-
1
-
-
0022539964
-
Complement membrane attack complex stimulates production of reactive oxygen metabolites by cultured rat mesangial cells
-
Adler S, Baker PJ, Johnson RJ, Ochi RF, Pritzl P, Couser WG (1986) Complement membrane attack complex stimulates production of reactive oxygen metabolites by cultured rat mesangial cells. J Clin Invest 77:762-767
-
(1986)
J. Clin. Invest.
, vol.77
, pp. 762-767
-
-
Adler, S.1
Baker, P.J.2
Johnson, R.J.3
Ochi, R.F.4
Pritzl, P.5
Couser, W.G.6
-
2
-
-
0032905278
-
Fatal familial insomnia: A new Austrian family
-
Almer G, Hainfellner JA, Brücke T, Jellinger K, Kleinert R, Bayer G, Windl O, Kretzschmar HA, Hill A, Sidle K, Collinge J, Budka H (1999) Fatal familial insomnia: A new Austrian family. Brain 122:5-16
-
(1999)
Brain
, vol.122
, pp. 5-16
-
-
Almer, G.1
Hainfellner, J.A.2
Bücke, T.3
Jellinger, K.4
Kleinert, R.5
Bayer, G.6
Windl, O.7
Kretzschmar, H.A.8
Hill, A.9
Sidle, K.10
Collinge, J.11
Budka, H.12
-
3
-
-
0021716145
-
Neurone loss in the nucleus basalis of Meynert in Creutzfeldt-Jakob disease
-
Arendt T, Bigl V, Arendt A (1984) Neurone loss in the nucleus basalis of Meynert in Creutzfeldt-Jakob disease. Acta Neuropathol 65:85-88
-
(1984)
Acta Neuropathol.
, vol.65
, pp. 85-88
-
-
Arendt, T.1
Bigl, V.2
Arendt, A.3
-
4
-
-
0029099103
-
Inactivation of glutathione peroxidase by nitric oxide. Implication for cytotoxicity
-
Asahi M, Fujii J, Suzuki K, Seo HG, Kuzuya T, Hori M, Tada M, Fujii S, Taniguchi N (1995) Inactivation of glutathione peroxidase by nitric oxide. Implication for cytotoxicity. J Biol Chem 270:21035-21039
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 21035-21039
-
-
Asahi, M.1
Fujii, J.2
Suzuki, K.3
Seo, H.G.4
Kuzuya, T.5
Hori, M.6
Tada, M.7
Fujii, S.8
Taniguchi, N.9
-
5
-
-
0034798246
-
Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie
-
Aucouturier P, Geissmann F, Damotte D, Saborio GP, Meeker HC, Kascsak R, Kascsak R, Carp RI, Wisniewski T (2001) Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie. J Clin Invest 108:703-708
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 703-708
-
-
Aucouturier, P.1
Geissmann, F.2
Damotte, D.3
Saborio, G.P.4
Meeker, H.C.5
Kascsak, R.6
Kascsak, R.7
Carp, R.I.8
Wisniewski, T.9
-
6
-
-
0030949946
-
Evidence for an alternative direct route of access for the scrapie agent to the brain bypassing the spinal cord
-
Baldauf E, Beekes M, Diringer H (1997) Evidence for an alternative direct route of access for the scrapie agent to the brain bypassing the spinal cord. J Gen Virol 78:1187-1197
-
(1997)
J. Gen. Virol.
, vol.78
, pp. 1187-1197
-
-
Baldauf, E.1
Beekes, M.2
Diringer, H.3
-
7
-
-
0035828142
-
Killing of prion-damaged neurones by microglia
-
Bate C, Reid S, Williams A (2001) Killing of prion-damaged neurones by microglia. Neuroreport 12:2589-2594
-
(2001)
Neuroreport
, vol.12
, pp. 2589-2594
-
-
Bate, C.1
Reid, S.2
Williams, A.3
-
8
-
-
0031881510
-
Cerebral targeting indicates vagal spread of infection in hamsters fed with scrapie
-
Beekes M, McBride PA, Baldauf E (1998) Cerebral targeting indicates vagal spread of infection in hamsters fed with scrapie. J Gen Virol 79:601-607
-
(1998)
J. Gen. Virol.
, vol.79
, pp. 601-607
-
-
Beekes, M.1
McBride, P.A.2
Baldauf, E.3
-
9
-
-
0032885694
-
Early destruction of the extracellular matrix around parvalbumin-immunoreactive interneurons in Creutzfeldt-Jakob disease
-
Belichenko PV, Miklossy J, Belser B, Budka H, Celio MR (1999) Early destruction of the extracellular matrix around parvalbumin-immunoreactive interneurons in Creutzfeldt-Jakob disease. Neurobiol Dis 6:269-279
-
(1999)
Neurobiol. Dis.
, vol.6
, pp. 269-279
-
-
Belichenko, P.V.1
Miklossy, J.2
Belser, B.3
Budka, H.4
Celio, M.R.5
-
10
-
-
0038186806
-
PrP-expressing tissue required for transfer of scrapie infectivity from spleen to brain
-
Blättler T, Brandner S, Raeber AJ, Klein MA, Voigtländer T, Weissmann C, Aguzzi A (1997) PrP-expressing tissue required for transfer of scrapie infectivity from spleen to brain. Nature 389:69-73
-
(1997)
Nature
, vol.389
, pp. 69-73
-
-
Blättler, T.1
Brandner, S.2
Raeber, A.J.3
Klein, M.A.4
Voigtländer, T.5
Weissmann, C.6
Aguzzi, A.7
-
11
-
-
0030054010
-
Normal host prion protein necessary for scrapie-induced neurotoxicity
-
Brandner S, Isenmann S, Raeber A, Fischer M, Sailer A, Kobayashi Y, Marino S, Weissmann C, Aguzzi A (1996) Normal host prion protein necessary for scrapie-induced neurotoxicity. Nature 379:339-343
-
(1996)
Nature
, vol.379
, pp. 339-343
-
-
Brandner, S.1
Isenmann, S.2
Raeber, A.3
Fischer, M.4
Sailer, A.5
Kobayashi, Y.6
Marino, S.7
Weissmann, C.8
Aguzzi, A.9
-
12
-
-
0041852638
-
Inducible cytokine gene expression in the brain in the ME7/CV mouse model of scrapie is highly restricted, is at a strikingly low level relative to the degree of gliosis and occurs only late in the disease
-
Brown AR, Webb J, Rebus S, Walker R, Williams A, Fazakerley JK (2003) Inducible cytokine gene expression in the brain in the ME7/CV mouse model of scrapie is highly restricted, is at a strikingly low level relative to the degree of gliosis and occurs only late in the disease. J Gen Virol 84:2605-2611
-
(2003)
J. Gen. Virol.
, vol.84
, pp. 2605-2611
-
-
Brown, A.R.1
Webb, J.2
Rebus, S.3
Walker, R.4
Williams, A.5
Fazakerley, J.K.6
-
13
-
-
0032212367
-
Prion protein-overexpressing cells show altered response to a neurotoxic prion protein peptide
-
Brown DR (1998) Prion protein-overexpressing cells show altered response to a neurotoxic prion protein peptide. J Neurosci Res 54:331-340
-
(1998)
J. Neurosci. Res.
, vol.54
, pp. 331-340
-
-
Brown, D.R.1
-
14
-
-
0032817255
-
Prion protein peptide neurotoxicity can be mediated by astrocytes
-
Brown DR (1999) Prion protein peptide neurotoxicity can be mediated by astrocytes. J Neurochem 73:1105-1113
-
(1999)
J. Neurochem.
, vol.73
, pp. 1105-1113
-
-
Brown, D.R.1
-
15
-
-
0034533064
-
Sc-like prion protein peptide inhibits the function of cellular prion protein
-
Sc-like prion protein peptide inhibits the function of cellular prion protein. Biochem J 352:511-518
-
(2000)
Biochem. J.
, vol.352
, pp. 511-518
-
-
Brown, D.R.1
-
16
-
-
0032169565
-
Prion protein expression and superoxide dismutase activity
-
Brown DR, Besinger A (1998) Prion protein expression and superoxide dismutase activity. Biochem J 334:423-429
-
(1998)
Biochem. J.
, vol.334
, pp. 423-429
-
-
Brown, D.R.1
Besinger, A.2
-
17
-
-
0036798415
-
Copper-dependent functions for the prion protein
-
Brown DR, Sassoon J (2002) Copper-dependent functions for the prion protein. Mol Biotechnol 22:165-178
-
(2002)
Mol. Biotechnol.
, vol.22
, pp. 165-178
-
-
Brown, D.R.1
Sassoon, J.2
-
18
-
-
0028143841
-
Mouse cortical cells lacking cellular PrP survive in culture with a neurotoxic PrP fragment
-
Brown DR, Herms J, Kretzschmar HA (1994) Mouse cortical cells lacking cellular PrP survive in culture with a neurotoxic PrP fragment. Neuroreport 5:2057-2060
-
(1994)
Neuroreport
, vol.5
, pp. 2057-2060
-
-
Brown, D.R.1
Herms, J.2
Kretzschmar, H.A.3
-
19
-
-
0029997484
-
Role of microglia and host prion protein in neurotoxicity of a prion protein fragment
-
Brown DR, Schmidt B, Kretzschmar HA (1996) Role of microglia and host prion protein in neurotoxicity of a prion protein fragment. Nature 380:345-347
-
(1996)
Nature
, vol.380
, pp. 345-347
-
-
Brown, D.R.1
Schmidt, B.2
Kretzschmar, H.A.3
-
20
-
-
0031444294
-
The cellular prion protein binds copper in vivo
-
Brown DR, Qin K, Herms JW, Madlung A, Manson J, Strome R, Fraser PE, Kruck T, von Bohlen A, Schulz-Schaeffer W, Giese A, Westaway D, Kretzschmar H (1997) The cellular prion protein binds copper in vivo. Nature 390:684-687
-
(1997)
Nature
, vol.390
, pp. 684-687
-
-
Brown, D.R.1
Qin, K.2
Herms, J.W.3
Madlung, A.4
Manson, J.5
Strome, R.6
Fraser, P.E.7
Kruck, T.8
von Bohlen, A.9
Schulz-Schaeffer, W.10
Giese, A.11
Westaway, D.12
Kretzschmar, H.13
-
21
-
-
18344403931
-
Effects of oxidative stress on prion protein expression in PC12 cells
-
Brown DR, Schmidt B, Kretzschmar HA (1997) Effects of oxidative stress on prion protein expression in PC12 cells. Int J Dev Neurosci 15:961-972
-
(1997)
Int. J. Dev. Neurosci.
, vol.15
, pp. 961-972
-
-
Brown, D.R.1
Schmidt, B.2
Kretzschmar, H.A.3
-
22
-
-
0031194455
-
Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity
-
Brown DR, Schulz-Schaeffer WJ, Schmidt B, Kretzschmar HA (1997) Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity. Exp Neurol 146:104-112
-
(1997)
Exp. Neurol.
, vol.146
, pp. 104-112
-
-
Brown, D.R.1
Schulz-Schaeffer, W.J.2
Schmidt, B.3
Kretzschmar, H.A.4
-
23
-
-
0033571055
-
Normal prion protein has an activity like that of superoxide dismutase
-
Brown DR, Wong BS, Hafiz F, Clive C, Haswell SJ, Jones IM (1999) Normal prion protein has an activity like that of superoxide dismutase. Biochem J 344:1-5
-
(1999)
Biochem. J.
, vol.344
, pp. 1-5
-
-
Brown, D.R.1
Wong, B.S.2
Hafiz, F.3
Clive, C.4
Haswell, S.J.5
Jones, I.M.6
-
24
-
-
0035158321
-
Antioxidant activity related to copper binding of native prion protein
-
Brown DR, Clive C, Haswell SJ (2001) Antioxidant activity related to copper binding of native prion protein. J Neurochem 76:69-76
-
(2001)
J. Neurochem.
, vol.76
, pp. 69-76
-
-
Brown, D.R.1
Clive, C.2
Haswell, S.J.3
-
25
-
-
0037080043
-
Lack of prion protein expression results in a neuronal phenotype sensitive to stress
-
Brown DR, Nicholas RSJ, Canevari L (2002) Lack of prion protein expression results in a neuronal phenotype sensitive to stress. J Neurosci Res 67:211-224
-
(2002)
J. Neurosci. Res.
, vol.67
, pp. 211-224
-
-
Brown, D.R.1
Nicholas, R.S.J.2
Canevari, L.3
-
26
-
-
0032746253
-
Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cells
-
Brown KL, Stewart K, Ritchie DL, Mabbott NA, Williams A, Fraser H, Morrison WI, Bruce ME (1999) Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cells. Nat Med 5:1308-1312
-
(1999)
Nat. Med.
, vol.5
, pp. 1308-1312
-
-
Brown, K.L.1
Stewart, K.2
Ritchie, D.L.3
Mabbott, N.A.4
Williams, A.5
Fraser, H.6
Morrison, W.I.7
Bruce, M.E.8
-
27
-
-
0141515178
-
TSE strain variation
-
Bruce ME (2003) TSE strain variation. Br Med Bull 66:99-108
-
(2003)
Br. Med. Bull.
, vol.66
, pp. 99-108
-
-
Bruce, M.E.1
-
28
-
-
28444470232
-
Histopathology and immunohistochemistry of human transmissible spongiform encephalopathies (TSEs)
-
Budka H (2000) Histopathology and immunohistochemistry of human transmissible spongiform encephalopathies (TSEs). Arch Virol [Suppl] 16:135 142
-
(2000)
Arch. Virol.
, vol.16
, Issue.SUPPL.
, pp. 135-142
-
-
Budka, H.1
-
29
-
-
0141849861
-
Neuropathology of prion diseases
-
Budka H (2003) Neuropathology of prion diseases. Br Med Bull 66:121-130
-
(2003)
Br. Med. Bull.
, vol.66
, pp. 121-130
-
-
Budka, H.1
-
30
-
-
0026600865
-
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
-
Büeler H, Fischer M, Lang Y, Bluethmann H, Lipp HP, DeArmond SJ, Prusiner SB, Aguet M, Weissmann C (1992) Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein. Nature 356:577-582
-
(1992)
Nature
, vol.356
, pp. 577-582
-
-
Büeler, H.1
Fischer, M.2
Lang, Y.3
Bluethmann, H.4
Lipp, H.P.5
DeArmond, S.J.6
Prusiner, S.B.7
Aguet, M.8
Weissmann, C.9
-
31
-
-
0027319326
-
Mice devoid of PrP are resistant to scrapie
-
Büeler H, Aguzzi A, Sailer A, Greiner RA, Autenried P, Aguet M, Weissmann C (1993) Mice devoid of PrP are resistant to scrapie. Cell 73:1339-1347
-
(1993)
Cell
, vol.73
, pp. 1339-1347
-
-
Büeler, H.1
Aguzzi, A.2
Sailer, A.3
Greiner, R.A.4
Autenried, P.5
Aguet, M.6
Weissmann, C.7
-
32
-
-
0028535880
-
High prion and PrPSc levels but delayed onset of disease in scrapie-inoculated mice heterozygous for a disrupted PrP gene
-
Büeler H, Raeber A, Sailer A, Fischer M, Aguzzi A, Weissmann C (1994) High prion and PrPSc levels but delayed onset of disease in scrapie-inoculated mice heterozygous for a disrupted PrP gene. Mol Med 1:19-30
-
(1994)
Mol. Med.
, vol.1
, pp. 19-30
-
-
Büeler, H.1
Raeber, A.2
Sailer, A.3
Fischer, M.4
Aguzzi, A.5
Weissmann, C.6
-
33
-
-
0033386245
-
Poly(ADP-ribose) immunostaining to detect apoptosis induced by a neurotoxic fragment of prion protein
-
Bürkle A, Kretzschmar HA, Brown DR (1999) Poly(ADP-ribose) immunostaining to detect apoptosis induced by a neurotoxic fragment of prion protein. Histochem J 31:711-716
-
(1999)
Histochem. J.
, vol.31
, pp. 711-716
-
-
Bürkle, A.1
Kretzschmar, H.A.2
Brown, D.R.3
-
35
-
-
0031710192
-
Mitochondrial dysfunction induced by oxidative stress in the brains of hamsters infected with the 263 K scrapie agent
-
Choi SI, Ju WK, Choi EK, Kim J, Lea HZ, Carp RI, Wisniewski HM, Kim YS (1998) Mitochondrial dysfunction induced by oxidative stress in the brains of hamsters infected with the 263 K scrapie agent. Acta Neuropathol 96:279-286
-
(1998)
Acta Neuropathol.
, vol.96
, pp. 279-286
-
-
Choi, S.I.1
Ju, W.K.2
Choi, E.K.3
Kim, J.4
Lea, H.Z.5
Carp, R.I.6
Wisniewski, H.M.7
Kim, Y.S.8
-
36
-
-
2342477648
-
Fibrillar prion peptide (106-126) and scrapie prion protein hamper phagocytosis in microglia
-
Ciesielski-Treska J, Grant NJ, Ulrich G, Corrotte M, Bailly Y, Haeberle AM, Chasserot-Golaz S, Bader MF (2004) Fibrillar prion peptide (106-126) and scrapie prion protein hamper phagocytosis in microglia. Glia 46:101-115
-
(2004)
Glia
, vol.46
, pp. 101-115
-
-
Ciesielski-Treska, J.1
Grant, N.J.2
Ulrich, G.3
Corrotte, M.4
Bailly, Y.5
Haeberle, A.M.6
Chasserot-Golaz, S.7
Bader, M.F.8
-
37
-
-
0021212843
-
Pathogenesis of mouse scrapie: Distribution of agent in the pulp and stroma of infected spleens
-
Clarke MC, Kimberlin RH (1984) Pathogenesis of mouse scrapie: distribution of agent in the pulp and stroma of infected spleens. Vet Microbiol 9:215-225
-
(1984)
Vet. Microbiol.
, vol.9
, pp. 215-225
-
-
Clarke, M.C.1
Kimberlin, R.H.2
-
38
-
-
0026788002
-
Key morphological features of apoptosis may occur in the absence of internucleosomal DNA fragmentation
-
Cohen GM, Sun XM, Snowden RT, Dinsdale D, Skilleter DN (1992) Key morphological features of apoptosis may occur in the absence of internucleosomal DNA fragmentation. Biochem J 286:331-334
-
(1992)
Biochem. J.
, vol.286
, pp. 331-334
-
-
Cohen, G.M.1
Sun, X.M.2
Snowden, R.T.3
Dinsdale, D.4
Skilleter, D.N.5
-
39
-
-
0021808813
-
Pathogenesis of mouse scrapie: Dynamics of vacuolation in brain and spinal cord after intraperitoneal infection
-
Cole S, Kimberlin RH (1985) Pathogenesis of mouse scrapie: Dynamics of vacuolation in brain and spinal cord after intraperitoneal infection. Neuropathol Appl Neurobiol 11:213-227
-
(1985)
Neuropathol. Appl. Neurobiol.
, vol.11
, pp. 213-227
-
-
Cole, S.1
Kimberlin, R.H.2
-
40
-
-
0033838528
-
Complement activation after oxidative stress. Role of the lectin complement pathway
-
Collard CD, Väkevä A, Morrissey MA, Agah A, Rollins SA, Reenstra WR, Buras JA, Meri S, Stahl GL (2000) Complement activation after oxidative stress. Role of the lectin complement pathway. Am J Pathol 156:1549-1556
-
(2000)
Am. J. Pathol.
, vol.156
, pp. 1549-1556
-
-
Collard, C.D.1
Väkevä, A.2
Morrissey, M.A.3
Agah, A.4
Rollins, S.A.5
Reenstra, W.R.6
Buras, J.A.7
Meri, S.8
Stahl, G.L.9
-
41
-
-
0027997387
-
Prion protein is necessary for normal synaptic function
-
Collinge J, Whittington MA, Sidle KCL, Smith CJ, Palmer MS, Clarke AR, Jefferys JGR (1994) Prion protein is necessary for normal synaptic function. Nature 370:295-297
-
(1994)
Nature
, vol.370
, pp. 295-297
-
-
Collinge, J.1
Whittington, M.A.2
Sidle, K.C.L.3
Smith, C.J.4
Palmer, M.S.5
Clarke, A.R.6
Jefferys, J.G.R.7
-
42
-
-
0026731894
-
Interleukin 3 protects murine bone marrow cells from apoptosis induced by DNA damaging agents
-
Collins MK, Marvel J, Malde P, Lopez-Rivas A (1992) Interleukin 3 protects murine bone marrow cells from apoptosis induced by DNA damaging agents. J Exp Med 176:1043-1051
-
(1992)
J. Exp. Med.
, vol.176
, pp. 1043-1051
-
-
Collins, M.K.1
Marvel, J.2
Malde, P.3
Lopez-Rivas, A.4
-
43
-
-
10744228678
-
Prion protein fragment 106-126 induces a p38 MAP kinase-dependent apoptosis in SH-SY5Y neuroblastoma cells independently from the amyloid fibril formation
-
Corsaro A, Thellung S, Villa V, Principe DR, Paludi D, Arena S, Millo E, Schettini D, Damonte G, Aceto A, Schettini G, Florio T (2003) Prion protein fragment 106-126 induces a p38 MAP kinase-dependent apoptosis in SH-SY5Y neuroblastoma cells independently from the amyloid fibril formation. Ann N Y Acad Sci 1010:610-622
-
(2003)
Ann. N Y Acad. Sci.
, vol.1010
, pp. 610-622
-
-
Corsaro, A.1
Thellung, S.2
Villa, V.3
Principe, D.R.4
Paludi, D.5
Arena, S.6
Millo, E.7
Schettini, D.8
Damonte, G.9
Aceto, A.10
Schettini, G.11
Florio, T.12
-
44
-
-
0036230262
-
Transforming growth factor β1, the dominant cytokine in murine prion disease: Influence on inflammatory cytokine synthesis and alteration of vascular extracellular matrix
-
Cunningham C, Boche D, Perry VH (2002) Transforming growth factor β1, the dominant cytokine in murine prion disease: Influence on inflammatory cytokine synthesis and alteration of vascular extracellular matrix. Neuropathol Appl Neurobiol 28:107-119
-
(2002)
Neuropathol. Appl. Neurobiol.
, vol.28
, pp. 107-119
-
-
Cunningham, C.1
Boche, D.2
Perry, V.H.3
-
45
-
-
0038809966
-
Synaptic changes characterize early behavioural signs in the ME7 model of murine prion disease
-
Cunningham C, Deacon R, Wells H, Boche D, Waters S, Picanco Diniz C, Scott H, Rawlins JNP, Perry VH (2003) Synaptic changes characterize early behavioural signs in the ME7 model of murine prion disease. Eur J Neurosci 17:2147-2155
-
(2003)
Eur. J. Neurosci.
, vol.17
, pp. 2147-2155
-
-
Cunningham, C.1
Deacon, R.2
Wells, H.3
Boche, D.4
Waters, S.5
Picanco Diniz, C.6
Scott, H.7
Rawlins, J.N.P.8
Perry, V.H.9
-
46
-
-
7144251862
-
Neuronal apoptosis in fatal familial insomnia
-
Dorandeu A, Wingertsmann L, Chrétien F, Delisle MB, Vital C, Parchi P, Montagna P, Lugaresi E, Ironside JW, Budka H, Gambetti P, Gray F (1998) Neuronal apoptosis in fatal familial insomnia. Brain Pathol 8:531-537
-
(1998)
Brain Pathol.
, vol.8
, pp. 531-537
-
-
Dorandeu, A.1
Wingertsmann, L.2
Chrétien, F.3
Delisle, M.B.4
Vital, C.5
Parchi, P.6
Montagna, P.7
Lugaresi, E.8
Ironside, J.W.9
Budka, H.10
Gambetti, P.11
Gray, F.12
-
47
-
-
0028330051
-
C3a activates reactive oxygen radical species production and intracellular calcium transients in human eosinophils
-
Elsner J, Oppermann M, Czech W, Dobos G, Schöpf E, Norgauer J, Kapp A (1994) C3a activates reactive oxygen radical species production and intracellular calcium transients in human eosinophils. Eur J Immunol 24:518-522
-
(1994)
Eur. J. Immunol.
, vol.24
, pp. 518-522
-
-
Elsner, J.1
Oppermann, M.2
Czech, W.3
Dobos, G.4
Schöpf, E.5
Norgauer, J.6
Kapp, A.7
-
48
-
-
0033521542
-
Mature follicular dendritic cell networks depend on expression of lymphotoxin beta receptor by radioresistant stromal cells and of lymphotoxin beta and tumor necrosis factor by B cells
-
Endres R, Alimzhanov MB, Plitz T, Futterer A, Kosco-Vilbois MH, Nedospasov SA, Rajewsky K, Pfeffer K (1999) Mature follicular dendritic cell networks depend on expression of lymphotoxin beta receptor by radioresistant stromal cells and of lymphotoxin beta and tumor necrosis factor by B cells. J Exp Med 189:159-168
-
(1999)
J. Exp. Med.
, vol.189
, pp. 159-168
-
-
Endres, R.1
Alimzhanov, M.B.2
Plitz, T.3
Futterer, A.4
Kosco-Vilbois, M.H.5
Nedospasov, S.A.6
Rajewsky, K.7
Pfeffer, K.8
-
49
-
-
0027276494
-
The protein kinase inhibitor staurosporine induces morphological changes typical of apoptosis in MOLT-4 cells without concomitant DNA fragmentation
-
Falcieri E, Martelli AM, Bareggi R, Cataldi A, Cocco L (1993) The protein kinase inhibitor staurosporine induces morphological changes typical of apoptosis in MOLT-4 cells without concomitant DNA fragmentation. Biochem Biophys Res Commun 193:19-25
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.193
, pp. 19-25
-
-
Falcieri, E.1
Martelli, A.M.2
Bareggi, R.3
Cataldi, A.4
Cocco, L.5
-
50
-
-
0033002350
-
Nuclear DNA fragmentation in Creutzfeldt-Jakob disease: Does a mere positive in situ nuclear end-labeling indicate apoptosis?
-
Ferrer I (1999) Nuclear DNA fragmentation in Creutzfeldt-Jakob disease: does a mere positive in situ nuclear end-labeling indicate apoptosis? Acta Neuropathol 97:5-12
-
(1999)
Acta Neuropathol.
, vol.97
, pp. 5-12
-
-
Ferrer, I.1
-
51
-
-
0027483615
-
Neurotoxicity of a prion protein fragment
-
Forloni G, Angeretti N, Chiesa R, Monzani E, Salmona M, Bugiani O, Tagliavini F (1993) Neurotoxicity of a prion protein fragment. Nature 362:543-546
-
(1993)
Nature
, vol.362
, pp. 543-546
-
-
Forloni, G.1
Angeretti, N.2
Chiesa, R.3
Monzani, E.4
Salmona, M.5
Bugiani, O.6
Tagliavini, F.7
-
52
-
-
0027768576
-
Demonstration of extensive chromatin cleavage in transplanted Morris hepatoma 7777 tissue: Apoptosis or necrosis?
-
1:CAS:528:DyaK3sXkvFanu78%3D
-
K, Kojiro M, Chiu JF (1993) Demonstration of extensive chromatin cleavage in transplanted Morris hepatoma 7777 tissue: Apoptosis or necrosis? Am J Pathol 142:935-946 1:CAS:528:DyaK3sXkvFanu78%3D
-
(1993)
Am. J. Pathol.
, vol.142
, pp. 935-946
-
-
Fukuda, K.1
Kojiro, M.2
Chiu, J.F.3
-
53
-
-
0033921540
-
Complement components of the innate immune system in health and disease in the CNS
-
Gasque P, Dean YD, McGreal EP, VanBeek J, Morgan BP (2000) Complement components of the innate immune system in health and disease in the CNS. Immunopharmacology 49:171-186
-
(2000)
Immunopharmacology
, vol.49
, pp. 171-186
-
-
Gasque, P.1
Dean, Y.D.2
McGreal, E.P.3
VanBeek, J.4
Morgan, B.P.5
-
54
-
-
0026648674
-
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
-
10.1083/jcb.119.3.493
-
Gavrieli Y, Sherman Y, Ben-Sasson SA (1992) Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 119:493-501 10.1083/jcb.119.3.493
-
(1992)
J Cell Biol
, vol.119
, pp. 493-501
-
-
Gavrieli, Y.1
Sherman, Y.2
Ben-Sasson, S.A.3
-
55
-
-
0029085515
-
Neuronal cell death in scrapie-infected mice is due to apoptosis
-
1:STN:280:BymD2cfhsFU%3D
-
Giese A, Groschup MH, Hess B, Kretzschmar HA (1995) Neuronal cell death in scrapie-infected mice is due to apoptosis. Brain Pathol 5:213-221 1:STN:280:BymD2cfhsFU%3D
-
(1995)
Brain Pathol.
, vol.5
, pp. 213-221
-
-
Giese, A.1
Groschup, M.H.2
Hess, B.3
Kretzschmar, H.A.4
-
56
-
-
0031803512
-
Role of microglia in neuronal cell death in prion disease
-
1:CAS:528:DyaK1cXksFCmtr4%3D
-
Giese A, Brown DR, Groschup MH, Feldmann C, Haist I, Kretzschmar HA (1998) Role of microglia in neuronal cell death in prion disease. Brain Pathol 8:449-457 1:CAS:528:DyaK1cXksFCmtr4%3D
-
(1998)
Brain Pathol.
, vol.8
, pp. 449-457
-
-
Giese, A.1
Brown, D.R.2
Groschup, M.H.3
Feldmann, C.4
Haist, I.5
Kretzschmar, H.A.6
-
57
-
-
0035013510
-
Prion-induced neuronal damage-the mechanisms of neuronal destruction in the subacute spongiform encephalopathies
-
1:CAS:528:DC%2BD3MXks1agt74%3D
-
Giese A, Kretzschmar HA (2001) Prion-induced neuronal damage-the mechanisms of neuronal destruction in the subacute spongiform encephalopathies. Curr Top Microbiol Immunol 253:203-217 1:CAS:528:DC%2BD3MXks1agt74%3D
-
(2001)
Curr. Top. Microbiol. Immunol.
, vol.253
, pp. 203-217
-
-
Giese, A.1
Kretzschmar, H.A.2
-
58
-
-
0034891027
-
Sympathetic innervation of lymphoreticular organs is rate limiting for prion neuroinvasion
-
10.1016/S0896-6273(01)00331-2
-
Glatzel M, Heppner FL, Albers KM, Aguzzi A (2001) Sympathetic innervation of lymphoreticular organs is rate limiting for prion neuroinvasion. Neuron 31:25-34 10.1016/S0896-6273(01)00331-2
-
(2001)
Neuron
, vol.31
, pp. 25-34
-
-
Glatzel, M.1
Heppner, F.L.2
Albers, K.M.3
Aguzzi, A.4
-
59
-
-
0032489912
-
The sequential role of lymphotoxin and B cells in the development of splenic follicles
-
10.1084/jem.187.7.997
-
Gonzalez M, Mackay F, Browning JL, Kosco-Vilbois MH, Noelle RJ (1998) The sequential role of lymphotoxin and B cells in the development of splenic follicles. J Exp Med 187:997-1007 10.1084/jem.187.7.997
-
(1998)
J. Exp. Med.
, vol.187
, pp. 997-1007
-
-
Gonzalez, M.1
Mackay, F.2
Browning, J.L.3
Kosco-Vilbois, M.H.4
Noelle, R.J.5
-
60
-
-
0345654322
-
Neuronal apoptosis in Creutzfeldt-Jakob disease
-
1:STN:280:DyaK1M3jt12qtw%3D%3D
-
Gray F, Chretien F, Adle-Biassette H, Dorandeu A, Ereau T, Delisle MB, Kopp N, Ironside JW, Vital C (1999) Neuronal apoptosis in Creutzfeldt-Jakob disease. J Neuropathol Exp Neurol 58:321-328 1:STN:280:DyaK1M3jt12qtw%3D%3D
-
(1999)
J. Neuropathol. Exp. Neurol.
, vol.58
, pp. 321-328
-
-
Gray, F.1
Chretien, F.2
Adle-Biassette, H.3
Dorandeu, A.4
Ereau, T.5
Delisle, M.B.6
Kopp, N.7
Ironside, J.W.8
Vital, C.9
-
61
-
-
0030929562
-
Distribution of parvalbumin-immunoreactive neurons in brain correlates with hippocampal and temporal cortical pathology in Creutzfeldt-Jakob disease
-
1:CAS:528:DyaK2sXmvVyrsr4%3D
-
Guentchev M, Hainfellner JA, Trabattoni GR, Budka H (1997) Distribution of parvalbumin-immunoreactive neurons in brain correlates with hippocampal and temporal cortical pathology in Creutzfeldt-Jakob disease. J Neuropathol Exp Neurol 56:1119-1124 1:CAS:528:DyaK2sXmvVyrsr4%3D
-
(1997)
J. Neuropathol. Exp. Neurol.
, vol.56
, pp. 1119-1124
-
-
Guentchev, M.1
Hainfellner, J.A.2
Trabattoni, G.R.3
Budka, H.4
-
62
-
-
0031661397
-
Severe, early and selective loss of a subpopulation of GABAergic inhibitory neurons in experimental transmissible spongiform encephalopathies
-
1:CAS:528:DyaK1cXmvF2ju7g%3D
-
Guentchev M, Groschup MH, Kordek R, Liberski PP, Budka H (1998) Severe, early and selective loss of a subpopulation of GABAergic inhibitory neurons in experimental transmissible spongiform encephalopathies. Brain Pathol 8:615-623 1:CAS:528:DyaK1cXmvF2ju7g%3D
-
(1998)
Brain Pathol.
, vol.8
, pp. 615-623
-
-
Guentchev, M.1
Groschup, M.H.2
Kordek, R.3
Liberski, P.P.4
Budka, H.5
-
63
-
-
0032726882
-
Selective neuronal vulnerability in human prion diseases. Fatal familial insomnia differs from other types of prion diseases
-
1:STN:280:DC%2BD3c%2FhvFKgug%3D%3D
-
Guentchev M, Wanschitz J, Voigtländer T, Flicker H, Budka H (1999) Selective neuronal vulnerability in human prion diseases. Fatal familial insomnia differs from other types of prion diseases. Am J Pathol 155:1453-1457 1:STN:280:DC%2BD3c%2FhvFKgug%3D%3D
-
(1999)
Am. J. Pathol.
, vol.155
, pp. 1453-1457
-
-
Guentchev, M.1
Wanschitz, J.2
Voigtländer, T.3
Flicker, H.4
Budka, H.5
-
64
-
-
0033826082
-
Evidence for oxidative stress in experimental prion disease
-
10.1006/nbdi.2000.0290
-
Guentchev M, Voigtländer T, Haberler C, Groschup MH, Budka H (2000) Evidence for oxidative stress in experimental prion disease. Neurobiol Dis 7:270-273 10.1006/nbdi.2000.0290
-
(2000)
Neurobiol. Dis.
, vol.7
, pp. 270-273
-
-
Guentchev, M.1
Voigtländer, T.2
Haberler, C.3
Groschup, M.H.4
Budka, H.5
-
65
-
-
0036236406
-
Oxidative damage to nucleic acids in human prion disease
-
10.1006/nbdi.2002.0477
-
Guentchev M, Siedlak SL, Jarius C, Tagliavini F, Castellani RJ, Perry G, Smith MA, Budka H (2002) Oxidative damage to nucleic acids in human prion disease. Neurobiol Dis 9:275-281 10.1006/nbdi.2002.0477
-
(2002)
Neurobiol. Dis.
, vol.9
, pp. 275-281
-
-
Guentchev, M.1
Siedlak, S.L.2
Jarius, C.3
Tagliavini, F.4
Castellani, R.J.5
Perry, G.6
Smith, M.A.7
Budka, H.8
-
66
-
-
0032828301
-
Disease associated prion protein may deposit in the peripheral nervous system in human transmissible spongiform encephalopathies
-
10.1007/s004010051109
-
Hainfellner JA, Budka H (1999) Disease associated prion protein may deposit in the peripheral nervous system in human transmissible spongiform encephalopathies. Acta Neuropathol 98:458-460 10.1007/ s004010051109
-
(1999)
Acta Neuropathol.
, vol.98
, pp. 458-460
-
-
Hainfellner, J.A.1
Budka, H.2
-
67
-
-
0023098327
-
Biogenesis and transmembrane orientation of the cellular isoform of the scrapie prion protein
-
1:CAS:528:DyaL2sXhtleqs7Y%3D
-
Hay B, Barry RA, Lieberburg I, Prusiner SB, Lingappa VR (1987) Biogenesis and transmembrane orientation of the cellular isoform of the scrapie prion protein. Mol Cell Biol 7:914-920 1:CAS:528:DyaL2sXhtleqs7Y%3D
-
(1987)
Mol. Cell Biol.
, vol.7
, pp. 914-920
-
-
Hay, B.1
Barry, R.A.2
Lieberburg, I.3
Prusiner, S.B.4
Lingappa, V.R.5
-
68
-
-
0023566948
-
Evidence for a secretory form of the cellular prion protein
-
1:CAS:528:DyaL1cXktFej
-
Hay B, Prusiner SB, Lingappa VR (1987) Evidence for a secretory form of the cellular prion protein. Biochemistry 26:8110-8115 1:CAS:528:DyaL1cXktFej
-
(1987)
Biochemistry
, vol.26
, pp. 8110-8115
-
-
Hay, B.1
Prusiner, S.B.2
Lingappa, V.R.3
-
69
-
-
1142267004
-
Peripheral tissue involvement in sporadic, iatrogenic, and variant Creutzfeldt-Jakob disease: An immunohistochemical, quantitative, and biochemical study
-
1:CAS:528:DC%2BD2cXlsVCgtw%3D%3D
-
Head MW, Ritchie D, Smith N, McLoughlin V, Nailon W, Samad S, Masson S, Bishop M, McCardle L, Ironside JW (2004) Peripheral tissue involvement in sporadic, iatrogenic, and variant Creutzfeldt-Jakob disease: An immunohistochemical, quantitative, and biochemical study. Am J Pathol 164:143-153 1:CAS:528:DC%2BD2cXlsVCgtw%3D%3D
-
(2004)
Am. J. Pathol.
, vol.164
, pp. 143-153
-
-
Head, M.W.1
Ritchie, D.2
Smith, N.3
McLoughlin, V.4
Nailon, W.5
Samad, S.6
Masson, S.7
Bishop, M.8
McCardle, L.9
Ironside, J.W.10
-
70
-
-
0032488777
-
A transmembrane form of the prion protein in neurodegenerative disease
-
10.1126/science.279.5352.827
-
Hegde RS, Mastrianni JA, Scott MR, DeFea KA, Tremblay P, Torchia M, DeArmond SJ, Prusiner SB, Lingappa VR (1998) A transmembrane form of the prion protein in neurodegenerative disease. Science 279:827-834 10.1126/ science.279.5352.827
-
(1998)
Science
, vol.279
, pp. 827-834
-
-
Hegde, R.S.1
Mastrianni, J.A.2
Scott, M.R.3
DeFea, K.A.4
Tremblay, P.5
Torchia, M.6
DeArmond, S.J.7
Prusiner, S.B.8
Lingappa, V.R.9
-
71
-
-
0033576323
-
Transmissible and genetic prion diseases share a common pathway of neurodegeneration
-
10.1038/45574
-
Hegde RS, Tremblay P, Groth D, DeArmond SJ, Prusiner SB, Lingappa VR (1999) Transmissible and genetic prion diseases share a common pathway of neurodegeneration. Nature 402:822-826 10.1038/45574
-
(1999)
Nature
, vol.402
, pp. 822-826
-
-
Hegde, R.S.1
Tremblay, P.2
Groth, D.3
DeArmond, S.J.4
Prusiner, S.B.5
Lingappa, V.R.6
-
72
-
-
0034797467
-
Transepithelial prion transport by M cells
-
Heppner FL, Christ AD, Klein MA, Prinz M, Fried M, Kraehenbuhl JP, Aguzzi A (2001) Transepithelial prion transport by M cells. Nat Med 7:976-977
-
(2001)
Nat. Med.
, vol.7
, pp. 976-977
-
-
Heppner, F.L.1
Christ, A.D.2
Klein, M.A.3
Prinz, M.4
Fried, M.5
Kraehenbuhl, J.P.6
Aguzzi, A.7
-
73
-
-
0142105406
-
Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein
-
10.1093/emboj/cdg537
-
Hetz C, Russelakis-Carneiro M, Maundrell K, Castilla J, Soto C (2003) Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein. EMBO J 22:5435-5445 10.1093/emboj/cdg537
-
(2003)
EMBO J.
, vol.22
, pp. 5435-5445
-
-
Hetz, C.1
Russelakis-Carneiro, M.2
Maundrell, K.3
Castilla, J.4
Soto, C.5
-
74
-
-
0033573778
-
Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples
-
10.1016/S0140-6736(98)12075-5
-
Hill AF, Butterworth RJ, Joiner S, Jackson G, Rossor MN, Thomas DJ, Frosh A, Tolley N, Bell JE, Spencer M, King A, Al-Sarraj S, Ironside JW, Lantos PL, Collinge J (1999) Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples. Lancet 353:183-189 10.1016/S0140-6736(98)12075-5
-
(1999)
Lancet
, vol.353
, pp. 183-189
-
-
Hill, A.F.1
Butterworth, R.J.2
Joiner, S.3
Jackson, G.4
Rossor, M.N.5
Thomas, D.J.6
Frosh, A.7
Tolley, N.8
Bell, J.E.9
Spencer, M.10
King, A.11
Al-Sarraj, S.12
Ironside, J.W.13
Lantos, P.L.14
Collinge, J.15
-
75
-
-
0037677595
-
Molecular classification of sporadic Creutzfeldt-Jakob disease
-
10.1093/brain/awg125
-
Hill AF, Joiner S, Wadsworth JDF, Sidle KCL, Bell JE, Budka H, Ironside JW, Collinge J (2003) Molecular classification of sporadic Creutzfeldt-Jakob disease. Brain 126:1333-1346 10.1093/brain/awg125
-
(2003)
Brain
, vol.126
, pp. 1333-1346
-
-
Hill, A.F.1
Joiner, S.2
Wadsworth, J.D.F.3
Sidle, K.C.L.4
Bell, J.E.5
Budka, H.6
Ironside, J.W.7
Collinge, J.8
-
76
-
-
0028883341
-
Copper binding to the N-terminal tandem repeat regions of mammalian and avian prion protein
-
10.1006/bbrc.1995.1233
-
Hornshaw MP, McDermott JR, Candy JM (1995) Copper binding to the N-terminal tandem repeat regions of mammalian and avian prion protein. Biochem Biophys Res Commun 207:621-629 10.1006/bbrc.1995.1233
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.207
, pp. 621-629
-
-
Hornshaw, M.P.1
McDermott, J.R.2
Candy, J.M.3
-
77
-
-
0036135693
-
Migrating intestinal dendritic cells transport PrP(Sc) from the gut
-
1:CAS:528:DC%2BD38Xlt1Gkug%3D%3D
-
Huang FP, Farquhar CF, Mabbott NA, Bruce ME, MacPherson GG (2002) Migrating intestinal dendritic cells transport PrP(Sc) from the gut. J Gen Virol 83:267-271 1:CAS:528:DC%2BD38Xlt1Gkug%3D%3D
-
(2002)
J. Gen. Virol.
, vol.83
, pp. 267-271
-
-
Huang, F.P.1
Farquhar, C.F.2
Mabbott, N.A.3
Bruce, M.E.4
MacPherson, G.G.5
-
78
-
-
0021543112
-
The presence of complements in amyloid plaques of Creutzfeldt-Jakob disease and Gerstmann-Straussler-Scheinker disease
-
1:STN:280:BiiD3c%2FivVE%3D
-
Ishii T, Haga S, Yagishita S, Tateishi J (1984) The presence of complements in amyloid plaques of Creutzfeldt-Jakob disease and Gerstmann-Straussler-Scheinker disease. Appl Pathol 2:370-379 1:STN:280:BiiD3c%2FivVE%3D
-
(1984)
Appl. Pathol.
, vol.2
, pp. 370-379
-
-
Ishii, T.1
Haga, S.2
Yagishita, S.3
Tateishi, J.4
-
79
-
-
0033947543
-
Sites of prion protein accumulation in scrapie-infected mouse spleen revealed by immuno-electron microscopy
-
10.1002/1096-9896(200007)191:3<323::AID-PATH629>3.3.CO;2-Q
-
Jeffrey M, McGovern G, Goodsir CM, Brown KL, Bruce ME (2000) Sites of prion protein accumulation in scrapie-infected mouse spleen revealed by immuno-electron microscopy. J Pathol 191:323-332 10.1002/ 1096-9896(200007)191:3<323::AID-PATH629>3.3.CO;2-Q
-
(2000)
J. Pathol.
, vol.191
, pp. 323-332
-
-
Jeffrey, M.1
McGovern, G.2
Goodsir, C.M.3
Brown, K.L.4
Bruce, M.E.5
-
80
-
-
2542638001
-
Scrapie-specific neuronal lesions are independent of neuronal PrP expression
-
10.1002/ana.20093
-
Jeffrey M, Goodsir CM, Race RE, Chesebro B (2004) Scrapie-specific neuronal lesions are independent of neuronal PrP expression. Ann Neurol 55:781-792 10.1002/ana.20093
-
(2004)
Ann. Neurol.
, vol.55
, pp. 781-792
-
-
Jeffrey, M.1
Goodsir, C.M.2
Race, R.E.3
Chesebro, B.4
-
81
-
-
0026069894
-
Proteinase-resistant prion protein accumulation in Syrian hamster brain correlates with regional pathology and scrapie infectivity
-
1:CAS:528:DyaK3MXmslKrsbs%3D
-
Jendroska K, Heinzel FP, Torchia M, Stowring L, Kretzschmar HA, Kon A, Stern A, Prusiner SB, DeArmond SJ (1991) Proteinase-resistant prion protein accumulation in Syrian hamster brain correlates with regional pathology and scrapie infectivity. Neurology 41:1482-1490 1:CAS:528:DyaK3MXmslKrsbs%3D
-
(1991)
Neurology
, vol.41
, pp. 1482-1490
-
-
Jendroska, K.1
Heinzel, F.P.2
Torchia, M.3
Stowring, L.4
Kretzschmar, H.A.5
Kon, A.6
Stern, A.7
Prusiner, S.B.8
DeArmond, S.J.9
-
82
-
-
0038946003
-
Conversion by Peyer's patch lymphocytes of human enterocytes into M cells that transport bacteria
-
10.1126/science.277.5328.949
-
Kerneis S, Bogdanova A, Kraehenbuhl JP, Pringault E (1997) Conversion by Peyer's patch lymphocytes of human enterocytes into M cells that transport bacteria. Science 277:949-952 10.1126/science.277.5328.949
-
(1997)
Science
, vol.277
, pp. 949-952
-
-
Kerneis, S.1
Bogdanova, A.2
Kraehenbuhl, J.P.3
Pringault, E.4
-
83
-
-
0015383455
-
Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
-
1:STN:280:CSyD3crgslU%3D
-
Kerr JF, Wyllie AH, Currie AR (1972) Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26:239-257 1:STN:280:CSyD3crgslU%3D
-
(1972)
Br. J. Cancer
, vol.26
, pp. 239-257
-
-
Kerr, J.F.1
Wyllie, A.H.2
Currie, A.R.3
-
84
-
-
0021088568
-
Pathogenesis of mouse scrapie. Evidence for direct neural spread of infection to the CNS after injection of sciatic nerve
-
10.1016/0022-510X(83)90165-X
-
Kimberlin RH, Hall SM, Walker CA (1983) Pathogenesis of mouse scrapie. Evidence for direct neural spread of infection to the CNS after injection of sciatic nerve. J Neurol Sci 61:315-325 10.1016/ 0022-510X(83)90165-X
-
(1983)
J. Neurol. Sci.
, vol.61
, pp. 315-325
-
-
Kimberlin, R.H.1
Hall, S.M.2
Walker, C.A.3
-
85
-
-
0025983158
-
Abnormal isoform of prion protein accumulates in follicular dendritic cells in mice with Creutzfeldt-Jakob disease
-
1:CAS:528:DyaK3MXmsFeisLY%3D
-
Kitamoto T, Muramoto T, Mohri S, Doh-Ura K, Tateishi J (1991) Abnormal isoform of prion protein accumulates in follicular dendritic cells in mice with Creutzfeldt-Jakob disease. J Virol 65:6292-6295 1:CAS:528:DyaK3MXmsFeisLY%3D
-
(1991)
J. Virol.
, vol.65
, pp. 6292-6295
-
-
Kitamoto, T.1
Muramoto, T.2
Mohri, S.3
Doh-Ura, K.4
Tateishi, J.5
-
86
-
-
0031444295
-
A crucial role for B cells in neuroinvasive scrapie
-
1:CAS:528:DyaK1cXhtVWgtg%3D%3D
-
Klein MA, Frigg R, Flechsig E, Raeber AJ, Kalinke U, Bluethmann H, Bootz F, Suter M, Zinkernagel RM, Aguzzi A (1997) A crucial role for B cells in neuroinvasive scrapie. Nature 390:687-690 1:CAS:528:DyaK1cXhtVWgtg%3D%3D
-
(1997)
Nature
, vol.390
, pp. 687-690
-
-
Klein, M.A.1
Frigg, R.2
Flechsig, E.3
Raeber, A.J.4
Kalinke, U.5
Bluethmann, H.6
Bootz, F.7
Suter, M.8
Zinkernagel, R.M.9
Aguzzi, A.10
-
87
-
-
0031759918
-
PrP expression in B lymphocytes is not required for prion neuroinvasion
-
Klein MA, Frigg R, Raeber AJ, Flechsig E, Hegyi I, Zinkernagel RM, Weissmann C, Aguzzi A (1998) PrP expression in B lymphocytes is not required for prion neuroinvasion. Nat Med 4:1429-1433
-
(1998)
Nat. Med.
, vol.4
, pp. 1429-1433
-
-
Klein, M.A.1
Frigg, R.2
Raeber, A.J.3
Flechsig, E.4
Hegyi, I.5
Zinkernagel, R.M.6
Weissmann, C.7
Aguzzi A8
-
88
-
-
0035047889
-
Complement facilitates early prion pathogenesis
-
Klein MA, Kaeser PS, Schwarz P, Weyd H, Xenarios I, Zinkernagel RM, Carroll MC, Verbeek JS, Botto M, Walport MJ, Molina H, Kalinke U, Acha-Orbea H, Aguzzi A (2001) Complement facilitates early prion pathogenesis. Nat Med 7:488-492
-
(2001)
Nat. Med.
, vol.7
, pp. 488-492
-
-
Klein, M.A.1
Kaeser, P.S.2
Schwarz, P.3
Weyd, H.4
Xenarios, I.5
Zinkernagel, R.M.6
Carroll, M.C.7
Verbeek, J.S.8
Botto, M.9
Walport, M.J.10
Molina, H.11
Kalinke, U.12
Acha-Orbea, H.13
Aguzzi, A.14
-
89
-
-
0036901006
-
Disease-associated prion protein in vessel walls
-
1:CAS:528:DC%2BD38Xpslemtb0%3D
-
Koperek O, Kovacs GG, Ritchie D, Ironside JW, Budka H, Wick G (2002) Disease-associated prion protein in vessel walls. Am J Pathol 161:1979-1984 1:CAS:528:DC%2BD38Xpslemtb0%3D
-
(2002)
Am. J. Pathol.
, vol.161
, pp. 979-1984
-
-
Koperek, O.1
Kovacs, G.G.2
Ritchie, D.3
Ironside, J.W.4
Budka, H.5
Wick, G.6
-
90
-
-
0032731551
-
Deposition of the prion protein (PrP) during the evolution of experimental Creutzfeldt-Jakob disease
-
10.1007/s004010051124
-
Kordek R, Hainfellner JA, Liberski PP, Budka H (1999) Deposition of the prion protein (PrP) during the evolution of experimental Creutzfeldt-Jakob disease. Acta Neuropathol 98:597-602 10.1007/ s004010051124
-
(1999)
Acta Neuropathol.
, vol.98
, pp. 597-602
-
-
Kordek, R.1
Hainfellner, J.A.2
Liberski, P.P.3
Budka, H.4
-
91
-
-
0036934561
-
Distribution of intraneuronal immunoreactivity for the prion protein in human prion diseases
-
1:CAS:528:DC%2BD38Xls12ntr8%3D
-
Kovacs GG, Voigtländer T, Hainfellner JA, Budka H (2002) Distribution of intraneuronal immunoreactivity for the prion protein in human prion diseases. Acta Neuropathol 104:320-326 1:CAS:528:DC%2BD38Xls12ntr8%3D
-
(2002)
Acta Neuropathol.
, vol.104
, pp. 320-326
-
-
Kovacs, G.G.1
Voigtländer, T.2
Hainfellner, J.A.3
Budka, H.4
-
92
-
-
0037031611
-
The prion protein in human neurodegenerative disorders
-
Kovacs GG, Zerbi P, Voigtländer T, Strohschneider M, Trabattoni G, Hainfellner JA, Budka H (2002) The prion protein in human neurodegenerative disorders. Neurosci Lett 329:269-272
-
(2002)
Neurosci. Lett.
, vol.329
, pp. 269-272
-
-
Kovacs, G.G.1
Zerbi, P.2
Voigtländer, T.3
Strohschneider, M.4
Trabattoni, G.5
Hainfellner, J.A.6
Budka, H.7
-
93
-
-
1642456624
-
Complement activation in human prion disease
-
10.1016/j.nbd.2003.09.010
-
Kovacs GG, Gasque P, Ströbel T, Lindeck-Pozza E, Strohschneider M, Ironside JW, Budka H, Guentchev M (2004) Complement activation in human prion disease. Neurobiol Dis 15:21-28 10.1016/j.nbd.2003.09.010
-
(2004)
Neurobiol. Dis.
, vol.15
, pp. 21-28
-
-
Kovacs, G.G.1
Gasque, P.2
Ströbel, T.3
Lindeck-Pozza, E.4
Strohschneider, M.5
Ironside, J.W.6
Budka, H.7
Guentchev, M.8
-
96
-
-
0036759121
-
Unhampered prion neuroinvasion despite impaired fast axonal transport in transgenic mice overexpressing four-repeat tau
-
Kunzi V, Glatzel M, Nakano MY, Greber UF, Van Leuven F, Aguzzi A (2002) Unhampered prion neuroinvasion despite impaired fast axonal transport in transgenic mice overexpressing four-repeat tau. J Neurosci 22:7471-7477
-
(2002)
J. Neurosci.
, vol.22
, pp. 7471-7477
-
-
Kunzi, V.1
Glatzel, M.2
Nakano, M.Y.3
Greber, U.F.4
Van Leuven, F.5
Aguzzi, A.6
-
97
-
-
0032772928
-
Alteration of free radical metabolism in the brain of mice infected with scrapie agent
-
1:CAS:528:DyaK1MXktFWltLo%3D
-
Lee DW, Sohn HO, Lim HB, Lee YG, Kim YS, Carp RI, Wisniewski HM (1999) Alteration of free radical metabolism in the brain of mice infected with scrapie agent. Free Radic Res 30:499-507 1:CAS:528:DyaK1MXktFWltLo%3D
-
(1999)
Free Radic. Res.
, vol.30
, pp. 499-507
-
-
Lee, D.W.1
Sohn, H.O.2
Lim, H.B.3
Lee, Y.G.4
Kim, Y.S.5
Carp, R.I.6
Wisniewski, H.M.7
-
98
-
-
3442889359
-
Synthetic mammalian prions
-
10.1126/science.1100195
-
Legname G, Baskakov IV, Nguyen HOB, Riesner D, Cohen FE, DeArmond SJ, Prusiner SB (2004) Synthetic mammalian prions. Science 305:673-676 10.1126/science.1100195
-
(2004)
Science
, vol.305
, pp. 673-676
-
-
Legname, G.1
Baskakov, I.V.2
Nguyen, H.O.B.3
Riesner, D.4
Cohen, F.E.5
DeArmond, S.J.6
Prusiner, S.B.7
-
99
-
-
4344656906
-
Neuronal cell death in transmissible spongiform encephalopathies (prion diseases) revisited: From apoptosis to autophagy
-
10.1016/j.biocel.2004.04.016
-
Liberski PP, Sikorska B, Bratosiewicz-Wasik J, Gajdusek DC, Brown P (2004) Neuronal cell death in transmissible spongiform encephalopathies (prion diseases) revisited: From apoptosis to autophagy. Int J Biochem Cell Biol 36:2473-2490 10.1016/j.biocel.2004.04.016
-
(2004)
Int. J. Biochem. Cell Biol.
, vol.36
, pp. 2473-2490
-
-
Liberski, P.P.1
Sikorska, B.2
Bratosiewicz-Wasik, J.3
Gajdusek, D.C.4
Brown, P.5
-
100
-
-
0034099095
-
Tumor necrosis factor alpha-deficient, but not interleukin-6-deficient, mice resist peripheral infection with scrapie
-
10.1128/JVI.74.7.3338-3344.2000
-
Mabbott NA, Williams A, Farquhar CF, Pasparakis M, Kollias G, Bruce ME (2000) Tumor necrosis factor alpha-deficient, but not interleukin-6-deficient, mice resist peripheral infection with scrapie. J Virol 74:3338-3344 10.1128/JVI.74.7.3338-3344.2000
-
(2000)
J. Virol.
, vol.74
, pp. 3338-3344
-
-
Mabbott, N.A.1
Williams, A.2
Farquhar, C.F.3
Pasparakis, M.4
Kollias, G.5
Bruce, M.E.6
-
101
-
-
0035053039
-
Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie
-
Mabbott NA, Bruce ME, Botto M, Walport MJ, Pepys MB (2001) Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie. Nat Med 7:485-487
-
(2001)
Nat. Med.
, vol.7
, pp. 485-487
-
-
Mabbott, N.A.1
Bruce, M.E.2
Botto, M.3
Walport, M.J.4
Pepys, M.B.5
-
102
-
-
0036470471
-
Post-natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegeneration
-
10.1093/emboj/21.3.202
-
Mallucci GR, Ratté S, Asante EA, Linehan J, Gowland I, Jefferys JGR, Collinge J (2002) Post-natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegeneration. EMBO J 21:202-210 10.1093/emboj/21.3.202
-
(2002)
EMBO J.
, vol.21
, pp. 202-210
-
-
Mallucci, G.R.1
Ratté, S.2
Asante, E.A.3
Linehan, J.4
Gowland, I.5
Jefferys, J.G.R.6
Collinge, J.7
-
103
-
-
0242363656
-
Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis
-
10.1126/science.1090187
-
Mallucci G, Dickinson A, Linehan J, Klöhn PC, Brandner S, Collinge J (2003) Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis. Science 302:871-874 10.1126/science.1090187
-
(2003)
Science
, vol.302
, pp. 871-874
-
-
Mallucci, G.1
Dickinson, A.2
Linehan, J.3
Klöhn, P.C.4
Brandner, S.5
Collinge, J.6
-
104
-
-
0028420937
-
129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal
-
1:CAS:528:DyaK2cXmt1Olu74%3D
-
Manson JC, Clarke AR, Hooper ML, Aitchison L, McConnell I, Hope J (1994) 129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal. Mol Neurobiol 8:121-127 1:CAS:528:DyaK2cXmt1Olu74%3D
-
(1994)
Mol. Neurobiol.
, vol.8
, pp. 121-127
-
-
Manson, J.C.1
Clarke, A.R.2
Hooper, M.L.3
Aitchison, L.4
McConnell, I.5
Hope, J.6
-
105
-
-
0028703452
-
PrP gene dosage determines the timing but not the final intensity or distribution of lesions in scrapie pathology
-
1:STN:280:ByqC2cvlsFM%3D
-
Manson JC, Clarke AR, McBride PA, McConnell I, Hope J (1994) PrP gene dosage determines the timing but not the final intensity or distribution of lesions in scrapie pathology. Neurodegeneration 3:331-340 1:STN:280:ByqC2cvlsFM%3D
-
(1994)
Neurodegeneration
, vol.3
, pp. 331-340
-
-
Manson, J.C.1
Clarke, A.R.2
McBride, P.A.3
McConnell, I.4
Hope, J.5
-
106
-
-
2642623590
-
Distinct roles of lymphotoxin alpha and the type I tumor necrosis factor (TNF) receptor in the establishment of follicular dendritic cells from non-bone marrow-derived cells
-
10.1084/jem.186.12.1997
-
Matsumoto M, Fu YX, Molina H, Huang G, Kim J, Thomas DA, Nahm MH, Chaplin DD (1997) Distinct roles of lymphotoxin alpha and the type I tumor necrosis factor (TNF) receptor in the establishment of follicular dendritic cells from non-bone marrow-derived cells. J Exp Med 186:1997-2004 10.1084/jem.186.12.1997
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1997-2004
-
-
Matsumoto, M.1
Fu, Y.X.2
Molina, H.3
Huang, G.4
Kim, J.5
Thomas, D.A.6
Nahm, M.H.7
Chaplin, D.D.8
-
107
-
-
0033574604
-
Pathological PrP is abundant in sympathetic and sensory ganglia of hamsters fed with scrapie
-
McBride PA, Beekes M (1999) Pathological PrP is abundant in sympathetic and sensory ganglia of hamsters fed with scrapie. Neurosci Lett 265:135-138
-
(1999)
Neurosci. Lett.
, vol.265
, pp. 135-138
-
-
McBride, P.A.1
Beekes, M.2
-
108
-
-
0035910498
-
Cleavage of the amino terminus of the prion protein by reactive oxygen species
-
10.1074/jbc.M007243200
-
McMahon HEM, Mangé A, Nishida N, Créminon C, Casanova D, Lehmann S (2001) Cleavage of the amino terminus of the prion protein by reactive oxygen species. J Biol Chem 276:2286-2291 10.1074/jbc.M007243200
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 2286-2291
-
-
McMahon, H.E.M.1
Mangé, A.2
Nishida, N.3
Créminon, C.4
Casanova, D.5
Lehmann, S.6
-
109
-
-
0023095066
-
Lack of effect of thymus and spleen on the incubation period of Creutzfeldt-Jakob disease in mice
-
3553423
-
Mohri S, Handa S, Tateishi J (1987) Lack of effect of thymus and spleen on the incubation period of Creutzfeldt-Jakob disease in mice. J Gen Virol 68:1187-1189 3553423
-
(1987)
J. Gen. Virol.
, vol.68
, pp. 1187-1189
-
-
Mohri, S.1
Handa, S.2
Tateishi, J.3
-
110
-
-
0034686002
-
Impaired prion replication in spleens of mice lacking functional follicular dendritic cells
-
10.1126/science.288.5469.1257
-
Montrasio F, Frigg R, Glatzel M, Klein MA, Mackay F, Aguzzi A, Weissmann C (2000) Impaired prion replication in spleens of mice lacking functional follicular dendritic cells. Science 288:1257-1259 10.1126/ science.288.5469.1257
-
(2000)
Science
, vol.288
, pp. 1257-1259
-
-
Montrasio, F.1
Frigg, R.2
Glatzel, M.3
Klein, M.A.4
Mackay, F.5
Aguzzi, A.6
Weissmann, C.7
-
111
-
-
0033215478
-
Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel
-
1:CAS:528:DyaK1MXms1Cqs78%3D
-
Moore RC, Lee IY, Silverman GL, Harrison PM, Strome R, Heinrich C, Karunaratne A, Pasternak SH, Chishti MA, Liang Y, Mastrangelo P, Wang K, Smit AF, Katamine S, Carlson GA, Cohen FE, Prusiner SB, Melton DW, Tremblay P, Hood LE, Westaway D (1999) Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel. J Mol Biol 292:797-817 1:CAS:528:DyaK1MXms1Cqs78%3D
-
(1999)
J. Mol. Biol.
, vol.292
, pp. 797-817
-
-
Moore, R.C.1
Lee, I.Y.2
Silverman, G.L.3
Harrison, P.M.4
Strome, R.5
Heinrich, C.6
Karunaratne, A.7
Pasternak, S.H.8
Chishti, M.A.9
Liang, Y.10
Mastrangelo, P.11
Wang, K.12
Smit, A.F.13
Katamine, S.14
Carlson, G.A.15
Cohen, F.E.16
Prusiner, S.B.17
Melton, D.W.18
Tremblay, P.19
Hood, L.E.20
Westaway, D.21
more..
-
112
-
-
0035941307
-
Prion protein fragment PrP-(106-126) induces apoptosis via mitochondrial disruption in human neuronal SH-SY5Y cells
-
10.1074/jbc.M103894200
-
O'Donovan CN, Tobin D, Cotter TG (2001) Prion protein fragment PrP-(106-126) induces apoptosis via mitochondrial disruption in human neuronal SH-SY5Y cells. J Biol Chem 276:43516-43523 10.1074/ jbc.M103894200
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 43516-43523
-
-
O'Donovan, C.N.1
Tobin, D.2
Cotter, T.G.3
-
113
-
-
0026732669
-
Site-specific and random fragmentation of Cu,Zn-superoxide dismutase by glycation reaction. Implication of reactive oxygen species
-
1:CAS:528:DyaK38XltVOjt7s%3D
-
Ookawara T, Kawamura N, Kitagawa Y, Taniguchi N (1992) Site-specific and random fragmentation of Cu,Zn-superoxide dismutase by glycation reaction. Implication of reactive oxygen species. J Biol Chem 267:18505-18510 1:CAS:528:DyaK38XltVOjt7s%3D
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 18505-18510
-
-
Ookawara, T.1
Kawamura, N.2
Kitagawa, Y.3
Taniguchi, N.4
-
114
-
-
0032816292
-
Classification of sporadic Creutzfeldt-Jakob disease based on molecular and phenotypic analysis of 300 subjects
-
10.1002/1531-8249(199908)46:2<224::AID-ANA12>3.3.CO;2-N
-
Parchi P, Giese A, Capellari S, Brown P, Schulz-Schaeffer W, Windl O, Zerr I, Budka H, Kopp N, Piccardo P, Poser S, Rojiani A, Streichemberger N, Julien J, Vital C, Ghetti B, Gambetti P, Kretzschmar H (1999) Classification of sporadic Creutzfeldt-Jakob disease based on molecular and phenotypic analysis of 300 subjects. Ann Neurol 46:224-233 10.1002/ 1531-8249(199908)46:2<224::AID-ANA12>3.3.CO;2-N
-
(1999)
Ann. Neurol.
, vol.46
, pp. 224-233
-
-
Parchi, P.1
Giese, A.2
Capellari, S.3
Brown, P.4
Schulz-Schaeffer, W.5
Windl, O.6
Zerr, I.7
Budka, H.8
Kopp, N.9
Piccardo, P.10
Poser, S.11
Rojiani, A.12
Streichemberger, N.13
Julien, J.14
Vital, C.15
Ghetti, B.16
Gambetti, P.17
Kretzschmar, H.18
-
115
-
-
0032509499
-
Copper stimulates endocytosis of the prion protein
-
10.1074/jbc.273.50.33107
-
Pauly PC, Harris DA (1998) Copper stimulates endocytosis of the prion protein. J Biol Chem 273:33107-33110 10.1074/jbc.273.50.33107
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 33107-33110
-
-
Pauly, P.C.1
Harris, D.A.2
-
116
-
-
0036267207
-
A typical inflammation in the central nervous system in prion disease
-
10.1097/00019052-200206000-00020
-
Perry VH, Cunningham C, Boche D (2002) Atypical inflammation in the central nervous system in prion disease. Curr Opin Neurol 15:349-354 10.1097/00019052-200206000-00020
-
(2002)
Curr. Opin. Neurol.
, vol.15
, pp. 349-354
-
-
Perry, V.H.1
Cunningham, C.2
Boche, D.3
-
117
-
-
0033577152
-
Microglial cells respond to amyloidogenic PrP peptide by the production of inflammatory cytokines
-
1:CAS:528:DyaK1MXivVClur8%3D
-
Peyrin JM, Lasmézas CI, Haïk S, Tagliavini F, Salmona M, Williams A, Richie D, Deslys JP, Dormont D (1999) Microglial cells respond to amyloidogenic PrP peptide by the production of inflammatory cytokines. Neuroreport 10:723-729 1:CAS:528:DyaK1MXivVClur8%3D
-
(1999)
Neuroreport
, vol.10
, pp. 723-729
-
-
Peyrin, J.M.1
Lasmézas, C.I.2
Haïk, S.3
Tagliavini, F.4
Salmona, M.5
Williams, A.6
Richie, D.7
Deslys, J.P.8
Dormont, D.9
-
118
-
-
0037154263
-
Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells
-
Prinz M, Montrasio F, Klein MA, Schwarz P, Priller J, Odermatt B, Pfeffer K, Aguzzi A (2002) Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells. Proc Natl Acad Sci USA 99:919-924
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 919-924
-
-
Prinz, M.1
Montrasio, F.2
Klein, M.A.3
Schwarz, P.4
Priller, J.5
Odermatt, B.6
Pfeffer, K.7
Aguzzi, A.8
-
119
-
-
0037377727
-
Oral prion infection requires normal numbers of Peyer's patches but not of enteric lymphocytes
-
1:CAS:528:DC%2BD3sXjtVemt7c%3D
-
Prinz M, Huber G, Macpherson AJ, Heppner FL, Glatzel M, Eugster HP, Wagner N, Aguzzi A (2003) Oral prion infection requires normal numbers of Peyer's patches but not of enteric lymphocytes. Am J Pathol 162:1103-1111 1:CAS:528:DC%2BD3sXjtVemt7c%3D
-
(2003)
Am. J. Pathol.
, vol.162
, pp. 1103-1111
-
-
Prinz, M.1
Huber, G.2
Macpherson, A.J.3
Heppner, F.L.4
Glatzel, M.5
Eugster, H.P.6
Wagner, N.7
Aguzzi, A.8
-
120
-
-
3042712413
-
Intrinsic resistance of oligodendrocytes to prion infection
-
Prinz M, Montrasio F, Furukawa H, Haar ME van der, Schwarz P, Rülicke T, Giger OT, Häusler KG, Perez D, Glatzel M, Aguzzi A (2004) Intrinsic resistance of oligodendrocytes to prion infection. J Neurosci 24:5974-5981
-
(2004)
J. Neurosci.
, vol.24
, pp. 5974-5981
-
-
Prinz, M.1
Montrasio, F.2
Furukawa, H.3
van der Haar, M.E.4
Schwarz, P.5
Rülicke, T.6
Giger, O.T.7
Häusler, K.G.8
Perez, D.9
Glatzel, M.10
Aguzzi, A.11
-
121
-
-
0032506187
-
Prions
-
10.1073/pnas.95.23.13363
-
Prusiner SB (1998) Prions. Proc Natl Acad Sci USA 95:13363-13383 10.1073/pnas.95.23.13363
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 13363-13383
-
-
Prusiner, S.B.1
-
122
-
-
0034705438
-
Copper(II)-induced conformational changes and protease resistance in recombinant and cellular PrP. Effect of protein age and deamidation
-
10.1074/jbc.275.25.19121
-
Qin K, Yang DS, Yang Y, Chishti MA, Meng LJ, Kretzschmar HA, Yip CM, Fraser PE, Westaway D (2000) Copper(II)-induced conformational changes and protease resistance in recombinant and cellular PrP. Effect of protein age and deamidation. J Biol Chem 275:19121-19131 10.1074/ jbc.275.25.19121
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 19121-19131
-
-
Qin, K.1
Yang, D.S.2
Yang, Y.3
Chishti, M.A.4
Meng, L.J.5
Kretzschmar, H.A.6
Yip, C.M.7
Fraser, P.E.8
Westaway, D.9
-
123
-
-
0035815738
-
Copper converts the cellular prion protein into a protease-resistant species that is distinct from the scrapie isoform
-
10.1074/jbc.M009666200
-
Quaglio E, Chiesa R, Harris DA (2001) Copper converts the cellular prion protein into a protease-resistant species that is distinct from the scrapie isoform. J Biol Chem 276:11432-11438 10.1074/jbc.M009666200
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 11432-11438
-
-
Quaglio, E.1
Chiesa, R.2
Harris, D.A.3
-
124
-
-
0028876414
-
Neuron-specific expression of a hamster prion protein minigene in transgenic mice induces susceptibility to hamster scrapie agent
-
10.1016/0896-6273(95)90105-1
-
Race RE, Priola SA, Bessen RA, Ernst D, Dockter J, Rall GF, Mucke L, Chesebro B, Oldstone MB (1995) Neuron-specific expression of a hamster prion protein minigene in transgenic mice induces susceptibility to hamster scrapie agent. Neuron 15:1183-1191 10.1016/0896-6273(95)90105-1
-
(1995)
Neuron
, vol.15
, pp. 1183-1191
-
-
Race, R.E.1
Priola, S.A.2
Bessen, R.A.3
Ernst, D.4
Dockter, J.5
Rall, G.F.6
Mucke, L.7
Chesebro, B.8
Oldstone, M.B.9
-
125
-
-
0037715143
-
Expression of prion protein increases cellular copper binding and antioxidant enzyme activities but not copper delivery
-
10.1074/jbc.M211830200
-
Rachidi W, Vilette D, Guiraud P, Arlotto M, Riondel J, Laude H, Lehmann S, Favier A (2003) Expression of prion protein increases cellular copper binding and antioxidant enzyme activities but not copper delivery. J Biol Chem 278:9064-9072 10.1074/jbc.M211830200
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 9064-9072
-
-
Rachidi, W.1
Vilette, D.2
Guiraud, P.3
Arlotto, M.4
Riondel, J.5
Laude, H.6
Lehmann, S.7
Favier, A.8
-
126
-
-
0030684056
-
Astrocyte-specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie
-
10.1093/emboj/16.20.6057
-
Raeber AJ, Race RE, Brandner S, Priola SA, Sailer A, Bessen RA, Mucke L, Manson J, Aguzzi A, Oldstone MBA, Weissmann C, Chesebro B (1997) Astrocyte-specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie. EMBO J 16:6057-6065 10.1093/emboj/16.20.6057
-
(1997)
EMBO J.
, vol.16
, pp. 6057-6065
-
-
Raeber, A.J.1
Race, R.E.2
Brandner, S.3
Priola, S.A.4
Sailer, A.5
Bessen, R.A.6
Mucke, L.7
Manson, J.8
Aguzzi, A.9
Oldstone, M.B.A.10
Weissmann, C.11
Chesebro, B.12
-
127
-
-
0031443822
-
Apoptosis and necrosis in toxicology: A continuum or distinct modes of cell death?
-
10.1016/S0163-7258(97)00037-5
-
Raffray M, Cohen GM (1997) Apoptosis and necrosis in toxicology: A continuum or distinct modes of cell death? Pharmacol Ther 75:153-177 10.1016/S0163-7258(97)00037-5
-
(1997)
Pharmacol. Ther.
, vol.75
, pp. 153-177
-
-
Raffray, M.1
Cohen, G.M.2
-
128
-
-
0035865398
-
Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain
-
1:CAS:528:DC%2BD3MXhsVyhtrk%3D
-
Rossi D, Cozzio A, Flechsig E, Klein MA, Rülicke T, Aguzzi A, Weissmann C (2001) Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain. EMBO J 20:694-702 1:CAS:528:DC%2BD3MXhsVyhtrk%3D
-
(2001)
EMBO J.
, vol.20
, pp. 694-702
-
-
Rossi, D.1
Cozzio, A.2
Flechsig, E.3
Klein, M.A.4
Rülicke, T.5
Aguzzi, A.6
Weissmann, C.7
-
129
-
-
13344282734
-
Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene
-
1:CAS:528:DyaK28Xit1Ols7c%3D
-
Sakaguchi S, Katamine S, Nishida N, Moriuchi R, Shigematsu K, Sugimoto T, Nakatani A, Kataoka Y, Houtani T, Shirabe S, Okada H, Hasegawa S, Miyamoto T, Noda T (1996) Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene. Nature 380:528-531 1:CAS:528:DyaK28Xit1Ols7c%3D
-
(1996)
Nature
, vol.380
, pp. 528-531
-
-
Sakaguchi, S.1
Katamine, S.2
Nishida, N.3
Moriuchi, R.4
Shigematsu, K.5
Sugimoto, T.6
Nakatani, A.7
Kataoka, Y.8
Houtani, T.9
Shirabe, S.10
Okada, H.11
Hasegawa, S.12
Miyamoto, T.13
Noda, T.14
-
130
-
-
0027257501
-
Immunohistochemical study of microglia in the Creutzfeldt-Jakob diseased brain
-
10.1007/BF00369445
-
Sasaki A, Hirato J, Nakazato Y (1993) Immunohistochemical study of microglia in the Creutzfeldt-Jakob diseased brain. Acta Neuropathol 86:337-344 10.1007/BF00369445
-
(1993)
Acta Neuropathol.
, vol.86
, pp. 337-344
-
-
Sasaki, A.1
Hirato, J.2
Nakazato, Y.3
-
131
-
-
0033985183
-
Apoptosis and the nervous system
-
Sastry PS, Rao KS (2000) Apoptosis and the nervous system. J Neurochem 74:1-20
-
(2000)
J. Neurochem.
, vol.74
, pp. 1-20
-
-
Sastry, P.S.1
Rao, K.S.2
-
132
-
-
0037611374
-
A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis
-
9343242
-
Schätzl HM, Laszlo L, Holtzman DM, Tatzelt J, DeArmond SJ, Weiner RI, Mobley WC, Prusiner SB (1997) A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis. J Virol 71:8821-8831 9343242
-
(1997)
J. Virol.
, vol.71
, pp. 8821-8831
-
-
Schätzl, H.M.1
Laszlo, L.2
Holtzman, D.M.3
Tatzelt, J.4
DeArmond, S.J.5
Weiner, R.I.6
Mobley, W.C.7
Prusiner, S.B.8
-
133
-
-
4344656905
-
Autophagy is a part of ultrastructural synaptic pathology in Creutzfeldt-Jakob disease: A brain biopsy study
-
10.1016/j.biocel.2004.04.014
-
Sikorska B, Liberski PP, Giraud P, Kopp N, Brown P (2004) Autophagy is a part of ultrastructural synaptic pathology in Creutzfeldt-Jakob disease: a brain biopsy study. Int J Biochem Cell Biol 36:2563-2573 10.1016/ j.biocel.2004.04.014
-
(2004)
Int. J. Biochem. Cell Biol.
, vol.36
, pp. 2563-2573
-
-
Sikorska, B.1
Liberski, P.P.2
Giraud, P.3
Kopp, N.4
Brown, P.5
-
134
-
-
0029888496
-
Oxidative stress in neurodegenerative diseases
-
10.1146/annurev.pa.36.040196.000503
-
Simonian NA, Coyle JT (1996) Oxidative stress in neurodegenerative diseases. Annu Rev Pharmacol Toxicol 36:83-106 10.1146/ annurev.pa.36.040196.000503
-
(1996)
Annu. Rev. Pharmacol. Toxicol.
, vol.36
, pp. 83-106
-
-
Simonian, N.A.1
Coyle, J.T.2
-
135
-
-
0035910518
-
Most pathogenic mutations do not alter the membrane topology of the prion protein
-
10.1074/jbc.M006763200
-
Stewart RS, Harris DA (2001) Most pathogenic mutations do not alter the membrane topology of the prion protein. J Biol Chem 276:2212-2220 10.1074/jbc.M006763200
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 2212-2220
-
-
Stewart, R.S.1
Harris, D.A.2
-
136
-
-
0242412541
-
Mutational analysis of topological determinants in prion protein (PrP) and measurement of transmembrane and cytosolic PrP during prion infection
-
10.1074/jbc.M307833200
-
Stewart RS, Harris DA (2003) Mutational analysis of topological determinants in prion protein (PrP) and measurement of transmembrane and cytosolic PrP during prion infection. J Biol Chem 278:45960-45968 10.1074/jbc.M307833200
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 45960-45968
-
-
Stewart, R.S.1
Harris, D.A.2
-
137
-
-
0035158658
-
A transmembrane form of the prion protein contains an uncleaved signal peptide and is retained in the endoplasmic reticulum
-
1:CAS:528:DC%2BD3MXjtVaqsLo%3D
-
Stewart RS, Drisaldi B, Harris DA (2001) A transmembrane form of the prion protein contains an uncleaved signal peptide and is retained in the endoplasmic reticulum. Mol Biol Cell 12:881-889 1:CAS:528:DC%2BD3MXjtVaqsLo%3D
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 88-89
-
-
Stewart, R.S.1
Drisaldi, B.2
Harris, D.A.3
-
138
-
-
0037083888
-
Metal imbalance and compromised antioxidant function are early changes in prion disease
-
10.1042/0264-6021:3620253
-
Thackray AM, Knight R, Haswell SJ, Bujdoso R, Brown DR (2002) Metal imbalance and compromised antioxidant function are early changes in prion disease. Biochem J 362:253-258 10.1042/0264-6021:3620253
-
(2002)
Biochem. J.
, vol.362
, pp. 253-258
-
-
Thackray, A.M.1
Knight, R.2
Haswell, S.J.3
Bujdoso, R.4
Brown, D.R.5
-
139
-
-
15844421385
-
Altered circadian activity rhythms and sleep in mice devoid of prion protein
-
10.1038/380639a0
-
Tobler I, Gaus SE, Deboer T, Achermann P, Fischer M, Rülicke T, Moser M, Oesch B, McBride PA, Manson JC (1996) Altered circadian activity rhythms and sleep in mice devoid of prion protein. Nature 380:639-642 10.1038/380639a0
-
(1996)
Nature
, vol.380
, pp. 639-642
-
-
Tobler, I.1
Gaus, S.E.2
Deboer, T.3
Achermann, P.4
Fischer, M.5
Rülicke, T.6
Moser, M.7
Oesch, B.8
McBride, P.A.9
Manson, J.C.10
-
140
-
-
0037461576
-
Copper-dependent generation of hydrogen peroxide from the toxic prion protein fragment PrP106-126
-
Turnbull S, Tabner BJ, Brown DR, Allsop D (2003) Copper-dependent generation of hydrogen peroxide from the toxic prion protein fragment PrP106-126. Neurosci Lett 336:159-162
-
(2003)
Neurosci. Lett.
, vol.336
, pp. 159-162
-
-
Turnbull, S.1
Tabner, B.J.2
Brown, D.R.3
Allsop, D.4
-
141
-
-
0029991473
-
Immunohistochemical detection of prion protein in lymphoid tissues of sheep with natural scrapie
-
8727908
-
Van Keulen LJ, Schreuder BE, Meloen RH, Mooij-Harkes G, Vromans M, Langeveld JP (1996) Immunohistochemical detection of prion protein in lymphoid tissues of sheep with natural scrapie. J Clin Microbiol 34:1228-1231 8727908
-
(1996)
J. Clin. Microbiol.
, vol.34
, pp. 1228-1231
-
-
Van Keulen, L.J.1
Schreuder, B.E.2
Meloen, R.H.3
Mooij-Harkes, G.4
Vromans, M.5
Langeveld, J.P.6
-
143
-
-
0024834589
-
Non-enzymic activation of the fifth component of human complement, by oxygen radicals. Some properties of the activation product, C5b-like C5
-
Vogt W, Damerau B, Zabern I von, Nolte R, Brunahl D (1989) Non-enzymic activation of the fifth component of human complement, by oxygen radicals. Some properties of the activation product, C5b-like C5. Mol Immunol 26:1133-1142
-
(1989)
Mol. Immunol.
, vol.26
, pp. 1133-1142
-
-
Vogt, W.1
Damerau, B.2
von Zabern, I.3
Nolte, R.4
Brunahl, D.5
-
144
-
-
0034963098
-
Marked increase of neuronal prion protein immunoreactivity in Alzheimer's disease and human prion diseases
-
1:CAS:528:DC%2BD3MXktVGmsLw%3D
-
Voigtländer T, Klöppel S, Birner P, Jarius C, Flicker H, Verghese-Nikolakaki S, Sklaviadis T, Guentchev M, Budka H (2001) Marked increase of neuronal prion protein immunoreactivity in Alzheimer's disease and human prion diseases. Acta Neuropathol 101:417-423 1:CAS:528:DC%2BD3MXktVGmsLw%3D
-
(2001)
Acta Neuropathol.
, vol.101
-
-
Voigtländer, T.1
Klöppel, S.2
Birner, P.3
Jarius, C.4
Flicker, H.5
Verghese-Nikolakaki, S.6
Sklaviadis, T.7
Guentchev, M.8
Budka, H.9
-
145
-
-
0028769524
-
Infectivity in the ileum of cattle challenged orally with bovine spongiform encephalopathy
-
1:STN:280:ByqD28rks1I%3D
-
Wells GA, Dawson M, Hawkins SA, Green RB, Dexter I, Francis ME, Simmons MM, Austin AR, Horigan MW (1994) Infectivity in the ileum of cattle challenged orally with bovine spongiform encephalopathy. Vet Rec 135:40-41 1:STN:280:ByqD28rks1I%3D
-
(1994)
Vet. Rec.
, vol.135
, pp. 40-41
-
-
Wells, G.A.1
Dawson, M.2
Hawkins, S.A.3
Green, R.B.4
Dexter, I.5
Francis, M.E.6
Simmons, M.M.7
Austin, A.R.8
Horigan, M.W.9
-
146
-
-
0032724766
-
Prion protein-deficient neurons reveal lower glutathione reductase activity and increased susceptibility to hydrogen peroxide toxicity
-
1:CAS:528:DyaK1MXnvVKisb4%3D
-
White AR, Collins SJ, Maher F, Jobling MF, Stewart LR, Thyer JM, Beyreuther K, Masters CL, Cappai R (1999) Prion protein-deficient neurons reveal lower glutathione reductase activity and increased susceptibility to hydrogen peroxide toxicity. Am J Pathol 155:1723-1730 1:CAS:528:DyaK1MXnvVKisb4%3D
-
(1999)
Am. J. Pathol.
, vol.155
, pp. 1723-1730
-
-
White, A.R.1
Collins, S.J.2
Maher, F.3
Jobling, M.F.4
Stewart, L.R.5
Thyer, J.M.6
Beyreuther, K.7
Masters, C.L.8
Cappai, R.9
-
147
-
-
0035029801
-
Sublethal concentrations of prion peptide PrP106-126 or the amyloid beta peptide of Alzheimer's disease activates expression of proapoptotic markers in primary cortical neurons
-
10.1006/nbdi.2001.0386
-
White AR, Guirguis R, Brazier MW, Jobling MF, Hill AF, Beyreuther K, Barrow CJ, Masters CL, Collins SJ, Cappai R (2001) Sublethal concentrations of prion peptide PrP106-126 or the amyloid beta peptide of Alzheimer's disease activates expression of proapoptotic markers in primary cortical neurons. Neurobiol Dis 8:299-316 10.1006/nbdi.2001.0386
-
(2001)
Neurobiol. Dis.
, vol.8
, pp. 299-316
-
-
White, A.R.1
Guirguis, R.2
Brazier, M.W.3
Jobling, M.F.4
Hill, A.F.5
Beyreuther, K.6
Barrow, C.J.7
Masters, C.L.8
Collins, S.J.9
Cappai, R.10
-
149
-
-
0031127379
-
PrP deposition, microglial activation, and neuronal apoptosis in murine scrapie
-
10.1006/exnr.1997.6424
-
Williams A, Lucassen PJ, Ritchie D, Bruce M (1997) PrP deposition, microglial activation, and neuronal apoptosis in murine scrapie. Exp Neurol 144:433-438 10.1006/exnr.1997.6424
-
(1997)
Exp. Neurol.
, vol.144
, pp. 433-438
-
-
Williams, A.1
Lucassen, P.J.2
Ritchie, D.3
Bruce, M.4
-
150
-
-
0030937917
-
2 and lipocortin-1 in the CNS during the incubation period of murine scrapie correlates with progressive PrP accumulations
-
10.1016/S0006-8993(97)00067-X
-
2 and lipocortin-1 in the CNS during the incubation period of murine scrapie correlates with progressive PrP accumulations. Brain Res 754:171-180 10.1016/S0006-8993(97)00067-X
-
(1997)
Brain Res.
, vol.754
, pp. 171-180
-
-
Williams, A.1
Van Dam, A.M.2
Ritchie, D.3
Eikelenboom, P.4
Fraser, H.5
-
151
-
-
0034764599
-
Oxidative impairment in scrapie-infected mice is associated with brain metals perturbations and altered antioxidant activities
-
10.1046/j.1471-4159.2001.00625.x
-
Wong BS, Brown DR, Pan T, Whiteman M, Liu T, Bu X, Li R, Gambetti P, Olesik J, Rubenstein R, Sy MS (2001) Oxidative impairment in scrapie-infected mice is associated with brain metals perturbations and altered antioxidant activities. J Neurochem 79:689-698 10.1046/ j.1471-4159.2001.00625.x
-
(2001)
J. Neurochem.
, vol.79
, pp. 689-698
-
-
Wong, B.S.1
Brown, D.R.2
Pan, T.3
Whiteman, M.4
Liu, T.5
Bu, X.6
Li, R.7
Gambetti, P.8
Olesik, J.9
Rubenstein, R.10
Sy, M.S.11
-
152
-
-
0034810585
-
Aberrant metal binding by prion protein in human prion disease
-
10.1046/j.1471-4159.2001.00522.x
-
Wong BS, Chen SG, Colucci M, Xie Z, Pan T, Liu T, Li R, Gambetti P, Sy MS, Brown DR (2001) Aberrant metal binding by prion protein in human prion disease. J Neurochem 78:1400-1408 10.1046/j.1471-4159.2001.00522.x
-
(2001)
J. Neurochem.
, vol.78
, pp. 1400-1408
-
-
Wong, B.S.1
Chen, S.G.2
Colucci, M.3
Xie, Z.4
Pan, T.5
Liu, T.6
Li, R.7
Gambetti, P.8
Sy, M.S.9
Brown, D.R.10
-
153
-
-
0027419446
-
Delayed internucleosomal DNA fragmentation in programmed cell death
-
1:CAS:528:DyaK3sXitlWisbo%3D
-
Zakeri ZF, Quaglino D, Latham T, Lockshin RA (1993) Delayed internucleosomal DNA fragmentation in programmed cell death. FASEB J 7:470-478 1:CAS:528:DyaK3sXitlWisbo%3D
-
(1993)
FASEB J.
, vol.7
, pp. 470-478
-
-
Zakeri, Z.F.1
Quaglino, D.2
Latham, T.3
Lockshin, R.A.4
|