-
1
-
-
13344285339
-
Identification and characterization of a new member of the TNF family that induces apoptosis
-
Wiley SR, Schooley K, Smolak PJ, Din WS, Huang CP, Nicholl JK, et al. Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 1995; 3: 673-82.
-
(1995)
Immunity
, vol.3
, pp. 673-682
-
-
Wiley, S.R.1
Schooley, K.2
Smolak, P.J.3
Din, W.S.4
Huang, C.P.5
Nicholl, J.K.6
-
2
-
-
0031905817
-
Differential regulation of TRAIL and CD95 ligand in transformed cells of the T and B lymphocyte lineage
-
Mariani SM, Krammer PH. Differential regulation of TRAIL and CD95 ligand in transformed cells of the T and B lymphocyte lineage. Eur J Immunol 1998; 28: 973-82.
-
(1998)
Eur. J. Immunol.
, vol.28
, pp. 973-982
-
-
Mariani, S.M.1
Krammer, P.H.2
-
3
-
-
0035892735
-
Differential secretion of Fas ligand- or APO2 ligand/TNF-related apoptosis-inducing ligand-carrying microvesicles during activation-induced death of human T cells
-
Monleon I, Martinez-Lorenzo MJ, Monteagudo L, Lasierra P, Taules M, Iturralde M, et al. Differential secretion of Fas ligand- or APO2 ligand/TNF-related apoptosis-inducing ligand-carrying microvesicles during activation-induced death of human T cells. J Immunol 2001; 167: 6736-44.
-
(2001)
J. Immunol.
, vol.167
, pp. 6736-6744
-
-
Monleon, I.1
Martinez-Lorenzo, M.J.2
Monteagudo, L.3
Lasierra, P.4
Taules, M.5
Iturralde, M.6
-
4
-
-
0032713075
-
Safety and antitumour activity of recombinant soluble Apo2 ligand
-
Ashkenazi A, Pai RC, Fong S, Leung S, Lawrence DA, Marsters SA, et al. Safety and antitumour activity of recombinant soluble Apo2 ligand. J Clin Invest 1999; 104: 155-62.
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 155-162
-
-
Ashkenazi, A.1
Pai, R.C.2
Fong, S.3
Leung, S.4
Lawrence, D.A.5
Marsters, S.A.6
-
5
-
-
0033974084
-
Molecular determinants of response to TRAIL in killing of normal and cancer cells
-
Kim K, Fisher MJ, Xu SQ, el Deiry WS. Molecular determinants of response to TRAIL in killing of normal and cancer cells. Clin Cancer Res 2000; 6: 335-346.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 335-346
-
-
Kim, K.1
Fisher, M.J.2
Xu, S.Q.3
el Deiry, W.S.4
-
6
-
-
0030996297
-
The receptor for the cytotoxic ligand TRAIL
-
Pan G, O'Rourke K, Chinnaiyan AM, Gentz R, Ebner R, Ni J, et al. The receptor for the cytotoxic ligand TRAIL. Science 1997a; 276: 111-3.
-
(1997)
Science
, vol.276
, pp. 111-113
-
-
Pan, G.1
O'Rourke, K.2
Chinnaiyan, A.M.3
Gentz, R.4
Ebner, R.5
Ni, J.6
-
7
-
-
0030880548
-
TRAIL-R2: A novel apoptosis-mediating receptor for TRAIL
-
Walczak H, Degli-Esposti MA, Johnson RS, Smolak PJ, Waugh JY, Boiani N, et al. TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL. EMBO J 1997; 16: 5386-97.
-
(1997)
EMBO J.
, vol.16
, pp. 5386-5397
-
-
Walczak, H.1
Degli-Esposti, M.A.2
Johnson, R.S.3
Smolak, P.J.4
Waugh, J.Y.5
Boiani, N.6
-
8
-
-
0030792712
-
Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors
-
Sheridan JP, Marsters SA, Pitti RM, Gurney A, Skubatch M, Baldwin D, et al. Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors. Science 1997; 277: 818-21.
-
(1997)
Science
, vol.277
, pp. 818-821
-
-
Sheridan, J.P.1
Marsters, S.A.2
Pitti, R.M.3
Gurney, A.4
Skubatch, M.5
Baldwin, D.6
-
9
-
-
0031253977
-
KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene
-
Wu GS, Burns TF, McDonald ER, III, Jiang W, Meng R, Krantz ID, et al. KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene. Nat Genet 1997; 17: 141-3.
-
(1997)
Nat. Genet.
, vol.17
, pp. 141-143
-
-
Wu, G.S.1
Burns, T.F.2
McDonald III, E.R.3
Jiang, W.4
Meng, R.5
Krantz, I.D.6
-
10
-
-
0030869432
-
Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family
-
Degli-Esposti MA, Smolak PJ, Walczak H, Waugh J, Huang CP, DuBose RF, et al. Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family. J Exp Med 1997a; 186: 1165-70.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1165-1170
-
-
Degli-Esposti, M.A.1
Smolak, P.J.2
Walczak, H.3
Waugh, J.4
Huang, C.P.5
DuBose, R.F.6
-
11
-
-
0030762815
-
An antagonist decoy receptor and a death domain-containing receptor for TRAIL
-
Pan G, Ni J, Wei YF, Yu G, Gentz R, Dixit VM. An antagonist decoy receptor and a death domain-containing receptor for TRAIL. Science 1997b; 277: 815-8.
-
(1997)
Science
, vol.277
, pp. 815-818
-
-
Pan, G.1
Ni, J.2
Wei, Y.F.3
Yu, G.4
Gentz, R.5
Dixit, V.M.6
-
12
-
-
13144265771
-
A novel receptor for Apo2L/TRAIL contains a truncated death domain
-
Marsters SA, Sheridan JP, Pitti RM, Huang A, Skubatch M, Baldwin D, et al. A novel receptor for Apo2L/TRAIL contains a truncated death domain. Curr Biol 1997; 7: 1003-1006.
-
(1997)
Curr. Biol.
, vol.7
, pp. 1003-1006
-
-
Marsters, S.A.1
Sheridan, J.P.2
Pitti, R.M.3
Huang, A.4
Skubatch, M.5
Baldwin, D.6
-
13
-
-
7344233085
-
Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL
-
Emery JG, McDonnell P, Burke MB, Deen KC, Lyn S, Silverman C, et al. Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL. J Biol Chem 1998; 273: 14363-67.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 14363-14367
-
-
Emery, J.G.1
McDonnell, P.2
Burke, M.B.3
Deen, K.C.4
Lyn, S.5
Silverman, C.6
-
14
-
-
0034725664
-
Temperature-sensitive differential affinity of TRAIL for its receptors. DR5 is the highest affinity receptor
-
Truneh A, Sharma S, Silverman C, Khandekar S, Reddy MP, Deen KC, et al. Temperature-sensitive differential affinity of TRAIL for its receptors. DR5 is the highest affinity receptor. J Biol Chem 2000; 275: 23319-25.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 23319-23325
-
-
Truneh, A.1
Sharma, S.2
Silverman, C.3
Khandekar, S.4
Reddy, M.P.5
Deen, K.C.6
-
15
-
-
0037086077
-
Osteoprotegerin (OPG) is a survival factor for human prostate cancer cells
-
Holen I, Croucher PI, Hamdy FC, Eaton CL. Osteoprotegerin (OPG) is a survival factor for human prostate cancer cells. Cancer Res 2002; 62: 1619-23.
-
(2002)
Cancer Res.
, vol.62
, pp. 1619-1623
-
-
Holen, I.1
Croucher, P.I.2
Hamdy, F.C.3
Eaton, C.L.4
-
17
-
-
0037273848
-
Apo2L/TRAIL and its death and decoy receptors
-
LeBlanc HN, Ashkenazi A. Apo2L/TRAIL and its death and decoy receptors. Cell Death Differ 2003; 10: 66-75.
-
(2003)
Cell Death Differ.
, vol.10
, pp. 66-75
-
-
LeBlanc, H.N.1
Ashkenazi, A.2
-
18
-
-
0037376788
-
Cell surface Death Receptor signaling in normal and cancer cells
-
Ozoren N, el Deiry WS. Cell surface Death Receptor signaling in normal and cancer cells. Semin Cancer Biol 2003; 13: 135-147.
-
(2003)
Semin. Cancer Biol.
, vol.13
, pp. 135-147
-
-
Ozoren, N.1
el Deiry, W.S.2
-
19
-
-
0033212968
-
Triggering cell death: The crystal structure of Apo2L/TRAIL in a complex with death receptor 5
-
Hymowitz SG, Christinger HW, Fuh G, Ultsch M, O'Connell M, Kelley RF, et al. Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5. Mol Cell 1999; 4: 563-71.
-
(1999)
Mol. Cell
, vol.4
, pp. 563-571
-
-
Hymowitz, S.G.1
Christinger, H.W.2
Fuh, G.3
Ultsch, M.4
O'Connell, M.5
Kelley, R.F.6
-
20
-
-
0032750511
-
Structure of the TRAIL-DR5 complex reveals mechanisms conferring specificity in apoptotic initiation
-
Mongkolsapaya J, Grimes JM, Chen N, Xu XN, Stuart DI, Jones EY, et al. Structure of the TRAIL-DR5 complex reveals mechanisms conferring specificity in apoptotic initiation. Nat Struct Biol 1999; 6: 1048-1053.
-
(1999)
Nat. Struct. Biol.
, vol.6
, pp. 1048-1053
-
-
Mongkolsapaya, J.1
Grimes, J.M.2
Chen, N.3
Xu, X.N.4
Stuart, D.I.5
Jones, E.Y.6
-
21
-
-
0034617304
-
Cysteine 2is essential for the structure and activity of the cytotoxic ligand TRAIL
-
Bodmer JL, Meier P, Tschopp J, Schneider P. Cysteine 2is essential for the structure and activity of the cytotoxic ligand TRAIL. J Biol Chem 2000a; 275: 20632-7.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 20632-20637
-
-
Bodmer, J.L.1
Meier, P.2
Tschopp, J.3
Schneider, P.4
-
22
-
-
0034142219
-
A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L/TRAIL
-
Hymowitz SG, O'Connell MP, Ultsch MH, Hurst A, Totpal K, Ashkenazi A, et al. A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L/TRAIL. Biochemistry 2000; 39: 633-40.
-
(2000)
Biochemistry
, vol.39
, pp. 633-640
-
-
Hymowitz, S.G.1
O'Connell, M.P.2
Ultsch, M.H.3
Hurst, A.4
Totpal, K.5
Ashkenazi, A.6
-
23
-
-
0035050960
-
Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions
-
Lawrence D, Shahrokh Z, Marsters S, Achilles K, Shih D, Mounho B, et al. Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions. Nat Med 2001; 7: 383-5.
-
(2001)
Nat. Med.
, vol.7
, pp. 383-385
-
-
Lawrence, D.1
Shahrokh, Z.2
Marsters, S.3
Achilles, K.4
Shih, D.5
Mounho, B.6
-
24
-
-
0032697485
-
Tumour necrosis factor-related apoptosis-inducing ligand receptors signal NF-kappaB and JNK activation and apoptosis through distinct pathways
-
Hu WH, Johnson H, Shu HB. Tumour necrosis factor-related apoptosis-inducing ligand receptors signal NF-kappaB and JNK activation and apoptosis through distinct pathways. J Biol Chem 1999; 274: 30603-10.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 30603-30610
-
-
Hu, W.H.1
Johnson, H.2
Shu, H.B.3
-
25
-
-
0031406386
-
Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway
-
Chaudhary PM, Eby M, Jasmin A, Bookwalter A, Murray J, Hood L. Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway. Immunity 1997; 7: 821-30.
-
(1997)
Immunity
, vol.7
, pp. 821-830
-
-
Chaudhary, P.M.1
Eby, M.2
Jasmin, A.3
Bookwalter, A.4
Murray, J.5
Hood, L.6
-
26
-
-
0031414749
-
The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain
-
Degli-Esposti MA, Dougall WC, Smolak PJ, Waugh JY, Smith CA, Goodwin RG. The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain. Immunity 1997b; 7: 813-20.
-
(1997)
Immunity
, vol.7
, pp. 813-820
-
-
Degli-Esposti, M.A.1
Dougall, W.C.2
Smolak, P.J.3
Waugh, J.Y.4
Smith, C.A.5
Goodwin, R.G.6
-
27
-
-
0242656497
-
Death receptor-induced cell killing
-
Thorburn A. Death receptor-induced cell killing. Cell Signal 2004; 16: 139-44.
-
(2004)
Cell Signal
, vol.16
, pp. 139-144
-
-
Thorburn, A.1
-
28
-
-
0037009370
-
Caspase-is recruited to and activated at the native TRAIL and CDdeath-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8
-
Sprick MR, Rieser E, Stahl H, Grosse-Wilde A, Weigand MA, Walczak H. Caspase-is recruited to and activated at the native TRAIL and CDdeath-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8. EMBO J 2002; 21: 4520-30.
-
(2002)
EMBO J.
, vol.21
, pp. 4520-4530
-
-
Sprick, M.R.1
Rieser, E.2
Stahl, H.3
Grosse-Wilde, A.4
Weigand, M.A.5
Walczak, H.6
-
29
-
-
0033790715
-
TRAIL receptor-2 signals apoptosis through FADD and caspase-8
-
Bodmer JL, Holler N, Reynard S, Vinciguerra P, Schneider P, Juo P, et al. TRAIL receptor-2 signals apoptosis through FADD and caspase-8, Nat Cell Biol 2000b; 2: 241-3.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 241-243
-
-
Bodmer, J.L.1
Holler, N.2
Reynard, S.3
Vinciguerra, P.4
Schneider, P.5
Juo, P.6
-
30
-
-
0034037333
-
Apoptosis induced by death receptors
-
Schneider P, Tschopp J. Apoptosis induced by death receptors. Pharm Acta Helv 2000; 74: 281-6.
-
(2000)
Pharm. Acta Helv.
, vol.74
, pp. 281-286
-
-
Schneider, P.1
Tschopp, J.2
-
31
-
-
0033662433
-
Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5 1
-
Kischkel FC, Lawrence DA, Chuntharapai A, Schow P, Kim KJ, Ashkenazi A. Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5 1. Immunity 2000; 12: 611-20.
-
(2000)
Immunity
, vol.12
, pp. 611-620
-
-
Kischkel, F.C.1
Lawrence, D.A.2
Chuntharapai, A.3
Schow, P.4
Kim, K.J.5
Ashkenazi, A.6
-
32
-
-
0034682802
-
FADD is required for DR4- and DR5-mediated apoptosis: Lack of trail-induced apoptosis in FADD-deficient mouse embryonic fibroblasts
-
Kuang AA, Diehl GE, Zhang J, Winoto A. FADD is required for DR4- and DR5-mediated apoptosis: lack of trail-induced apoptosis in FADD-deficient mouse embryonic fibroblasts. J Biol Chem 2000: 275: 25065-8.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 25065-25068
-
-
Kuang, A.A.1
Diehl, G.E.2
Zhang, J.3
Winoto, A.4
-
33
-
-
0035824635
-
Death receptor recruitment of endogenous caspase-and apoptosis initiation in the absence of caspase-8 1
-
Kischkel FC, Lawrence DA, Tinel A, LeBlanc H, Virmani A, Schow P, et al. Death receptor recruitment of endogenous caspase-and apoptosis initiation in the absence of caspase-8 1. J Biol Chem 2001; 276: 46639-46.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 46639-46646
-
-
Kischkel, F.C.1
Lawrence, D.A.2
Tinel, A.3
LeBlanc, H.4
Virmani, A.5
Schow, P.6
-
34
-
-
0036598992
-
Targeting death and decoy receptors of the tumour-necrosis factor superfamily
-
Ashkenazi A. Targeting death and decoy receptors of the tumour-necrosis factor superfamily. Nat Rev Cancer 2002; 2: 420-30.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 420-430
-
-
Ashkenazi, A.1
-
35
-
-
0034616946
-
Apoptotic pathways: Paper wraps stone blunts scissors
-
Green DR. Apoptotic pathways: paper wraps stone blunts scissors. Cell 2000; 102(1): 1-4.
-
(2000)
Cell
, vol.102
, Issue.1
, pp. 1-4
-
-
Green, D.R.1
-
36
-
-
0035823157
-
Apoptosis. Till death us do part
-
Hunt A, Evan G. Apoptosis. Till death us do part. Science 2001; 293: 1784-5.
-
(2001)
Science
, vol.293
, pp. 1784-1785
-
-
Hunt, A.1
Evan, G.2
-
37
-
-
0032555716
-
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
-
Luo X, Budihardjo I, Zou H, Slaughter C, Wang X. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 1998; 94: 481-90.
-
(1998)
Cell
, vol.94
, pp. 481-490
-
-
Luo, X.1
Budihardjo, I.2
Zou, H.3
Slaughter, C.4
Wang, X.5
-
39
-
-
0035283079
-
Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3
-
Wieder T, Essmann F, Prokop A, Schmelz K, Schulze-Osthoff K, Beyaert R, et al. Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3. Blood 2001; 97(5): 1378-87.
-
(2001)
Blood
, vol.97
, Issue.5
, pp. 1378-1387
-
-
Wieder, T.1
Essmann, F.2
Prokop, A.3
Schmelz, K.4
Schulze-Osthoff, K.5
Beyaert, R.6
-
41
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
Du C, Fang M, Li Y, Li L, Wang X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 2000; 102: 33-42.
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
Fang, M.2
Li, Y.3
Li, L.4
Wang, X.5
-
42
-
-
0034616942
-
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonising IAP proteins
-
Verhagen AM, Ekert PG, Pakusch M, Silke J, Connolly LM, Reid GE, et al. Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonising IAP proteins. Cell 2000; 102: 43-53.
-
(2000)
Cell
, vol.102
, pp. 43-53
-
-
Verhagen, A.M.1
Ekert, P.G.2
Pakusch, M.3
Silke, J.4
Connolly, L.M.5
Reid, G.E.6
-
43
-
-
0032489353
-
TRUNDD, a new member of the TRAIL receptor family that antagonizes TRAIL signalling
-
Pan G, Ni J, Yu G, Wei YF, Dixit VM. TRUNDD, a new member of the TRAIL receptor family that antagonizes TRAIL signalling. FEBS Lett 1998; 424: 41-5.
-
(1998)
FEBS Lett.
, vol.424
, pp. 41-45
-
-
Pan, G.1
Ni, J.2
Yu, G.3
Wei, Y.F.4
Dixit, V.M.5
-
44
-
-
0034776231
-
TRAIL-induced eradication of primary tumour cells from multiple myeloma patient bone marrows is not related to TRAIL receptor expression or prior chemotherapy 1
-
Lincz LF, Yeh TX, Spencer A. TRAIL-induced eradication of primary tumour cells from multiple myeloma patient bone marrows is not related to TRAIL receptor expression or prior chemotherapy 1. Leukaemia 2001; 15: 1650-1657.
-
(2001)
Leukaemia
, vol.15
, pp. 1650-1657
-
-
Lincz, L.F.1
Yeh, T.X.2
Spencer, A.3
-
45
-
-
0000005230
-
Differential localization and regulation of death and decoy receptors for TNF-related apoptosis-inducing ligand (TRAIL) in human melanoma cells
-
Zhang XD, Franco AV, Nguyen T, Gray CP, Hersey P. Differential localization and regulation of death and decoy receptors for TNF-related apoptosis-inducing ligand (TRAIL) in human melanoma cells. J Immunol 2000; 164: 3961-70.
-
(2000)
J. Immunol.
, vol.164
, pp. 3961-3970
-
-
Zhang, X.D.1
Franco, A.V.2
Nguyen, T.3
Gray, C.P.4
Hersey, P.5
-
47
-
-
0035192884
-
FLICE-inhibitory proteins: Regulators of death receptor-mediated apoptosis
-
Krueger A, Baumann S, Krammer PH, Kirchhoff S. FLICE-inhibitory proteins: regulators of death receptor-mediated apoptosis. Mol Cell Biol 2001; 21: 8247-54.
-
(2001)
Mol. Cell Biol.
, vol.21
, pp. 8247-8254
-
-
Krueger, A.1
Baumann, S.2
Krammer, P.H.3
Kirchhoff, S.4
-
48
-
-
0030800070
-
Inhibition of death receptor signals by cellular FLIP 1
-
Irmler M, Thome M, Hahne M, Schneider P, Hofmann K, Steiner V, et al. Inhibition of death receptor signals by cellular FLIP 1. Nature 1997; 388: 190-5.
-
(1997)
Nature
, vol.388
, pp. 190-195
-
-
Irmler, M.1
Thome, M.2
Hahne, M.3
Schneider, P.4
Hofmann, K.5
Steiner, V.6
-
49
-
-
0033989612
-
Inhibition of Fas-mediated apoptosis by the B cell antigen receptor through c-FLIP
-
Wang J, Lobito AA, Shen F, Hornung F, Winoto A, Lenardo MJ. Inhibition of Fas-mediated apoptosis by the B cell antigen receptor through c-FLIP. Eur J Immunol 2000; 30: 155-63.
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 155-163
-
-
Wang, J.1
Lobito, A.A.2
Shen, F.3
Hornung, F.4
Winoto, A.5
Lenardo, M.J.6
-
50
-
-
0037099678
-
c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis
-
Chang DW, Xing Z, Pan Y, Algeciras-Schimnich A, Barnhart BC, Yaish-Ohad S, et al. c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis. EMBO J 2002; 21: 3704-14.
-
(2002)
EMBO J.
, vol.21
, pp. 3704-3714
-
-
Chang, D.W.1
Xing, Z.2
Pan, Y.3
Algeciras-Schimnich, A.4
Barnhart, B.C.5
Yaish-Ohad, S.6
-
51
-
-
0037160117
-
The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex
-
Micheau O, Thome M, Schneider P, Holler N, Tschopp J, Nicholson DW, et al. The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex. J Biol Chem 2002; 277: 45162-71.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 45162-45171
-
-
Micheau, O.1
Thome, M.2
Schneider, P.3
Holler, N.4
Tschopp, J.5
Nicholson, D.W.6
-
52
-
-
0035851189
-
Identification of inhibitors of TRAIL-induced death (ITIDs) in the TRAIL-sensitive colon carcinoma cell line SW4using a genetic approach 1
-
Burns TF, el Deiry WS. Identification of inhibitors of TRAIL-induced death (ITIDs) in the TRAIL-sensitive colon carcinoma cell line SW4using a genetic approach 1. J Biol Chem 2001; 276: 37879-886.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 37879-37886
-
-
Burns, T.F.1
el Deiry, W.S.2
-
53
-
-
0036131142
-
Tumour-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax
-
LeBlanc H, Lawrence D, Varfolomeev E, Totpal K, Morlan J, Schow P, et al. Tumour-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax. Nat Med 2002; 8: 274-81.
-
(2002)
Nat. Med.
, vol.8
, pp. 274-281
-
-
LeBlanc, H.1
Lawrence, D.2
Varfolomeev, E.3
Totpal, K.4
Morlan, J.5
Schow, P.6
-
54
-
-
0037085935
-
Requirement of BAX for TRAIL/Apo2L-induced apoptosis of colorectal cancers: Synergism with sulindac-mediated inhibition of Bcl-x(L)
-
Ravi R, Bedi A. Requirement of BAX for TRAIL/Apo2L-induced apoptosis of colorectal cancers: synergism with sulindac-mediated inhibition of Bcl-x(L). Cancer Res 2002; 62: 1583-7.
-
(2002)
Cancer Res.
, vol.62
, pp. 1583-1587
-
-
Ravi, R.1
Bedi, A.2
-
55
-
-
0036141029
-
TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO 1
-
Deng Y, Lin Y, Wu X. TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO 1. Genes Dev 2002; 16: 33-45.
-
(2002)
Genes Dev.
, vol.16
, pp. 33-45
-
-
Deng, Y.1
Lin, Y.2
Wu, X.3
-
57
-
-
0030698127
-
The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases
-
Roy N, Deveraux QL, Takahashi R, Salvesen GS, Reed JC. The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases. EMBO J 1997; 16: 6914-25.
-
(1997)
EMBO J.
, vol.16
, pp. 6914-6925
-
-
Roy, N.1
Deveraux, Q.L.2
Takahashi, R.3
Salvesen, G.S.4
Reed, J.C.5
-
58
-
-
0036565885
-
Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative-(BMS 247550) and Apo-2L/TRAIL-induced apoptosis
-
Guo F, Nimmanapalli R, Paranawithana S, Wittman S, Griffin D, Bali P, et al. Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative-(BMS 247550) and Apo-2L/TRAIL-induced apoptosis. Blood 2002; 99: 3419-26.
-
(2002)
Blood
, vol.99
, pp. 3419-3426
-
-
Guo, F.1
Nimmanapalli, R.2
Paranawithana, S.3
Wittman, S.4
Griffin, D.5
Bali, P.6
-
59
-
-
0035926316
-
Involvement of TRAIL/TRAIL-R interaction in IFN-alpha-induced apoptosis of Daudi B lymphoma cells
-
Oshima K, Yanase N, Ibukiyama C, Yamashina A, Kayagaki N, Yagita H, et al. Involvement of TRAIL/TRAIL-R interaction in IFN-alpha-induced apoptosis of Daudi B lymphoma cells. Cytokine 2001; 14: 193-201.
-
(2001)
Cytokine
, vol.14
, pp. 193-201
-
-
Oshima, K.1
Yanase, N.2
Ibukiyama, C.3
Yamashina, A.4
Kayagaki, N.5
Yagita, H.6
-
60
-
-
0034968602
-
Theiler's murine encephalomyelitis virus induces apoptosis in gamma interferon-activated M1 differentiated myelomonocytic cells through a mechanism involving tumour necrosis factor alpha (TNF-alpha) and TNF-alpha-related apoptosis-inducing ligand
-
Jelachich ML, Lipton HL. Theiler's murine encephalomyelitis virus induces apoptosis in gamma interferon-activated M1 differentiated myelomonocytic cells through a mechanism involving tumour necrosis factor alpha (TNF-alpha) and TNF-alpha-related apoptosis-inducing ligand. J Virol 2001; 75: 5930-8.
-
(2001)
J. Virol.
, vol.75
, pp. 5930-5938
-
-
Jelachich, M.L.1
Lipton, H.L.2
-
61
-
-
0035879751
-
IFN-gamma induces cell death in human hepatoma cells through a TRAIL/death receptor-mediated apoptotic pathway
-
Shin EC, Ahn JM, Kim CH, Choi Y, Ahn YS, Kim H, et al. IFN-gamma induces cell death in human hepatoma cells through a TRAIL/death receptor-mediated apoptotic pathway. Int J Cancer 2001; 93: 262-8.
-
(2001)
Int. J. Cancer
, vol.93
, pp. 262-268
-
-
Shin, E.C.1
Ahn, J.M.2
Kim, C.H.3
Choi, Y.4
Ahn, Y.S.5
Kim, H.6
-
62
-
-
84889271499
-
IFNgamma sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway
-
Fulda S, Debatin KM. IFNgamma sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway. Oncogene 2002b; 21: 2295-308.
-
(2002)
Oncogene
, vol.21
, pp. 2295-2308
-
-
Fulda, S.1
Debatin, K.M.2
-
63
-
-
0035947569
-
Interferon-gamma sensitizes human myeloid leukaemia cells to death receptor-mediated apoptosis by a pleiotropic mechanism
-
Varela N, Munoz-Pinedo C, Ruiz-Ruiz C, Robledo G, Pedroso M, Lopez-Rivas A. Interferon-gamma sensitizes human myeloid leukaemia cells to death receptor-mediated apoptosis by a pleiotropic mechanism. J Biol Chem 2001; 276: 17779-87.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 17779-17787
-
-
Varela, N.1
Munoz-Pinedo, C.2
Ruiz-Ruiz, C.3
Robledo, G.4
Pedroso, M.5
Lopez-Rivas, A.6
-
65
-
-
0034517764
-
Cleavage of eukaryotic translation initiation factor 4GII correlates with translation inhibition during apoptosis
-
Marissen WE, Gradi A, Sonenberg N, Lloyd RE. Cleavage of eukaryotic translation initiation factor 4GII correlates with translation inhibition during apoptosis. Cell Death Differ 2000; 7: 1234-43.
-
(2000)
Cell Death Differ.
, vol.7
, pp. 1234-1243
-
-
Marissen, W.E.1
Gradi, A.2
Sonenberg, N.3
Lloyd, R.E.4
-
66
-
-
0031899816
-
Auto phosphorylation in the activation loop is required for full kinase activity in vivo of human and yeast eukaryotic initiation factor 2alpha kinases PKR and GCN2
-
Romano PR, Garcia-Barrio MT, Zhang X, Wang Q, Taylor DR, Zhang F, et al. Auto phosphorylation in the activation loop is required for full kinase activity in vivo of human and yeast eukaryotic initiation factor 2alpha kinases PKR and GCN2. Mol Cell Biol 1998; 18: 2282-97.
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 2282-2297
-
-
Romano, P.R.1
Garcia-Barrio, M.T.2
Zhang, X.3
Wang, Q.4
Taylor, D.R.5
Zhang, F.6
-
67
-
-
0029981093
-
An essential role for the interferon-inducible, double-stranded RNA-activated protein kinase PKR in the tumour necrosis factor-induced apoptosis in U9cells
-
Yeung MC, Liu J, Lau AS. An essential role for the interferon-inducible, double-stranded RNA-activated protein kinase PKR in the tumour necrosis factor-induced apoptosis in U9cells. Proc Natl Acad Sci USA 1996; 93: 12451-5.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 12451-12455
-
-
Yeung, M.C.1
Liu, J.2
Lau, A.S.3
-
68
-
-
0033230617
-
PKR; a sentinel kinase for cellular stress
-
Williams BR. PKR; a sentinel kinase for cellular stress. Oncogene 1999; 18: 6112-20.
-
(1999)
Oncogene
, vol.18
, pp. 6112-6120
-
-
Williams, B.R.1
-
69
-
-
0037048685
-
Caspase 9 activation by the dsRNA-dependent protein kinase, PKR: Molecular mechanism and relevance
-
Gil J, Garcia MA, Esteban M. Caspase 9 activation by the dsRNA-dependent protein kinase, PKR: molecular mechanism and relevance. FEBS Lett 2002; 529: 249-55.
-
(2002)
FEBS Lett.
, vol.529
, pp. 249-255
-
-
Gil, J.1
Garcia, M.A.2
Esteban, M.3
-
70
-
-
0035881864
-
FANCC interacts with Hspto protect hematopoietic cells from IFN-gamma/TNF-alpha-mediated cytotoxicity
-
Pang Q, Keeble W, Christianson TA, Faulkner GR, Bagby GC. FANCC interacts with Hspto protect hematopoietic cells from IFN-gamma/TNF-alpha-mediated cytotoxicity. EMBO J 2001; 20: 4478-89.
-
(2001)
EMBO J.
, vol.20
, pp. 4478-4489
-
-
Pang, Q.1
Keeble, W.2
Christianson, T.A.3
Faulkner, G.R.4
Bagby, G.C.5
-
71
-
-
0035869495
-
Role of double-stranded RNA-dependent protein kinase in mediating hypersensitivity of Fanconi anemia complementation group C cells to interferon gamma, tumour necrosis factor-alpha, and double-stranded RNA
-
Pang Q, Keeble W, Diaz J, Christianson TA, Fagerlie S, Rathbun K, et al. Role of double-stranded RNA-dependent protein kinase in mediating hypersensitivity of Fanconi anemia complementation group C cells to interferon gamma, tumour necrosis factor-alpha, and double-stranded RNA. Blood 2001; 97: 1644-52.
-
(2001)
Blood
, vol.97
, pp. 1644-1652
-
-
Pang, Q.1
Keeble, W.2
Diaz, J.3
Christianson, T.A.4
Fagerlie, S.5
Rathbun, K.6
-
72
-
-
17444449609
-
Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: Role of IRF-1 and NF-kappaB
-
Kumar A, Yang YL, Flati V, Der S, Kadereit S, Deb A, et al. Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappaB. EMBO J 1997; 16: 406-16.
-
(1997)
EMBO J.
, vol.16
, pp. 406-416
-
-
Kumar, A.1
Yang, Y.L.2
Flati, V.3
Der, S.4
Kadereit, S.5
Deb, A.6
-
73
-
-
0032936285
-
Double-stranded-RNA-activated protein kinase PKR enhances transcriptional activation by tumour suppressor p1
-
Cuddihy AR, Li S, Tam NW, Wong AH, Taya Y, Abraham N, et al. Double-stranded-RNA-activated protein kinase PKR enhances transcriptional activation by tumour suppressor p1. Mol Cell Biol 1999a, 19: 2475-84.
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 2475-2484
-
-
Cuddihy, A.R.1
Li, S.2
Tam, N.W.3
Wong, A.H.4
Taya, Y.5
Abraham, N.6
-
74
-
-
0033614407
-
The double-stranded RNA activated protein kinase PKR physically associates with the tumour suppressor pprotein and phosphorylates human pon serine 3in vitro
-
Cuddihy AR, Wong AH, Tam NW, Li S, Koromilas AE. The double-stranded RNA activated protein kinase PKR physically associates with the tumour suppressor pprotein and phosphorylates human pon serine 3in vitro. Oncogene 1999b; 18: 2690-2702.
-
(1999)
Oncogene
, vol.18
, pp. 2690-2702
-
-
Cuddihy, A.R.1
Wong, A.H.2
Tam, N.W.3
Li, S.4
Koromilas, A.E.5
-
75
-
-
0037089549
-
Inhibition of protein synthesis in apoptosis: Differential requirements by the tumour necrosis factor alpha family and a DNA-damaging agent for caspases and the double-stranded RNA-dependent protein kinase
-
Jeffrey IW, Bushell M, Tilleray VJ, Morley S, Clemens MJ. Inhibition of protein synthesis in apoptosis: differential requirements by the tumour necrosis factor alpha family and a DNA-damaging agent for caspases and the double-stranded RNA-dependent protein kinase. Cancer Res 2002; 62: 2272-80.
-
(2002)
Cancer Res.
, vol.62
, pp. 2272-2280
-
-
Jeffrey, I.W.1
Bushell, M.2
Tilleray, V.J.3
Morley, S.4
Clemens, M.J.5
-
76
-
-
0030817251
-
Interferon action and apoptosis are defective in mice devoid of 2′, 5′-oligoadenylate-dependent RNase L
-
Zhou A, Paranjape J, Brown TL, Nie H, Naik S, Dong B, et al. Interferon action and apoptosis are defective in mice devoid of 2′, 5′-oligoadenylate-dependent RNase L. EMBO J 1997; 16: 6355-63.
-
(1997)
EMBO J.
, vol.16
, pp. 6355-6363
-
-
Zhou, A.1
Paranjape, J.2
Brown, T.L.3
Nie, H.4
Naik, S.5
Dong, B.6
-
77
-
-
0030924144
-
A study of the interferon antiviral mechanism: Apoptosis activation by the 2-5A system
-
Castelli JC, Hassel BA, Wood KA, Li XL, Amemiya K, Dalakas MC, et al. A study of the interferon antiviral mechanism: apoptosis activation by the 2-5A system. J Exp Med 1997; 186: 967-72.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 967-972
-
-
Castelli, J.C.1
Hassel, B.A.2
Wood, K.A.3
Li, X.L.4
Amemiya, K.5
Dalakas, M.C.6
-
78
-
-
0031870271
-
The role of 2′-5′ oligoadenylate-activated ribonuclease L in apoptosis
-
Castelli JC, Hassel BA, Maran A, Paranjape JM, Hewitt JA, Li XL, et al. The role of 2′-5′ oligoadenylate-activated ribonuclease L in apoptosis. Cell Death Differ 1998; 5: 313-20.
-
(1998)
Cell Death Differ.
, vol.5
, pp. 313-320
-
-
Castelli, J.C.1
Hassel, B.A.2
Maran, A.3
Paranjape, J.M.4
Hewitt, J.A.5
Li, X.L.6
-
79
-
-
0034532259
-
Caspase-dependent apoptosis by 2′-5′-oligoadenylate activation of RNase enhanced by IFN-beta
-
Rusch L, Zhou A, Silverman RH. Caspase-dependent apoptosis by 2′-5′-oligoadenylate activation of RNase enhanced by IFN-beta. J Interferon Cytokine Res 2000; 20: 1091-100.
-
(2000)
J. Interferon Cytokine Res.
, vol.20
, pp. 1091-1100
-
-
Rusch, L.1
Zhou, A.2
Silverman, R.H.3
-
80
-
-
0037047285
-
Identification of X-linked inhibitor of apoptosis-associated factor-1 as an interferon-stimulated gene that augments TRAIL Apo2L-induced apoptosis
-
Leaman DW, Chawla-Sarkar M, Vyas K, Reheman M, Tamai K, Toji S, et al. Identification of X-linked inhibitor of apoptosis-associated factor-1 as an interferon-stimulated gene that augments TRAIL Apo2L-induced apoptosis. J Biol Chem 2002, 277: 28504-11
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 28504-28511
-
-
Leaman, D.W.1
Chawla-Sarkar, M.2
Vyas, K.3
Reheman, M.4
Tamai, K.5
Toji, S.6
-
81
-
-
0036291234
-
IFN-gamma inhibition of TRAIL-induced IAP-2 upregulation, a possible mechanism of IFN-gamma-enhanced TRAIL-induced apoptosis
-
Park SY, Billiar TR, Seol DW. IFN-gamma inhibition of TRAIL-induced IAP-2 upregulation, a possible mechanism of IFN-gamma-enhanced TRAIL-induced apoptosis. Biochem Biophys Res Commun 2002; 291: 233-6.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.291
, pp. 233-236
-
-
Park, S.Y.1
Billiar, T.R.2
Seol, D.W.3
-
82
-
-
0036684548
-
Mitochondria-dependent and - independent mechanisms in tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis are both regulated by interferon-gamma in human breast tumour cells
-
Ruiz-Ruiz C, Lopez-Rivas A. Mitochondria-dependent and - independent mechanisms in tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis are both regulated by interferon-gamma in human breast tumour cells. Biochem J 2002; 365: 825-32.
-
(2002)
Biochem. J.
, vol.365
, pp. 825-832
-
-
Ruiz-Ruiz, C.1
Lopez-Rivas, A.2
-
83
-
-
0034667357
-
Interferon-gamma treatment elevates caspase-8 expression and sensitizes human breast tumour cells to a death receptor-induced mitochondria-operated apoptotic program
-
Ruiz-Ruiz C, Munoz-Pinedo C, Lopez-Rivas A. Interferon-gamma treatment elevates caspase-8 expression and sensitizes human breast tumour cells to a death receptor-induced mitochondria-operated apoptotic program. Cancer Res 2000; 60: 5673-80.
-
(2000)
Cancer Res.
, vol.60
, pp. 5673-5680
-
-
Ruiz-Ruiz, C.1
Munoz-Pinedo, C.2
Lopez-Rivas, A.3
-
84
-
-
0036344715
-
Reduced expression of the inhibitor of apoptosis proteins in T cells from patients with multiple sclerosis following interferon-beta therapy
-
Sharief MK, Noori MA, Zoukos Y. Reduced expression of the inhibitor of apoptosis proteins in T cells from patients with multiple sclerosis following interferon-beta therapy. J Neuroimmunol 2002; 129: 224-31.
-
(2002)
J. Neuroimmunol.
, vol.129
, pp. 224-231
-
-
Sharief, M.K.1
Noori, M.A.2
Zoukos, Y.3
-
85
-
-
0032877019
-
The role of STATs in proliferation, differentiation, and apoptosis
-
Mui AL. The role of STATs in proliferation, differentiation, and apoptosis. Cell Mol Life Sci 1999; 55: 1547-1558.
-
(1999)
Cell Mol. Life Sci.
, vol.55
, pp. 1547-1558
-
-
Mui, A.L.1
-
86
-
-
0032130972
-
The role of interferon regulatory factors in the interferon system and cell growth control
-
Harada H, Taniguchi T, Tanaka N. The role of interferon regulatory factors in the interferon system and cell growth control. Biochimie 1998; 80: 641-650.
-
(1998)
Biochimie
, vol.80
, pp. 641-650
-
-
Harada, H.1
Taniguchi, T.2
Tanaka, N.3
-
87
-
-
0033821215
-
The death domain kinase RIP is essential for TRAIL (Apo2L)-induced activation of IkappaB kinase and c-Jun N-terminal kinase
-
Lin Y, Devin A, Cook A, Keane MM, Kelliher M, Lipkowitz S, et al. The death domain kinase RIP is essential for TRAIL (Apo2L)-induced activation of IkappaB kinase and c-Jun N-terminal kinase. Mol Cell Biol 2000: 6638-45.
-
(2000)
Mol. Cell Biol.
, pp. 6638-6645
-
-
Lin, Y.1
Devin, A.2
Cook, A.3
Keane, M.M.4
Kelliher, M.5
Lipkowitz, S.6
-
88
-
-
0032508414
-
NF-kappaB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
-
Wang CY, Mayo MW, Korneluk RG, Goeddel DV, Baldwin AS, Jr. NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science 1998; 281: 1680-3.
-
(1998)
Science
, vol.281
, pp. 1680-1683
-
-
Wang, C.Y.1
Mayo, M.W.2
Korneluk, R.G.3
Goeddel, D.V.4
Baldwin Jr., A.S.5
-
89
-
-
0033621956
-
The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L)
-
Chen C, Edelstein LC, Gelinas C. The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L). Mol Cell Biol 2000; 20: 2687-95.
-
(2000)
Mol. Cell Biol.
, vol.20
, pp. 2687-2695
-
-
Chen, C.1
Edelstein, L.C.2
Gelinas, C.3
-
90
-
-
0035920230
-
Rel/NF-kappaB transcription factors protect against tumour necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by up-regulating the TRAIL decoy receptor DcR1
-
Bernard D, Quatannens B, Vandenbunder B, Abbadie C. Rel/NF-kappaB transcription factors protect against tumour necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by up-regulating the TRAIL decoy receptor DcR1. J Biol Chem 2001; 276: 27322-8.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 27322-27328
-
-
Bernard, D.1
Quatannens, B.2
Vandenbunder, B.3
Abbadie, C.4
-
91
-
-
0035883162
-
Disruption of NF-kappaB signalling reveals a novel role for NF-kappaB in the regulation of TNF-related apoptosis-inducing ligand expression
-
Baetu TM, Know H, Sharma S, Grandvaux N, Hiscott J. Disruption of NF-kappaB signalling reveals a novel role for NF-kappaB in the regulation of TNF-related apoptosis-inducing ligand expression. J Immunol 2001; 167: 3164-73.
-
(2001)
J. Immunol.
, vol.167
, pp. 3164-3173
-
-
Baetu, T.M.1
Know, H.2
Sharma, S.3
Grandvaux, N.4
Hiscott, J.5
-
92
-
-
0036792643
-
Tumour necrosis factor-related apoptosis inducing ligand (TRAIL) up-regulates death receptor 5 (DR5) mediated by NFkappaB activation in epithelial derived cell lines
-
Shetty S, Gladden JB, Henson ES, Hu X, Villanueva J, Haney N, et al. Tumour necrosis factor-related apoptosis inducing ligand (TRAIL) up-regulates death receptor 5 (DR5) mediated by NFkappaB activation in epithelial derived cell lines. Apoptosis 2002; 7: 413-20.
-
(2002)
Apoptosis
, vol.7
, pp. 413-420
-
-
Shetty, S.1
Gladden, J.B.2
Henson, E.S.3
Hu, X.4
Villanueva, J.5
Haney, N.6
-
93
-
-
0034327721
-
IFN-alpha suppresses activation of nuclear transcription factors NF-kappa B and activator protein 1 and potentiates TNF-induced apoptosis
-
Manna SK, Mukhopadhyay A, Aggarwal BB. IFN-alpha suppresses activation of nuclear transcription factors NF-kappa B and activator protein 1 and potentiates TNF-induced apoptosis. J Immunol 2000; 165: 4927-34.
-
(2000)
J. Immunol.
, vol.165
, pp. 4927-4934
-
-
Manna, S.K.1
Mukhopadhyay, A.2
Aggarwal, B.B.3
-
94
-
-
0035918171
-
Interferon gamma (IFNgamma) and tumour necrosis factor alpha synergism in ME-1cervical cancer cell apoptosis and necrosis. IFNgamma inhibits cytoprotective NF-kappa B through STAT1/IRF-l pathways
-
Suk K, Chang I, Kim YH, Kim S, Kim JY, Kim H, et al. Interferon gamma (IFNgamma) and tumour necrosis factor alpha synergism in ME-1cervical cancer cell apoptosis and necrosis. IFNgamma inhibits cytoprotective NF-kappa B through STAT1/IRF-l pathways. J Biol Chem 2001a; 276: 13153-9.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 13153-13159
-
-
Suk, K.1
Chang, I.2
Kim, Y.H.3
Kim, S.4
Kim, J.Y.5
Kim, H.6
-
95
-
-
0035917314
-
IFNalpha sensitizes ME-1human cervical cancer cells to TNFalpha-induced apoptosis by inhibiting cytoprotective NF-kappaB activation
-
Suk K, Kim YH, Chang I, Kim JY, Choi YH, Lee KY, et al. IFNalpha sensitizes ME-1human cervical cancer cells to TNFalpha-induced apoptosis by inhibiting cytoprotective NF-kappaB activation. FEBS Lett 2001b; 495: 66-70.
-
(2001)
FEBS Lett.
, vol.495
, pp. 66-70
-
-
Suk, K.1
Kim, Y.H.2
Chang, I.3
Kim, J.Y.4
Choi, Y.H.5
Lee, K.Y.6
-
96
-
-
0037457017
-
Interferon-alpha sensitizes human hepatoma cells to TRAIL-induced apoptosis through DR5 upregulation and NF-kappa B inactivation
-
Shigeno M, Nakao K, Ichikawa T, Suzuki K, Kawakami A, Abiru S, et al. Interferon-alpha sensitizes human hepatoma cells to TRAIL-induced apoptosis through DR5 upregulation and NF-kappa B inactivation. Oncogene 2003; 22: 1653-62.
-
(2003)
Oncogene
, vol.22
, pp. 1653-1662
-
-
Shigeno, M.1
Nakao, K.2
Ichikawa, T.3
Suzuki, K.4
Kawakami, A.5
Abiru, S.6
-
97
-
-
0033565590
-
IFN-gamma mediates a novel antiviral activity through dynamic modulation of TRAIL and TRAIL receptor expression
-
Sedger LM, Shows DM, Blanton RA, Peschon JJ, Goodwin RG, Cosman D, et al. IFN-gamma mediates a novel antiviral activity through dynamic modulation of TRAIL and TRAIL receptor expression. J Immunol 1999; 163: 920-6.
-
(1999)
J. Immunol.
, vol.163
, pp. 920-926
-
-
Sedger, L.M.1
Shows, D.M.2
Blanton, R.A.3
Peschon, J.J.4
Goodwin, R.G.5
Cosman, D.6
-
98
-
-
0242414715
-
Protein kinase C modulates tumour necrosis factor-related apoptosis-inducing ligand-induced apoptosis by targeting the apical events of death receptor signaling
-
Harper N, Hughes MA, Farrow SN, Cohen GM, MacFarlane M. Protein kinase C modulates tumour necrosis factor-related apoptosis-inducing ligand-induced apoptosis by targeting the apical events of death receptor signaling. J Biol Chem 2003; 278: 44338-47,
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 44338-44347
-
-
Harper, N.1
Hughes, M.A.2
Farrow, S.N.3
Cohen, G.M.4
MacFarlane, M.5
-
99
-
-
0041333929
-
PG490-mediated sensitization of lung cancer cells to Apo2L/TRAIL-induced apoptosis requires activation of ERK2 1
-
Frese S, Pirnia F, Miescher D, Krajewski S, Borner MM, Reed JC, et al. PG490-mediated sensitization of lung cancer cells to Apo2L/TRAIL-induced apoptosis requires activation of ERK2 1. Oncogene 2003; 22: 5427-35.
-
(2003)
Oncogene
, vol.22
, pp. 5427-5435
-
-
Frese, S.1
Pirnia, F.2
Miescher, D.3
Krajewski, S.4
Borner, M.M.5
Reed, J.C.6
-
100
-
-
0035914394
-
Pro-survival function of Akt/protein kinase B in prostate cancer cells. Relationship with TRAIL resistance 1
-
Thakkar H, Chen X, Tyan F, Gim S, Robinson H, Lee C, et al. Pro-survival function of Akt/protein kinase B in prostate cancer cells. Relationship with TRAIL resistance 1. J Biol Chem 2001; 276: 38361-38369.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 38361-38369
-
-
Thakkar, H.1
Chen, X.2
Tyan, F.3
Gim, S.4
Robinson, H.5
Lee, C.6
-
101
-
-
0037033005
-
FOXO proteins regulate tumour necrosis factor-related apoptosis inducing ligand expression. Implications for PTEN mutation in prostate cancer
-
Modur V, Nagarajan R, Evers BM, Milbrandt J. FOXO proteins regulate tumour necrosis factor-related apoptosis inducing ligand expression. Implications for PTEN mutation in prostate cancer. J Biol Chem 2002; 277: 47928-37.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 47928-47937
-
-
Modur, V.1
Nagarajan, R.2
Evers, B.M.3
Milbrandt, J.4
-
102
-
-
0041589407
-
Identification of interleukin 8 as an inhibitor of tumour necrosis factor-related apoptosis-inducing ligand-induced apoptosis in the ovarian carcinoma cell line OVCAR3
-
Abdollahi T, Robertson NM, Abdollahi A, Litwack G. Identification of interleukin 8 as an inhibitor of tumour necrosis factor-related apoptosis-inducing ligand-induced apoptosis in the ovarian carcinoma cell line OVCAR3. Cancer Res 2003; 63: 4521-6.
-
(2003)
Cancer Res.
, vol.63
, pp. 4521-4526
-
-
Abdollahi, T.1
Robertson, N.M.2
Abdollahi, A.3
Litwack, G.4
-
103
-
-
0034736062
-
Genomic organization and transcriptional regulation of human Apo2/TRAIL gene
-
Gong B, Almasan A. Genomic organization and transcriptional regulation of human Apo2/TRAIL gene. Biochem Biophys Res Commun 2000a; 278: 747-52.
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.278
, pp. 747-752
-
-
Gong, B.1
Almasan, A.2
-
104
-
-
0037790592
-
Apoptosis and interferons: Role of interferon-stimulated genes as mediators of apoptosis 1
-
Chawla-Sarkar M, Lindner DJ, Liu YF, Williams BR, Sen GC, Silverman RH, et al. Apoptosis and interferons: role of interferon-stimulated genes as mediators of apoptosis 1. Apoptosis 2003; 8: 237-49.
-
(2003)
Apoptosis
, vol.8
, pp. 237-249
-
-
Chawla-Sarkar, M.1
Lindner, D.J.2
Liu, Y.F.3
Williams, B.R.4
Sen, G.C.5
Silverman, R.H.6
-
105
-
-
0035496921
-
Apo2L/TRAIL and Bcl-2-related proteins regulate type I interferon-induced apoptosis in multiple myeloma
-
Chen Q, Gong B, Mahmoud-Ahmed AS, Zhou A, Hsi ED, Hussein M, et al. Apo2L/TRAIL and Bcl-2-related proteins regulate type I interferon-induced apoptosis in multiple myeloma. Blood 2001; 98: 2183-92.
-
(2001)
Blood
, vol.98
, pp. 2183-2192
-
-
Chen, Q.1
Gong, B.2
Mahmoud-Ahmed, A.S.3
Zhou, A.4
Hsi, E.D.5
Hussein, M.6
-
106
-
-
0034667482
-
Apo2 ligand/TNF-related apoptosis-inducing ligand and death receptor 5 mediate the apoptotic signaling induced by ionising radiation in leukemic cells
-
Gong B, Almasan A. Apo2 ligand/TNF-related apoptosis-inducing ligand and death receptor 5 mediate the apoptotic signaling induced by ionising radiation in leukemic cells. Cancer Res 2000b; 60: 5754-60.
-
(2000)
Cancer Res.
, vol.60
, pp. 5754-5760
-
-
Gong, B.1
Almasan, A.2
-
107
-
-
0034895641
-
Preferential induction of apoptosis by interferon (IFN)-beta compared with IFN-alpha2: Correlation with TRAIL/Apo2L induction in melanoma cell lines
-
Chawla-Sarkar M, Leaman DW, Borden EC. Preferential induction of apoptosis by interferon (IFN)-beta compared with IFN-alpha2: correlation with TRAIL/Apo2L induction in melanoma cell lines. Clin Cancer Res 2001; 7: 1821-31.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 1821-1831
-
-
Chawla-Sarkar, M.1
Leaman, D.W.2
Borden, E.C.3
-
108
-
-
85047699544
-
Inositol hexakisphosphate kinase 2 sensitizes ovarian carcinoma cells to multiple cancer therapeutics
-
Morrison BH, Bauer JA, Hu J, Grane RW, Ozdemir AM, Chawla-Sarkar M, et al. Inositol hexakisphosphate kinase 2 sensitizes ovarian carcinoma cells to multiple cancer therapeutics. Oncogene 2002; 21: 1882-9.
-
(2002)
Oncogene
, vol.21
, pp. 1882-1889
-
-
Morrison, B.H.1
Bauer, J.A.2
Hu, J.3
Grane, R.W.4
Ozdemir, A.M.5
Chawla-Sarkar, M.6
-
109
-
-
0032443904
-
Apoptosis and growth inhibition of squamous carcinoma cells treated with interferon-alpha, IFN-beta and retinoic acid are associated with induction of the cyclin-dependent kinase inhibitor p21
-
Giandomenico V, Vaccari G, Fiorucci G, Percario ZA, Vannucchi S, Matarrese P, et al. Apoptosis and growth inhibition of squamous carcinoma cells treated with interferon-alpha, IFN-beta and retinoic acid are associated with induction of the cyclin-dependent kinase inhibitor p21. Eur Cytokine Netw 1998; 9: 619-31.
-
(1998)
Eur. Cytokine Netw.
, vol.9
, pp. 619-631
-
-
Giandomenico, V.1
Vaccari, G.2
Fiorucci, G.3
Percario, Z.A.4
Vannucchi, S.5
Matarrese, P.6
-
110
-
-
0037100434
-
IFN-beta pretreatment sensitizes human melanoma cells to TRAIL/Apo2 ligand-induced apoptosis
-
Chawla-Sarkar M, Leaman DW, Jacobs BS, Borden EC. IFN-beta pretreatment sensitizes human melanoma cells to TRAIL/Apo2 ligand-induced apoptosis. J Immunol 2002; 169: 847-55.
-
(2002)
J. Immunol.
, vol.169
, pp. 847-855
-
-
Chawla-Sarkar, M.1
Leaman, D.W.2
Jacobs, B.S.3
Borden, E.C.4
-
111
-
-
0034995408
-
CD40 ligand (CD154) and tumour necrosis factor-related apoptosis inducing ligand (Apo-2L) in haematological malignancies
-
Fiumara P, Younes A. CD40 ligand (CD154) and tumour necrosis factor-related apoptosis inducing ligand (Apo-2L) in haematological malignancies. Br J Haematol 2001; 113: 265-74.
-
(2001)
Br. J. Haematol.
, vol.113
, pp. 265-274
-
-
Fiumara, P.1
Younes, A.2
-
112
-
-
0033583433
-
Monocyte-mediated tumouricidal activity via the tumour necrosis factor-related cytokine, TRAIL
-
Griffith TS, Wiley SR, Kubin MZ, Sedger LM, Maliszewski CR, Fanger NA. Monocyte-mediated tumouricidal activity via the tumour necrosis factor-related cytokine, TRAIL. J Exp Med 1999; 189: 1343-4.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1343-1344
-
-
Griffith, T.S.1
Wiley, S.R.2
Kubin, M.Z.3
Sedger, L.M.4
Maliszewski, C.R.5
Fanger, N.A.6
-
113
-
-
0032701696
-
Human dendritic cells mediate cellular apoptosis via tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)
-
Fanger NA, Maliszewski CR, Schooley K, Griffith TS. Human dendritic cells mediate cellular apoptosis via tumour necrosis factor-related apoptosis-inducing ligand (TRAIL). J Exp Med 1999; 190: 1155-64.
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1155-6114
-
-
Fanger, N.A.1
Maliszewski, C.R.2
Schooley, K.3
Griffith, T.S.4
-
114
-
-
0242509835
-
Regulation of soluble and surface-bound TRAIL in human T cells, B cells, and monocytes
-
Ehrlich S, Infante-Duarte C, Seeger B, Zipp F. Regulation of soluble and surface-bound TRAIL in human T cells, B cells, and monocytes. Cytokine 2003; 24: 244-53.
-
(2003)
Cytokine
, vol.24
, pp. 244-253
-
-
Ehrlich, S.1
Infante-Duarte, C.2
Seeger, B.3
Zipp, F.4
-
115
-
-
0034599757
-
Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) is an inhibitor of autoimmune inflammation and cell cycle progression
-
Song K, Chen Y, Goke R, Wilmen A, Seidel C, Goke A, et al. Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) is an inhibitor of autoimmune inflammation and cell cycle progression. J Exp Med 2000; 191: 1095-104.
-
(2000)
J. Exp. Med.
, vol.191
, pp. 1095-1104
-
-
Song, K.1
Chen, Y.2
Goke, R.3
Wilmen, A.4
Seidel, C.5
Goke, A.6
-
116
-
-
0035863835
-
Roles of TNF-related apoptosis-inducing ligand in experimental autoimmune encephalomyelitis
-
Hilliard B, Wilmen A, Seidel C, Liu TS, Goke R, Chen Y. Roles of TNF-related apoptosis-inducing ligand in experimental autoimmune encephalomyelitis. J Immunol 2001; 166: 1314-9.
-
(2001)
J. Immunol.
, vol.166
, pp. 1314-1319
-
-
Hilliard, B.1
Wilmen, A.2
Seidel, C.3
Liu, T.S.4
Goke, R.5
Chen, Y.6
-
117
-
-
0037338951
-
Defective thymocyte apoptosis and accelerated autoimmune diseases in TRAIL-/- mice 1
-
Lamhamedi-Cherradi SE, Zheng SJ, Maguschak KA, Peschon J, Chen YH. Defective thymocyte apoptosis and accelerated autoimmune diseases in TRAIL-/- mice 1. Nat Immunol 2003; 4: 255-60.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 255-260
-
-
Lamhamedi-Cherradi, S.E.1
Zheng, S.J.2
Maguschak, K.A.3
Peschon, J.4
Chen, Y.H.5
-
118
-
-
0037094010
-
Death ligand TRAIL induces no apoptosis but inhibits activation of human (auto)antigen-specific T cells
-
Lunemann JD, Waiczies S, Ehrlich S, Wendling U, Seeger B, Kamradt T, et al. Death ligand TRAIL induces no apoptosis but inhibits activation of human (auto)antigen-specific T cells. J Immunol 2002; 168: 4881-8.
-
(2002)
J. Immunol.
, vol.168
, pp. 4881-4888
-
-
Lunemann, J.D.1
Waiczies, S.2
Ehrlich, S.3
Wendling, U.4
Seeger, B.5
Kamradt, T.6
-
119
-
-
0031719383
-
Involvement of APO2 ligand/TRAIL in activation-induced death of Jurkat and human peripheral blood T cells
-
Martinez-Lorenzo MJ, Alava MA, Gamen S, Kim KJ, Chuntharapai A, Pineiro A, et al. Involvement of APO2 ligand/TRAIL in activation-induced death of Jurkat and human peripheral blood T cells. Eur J Immunol 1998; 28: 2714-25.
-
(1998)
Eur. J. Immunol.
, vol.28
, pp. 2714-2725
-
-
Martinez-Lorenzo, M.J.1
Alava, M.A.2
Gamen, S.3
Kim, K.J.4
Chuntharapai, A.5
Pineiro, A.6
-
120
-
-
9844225051
-
Activity of TNF-related apoptosis-inducing ligand (TRAIL) in haematological malignancies
-
Snell V, Clodi K, Zhao S, Goodwin R, Thomas EK, Morris SW, et al. Activity of TNF-related apoptosis-inducing ligand (TRAIL) in haematological malignancies. Br J Haematol 1997; 99: 618-24.
-
(1997)
Br. J. Haematol.
, vol.99
, pp. 618-624
-
-
Snell, V.1
Clodi, K.2
Zhao, S.3
Goodwin, R.4
Thomas, E.K.5
Morris, S.W.6
-
121
-
-
0034061453
-
Lipopolysaccharide induces expression of APO2 ligand/TRAIL in human monocytes and macrophages
-
Halaas O, Vik R, Ashkenazi A, Espevik T. Lipopolysaccharide induces expression of APO2 ligand/TRAIL in human monocytes and macrophages. Scand J Immunol 2000; 51: 244-50.
-
(2000)
Scand. J. Immunol.
, vol.51
, pp. 244-250
-
-
Halaas, O.1
Vik, R.2
Ashkenazi, A.3
Espevik, T.4
-
122
-
-
0033881830
-
Reovirus-induced apoptosis is mediated by TRAIL
-
Clarke P, Meintzer SM, Gibson S, Widmann C, Garrington TP, Johnson GL, et al. Reovirus-induced apoptosis is mediated by TRAIL. J Virol 2000; 74: 8135-9.
-
(2000)
J. Virol.
, vol.74
, pp. 8135-8139
-
-
Clarke, P.1
Meintzer, S.M.2
Gibson, S.3
Widmann, C.4
Garrington, T.P.5
Johnson, G.L.6
-
123
-
-
0033988563
-
Measles virus induces functional TRAIL production by human dendritic cells
-
Vidalain PO, Azocar O, Lamouille B, Astier A, Rabourdin-Combe C, Servet-Delprat C. Measles virus induces functional TRAIL production by human dendritic cells. J Virol 2000; 74: 556-9.
-
(2000)
J. Virol.
, vol.74
, pp. 556-559
-
-
Vidalain, P.O.1
Azocar, O.2
Lamouille, B.3
Astier, A.4
Rabourdin-Combe, C.5
Servet-Delprat, C.6
-
124
-
-
0034986360
-
Identification of a potential HIV-induced source of bystander-mediated apoptosis in T cells: Upregulation of trail in primary human macrophages by HIV-1 tat
-
Zhang M, Li X, Pang X, Ding L, Wood O, Clouse KHL, et al. Identification of a potential HIV-induced source of bystander-mediated apoptosis in T cells: upregulation of trail in primary human macrophages by HIV-1 tat. J Biomed Sci 2001a; 8: 290-6.
-
(2001)
J. Biomed. Sci.
, vol.8
, pp. 290-296
-
-
Zhang, M.1
Li, X.2
Pang, X.3
Ding, L.4
Wood, O.5
Clouse, K.H.L.6
-
125
-
-
0035798624
-
NF-kappaB Signaling pathway governs TRAIL gene expression and human T-cell leukaemia virus-I Tax-induced T-cell death
-
Rivera-Walsh I, Waterfield M, Xiao G, Fong A, Sun SC. NF-kappaB Signaling pathway governs TRAIL gene expression and human T-cell leukaemia virus-I Tax-induced T-cell death. J Biol Chem 2001; 276: 40385-8.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 40385-40388
-
-
Rivera-Walsh, I.1
Waterfield, M.2
Xiao, G.3
Fong, A.4
Sun, S.C.5
-
126
-
-
0034667997
-
Adenovirus E1A oncogene expression in tumour cells enhances killing by TNF-related apoptosis-inducing ligand (TRAIL)
-
Routes JM, Ryan S, Clase A, Miura T, Kuhl A, Potter TA, et al. Adenovirus E1A oncogene expression in tumour cells enhances killing by TNF-related apoptosis-inducing ligand (TRAIL). J Immunol 2000; 165: 4522-7.
-
(2000)
J. Immunol.
, vol.165
, pp. 4522-4527
-
-
Routes, J.M.1
Ryan, S.2
Clase, A.3
Miura, T.4
Kuhl, A.5
Potter, T.A.6
-
127
-
-
0035933897
-
The cytokines tumour necrosis factor-alpha (TNF-alpha) and TNF-related apoptosis-inducing ligand differentially modulate proliferation and apoptotic pathways in human keratinocytes expressing the human papillomavirus-16 E7 oncoprotein
-
Basile JR, Zacny V, Munger K. The cytokines tumour necrosis factor-alpha (TNF-alpha) and TNF-related apoptosis-inducing ligand differentially modulate proliferation and apoptotic pathways in human keratinocytes expressing the human papillomavirus-16 E7 oncoprotein. J Biol Chem 2001; 276: 22522-8.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 22522-22528
-
-
Basile, J.R.1
Zacny, V.2
Munger, K.3
-
128
-
-
0035179965
-
Antiviral response by natural killer cells through TRAIL gene induction by IFN-alpha/beta
-
Sato K, Hida S, Takayanagi H, Yokochi T, Kayagaki N, Takeda K, et al. Antiviral response by natural killer cells through TRAIL gene induction by IFN-alpha/beta, Eur J Immunol 2001; 31(11): 3138-46.
-
(2001)
Eur. J. Immunol.
, vol.31
, Issue.11
, pp. 3138-3146
-
-
Sato, K.1
Hida, S.2
Takayanagi, H.3
Yokochi, T.4
Kayagaki, N.5
Takeda, K.6
-
129
-
-
0033519303
-
Type I interferons (IFNs) regulate tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) expression on human T cells: A novel mechanism for the antitumour effects of type I IFNs
-
Kayagaki N, Yamaguchi N, Nakayama M, Eto H, Okumura K, Yagita H. Type I interferons (IFNs) regulate tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) expression on human T cells: A novel mechanism for the antitumour effects of type I IFNs. J Exp Med 1999; 189: 1451-60.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1451-1460
-
-
Kayagaki, N.1
Yamaguchi, N.2
Nakayama, M.3
Eto, H.4
Okumura, K.5
Yagita, H.6
-
130
-
-
0032575714
-
Death receptors: Signaling and modulation
-
Ashkenazi A, Dixit VM. Death receptors: signaling and modulation. Science 1998; 281: 1305-8.
-
(1998)
Science
, vol.281
, pp. 1305-1308
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
131
-
-
0032929520
-
Tumouricidal activity of tumour necrosis factor-related apoptosis-inducing ligand in vivo
-
Walczak H, Miller RE, Ariail K, Gliniak B, Griffith TS, Kubin M, et al. Tumouricidal activity of tumour necrosis factor-related apoptosis-inducing ligand in vivo. Nat Med 1999; 5: 157-63.
-
(1999)
Nat. Med.
, vol.5
, pp. 157-163
-
-
Walczak, H.1
Miller, R.E.2
Ariail, K.3
Gliniak, B.4
Griffith, T.S.5
Kubin, M.6
-
132
-
-
0034022160
-
Apoptosis induced in normal human hepatocytes by tumour necrosis factor-related apoptosis-inducing ligand
-
Jo M, Kim TH, Seol DW, Esplen JE, Dorko K, Billiar TR, et al. Apoptosis induced in normal human hepatocytes by tumour necrosis factor-related apoptosis-inducing ligand. Nat Med 2000; 6: 564-7.
-
(2000)
Nat. Med.
, vol.6
, pp. 564-567
-
-
Jo, M.1
Kim, T.H.2
Seol, D.W.3
Esplen, J.E.4
Dorko, K.5
Billiar, T.R.6
-
134
-
-
0033083990
-
Chemotherapy augments TRAIL-induced apoptosis in breast cell lines
-
Keane MM, Ettenberg SA, Nan MM, Russell EK, Lipkowitz S. Chemotherapy augments TRAIL-induced apoptosis in breast cell lines. Cancer Res 1999; 59: 734-41.
-
(1999)
Cancer Res.
, vol.59
, pp. 734-741
-
-
Keane, M.M.1
Ettenberg, S.A.2
Nan, M.M.3
Russell, E.K.4
Lipkowitz, S.5
-
135
-
-
0034747649
-
Enhanced sensitivity of bladder cancer cells to tumour necrosis factor related apoptosis inducing ligand mediated apoptosis by cisplatin and carboplatin
-
Mizutani Y, Nakao M, Ogawa O, Yoshida O, Bonavida B, Miki T. Enhanced sensitivity of bladder cancer cells to tumour necrosis factor related apoptosis inducing ligand mediated apoptosis by cisplatin and carboplatin. J Urol 2001; 165: 263-70.
-
(2001)
J. Urol.
, vol.165
, pp. 263-270
-
-
Mizutani, Y.1
Nakao, M.2
Ogawa, O.3
Yoshida, O.4
Bonavida, B.5
Miki, T.6
-
136
-
-
0034985464
-
Synergistic induction of apoptosis by the combination of trail and chemotherapy in chemoresistant ovarian cancer cells
-
Cuello M, Ettenberg SA, Nan MM, Lipkowitz S. Synergistic induction of apoptosis by the combination of trail and chemotherapy in chemoresistant ovarian cancer cells. Gynecol Oncol 2001; 81: 380-90.
-
(2001)
Gynecol. Oncol.
, vol.81
, pp. 380-390
-
-
Cuello, M.1
Ettenberg, S.A.2
Nan, M.M.3
Lipkowitz, S.4
-
137
-
-
0034652156
-
Combined effect of tumour necrosis factor-related apoptosis-inducing ligand and ionising radiation in breast cancer therapy
-
Chinnaiyan AM, Prasad U, Shankar S, Hamstra DA, Shanaiah M, Chenevert TL, et al. Combined effect of tumour necrosis factor-related apoptosis-inducing ligand and ionising radiation in breast cancer therapy. Proc Natl Acad Sci USA 2000; 97: 1754-9.
-
(2000)
Proc. Natl. Acad. Sci USA
, vol.97
, pp. 1754-1759
-
-
Chinnaiyan, A.M.1
Prasad, U.2
Shankar, S.3
Hamstra, D.A.4
Shanaiah, M.5
Chenevert, T.L.6
-
138
-
-
0033572413
-
Tumour necrosis factor-related apoptosis-inducing ligand's antitumour activity in vivo is enhanced by the chemotherapeutic agent CPT-11
-
Gliniak B, Le T, Tumour necrosis factor-related apoptosis-inducing ligand's antitumour activity in vivo is enhanced by the chemotherapeutic agent CPT-11. Cancer Res 1999; 59: 6153-8.
-
(1999)
Cancer Res.
, vol.59
, pp. 6153-6158
-
-
Gliniak, B.1
Le, T.2
-
139
-
-
0033710429
-
Sensitivity to TRAIL/APO-2L-mediated apoptosis in human renal cell carcinomas and its enhancement by topotecan
-
Dejosez M, Ramp U, Mahotka C, Krieg.A., Walczak H, Gabber HE, et al. Sensitivity to TRAIL/APO-2L-mediated apoptosis in human renal cell carcinomas and its enhancement by topotecan. Cell Death Differ 2000; 7: 1127-36.
-
(2000)
Cell Death Differ.
, vol.7
, pp. 1127-1136
-
-
Dejosez, M.1
Ramp, U.2
Mahotka, C.3
Krieg, A.4
Walczak, H.5
Gabber, H.E.6
-
140
-
-
0033839749
-
Chemotherapeutic agents augment TRAIL-induced apoptosis in human hepatocellular carcinoma cell lines
-
Yamanaka T, Shiraki K, Sugimoto K, Ito T, Fujikawa K, Ito M, et al. Chemotherapeutic agents augment TRAIL-induced apoptosis in human hepatocellular carcinoma cell lines. Hepatology 2000; 32: 482-90.
-
(2000)
Hepatology
, vol.32
, pp. 482-490
-
-
Yamanaka, T.1
Shiraki, K.2
Sugimoto, K.3
Ito, T.4
Fujikawa, K.5
Ito, M.6
-
141
-
-
0034914110
-
Tumour necrosis factor-related apoptosis-inducing ligand and chemotherapy cooperate to induce apoptosis in mesothelioma cell lines 1
-
Liu W, Bodle E, Chen JY, Gao M, Rosen GD, Broaddus VC. Tumour necrosis factor-related apoptosis-inducing ligand and chemotherapy cooperate to induce apoptosis in mesothelioma cell lines 1. Am J Respir Cell Mol Biol 2001; 25: 111-8.
-
(2001)
Am. J. Respir. Cell Mol. Biol.
, vol.25
, pp. 111-118
-
-
Liu, W.1
Bodle, E.2
Chen, J.Y.3
Gao, M.4
Rosen, G.D.5
Broaddus, V.C.6
-
142
-
-
0035866369
-
Anticancer agents sensitize tumour cells to tumour necrosis factor-related apoptosis-inducing ligand-mediated caspase-8 activation and apoptosis
-
Lacour S, Hammann A, Wotawa A, Corcos L, Solary E, Dimanche-Boitrel MT. Anticancer agents sensitize tumour cells to tumour necrosis factor-related apoptosis-inducing ligand-mediated caspase-8 activation and apoptosis. Cancer Res 2001; 61: 1645-51.
-
(2001)
Cancer Res.
, vol.61
, pp. 1645-1651
-
-
Lacour, S.1
Hammann, A.2
Wotawa, A.3
Corcos, L.4
Solary, E.5
Dimanche-Boitrel, M.T.6
-
143
-
-
0034652486
-
Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumour necrosis factor-related apoptosis-inducing ligand in vitro and in vivo
-
Nagane M, Pan G, Weddle JJ, Dixit VM, Cavenee WK, Huang HJ. Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumour necrosis factor-related apoptosis-inducing ligand in vitro and in vivo Cancer Res 2000; 60: 847-53.
-
(2000)
Cancer Res.
, vol.60
, pp. 847-853
-
-
Nagane, M.1
Pan, G.2
Weddle, J.J.3
Dixit, V.M.4
Cavenee, W.K.5
Huang, H.J.6
-
144
-
-
0035001741
-
The potential of TRAIL for cancer chemotherapy
-
Nagane M, Huang HJ, Cavenee WK. The potential of TRAIL for cancer chemotherapy. Apoptosis 2001; 6: 191-7.
-
(2001)
Apoptosis
, vol.6
, pp. 191-197
-
-
Nagane, M.1
Huang, H.J.2
Cavenee, W.K.3
-
145
-
-
0345598868
-
Requirement of p53 targets in chemosensitization of colonic carcinoma to death ligand therapy
-
Wang S, el Deiry WS. Requirement of p53 targets in chemosensitization of colonic carcinoma to death ligand therapy. Proc Natl Acad Sci USA 2003; 100: 15095-100.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 15095-15100
-
-
Wang, S.1
el Deiry, W.S.2
-
146
-
-
0036143575
-
Tumour necrosis factor-related apoptosis-inducing ligand induces caspase-dependent interleukin-8 expression and apoptosis in human astroglioma cells
-
Choi C, Kutsch O, Park J, Zhou T, Seol DW, Benveniste EN. Tumour necrosis factor-related apoptosis-inducing ligand induces caspase-dependent interleukin-8 expression and apoptosis in human astroglioma cells. Mol Cell Biol 2002; 22: 724-36.
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 724-736
-
-
Choi, C.1
Kutsch, O.2
Park, J.3
Zhou, T.4
Seol, D.W.5
Benveniste, E.N.6
-
148
-
-
0035476255
-
Tumour necrosis factor-related apoptosis-inducing ligand-induced apoptosis of human melanoma is regulated by smac/DIABLO release from mitochondria
-
Zhang XD, Zhang XY, Gray CP, Nguyen T, Hersey P. Tumour necrosis factor-related apoptosis-inducing ligand-induced apoptosis of human melanoma is regulated by smac/DIABLO release from mitochondria. Cancer Res 2001b; 61: 7339-48.
-
(2001)
Cancer Res.
, vol.61
, pp. 7339-7348
-
-
Zhang, X.D.1
Zhang, X.Y.2
Gray, C.P.3
Nguyen, T.4
Hersey, P.5
-
149
-
-
1342301477
-
IFNgamma sensitization to TRAIL-induced apoptosis in human thyroid carcinoma cells by upregulating Bak expression
-
Wang SH, Mezosi E, Wolf JM, Cao Z, Utsugi S, Gauger PG, et al. IFNgamma sensitization to TRAIL-induced apoptosis in human thyroid carcinoma cells by upregulating Bak expression. Oncogene 2004; 23: 928-35.
-
(2004)
Oncogene
, vol.23
, pp. 928-935
-
-
Wang, S.H.1
Mezosi, E.2
Wolf, J.M.3
Cao, Z.4
Utsugi, S.5
Gauger, P.G.6
-
150
-
-
0032885416
-
The proteasome inhibitor PS-341 in cancer therapy
-
Teicher BA, Ara G, Herbst R, Palombella VJ, Adams J. The proteasome inhibitor PS-341 in cancer therapy. Clin Cancer Res 1999; 5: 2638-45.
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 2638-2645
-
-
Teicher, B.A.1
Ara, G.2
Herbst, R.3
Palombella, V.J.4
Adams, J.5
-
151
-
-
0043287140
-
The proteasome inhibitor PS-341 overcomes TRAIL resistance in Bax and caspase 9-negative or Bcl-xL overexpressing cells
-
Johnson TR, Stone K, Nikrad M, Yeh T, Zong WX, Thompson CB, et al. The proteasome inhibitor PS-341 overcomes TRAIL resistance in Bax and caspase 9-negative or Bcl-xL overexpressing cells. Oncogene 2003; 22: 4953-63.
-
(2003)
Oncogene
, vol.22
, pp. 4953-4963
-
-
Johnson, T.R.1
Stone, K.2
Nikrad, M.3
Yeh, T.4
Zong, W.X.5
Thompson, C.B.6
-
152
-
-
0036020190
-
Antitumour activity and prolonged expression from a TRAIL-expressing adenoviral vector
-
Lee J, Hampi M, Albert P, Fine HA. Antitumour activity and prolonged expression from a TRAIL-expressing adenoviral vector. Neoplasia 2002; 4: 312-23.
-
(2002)
Neoplasia
, vol.4
, pp. 312-323
-
-
Lee, J.1
Hampi, M.2
Albert, P.3
Fine, H.A.4
-
153
-
-
0036645266
-
Targeted expression of green fluorescent protein/tumour necrosis factor-related apoptosis-inducing ligand fusion protein from human telomerase reverse transcriptase promoter elicits antitumour activity without toxic effects on primary human hepatocytes
-
Lin T, Gu J, Zhang L, Huang X, Stephens LC, Curley SA. et al. Targeted expression of green fluorescent protein/tumour necrosis factor-related apoptosis-inducing ligand fusion protein from human telomerase reverse transcriptase promoter elicits antitumour activity without toxic effects on primary human hepatocytes. Cancer Res 2002; 62: 3620-5.
-
(2002)
Cancer Res.
, vol.62
, pp. 3620-3625
-
-
Lin, T.1
Gu, J.2
Zhang, L.3
Huang, X.4
Stephens, L.C.5
Curley, S.A.6
-
154
-
-
0036167572
-
Resistance of prostate cancer cells to soluble TNF-related apoptosis-inducing ligand (TRAIL/Apo2L) can be overcome by doxorubicin or adenoviral delivery of full-length TRAIL
-
Voelkel-Johnson C, King DL, Norris JS.Resistance of prostate cancer cells to soluble TNF-related apoptosis-inducing ligand (TRAIL/Apo2L) can be overcome by doxorubicin or adenoviral delivery of full-length TRAIL. Cancer Gene Ther 2002; 9: 164-72.
-
(2002)
Cancer Gene Ther.
, vol.9
, pp. 164-172
-
-
Voelkel-Johnson, C.1
King, D.L.2
Norris, J.S.3
-
155
-
-
1542438698
-
Additive effect of TRAIL and p53 gene transfer on apoptosis of human lung cancer cell lines
-
Jang SH, Seol JY, Kim CH, Yoo CG, Kim YW, Han SK, et al. Additive effect of TRAIL and p53 gene transfer on apoptosis of human lung cancer cell lines. Int J Mol Med 2004; 13: 181-6.
-
(2004)
Int. J. Mol. Med.
, vol.13
, pp. 181-186
-
-
Jang, S.H.1
Seol, J.Y.2
Kim, C.H.3
Yoo, C.G.4
Kim, Y.W.5
Han, S.K.6
-
156
-
-
0037507288
-
Adenoviral gene transfer of tumour necrosis factor-related apoptosis-inducing ligand overcomes an impaired response of hepatoma cells but causes severe apoptosis in primary human hepatocytes
-
Armeanu S, Lauer UM, Smirnow I, Schenk M, Weiss TS, Gregor M, et al. Adenoviral gene transfer of tumour necrosis factor-related apoptosis-inducing ligand overcomes an impaired response of hepatoma cells but causes severe apoptosis in primary human hepatocytes. Cancer Res 2003; 63: 2369-72.
-
(2003)
Cancer Res.
, vol.63
, pp. 2369-2372
-
-
Armeanu, S.1
Lauer, U.M.2
Smirnow, I.3
Schenk, M.4
Weiss, T.S.5
Gregor, M.6
-
157
-
-
0037241481
-
Role of type I cytokines in host defense against Mycobacterium avium infection
-
Danelishvilli L, Bermudez LE. Role of type I cytokines in host defense against Mycobacterium avium infection. Curr Pharm Design 2003; 9(1): 61-5.
-
(2003)
Curr. Pharm. Design.
, vol.9
, Issue.1
, pp. 61-65
-
-
Danelishvilli, L.1
Bermudez, L.E.2
-
158
-
-
0037243234
-
Anti-interleukin-6 therapy for Crohn's disease
-
Ito H. Anti-interleukin-6 therapy for Crohn's disease. Curr Pharm Design 2003; 9(4): 295-305.
-
(2003)
Curr. Pharm. Design.
, vol.9
, Issue.4
, pp. 295-305
-
-
Ito, H.1
|