Mitochondrial oxidative stress can lead to nuclear hypermutability

Mechanisms of Ageing and Development

Volumn 125, Issue 6, 2004, Pages 417-420

  Hartman, Phil ^a   Ponder, Rebecca ^a   Lo, Herng Hsiang ^b   Ishii, Naoaki ^c  

^a TEXAS CHRISTIAN UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^c TOKAI UNIVERSITY   (Japan)

Author keywords

8 oxo deoxyguanosine; 8 oxo dG; C. elegans; mev 1; Mutation; Oxidative stress; reactive oxygen species; ROS

Indexed keywords

DNA; REACTIVE OXYGEN METABOLITE;

ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DNA STRAND BREAKAGE; EMBRYO; HYPOXIA; MUTAGENESIS; MUTANT; MUTATION RATE; NONHUMAN; ONCOGENE; OXIDATIVE STRESS; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE; WILD TYPE;

AGING; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELL NUCLEUS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYGUANOSINE; DNA; DNA DAMAGE; DNA-BINDING PROTEINS; MITOCHONDRIA; MUTAGENESIS; MUTAGENS; MUTATION; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; TRANSCRIPTION FACTORS;

CAENORHABDITIS; CAENORHABDITIS ELEGANS;

EID: 2942615439     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2004.02.007     Document Type: Article

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