In vivo evidence for P-glycoprotein-mediated transport of phenytoin at the blood-brain barrier of rats

Epilepsia

Volumn 42, Issue 10, 2001, Pages 1231-1240

  Potschka, Heidrun ^a   Löscher, Wolfgang ^a  

^a UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

Author keywords

Antiepileptic drugs; Epilepsy; Microdialysis; Multidrug transporters

Indexed keywords

ANTICONVULSIVE AGENT; CREMOPHOR; GLYCOPROTEIN P; PHENYTOIN; SODIUM CYANIDE; VALSPODAR; VERAPAMIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; BRAIN CORTEX; BRAIN PERFUSION; CAPILLARY; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG TRANSPORT; ENDOTHELIUM CELL; EXTRACELLULAR FLUID; FEMALE; FOCAL EPILEPSY; FRONTAL CORTEX; IN VIVO STUDY; INTRACTABLE EPILEPSY; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; ANTICONVULSANTS; BLOOD-BRAIN BARRIER; CEREBRAL CORTEX; ENDOTHELIUM, VASCULAR; FEMALE; P-GLYCOPROTEIN; PHENYTOIN; RATS; RATS, WISTAR;

EID: 0035167174     PISSN: 00139580     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1528-1157.2001.01901.x     Document Type: Article

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