Copper(II)-induced conformational changes and protease resistance in recombinant and cellular PrP: Effect of protein age and deamidation

Journal of Biological Chemistry

Volumn 275, Issue 25, 2000, Pages 19121-19131

  Qin, Kefeng ^a   Yang, Dun Sheng ^a   Yang, Ying ^b   Chishti, M Azhar ^a   Meng, Ling Jie ^b   Kretzschmar, Hans A ^c   Yip, Christopher M ^b,d,e   Fraser, Paul E ^a,e   Westaway, David ^a,e  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF GÖTTINGEN   (Germany)

^d UNIVERSITY OF TORONTO   (Canada)

^e UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ENZYME; COPPER; PROTEINASE;

ALPHA HELIX; AMIDATION; ARTICLE; BRAIN MICROSOME; CONFORMATIONAL TRANSITION; CREUTZFELDT JAKOB DISEASE; DEAMINATION; ENZYME BINDING; ENZYME CONFORMATION; ENZYME INDUCTION; METAL BINDING; PRIORITY JOURNAL;

AMIDES; AMINO ACID SEQUENCE; ANIMALS; BRAIN; COPPER; DISULFIDES; ENDOPEPTIDASE K; MICE; MICROSOMES; PRIONS; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 0034705438     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.25.19121     Document Type: Article

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