Cell type-specific ATP-activated responses in rat dorsal root ganglion neurons

British Journal of Pharmacology

Volumn 126, Issue 2, 1999, Pages 429-436

  Ueno, Shinya ^c   Tsuda, Makoto ^a   Iwanaga, Toshihiko ^b   Inoue, Kazuhide ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c FUKUOKA UNIVERSITY   (Japan)

Author keywords

ATP; Capsaicin; Dorsal root ganglia; In situ hybridization; P2X; Pain; Patch clamp

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALPHA,BETA METHYLENEADENOSINE TRIPHOSPHATE; CAPSAICIN; MESSENGER RNA; PURINE P2X RECEPTOR; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID; RECEPTOR SUBUNIT; SURAMIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL TYPE; CONTROLLED STUDY; IN SITU HYBRIDIZATION; MEMBRANE CURRENT; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL GANGLION; VOLTAGE CLAMP;

ADENOSINE TRIPHOSPHATE; ANIMALS; CAPSAICIN; DOSE-RESPONSE RELATIONSHIP, DRUG; GANGLIA, SPINAL; IN SITU HYBRIDIZATION; MALE; MEMBRANE POTENTIALS; NEURONS; PATCH-CLAMP TECHNIQUES; RATS; RATS, WISTAR; RECEPTORS, PURINERGIC P2; RNA, MESSENGER;

EID: 0032930328     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702319     Document Type: Article

References (28)

1. Bean, B.P. (1990). ATP-activated channels in rat and bullfrog sensory neurons: concentration dependence and kinetics. J. Neurosci., 10, 1-10.
2. Bo, X., Zhang, Y., Nassar, M., Burnstock, G. & Schoepfer, R. (1995). A P2X purinoceptor cDNA conferring a novel pharmacological profile. FEBS Lett., 375, 129-133.
3. Buell, G., Lewis, C., Collo, G., North, R.A. & Suprenant, A. (1996). An antagonist-insensitive P-2x receptor expressed in epithelial and brain. EMBO J., 15, 55-62.
4. Caterina, M.J., Schumacher, M.A., Tominaga, M., Rosen, T.A., Levine, J.D. & Julius, D. (1997). The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature, 389, 816-824.
5. Chen, C.C., Akopian, A.N., Sivilotti, L., Colquhoun, D., Burnstock, G. & Wood, J.N. (1995). A P2X purinoceptor expressed by a subset of sensory neurons. Nature, 377, 428-431.
6. Collo, G., North, R.A., Kawashima, E., Merlo-Pich, E., Neidhart, S., Surprenant, A. & Buell, G. (1996). Cloning of P2X5 and P2X6 receptors and the distribution and properties of an extended family of ATP-gated ion channels. J. Neurosci., 16, 2495-2507.
7. 2+ -dependent modulation of ATP-gated P2X receptors in nociceptors. Neuropharmacol., 36, 1303-1308.
8. Cook, S.P., Vulchanova, L., Hargreaves, K.M., Elde, R. & Mccleskey, E.W. (1997b). Distinct ATP receptors on pain-sensing and stretch-sensing neurons. Nature, 387, 505-508.
9. Hamill, O.P., Marty, A., Neher, E., Sakmann, B. & Sigworth, F.J. (1981). Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch., 391, 85-100.
10. Harper, A.A. & Lawson, S.N. (1985). Conduction velocity is related to morphological cell type in rat dorsal root ganglion neurones. J. Physiol., 359, 31-46.
11. Holzer, P. (1991). Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons. Pharmacol. Rev., 43, 143-201.
12. Jahr, C.E. & Jessell, T.M. (1983). ATP excites a subpopulation of rat dorsal horn neurones. Nature, 304, 730-733.
13. Khakh, B.S., Humphrey, P.P. & Suprenant, A. (1995). Electrophysiological properties of P2X-purinoceptors in rat superior cervical, nodose and guinea-pig coeliac neurones. J. Physiol., 484, 385-395.
14. Krishtal, O.A., Marchenko, S.M., Obukhov, A.G. & Volkova, T.M. (1988). Receptors for ATP in rat sensory neurones: the structure-function relationship for ligands. Br. J. Pharmacol., 95, 1057-1062.
15. Krishtal, O.A., Marchenko, S.M. & Pidoplichko, V.I. (1983). Receptor for ATP in the membrane of mammalian sensory neurones. Neurosci. Lett., 35, 41-45.
16. Lewis, C., Neidhart, S., Holy, C., North, R.A., Buell, G. & Suprenant, A. (1995). Coexpression of P2X(2) and P2X(3) receptor subunits can account for ATP-gated currents in sensory neurons. Nature, 377, 432-435.
17. Robertson, S.J., Rae, M.G., Rowan, E.G. & Kennedy, C. (1996). Characterization of a P2X-purinoceptor in cultured neurons of the rat dorsal root ganglia. Br. J. Pharmacol., 118, 951-956.
18. Seguela, P., Haghighi, A., Soghomonian, J.J. & Cooper, E. (1996). A novel neuronal P2x ATP receptor ion channel with widespread distribution in the brain. J. Neurosci., 16, 448-455.
19. Simone, D.A., Baumann, T.K. & Lamotte, R.H. (1989). Dose-dependent pain and mechanical hyperalgesia in humans after intradermal injection of capsaicin. Pain, 38, 99-107.
20. Soto, F., Garcia-Guzman, M., Gomez-Hernandez, J.M., Hollmann, M., Karschin, C. & Stuhmer, W. (1996). P2X4: an ATP-activated ionotropic receptor cloned from rat brain. Proc. Natl. Acad. Sci. U.S.A., 93, 3684-3688.
21. Soto, F., Garcia-Guzman, M. & Stuhmer, W. (1997). Cloned ligand-gated channels activated by extracellular ATP (P2X receptors). J. Memb. Biol., 160, 91-100.
22. Surprenant, A., Buell, G. & North, R.A. (1995). P2X receptors bring new structure to ligand-gated ion channels. Trends. Neurosci., 18, 224-229.
23. Thomas, S., Virginio, C., North, R.A. & Surprenant, A. (1998). The antagonist trinitrophenyl-ATP reveals co-existence of distinct P2X receptor channels in rat nodose neurons. J. Physiol., 509, 411-417.
24. Ueno, S., Bracamontes, J., Zorumski, C., Weiss, D.S. & Steinbach, J.H. (1997). Bicuculline and gabazine are allosteric inhibitors of channel opening of the GABAA receptor. J. Neurosci., 17, 625-634.
25. 2+ influx through recombinant P2X receplor in C6BU-I cells. Br. J. Pharmacol., 124, 1484-1490.
26. Virginio, C., North, R.A. & Surprenant, A. (1998). Calcium permeability and block at homomeric and heteromeric P2X2 and P2X3 receptors, and P2X receptors in nodose neurones. J. Physiol. (Lond.), 510, 27-35.
27. Vulchanova, L., Arvidsson, U., Riedl, M., Wang, J., Buell, G., Surprenant, A., North, R.A & Elde, R. (1996). Differential distribution of two ATP-gated channels (P2X receptors) determined by immunocytochemistry. Proc. Natl. Acad. Sci. U.S.A., 93, 8063-8067.
28. Vulchanova, L., Reidl, M.S., Shuster, S.J., Buell, G., Surprenant, A., North, R.A. & Elde, R. (1997). Immunohistochemical study of the P2X2 and P2X3 receptor subunits in rat and monkey sensory neurons and their central terminals. Neuropharmacol., 36, 1229-1242.