Morphine antinociception is enhanced in mdr1a gene-deficient mice

Pharmaceutical Research

Volumn 17, Issue 6, 2000, Pages 749-753

  Zong, Jian ^a   Pollack, Gary M ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Anti nociception; Blood brain barrier; mdr1a( ) mice; Morphine; P glycoprotein; Pharmacodynamics

Indexed keywords

DELTA OPIATE RECEPTOR AGONIST; GLYCOPROTEIN P; MORPHINE; MU OPIATE RECEPTOR AGONIST; MULTIDRUG RESISTANCE PROTEIN; NALORPHINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; BLOOD BRAIN BARRIER; DRUG MECHANISM; DRUG PENETRATION; DRUG POTENTIATION; GENETIC DISORDER; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TISSUE DISTRIBUTION;

ANALGESICS, OPIOID; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; DRUG RESISTANCE, MULTIPLE; MALE; MICE; MICE, KNOCKOUT; MORPHINE; P-GLYCOPROTEINS; VERAPAMIL;

EID: 0033844780     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007546719287     Document Type: Article

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