Inhibition of P-glycoprotein transport function by grapefruit juice psoralen

Pharmaceutical Research

Volumn 18, Issue 4, 2001, Pages 432-438

  Wang, E J ^a   Casciano, C N ^a   Clement, R P ^a   Johnson, W W ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Drug interaction; Furanocoumarin; Grapefruit; MDR; P glycoprotein

Indexed keywords

ADENOSINE TRIPHOSPHATE; BERGAMOTTIN; CYTOCHROME P450 3A4; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN; PSORALEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MEMBRANE TRANSPORT; CITRUS FRUIT; CONTROLLED STUDY; ENZYME INACTIVATION; FOOD DRUG INTERACTION; FRUIT JUICE; GRAPEFRUIT JUICE; HYDROLYSIS; IC 50; MICHAELIS MENTEN KINETICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSPORT KINETICS;

3T3 CELLS; ADENOSINE TRIPHOSPHATE; ANIMALS; BENZIMIDAZOLES; BEVERAGES; CELL LINE; CITRUS; FICUSIN; HUMANS; HYDROLYSIS; MICE; P-GLYCOPROTEIN; PHOTOSENSITIZING AGENTS; PROTEIN TRANSPORT; PSORALENS; QUERCETIN; RADIATION-SENSITIZING AGENTS;

EID: 0034954793     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011089924099     Document Type: Article

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