pomorski, and A. Herrmann Transport of phosphatidylserine via MDR1 (multidrug resistance 1) P-glycoprotein in a human gastric carcinoma cell line Biochem. J. 365 2002 259 268
-
(2002)
Biochem. J.
, vol.365
, pp. 259-268
-
-
Pohl, A.1
Lage, H.2
Muller, P.3
Pomorski, T.4
Herrmann, A.5
-
50
-
-
0032804327
-
Role of P-glycoprotein on the CNS disposition of amprenavir (141W94), an HIV protease inhibitor
-
J.W. Polli, J.L. Jarrett, S.D. Studenberg, J.E. Humphreys, S.W. Dennis, K.R. Brouwer, and J.L. Woolley Role of P-glycoprotein on the CNS disposition of amprenavir (141W94), an HIV protease inhibitor Pharm. Res. 16 1999 1206 1212
-
(1999)
Pharm. Res.
, vol.16
, pp. 1206-1212
-
-
Polli, J.W.1
Jarrett, J.L.2
Studenberg, S.D.3
Humphreys, J.E.4
Dennis, S.W.5
Brouwer, K.R.6
Woolley, J.L.7
-
51
-
-
0035900333
-
P-glycoprotein and multidrug resistance-associated protein are involved in the regulation of extracellular levels of the major antiepileptic drug carbamazepine in the brain
-
H. Potschka, M. Fedrowitz, and W. Loscher P-glycoprotein and multidrug resistance-associated protein are involved in the regulation of extracellular levels of the major antiepileptic drug carbamazepine in the brain Neuroreport 12 2001 3557 3560
-
(2001)
Neuroreport
, vol.12
, pp. 3557-3560
-
-
Potschka, H.1
Fedrowitz, M.2
Loscher, W.3
-
52
-
-
0035167174
-
In vivo evidence for P-glycoprotein-mediated transport of phenytoin at the blood-brain barrier of rats
-
H. Potschka, and W. Loscher In vivo evidence for P-glycoprotein-mediated transport of phenytoin at the blood-brain barrier of rats Epilepsia 42 2001 1231 1240
-
(2001)
Epilepsia
, vol.42
, pp. 1231-1240
-
-
Potschka, H.1
Loscher, W.2
-
53
-
-
0037178642
-
P-glycoprotein-mediated efflux of phenobarbital, lamotrigine, and felbamate at the blood-brain barrier: Evidence from microdialysis experiments in rats
-
H. Potschka, M. Fedrowitz, and W. Loscher P-glycoprotein-mediated efflux of phenobarbital, lamotrigine, and felbamate at the blood-brain barrier: evidence from microdialysis experiments in rats Neurosci. Lett. 327 2002 173 176
-
(2002)
Neurosci. Lett.
, vol.327
, pp. 173-176
-
-
Potschka, H.1
Fedrowitz, M.2
Loscher, W.3
-
54
-
-
0032523916
-
Effects of curcumin on P-glycoprotein in primary cultures of rat hepatocytes
-
N. Romiti, R. Tongiani, F. Cervelli, and E. Chieli Effects of curcumin on P-glycoprotein in primary cultures of rat hepatocytes Life Sci. 62 1998 2349 2358
-
(1998)
Life Sci.
, vol.62
, pp. 2349-2358
-
-
Romiti, N.1
Tongiani, R.2
Cervelli, F.3
Chieli, E.4
-
55
-
-
0033833430
-
Increased drug delivery to the brain by P-glycoprotein inhibition
-
A.J. Sadeque, C. Wandel, H. He, S. Shah, and A.J. Wood Increased drug delivery to the brain by P-glycoprotein inhibition Clin. Pharmacol. Ther. 68 2000 231 237
-
(2000)
Clin. Pharmacol. Ther.
, vol.68
, pp. 231-237
-
-
Sadeque, A.J.1
Wandel, C.2
He, H.3
Shah, S.4
Wood, A.J.5
-
56
-
-
0030763371
-
P-glycoprotein expression in capillary endothelial cells of the 7th and 8th nerves of guinea pig in relation to blood-nerve barrier sites
-
T. Saito, Z.J. Zhang, Y. Shibamori, T. Ohtsubo, I. Noda, T. Yamamoto, and H. Saito P-glycoprotein expression in capillary endothelial cells of the 7th and 8th nerves of guinea pig in relation to blood-nerve barrier sites Neurosci. Lett. 232 1997 41 44
-
(1997)
Neurosci. Lett.
, vol.232
, pp. 41-44
-
-
Saito, T.1
Zhang, Z.J.2
Shibamori, Y.3
Ohtsubo, T.4
Noda, I.5
Yamamoto, T.6
Saito, H.7
-
57
-
-
0035906533
-
Cyclosporin a inhibits the extrusion pump function of p-glycoprotein in the inner ear of mice treated with vinblastine and doxorubicin
-
T. Saito, Z.J. Zhang, M. Tokuriki, T. Ohtsubo, Y. Shibamori, T. Yamamoto, and H. Saito Cyclosporin A inhibits the extrusion pump function of p-glycoprotein in the inner ear of mice treated with vinblastine and doxorubicin Brain Res. 901 2001 265 270
-
(2001)
Brain Res.
, vol.901
, pp. 265-270
-
-
Saito, T.1
Zhang, Z.J.2
Tokuriki, M.3
Ohtsubo, T.4
Shibamori, Y.5
Yamamoto, T.6
Saito, H.7
-
58
-
-
0028229150
-
Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
-
A.H. Schinkel, J.J. Smit, O. van Tellingen, J.H. Beijnen, E. Wagenaar, L. van Deemter, C.A. Mol, M.A. van der Valk, E.C. Robanus-Maandag, H.P. te Riele, A.J.M. Berns, and P. Borst Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs Cell 7 1994 491 502
-
(1994)
Cell
, vol.7
, pp. 491-502
-
-
Schinkel, A.H.1
Smit, J.J.2
Van Tellingen, O.3
Beijnen, J.H.4
Wagenaar, E.5
Van Deemter, L.6
Mol, C.A.7
Van Der Valk, M.A.8
Robanus-Maandag, E.C.9
Te Riele, H.P.10
Berns, A.J.M.11
Borst, P.12
-
59
-
-
0028825399
-
Absence of the mdr1a P-glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin a
-
A.H. Schinkel, E. Wagenaar, L. van Deemter, C.A. Mol, and P. Borst Absence of the mdr1a P-glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A J. Clin. Invest. 96 1995 1698 1705
-
(1995)
J. Clin. Invest.
, vol.96
, pp. 1698-1705
-
-
Schinkel, A.H.1
Wagenaar, E.2
Van Deemter, L.3
Mol, C.A.4
Borst, P.5
-
60
-
-
0037457802
-
Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: An overview
-
A.H. Schinkel, and J.W. Jonker Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview Adv. Drug. Deliv. Rev. 55 2003 3 29
-
(2003)
Adv. Drug. Deliv. Rev.
, vol.55
, pp. 3-29
-
-
Schinkel, A.H.1
Jonker, J.W.2
-
61
-
-
0034111043
-
P-glycoprotein inhibitor erythromycin increases oral bioavailability of talinolol in humans
-
U.I. Schwarz, T. Gramatte, J. Krappweis, R. Oertel, and W. Kirch P-glycoprotein inhibitor erythromycin increases oral bioavailability of talinolol in humans Int. J. Clin. Pharmacol. Ther. 38 2000 161 167
-
(2000)
Int. J. Clin. Pharmacol. Ther.
, vol.38
, pp. 161-167
-
-
Schwarz, U.I.1
Gramatte, T.2
Krappweis, J.3
Oertel, R.4
Kirch, W.5
-
62
-
-
0038147266
-
Rhabdomyolysis causing av blockade due to possible atorvastatin, esomeprazole, and clarithromycin interaction
-
B.E. Sipe, R.J. Jones, and G.H. Bokhart Rhabdomyolysis causing av blockade due to possible atorvastatin, esomeprazole, and clarithromycin interaction Ann. Pharmacother. 37 2003 808 811
-
(2003)
Ann. Pharmacother.
, vol.37
, pp. 808-811
-
-
Sipe, B.E.1
Jones, R.J.2
Bokhart, G.H.3
-
63
-
-
0032701128
-
Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure
-
J.W. Smit, M.T. Huisman, O. van Tellingen, H.R. Wiltshire, and A.H. Schinkel Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure J. Clin. Invest. 104 1999 1441 1447
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 1441-1447
-
-
Smit, J.W.1
Huisman, M.T.2
Van Tellingen, O.3
Wiltshire, H.R.4
Schinkel, A.H.5
-
64
-
-
0032904977
-
Grapefruit juice activates P-glycoprotein-mediated drug transport
-
A. Soldner, U. Christians, M. Susanto, V.J. Wacher, J.A. Silverman, and L.Z. Benet Grapefruit juice activates P-glycoprotein-mediated drug transport Pharm. Res. 16 1999 478 485
-
(1999)
Pharm. Res.
, vol.16
, pp. 478-485
-
-
Soldner, A.1
Christians, U.2
Susanto, M.3
Wacher, V.J.4
Silverman, J.A.5
Benet, L.Z.6
-
65
-
-
0031962002
-
P-glycoprotein transporters and the gastrointestinal tract: Evaluation of the potential in vivo relevance of in vitro data employing talinolol as model compound
-
H. Spahn-Langguth, G. Baktir, A. Radschuweit, A. Okyar, B. Terhaag, P. Ader, A. Hanafy, and P. Langguth P-glycoprotein transporters and the gastrointestinal tract: evaluation of the potential in vivo relevance of in vitro data employing talinolol as model compound Int. J. Clin. Pharmacol. Ther. 36 1998 16 24
-
(1998)
Int. J. Clin. Pharmacol. Ther.
, vol.36
, pp. 16-24
-
-
Spahn-Langguth, H.1
Baktir, G.2
Radschuweit, A.3
Okyar, A.4
Terhaag, B.5
Ader, P.6
Hanafy, A.7
Langguth, P.8
-
66
-
-
0035108539
-
Grapefruit juice enhances intestinal absorption of the P-glycoprotein substrate talinolol
-
H. Spahn-Langguth, and P. Langguth Grapefruit juice enhances intestinal absorption of the P-glycoprotein substrate talinolol Eur. J. Pharm. Sci. 12 2001 361 367
-
(2001)
Eur. J. Pharm. Sci.
, vol.12
, pp. 361-367
-
-
Spahn-Langguth, H.1
Langguth, P.2
-
67
-
-
12644278301
-
Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine
-
A. Sparreboom, J. van Asperen, U. Mayer, A.H. Schinkel, J.W. Smit, D.K. Meijer, P. Borst, W.J. Nooijen, J.H. Beijnen, and O. van Tellingen Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine Proc. Natl. Acad. Sci. U.S.A. 94 1997 2031 2035
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 2031-2035
-
-
Sparreboom, A.1
Van Asperen, J.2
Mayer, U.3
Schinkel, A.H.4
Smit, J.W.5
Meijer, D.K.6
Borst, P.7
Nooijen, W.J.8
Beijnen, J.H.9
Van Tellingen, O.10
-
69
-
-
0037204543
-
Progress in understanding the structure-activity relationships of P-glycoprotein
-
T.R. Stouch, and O. Gudmundsson Progress in understanding the structure-activity relationships of P-glycoprotein Adv. Drug. Deliv. Rev. 54 2002 315 328
-
(2002)
Adv. Drug. Deliv. Rev.
, vol.54
, pp. 315-328
-
-
Stouch, T.R.1
Gudmundsson, O.2
-
70
-
-
9044245300
-
Inhibition of the intestinal digoxin absorption and exsorption by quinidine
-
S.F. Su, and J.D. Huang Inhibition of the intestinal digoxin absorption and exsorption by quinidine Drug Metab. Dispos. 24 1996 142 147
-
(1996)
Drug Metab. Dispos.
, vol.24
, pp. 142-147
-
-
Su, S.F.1
Huang, J.D.2
-
71
-
-
0033739725
-
Role of metabolic enzymes and efflux transporters in the absorption of drugs from the small intestine
-
H. Suzuki, and Y. Sugiyama Role of metabolic enzymes and efflux transporters in the absorption of drugs from the small intestine Eur. J. Pharm. Sci. 12 2000 3 12
-
(2000)
Eur. J. Pharm. Sci.
, vol.12
, pp. 3-12
-
-
Suzuki, H.1
Sugiyama, Y.2
-
72
-
-
0031790854
-
Inhibition of vinblastine efflux mediated by P-glycoprotein by grapefruit juice components in caco-2 cells
-
H. Takanaga, A. Ohnishi, H. Matsuo, and Y. Sawada Inhibition of vinblastine efflux mediated by P-glycoprotein by grapefruit juice components in caco-2 cells Biol. Pharm. Bull. 21 1998 1062 1066
-
(1998)
Biol. Pharm. Bull.
, vol.21
, pp. 1062-1066
-
-
Takanaga, H.1
Ohnishi, A.2
Matsuo, H.3
Sawada, Y.4
-
73
-
-
0037799910
-
Pharmacokinetic and pharmaceutic interaction between digoxin and Cremophor RH40
-
Y. Tayrouz, R. Ding, J. Burhenne, K.D. Riedel, J. Weiss, T. Hoppe-Tichy, W.E. Haefeli, and G. Mikus Pharmacokinetic and pharmaceutic interaction between digoxin and Cremophor RH40 Clin. Pharmacol. Ther. 73 2003 397 405
-
(2003)
Clin. Pharmacol. Ther.
, vol.73
, pp. 397-405
-
-
Tayrouz, Y.1
Ding, R.2
Burhenne, J.3
Riedel, K.D.4
Weiss, J.5
Hoppe-Tichy, T.6
Haefeli, W.E.7
Mikus, G.8
-
74
-
-
0023447098
-
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues
-
F. Thiebaut, T. Tsuruo, H. Hamada, M.M. Gottesman, I. Pastan, and M.C. Willingham Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues Proc. Natl. Acad. Sci. U.S.A. 84 1987 7735 7738
-
(1987)
Proc. Natl. Acad. Sci. U.S.A.
, vol.84
, pp. 7735-7738
-
-
Thiebaut, F.1
Tsuruo, T.2
Hamada, H.3
Gottesman, M.M.4
Pastan, I.5
Willingham, M.C.6
-
75
-
-
0024576304
-
Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: Evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein
-
F. Thiebaut, T. Tsuruo, H. Hamada, M.M. Gottesman, I. Pastan, and M.C. Willingham Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein J. Histochem. Cytochem. 37 1989 159 164
-
(1989)
J. Histochem. Cytochem.
, vol.37
, pp. 159-164
-
-
Thiebaut, F.1
Tsuruo, T.2
Hamada, H.3
Gottesman, M.M.4
Pastan, I.5
Willingham, M.C.6
-
76
-
-
0026487058
-
Human P-glycoprotein transports cortisol, aldosterone and dexamethasone, but not progesterone
-
K. Ueda, N. Okamura, M. Hirai, Y. Tanigawara, T. Saeki, N. Kioka, T. Komano, and R. Hori Human P-glycoprotein transports cortisol, aldosterone and dexamethasone, but not progesterone J. Biol. Chem. 267 1992 24248 24252
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 24248-24252
-
-
Ueda, K.1
Okamura, N.2
Hirai, M.3
Tanigawara, Y.4
Saeki, T.5
Kioka, N.6
Komano, T.7
Hori, R.8
-
77
-
-
0034634387
-
Human placental transport of vinblastine, vincristine, digoxin and progesterone: Contribution of P-glycoprotein
-
F. Ushigome, H. Takanaga, H. Matsuo, S. Yanai, K. Tsukimori, H. Nakano, T. Uchiumi, T. Nakamura, M. Kuwano, H. Ohtani, and Y. Sawada Human placental transport of vinblastine, vincristine, digoxin and progesterone: contribution of P-glycoprotein Eur. J. Pharmacol. 408 2000 1 10
-
(2000)
Eur. J. Pharmacol.
, vol.408
, pp. 1-10
-
-
Ushigome, F.1
Takanaga, H.2
Matsuo, H.3
Yanai, S.4
Tsukimori, K.5
Nakano, H.6
Uchiumi, T.7
Nakamura, T.8
Kuwano, M.9
Ohtani, H.10
Sawada, Y.11
-
78
-
-
0029952418
-
Altered pharmacokinetics of vinblastine in Mdr1a P-glycoprotein-deficient mice
-
J. van Asperen, A.H. Schinkel, J.H. Beijnen, W.J. Nooijen, P. Borst, and O. van Tellingen Altered pharmacokinetics of vinblastine in Mdr1a P-glycoprotein-deficient mice J. Natl. Cancer Inst. 88 1996 994 999
-
(1996)
J. Natl. Cancer Inst.
, vol.88
, pp. 994-999
-
-
Van Asperen, J.1
Schinkel, A.H.2
Beijnen, J.H.3
Nooijen, W.J.4
Borst, P.5
Van Tellingen, O.6
-
79
-
-
0030613634
-
Enhanced oral bioavailability of paclitaxel in mice treated with the P-glycoprotein blocker SDZ PSC 833
-
J. van Asperen, O. van Tellingen, A. Sparreboom, A.H. Schinkel, P. Borst, W.J. Nooijen, and J.H. Beijnen Enhanced oral bioavailability of paclitaxel in mice treated with the P-glycoprotein blocker SDZ PSC 833 Brit. J. Cancer 76 1997 1181 1183
-
(1997)
Brit. J. Cancer
, vol.76
, pp. 1181-1183
-
-
Van Asperen, J.1
Van Tellingen, O.2
Sparreboom, A.3
Schinkel, A.H.4
Borst, P.5
Nooijen, W.J.6
Beijnen, J.H.7
-
80
-
-
0032919504
-
Comparative pharmacokinetics of vinblastine after a 96-hour continuous infusion in wild-type mice and mice lacking mdr1a P-glycoprotein
-
J. van Asperen, O. van Tellingen, A.H. Schinkel, and J.H. Beijnen Comparative pharmacokinetics of vinblastine after a 96-hour continuous infusion in wild-type mice and mice lacking mdr1a P-glycoprotein J. Pharmacol. Exp. Ther. 289 1999 329 333
-
(1999)
J. Pharmacol. Exp. Ther.
, vol.289
, pp. 329-333
-
-
Van Asperen, J.1
Van Tellingen, O.2
Schinkel, A.H.3
Beijnen, J.H.4
-
81
-
-
0034934071
-
Active efflux of the 5-HT(1A) receptor agonist flesinoxan via P-glycoprotein at the blood-brain barrier
-
I.C. van der Sandt, R. Smolders, L. Nabulsi, K.P. Zuideveld, A.G. de Boer, and D.D. Breimer Active efflux of the 5-HT(1A) receptor agonist flesinoxan via P-glycoprotein at the blood-brain barrier Eur. J. Pharm. Sci. 14 2001 81 86
-
(2001)
Eur. J. Pharm. Sci.
, vol.14
, pp. 81-86
-
-
Van Der Sandt, I.C.1
Smolders, R.2
Nabulsi, L.3
Zuideveld, K.P.4
De Boer, A.G.5
Breimer, D.D.6
-
82
-
-
0034961856
-
P-glycoprotein inhibition leads to enhanced disruptive effects by anti-microtubule cytostatics at the in vitro blood-brain barrier
-
I.C. van der Sandt, P.J. Gaillard, H.H. Voorwinden, A.G. de Boer, and D.D. Breimer P-glycoprotein inhibition leads to enhanced disruptive effects by anti-microtubule cytostatics at the in vitro blood-brain barrier Pharm. Res. 18 2001 587 592
-
(2001)
Pharm. Res.
, vol.18
, pp. 587-592
-
-
Van Der Sandt, I.C.1
Gaillard, P.J.2
Voorwinden, H.H.3
De Boer, A.G.4
Breimer, D.D.5
-
83
-
-
0031845356
-
Effect of clarithromycin on renal excretion of digoxin: Interaction with P-glycoprotein
-
H. Wakasugi, I. Yano, T. Ito, T. Hashida, T. Futami, R. Nohara, S. Sasayama, and K. Inui Effect of clarithromycin on renal excretion of digoxin: interaction with P-glycoprotein Clin. Pharmacol. Ther. 64 1998 123 128
-
(1998)
Clin. Pharmacol. Ther.
, vol.64
, pp. 123-128
-
-
Wakasugi, H.1
Yano, I.2
Ito, T.3
Hashida, T.4
Futami, T.5
Nohara, R.6
Sasayama, S.7
Inui, K.8
-
84
-
-
0034954793
-
Inhibition of P-glycoprotein transport function by grapefruit juice psoralen
-
E.J. Wang, C.N. Casciano, R.P. Clement, and W.W. Johnson Inhibition of P-glycoprotein transport function by grapefruit juice psoralen Pharm. Res. 18 2001 432 438
-
(2001)
Pharm. Res.
, vol.18
, pp. 432-438
-
-
Wang, E.J.1
Casciano, C.N.2
Clement, R.P.3
Johnson, W.W.4
-
85
-
-
0347510572
-
Lethal quercetin-digoxin interaction in pigs
-
Y.H. Wang, P.D. Chao, S.L. Hsiu, K.C. Wen, and Y.C. Hou Lethal quercetin-digoxin interaction in pigs Life Sci. 74 2004 1191 1197
-
(2004)
Life Sci.
, vol.74
, pp. 1191-1197
-
-
Wang, Y.H.1
Chao, P.D.2
Hsiu, S.L.3
Wen, K.C.4
Hou, Y.C.5
-
86
-
-
0035007337
-
Formulation and physiological and biopharmaceutical issues in the development of oral lipid-based drug delivery systems
-
K.M. Wasan Formulation and physiological and biopharmaceutical issues in the development of oral lipid-based drug delivery systems Drug Dev. Ind. Pharm. 27 2001 267 276
-
(2001)
Drug Dev. Ind. Pharm.
, vol.27
, pp. 267-276
-
-
Wasan, K.M.1
-
87
-
-
0036156298
-
P-glycoprotein inhibitors enhance saturable uptake of idarubicin in rat heart: Pharmacokinetic/pharmacodynamic modeling
-
M. Weiss, and W. Kang P-glycoprotein inhibitors enhance saturable uptake of idarubicin in rat heart: pharmacokinetic/pharmacodynamic modeling J. Pharmacol. Exp. Ther. 300 2002 688 694
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.300
, pp. 688-694
-
-
Weiss, M.1
Kang, W.2
-
88
-
-
0037379938
-
Inhibition of P-glycoprotein by newer antidepressants
-
J. Weiss, S.M. Dormann, M. Martin-Facklam, C.J. Kerpen, N. Ketabi-Kiyanvash, and W.E. Haefeli Inhibition of P-glycoprotein by newer antidepressants J. Pharmacol. Exp. Ther. 305 2003 197 204
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.305
, pp. 197-204
-
-
Weiss, J.1
Dormann, S.M.2
Martin-Facklam, M.3
Kerpen, C.J.4
Ketabi-Kiyanvash, N.5
Haefeli, W.E.6
-
89
-
-
0026707951
-
P-glycoprotein transports corticosterone and is photoaffinity-labeled by the steroid
-
D.C. Wolf, and S.B. Horwitz P-glycoprotein transports corticosterone and is photoaffinity-labeled by the steroid Int. J. Cancer 52 1992 141 146
-
(1992)
Int. J. Cancer
, vol.52
, pp. 141-146
-
-
Wolf, D.C.1
Horwitz, S.B.2
-
90
-
-
0026764698
-
Reversal of multidrug resistance by surfactants
-
D.M. Woodcock, M.E. Linsenmeyer, G. Chojnowski, A.B. Kriegler, V. Nink, L.K. Webster, and W.H. Sawyer Reversal of multidrug resistance by surfactants Brit. J. Cancer 66 1992 62 68
-
(1992)
Brit. J. Cancer
, vol.66
, pp. 62-68
-
-
Woodcock, D.M.1
Linsenmeyer, M.E.2
Chojnowski, G.3
Kriegler, A.B.4
Nink, V.5
Webster, L.K.6
Sawyer, W.H.7
-
91
-
-
0030868579
-
The digoxin-propafenone interaction: Characterization of a mechanism using renal tubular cell monolayers
-
C. Woodland, Z. Verjee, E. Giesbrecht, G. Koren, and S. Ito The digoxin-propafenone interaction: characterization of a mechanism using renal tubular cell monolayers J. Pharmacol. Exp. Ther. 283 1997 39 45
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.283
, pp. 39-45
-
-
Woodland, C.1
Verjee, Z.2
Giesbrecht, E.3
Koren, G.4
Ito, S.5
-
92
-
-
0000909084
-
The role of P-glycoprotein in blood-brain barrier transport of morphine: Transcortical microdialysis studies in mdr1a (-/-) and mdr1a (+/+) mice
-
R. Xie, M. Hammarlund-Udenaes, A.G. de Boer, and E.C. de Lange The role of P-glycoprotein in blood-brain barrier transport of morphine: transcortical microdialysis studies in mdr1a (-/-) and mdr1a (+/+) mice Brit. J. Pharmacol. 128 1999 563 568
-
(1999)
Brit. J. Pharmacol.
, vol.128
, pp. 563-568
-
-
Xie, R.1
Hammarlund-Udenaes, M.2
De Boer, A.G.3
De Lange, E.C.4
-
93
-
-
0033328139
-
The contribution of P-glycoprotein to pharmacokinetic drug-drug interactions
-
D.K. Yu The contribution of P-glycoprotein to pharmacokinetic drug-drug interactions J. Clin. Pharmacol. 39 1999 1203 1211
-
(1999)
J. Clin. Pharmacol.
, vol.39
, pp. 1203-1211
-
-
Yu, D.K.1
-
94
-
-
0033844780
-
Morphine antinociception is enhanced in mdr1a gene-deficient mice
-
J. Zong, and G.M. Pollack Morphine antinociception is enhanced in mdr1a gene-deficient mice Pharm. Res. 17 2000 749 753
-
(2000)
Pharm. Res.
, vol.17
, pp. 749-753
-
-
Zong, J.1
Pollack, G.M.2
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