Purines and pain mechanisms: Recent developments

Current Opinion in Investigational Drugs

Volumn 6, Issue 1, 2005, Pages 65-75

  Liu, Xue Jun ^a   Salter, Michael W ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Adenosine; ATP; Clinical trial; Microglia; Neuropathic pain; P2X receptors; P2Y receptors

Indexed keywords

2 METHYLTHIOADENOSINE TRIPHOSPHATE; 2',3' O (2,4,6 TRINITROPHENYL)ADENOSINE 5 TRIPHOSPHATE; 2',3' O (4 BENZOYLBENZOYL)ADENOSINE 5' TRIPHOSPHATE; A 317491; ADENOSINE; ADENOSINE A1 RECEPTOR; ADENOSINE DERIVATIVE; ADENOSINE DIPHOSPHATE; ADENOSINE RECEPTOR; ADENOSINE TRIPHOSPHATE; ALPHA,BETA METHYLENEADENOSINE TRIPHOSPHATE; G PROTEIN COUPLED RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE P38; PURINE DERIVATIVE; PURINE P2 RECEPTOR; PURINE P2X RECEPTOR BLOCKING AGENT; PURINE P2X2 RECEPTOR; PURINE P2X3 RECEPTOR; PURINE P2X4 RECEPTOR; PURINE P2X7 RECEPTOR; PURINE P2Y1 RECEPTOR; PURINE P2Y2 RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; PURINERGIC RECEPTOR STIMULATING AGENT; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID; RECEPTOR SUBTYPE; SURAMIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; URIDINE DIPHOSPHATE; URIDINE TRIPHOSPHATE;

ANALGESIC ACTIVITY; CENTRAL NERVOUS SYSTEM; CHRONIC PAIN; CLINICAL TRIAL; DISEASE MODEL; DRUG HALF LIFE; DRUG TARGETING; HUMAN; IC 50; INFLAMMATION; MICROGLIA; MOUSE MUTANT; NERVE INJURY; NEUROPATHIC PAIN; NONHUMAN; PAIN; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RECEPTOR BLOCKING; RECEPTOR INTRINSIC ACTIVITY; RECEPTOR UPREGULATION; REVIEW; SENSORY NERVE CELL; SIGNAL TRANSDUCTION;

ANIMALS; CLINICAL TRIALS; HUMANS; PAIN; PURINES; RECEPTORS, PURINERGIC; RECEPTORS, PURINERGIC P1; RECEPTORS, PURINERGIC P2;

EID: 12544250724     PISSN: 14724472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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