The sequential role of lymphotoxin and B cells in the development of splenic follicles

Journal of Experimental Medicine

Volumn 187, Issue 7, 1998, Pages 997-1007

  Gonzalez, Mercedes ^a   Mackay, Fabienne ^b   Browning, Jeffrey L ^b   Kosco Vilbois, Marie H ^c   Noelle, Randolph J ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b BIOGEN   (United States)

^c SERONO PHARMACEUTICAL RES INSTITUTE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE RECEPTOR; IMMUNOGLOBULIN G; LYMPHOTOXIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; CELL MATURATION; CONTROLLED STUDY; DENDRITIC CELL; LYMPHOCYTE TRANSFER; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCID MOUSE; SPLEEN; SPLEEN CELL; T LYMPHOCYTE;

ANIMALS; B-LYMPHOCYTES; CELL DIFFERENTIATION; DENDRITIC CELLS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IMMUNOHISTOCHEMISTRY; LYMPHOTOXIN BETA RECEPTOR; LYMPHOTOXIN-ALPHA; MICE; MICE, SCID; MICROSCOPY, CONFOCAL; PHENOTYPE; RECEPTORS, TUMOR NECROSIS FACTOR; SIGNAL TRANSDUCTION; SPLEEN; T-LYMPHOCYTES; TRANSPLANTATION, ISOGENEIC;

EID: 0032489912     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.187.7.997     Document Type: Article

References (37)

1. Cormack, D.H. 1987. Introduction to Histology. J.B. Lippincot Company, Philadelphia. 10:255-261.
2. Paul, W.E. 1993. Fundamental Immunology. Raven Press, NY. 165-168.
3. Goodnow, C.C., J.G. Cyster, S.B. Hartley, S.E. Bell, M.P. Cooke, J.I. Healy, S. Akkaraju, J.C. Rathmell, S.L. Pogue, and K.P. Shokat. 1995. Self-tolerance checkpoints in B lymphocyte development. Adv. Immunol. 59:279-368.
4. Kuppers, R., M. Zhao, M.L. Hansmann, and K. Rajewsky. 1993. Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections. EMBO (Eur. Mol. Biol. Organ.) J. 12:4955-4967.
5. MacLennan, I.C. 1994. Germinal centers. Annu. Rev. Immunol. 12:117-139.
6. Kraal, G. 1992. Cells in the marginal zone of the spleen. Int. Rev. Cytol. 132:31-74.
7. Steinman, R.M., M. Pack, and K. Inaba. 1997. Dendritic cells in the T-cell areas of lymphoid organs. Immunol. Rev. 156:25-37.
8. Dijkstra, C.D., E.W. Kamperdijk, and E.A. Dopp. 1984. The ontogenic development of the follicular dendritic cell. An ultrastructural study by means of intravenously injected horse-radish peroxidase. Cell Tissue Res. 236:203-206.
9. Liu, Y.J., G. Grouard, O. de Bouteiller, and J. Banchereau. 1996. Follicular dendritic cells and germinal centers. Int. Rev. Cytol. 166:139-179.
10. Gretz, J.E., E.P. Kaldjian, A.O. Anderson, and S. Shaw. 1996. Sophisticated strategies for information encounter in the lymph node: the reticular network as a conduit of soluble information and a highway for cell traffic. J. Immunol. 157: 495-499.
11. Chilosi, M., M. Lestani, A. Benedetti, L. Montagna, S. Pedron, A. Scarpa, F. Menestrina, S. Hirohashi, G. Pizzolo, and G. Semenzato. 1993. Constitutive expression of tenascin in T-dependent zones of human lymphoid tissues. Am. J. Pathol. 143:1348-1355.
12. van den Berg, T.K., M. van der Ende, E.A. Dopp, G. Kraal, and C.D. Dijkstra. 1993. Localization of β1 integrins and their extracellular ligands in human lymphoid tissues. Am. J. Pathol. 143:1098-1110.
13. Castanos-Velez, E., P. Biberfeld, and M. Patarroyo. 1995. Extracellular matrix proteins and integrin receptors in reactive and non-reactive lymph nodes. Immunology. 86:270-278.
14. De Togni, P., J. Goellner, N.H. Ruddle, P.R. Streeter, A. Fick, S. Manathasan, S.C. Smith, R. Carlson, L.P. Shornick, J. Strauss-Schoenberger, et al. 1994. Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin. Science. 264:703-707.
15. Koni, P.A., R. Sacca, P. Lawton, J.L. Browning, N.H. Ruddle, and R.A. Flavell. 1997. Distinct roles in lymphoid organogenesis for lymphotoxins α and β revealed in lymphotoxin β-deficient mice. Immunity. 6:491-500.
16. Le Hir, M., H. Bluethmann, M.H. Kosco-Vilbois, M. Muller, F. di Padova, M. Moore, B. Ryffel, and H.P. Eugster. 1996. Differentiation of follicular dendritic cells and full antibody responses require tumor necrosis factor receptor-1 signaling. J. Exp. Med. 183:2367-2372.
17. Pasparakis, M., L. Alexopoulou, V. Episkopou, and G. Kollias. 1996. Immune and inflammatory responses in TNFα-deficient mice: a critical requirement for TNFα in the formation of primary B cell follicles, follicular dendritic cell networks, and germinal centers, and in the maturation of the humoral immune response. J. Exp. Med. 184:1397-1411.
18. Ettinger, R., J.L. Browning, S.A. Michie, W. van Ewijk, and H.O. McDevitt. 1996. Disrupted splenic architecture, but normal lymph node development in mice expressing a soluble lymphotoxin-β receptor-IgG1 fusion protein. Proc. Natl. Acad. Sci. USA. 93:13102-13107.
19. Rennert, P.D., J.L. Browning, R. Mebius, F. Mackay, and P.S. Hochman. 1996. Surface lymphotoxin α/β complex is required for the development of peripheral lymphoid organs. J. Exp. Med. 184:1999-2006.
20. Mackay, F., G.R. Majeau, P. Lawton, P.S. Hochmann, and J.L. Browning. 1997. Lymphotoxin but not tumor necrosis factor functions to maintain splenic architecture and humoral responsiveness in adult mice. Eur. J. Immunol. 27:2033-2042.
21. Kapasi, Z.F., G.F. Burton, L.D. Shultz, J.G. Tew, and A.K. Szakal. 1993. Induction of functional follicular dendritic cell development in severe combined immunodeficiency mice. Influence of B and T cells. J. Immunol. 150:2648-2658.
22. Yoshida, K., T.K. van den Berg, and C.D. Dijkstra. 1994. The functional state of follicular dendritic cells in severe combined immunodeficient (SCID) mice: role of the lymphocytes. Eur. J. Immunol. 24:464-468.
23. Yoshida, K., M. Kaji, T. Takahashi, T.K. van den Berg, and C.D. Dijkstra. 1995. Host origin of follicular dendritic cells induced in the spleen of SCID mice after transfer of allogeneic lymphocytes. Immunology. 84:117-126.
24. Crowe, P.D., T.L. VanArsdale, B.N. Walter, C.F. Ware, C. Hession, B. Ehrenfels, J.L. Browning, W.S. Din, R.G. Goodwin, and C.A. Smith. 1994. A lymphotoxin-β-specific receptor. Science. 264:707-710.
25. Kosco, M.H., E. Pflugfelder, and D. Gray. 1992. Follicular dendritic cell-dependent adhesion and proliferation of B cells in vitro J. Immunol. 148:2331-2339.
26. Inaba, K., M. Witmer-Pack, M. Inaba, K.S. Hathcock, H. Sakuta, M. Azuma, H. Yagita, K. Okumura, P.S. Linsley, S. Ikehara, et al. 1994. The tissue distribution of the B7-2 co-stimulator in mice: abundant expression on dendritic cells in situ and during maturation in vitro. J. Exp. Med. 180:1849-1860.
27. Kosco-Vilbois, M.H., and D. Scheidegger. 1995. Follicular dendritic cells: antigen retention, B cell activation, and cytokine production. Curr. Top. Microbiol. Immunol. 201:69-82.
28. Imazeki, N., A. Takeuchi, A. Senoo, and Y. Fuse. 1994. New monoclonal antibodies directed against mouse follicular dendritic cells. J. Histochem. Cytochem. 42:329-335.
29. Kraal, G., K. Schomagel, P.R. Streeter, B. Holzmann, and E.C. Butcher. 1995. Expression of the mucosal vascular addressin, MAdCAM-1, on sinus-lining cells in the spleen. Am. J. Pathol. 147:763-771.
30. Berlin, C., E.L. Berg, M.J. Briskin, D.P. Andrew, P.J. Kilshaw, B. Holzmann, I.L. Weissman, A. Hamann, and E.C. Butcher. 1993. α4β7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1. Cell. 74:185-195.
31. Ni, J., A.G. Porter, and D. Hollander. 1995. β7 integrins and other cell adhesion molecules are differentially expressed and modulated by TNFβ in different lymphocyte populations. Cell. Immunol. 161:166-172.
32. Melani, C., A. Silvani, G. Parmiani, and M.P. Colombo. 1993. Lymphotoxin gene expression by melanocytes and melanoma cell lines and persistence of unspliced mRNA. FEBS Lett. 335:114-118.
33. Ware, C.F., P.D. Crowe, M.H. Grayson, M.J. Androlewicz, and J.L. Browning. 1992. Expression of surface lymphotoxin and tumor necrosis factor on activated T, B, and natural killer cells. J. Immunol. 149:3881-3888.
34. Millet, I., and N.H. Ruddle. 1994. Differential regulation of lymphotoxin (LT), lymphotoxin-β (LT-β), and TNF-α in murine T cell clones activated through the TCR. J. Immunol. 152:4336-4346.
35. Worm, M., and R.S. Geha. 1994. CD40 ligation induces lymphotoxin α gene expression in human B cells. Int. Immunol. 6:1883-1890.
36. Cerny, A., R.M. Zinkernagel, and P. Groscurth. 1988. Development of follicular dendritic cells in lymph nodes of B-cell-depleted mice. Cell Tissue Res. 254:449-454.
37. Fu, Y.X., H. Molina, M. Matsumoto, G. Huang, J. Min, and D.D. Chaplin. 1997. Lymphotoxin α (LTα) supports development of splenic follicular structure that is required for IgG responses. J. Exp. Med. 185:2111-2120.