[3H]A-317491, a novel high-affinity non-nucleotide antagonist that specifically labels human P2X2/3 and P2X3 receptors

Journal of Pharmacology and Experimental Therapeutics

Volumn 310, Issue 1, 2004, Pages 407-416

  Jarvis, Michael F ^a,c   Bianchi, Bruce ^a   Uchic, John T ^a   Cartmell, Jayne ^a   Lee, Chih Hung ^a   Williams, Michael ^a,b   Faltynek, Connie ^a  

^a ABBOTT LABORATORIES   (United States)

^b CEPHALON INC   (United States)

^c R4PM AP9A/2 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHYLTHIOADENOSINE TRIPHOSPHATE; 2,3 O (4 BENZOYLBENZOYL)ADENOSINE TRIPHOSPHATE; A 317344; A 317491; ADENOSINE TRIPHOSPHATE DERIVATIVE; ALPHA,BETA METHYLENEADENOSINE TRIPHOSPHATE; APYRASE; CALCIUM ION; CIBACRON BLUE F3GA; DIADENOSINE POLYPHOSPHATE; PURINE P2X1 RECEPTOR; PURINE P2X2 RECEPTOR; PURINE P2X3 RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID; RADIOLIGAND; SURAMIN; TRITIUM; UNCLASSIFIED DRUG; A-317491; CALCIUM; PHENOL DERIVATIVE; POLYCYCLIC HYDROCARBON; PURINE P2 RECEPTOR; RECOMBINANT PROTEIN;

ARTICLE; ASTROCYTOMA CELL; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL MEMBRANE; CONTROLLED STUDY; DRUG BINDING SITE; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR DOWN REGULATION; CELL CULTURE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; RADIOASSAY;

CALCIUM; CELL MEMBRANE; HUMANS; PHENOLS; POLYCYCLIC COMPOUNDS; RADIOLIGAND ASSAY; RECEPTORS, PURINERGIC P2; RECOMBINANT PROTEINS; TRITIUM; TUMOR CELLS, CULTURED;

EID: 3042688015     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.064907     Document Type: Article

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