Astrocyte-specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie

EMBO Journal

Volumn 16, Issue 20, 1997, Pages 6057-6065

  Raeber, Alex J ^a   Race, Richard E ^b   Brandner, Sebastian ^c   Priola, Suzette A ^b   Sailer, Andreas ^f   Bessen, Richard A ^b   Mucke, Lennart ^d,g   Manson, Jean ^e   Aguzzi, Adriano ^c   Oldstone, Michael B A ^d   Weissmann, Charles ^a   Chesebro, Bruce ^b  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

^e INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

^f SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^g GLADSTONE INSTITUTE OF NEUROLOGICAL DISEASE   (United States)

Author keywords

Astrocytes; Hamster scrapie prions; PrP; Transgenic mice

Indexed keywords

PRION PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL TYPE; CONTROLLED STUDY; DISEASE SEVERITY; HAMSTER; MOUSE; NONHUMAN; PATHOGENESIS; PRION DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCRAPIE; TRANSGENE;

ANIMALS; ASTROCYTES; BIOLOGICAL ASSAY; BRAIN; CRICETINAE; DISEASE SUSCEPTIBILITY; GLIAL FIBRILLARY ACIDIC PROTEIN; MICE; MICE, KNOCKOUT; PRIONS; PRPSC PROTEINS; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; RODENT DISEASES; SCRAPIE;

ANIMALIA; CRICETINAE; MURINAE; MUS MUSCULUS;

EID: 0030684056     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.20.6057     Document Type: Article

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