Interferon-α sensitizes human hepatoma cells to TRAIL-induced apoptosis through DR5 upregulation and NF-κB inactivation

Oncogene

Volumn 22, Issue 11, 2003, Pages 1653-1662

  Shigeno, Masaya ^a   Nakao, Kazuhiko ^b   Ichikawa, Tatsuki ^a   Suzuki, Kasumi ^b   Kawakami, Atsushi ^a   Abiru, Seigou ^a   Miyazoe, Seiji ^a   Nakagawa, Yuichi ^a   Ishikawa, Hiroki ^a   Hamasaki, Keisuke ^a   Nakata, Keisuke ^a   Ishii, Nobuko ^b   Eguchi, Katsumi ^a  

^a NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NAGASAKI UNIVERSITY   (Japan)

Author keywords

DR5 survivin; Hepatoma; Interferon ; NF B; TRAIL

Indexed keywords

ALPHA INTERFERON; CASPASE 8; DEATH RECEPTOR 5; DIMER; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN P50; SURVIVIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL FUNCTION; CELL STRAIN HEPG2; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; DRUG SENSITIVITY; ENZYME ACTIVATION; HEPATOMA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BASE SEQUENCE; CARCINOMA, HEPATOCELLULAR; CASPASE 8; CASPASE 9; CASPASES; DNA PRIMERS; DOWN-REGULATION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME ACTIVATION; HUMANS; INTERFERON-ALPHA; LIVER NEOPLASMS; MEMBRANE GLYCOPROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; NF-KAPPA B; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; RECEPTORS, TUMOR NECROSIS FACTOR; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 0037457017     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206139     Document Type: Article

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