Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: Role of IRF-1 and NF-κB

EMBO Journal

Volumn 16, Issue 2, 1997, Pages 406-416

  Kumar, Aseem ^a,b   Yang, Yi Li ^c   Flati, Vincenzo ^a   Der, Sandy ^a   Kadereit, Suzanne ^a   Deb, Amitabha ^a   Haque, Jaharul ^a   Reis, Luiz ^c   Weissmann, Charles ^c   Williams, Bryan R G ^a,b  

^a LERNER RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Cytokine signaling; Interferon; IRF 1; NF B; PKR gene

Indexed keywords

CYTOKINE; DOUBLE STRANDED RNA; GAMMA INTERFERON; GUANINE NUCLEOTIDE BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INITIATION FACTOR 2; INTERFERON; INTERFERON REGULATORY FACTOR 1; PROTEIN SERINE THREONINE KINASE; REGULATOR PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; EMBRYO; EMBRYO CELL; FIBROBLAST; GENE CONSTRUCT; GENE DELETION; GENE DISRUPTION; GENE TARGETING; GENETIC TRANSFECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION; REPORTER GENE; SIGNAL TRANSDUCTION;

ANIMALS; BLOTTING, NORTHERN; CYTOKINES; DNA-BINDING PROTEINS; EIF-2 KINASE; FIBROBLASTS; GENE DELETION; INTERFERON REGULATORY FACTOR-1; INTERFERON TYPE II; MICE; NF-KAPPA B; PHOSPHOPROTEINS; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); PROTEIN-SERINE-THREONINE KINASES; RNA, DOUBLE-STRANDED; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSFECTION;

ANIMALIA;

EID: 17444449609     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.2.406     Document Type: Article

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