p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain

Journal of Neuroscience

Volumn 23, Issue 10, 2003, Pages 4017-4022

  Jin, Shan Xue ^a   Zhuang, Zhi Ye ^a   Woolf, Clifford J ^a   Ji, Ru Rong ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Dorsal root ganglion; Microglia; Neuropathic pain; p38 MAPK; Spinal cord; Spinal nerve ligation

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BIOLOGICAL MARKER; GLIAL FIBRILLARY ACIDIC PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; OX 42; UNCLASSIFIED DRUG; ENZYME INHIBITOR; IMIDAZOLE DERIVATIVE; PYRIDINE DERIVATIVE;

ALLODYNIA; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; IMMUNOHISTOCHEMISTRY; MALE; MICROGLIA; NERVE LIGATION; NEUROPATHIC PAIN; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL GANGLION; SPINAL NERVE; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; HYPERALGESIA; INTRASPINAL DRUG ADMINISTRATION; LIGATION; PAIN; PAIN ASSESSMENT; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SPINAL CORD; SPRAGUE DAWLEY RAT;

ANIMALS; BEHAVIOR, ANIMAL; ENZYME ACTIVATION; ENZYME INHIBITORS; GANGLIA, SPINAL; HYPERALGESIA; IMIDAZOLES; INJECTIONS, SPINAL; LIGATION; MALE; MICROGLIA; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PAIN; PAIN MEASUREMENT; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD; SPINAL NERVES;

EID: 0037705314     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-10-04017.2003     Document Type: Article

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