Inhibition of N-Type Voltage-Activated Calcium Channels in Rat Dorsal Root Ganglion Neurons by P2Y Receptors Is a Possible Mechanism of ADP-Induced Analgesia

Journal of Neuroscience

Volumn 24, Issue 4, 2004, Pages 797-807

  Gerevich, Zoltan ^a   Borvendeg, Sebestyen J ^a   Schröder, Wolfgang ^b   Franke, Heike ^a   Wirkner, Kerstin ^a   Nörenberg, Wolfgang ^a   Fürst, Susanna ^c   Gillen, Clemens ^b   Illes, Peter ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b GRÜNENTHAL GMBH   (Germany)

^c SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

Analgesia; ATP; Calcium channel; Dorsal root ganglion; P2Y receptor; Patch clamp

Indexed keywords

2' DEOXY 6 N METHYLADENOSINE 3',5' BISPHOSPHATE; 2' DEOXY 6 N METHYLADENOSINE 3',5' BISPHOSPHATE TETRAAMMONIUM; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CALCIUM CHANNEL N TYPE; CALCIUM ION; GLUTAMIC ACID; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (2 THIODIPHOSPHATE); GUANYLYLIMIDODIPHOSPHATE; OMEGA CONOTOXIN GVIA; PURINE P2Y RECEPTOR; PURINE P2Y1 RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; PYRIDOXAL 5 PHOSPHATE; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID; TETRAPENTYLAMMONIUM; UNCLASSIFIED DRUG; URIDINE TRIPHOSPHATE;

AMINO ACID METABOLISM; ANALGESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CONCENTRATION RESPONSE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DRUG POTENCY; ENZYME DEGRADATION; IMMUNOCYTOCHEMISTRY; INHIBITION KINETICS; MEMBRANE CURRENT; NEWBORN; NOCICEPTION; NONHUMAN; PATCH CLAMP; POTASSIUM TRANSPORT; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; RECEPTOR BINDING; RECEPTOR BLOCKING; SPINAL CORD TRANSSECTION; SPINAL GANGLION; TAIL FLICK TEST; VOLTAGE CLAMP;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANALGESIA; ANALGESICS; ANIMALS; CALCIUM; CALCIUM CHANNELS, N-TYPE; CELLS, CULTURED; EXCITATORY POSTSYNAPTIC POTENTIALS; GANGLIA, SPINAL; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; GUANOSINE DIPHOSPHATE; INJECTIONS, SPINAL; NEURONS; PAIN; PATCH-CLAMP TECHNIQUES; POTASSIUM; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; RECEPTORS, PURINERGIC P2; THIONUCLEOTIDES;

EID: 0742322860     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4019-03.2004     Document Type: Article

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