The role of P-glycoprotein in blood-brain barrier transport of morphine: Transcortical microdialysis studies in mdr1a (-/-)and mdr1a (+/+) mice

British Journal of Pharmacology

Volumn 128, Issue 3, 1999, Pages 563-568

  Xie, Rujia ^b   Hammarlund Udenaes, Margareta ^b   De Boer, Albertus G ^b   De Lange, Elizabeth C M ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b NONE

Author keywords

Blood brain barrier; mdr1a ( ) mice; Microdialysis; Morphine; P glycoprotein

Indexed keywords

GLYCOPROTEIN P; MORPHINE; MORPHINE 3 GLUCURONIDE; NALORPHINE; OPIATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; CALIBRATOR; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG TRANSPORT; EXTRACELLULAR FLUID; MALE; MICRODIALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BLOOD-BRAIN BARRIER; CEREBRAL CORTEX; MICE; MICE, KNOCKOUT; MICRODIALYSIS; MORPHINE; NALORPHINE; P-GLYCOPROTEIN; P-GLYCOPROTEINS;

EID: 0000909084     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702804     Document Type: Article

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