Prolonged Culture of Telomerase-Immortalized Human Fibroblasts Leads to a Premalignant Phenotype

Cancer Research

Volumn 63, Issue 21, 2003, Pages 7147-7157

  Milyavsky, Michael ^a   Shats, Igor ^a   Erez, Neta ^a   Tang, Xiaohu ^a   Senderovich, Shai ^a   Meerson, Ari ^a   Tabach, Yuval ^a   Goldfinger, Naomi ^a   Ginsberg, Doron ^a   Harris, Curtis C ^b   Rotter, Varda ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; COMPLEMENTARY DNA; DOXORUBICIN; GENE PRODUCT; MYC PROTEIN; PROTEIN BMI1; PROTEIN P14; PROTEIN P16; PROTEIN P53; RETINOBLASTOMA PROTEIN; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE; UNCLASSIFIED DRUG;

ARTICLE; BMI1 GENE; CANCER CELL CULTURE; CELL DIVISION; CELL GROWTH; CELL IMMORTALIZATION; CELL PROLIFERATION; CELL TRANSFORMATION; CHROMOSOME STRUCTURE; CONTACT INHIBITION; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA DAMAGE; DNA DETERMINATION; ENZYME ANALYSIS; FIBROBLAST; GENE EXPRESSION REGULATION; GENE LOCUS; GENE OVEREXPRESSION; HTERT GENE; HUMAN; HUMAN CELL; INK4A GENE; MALIGNANT NEOPLASTIC DISEASE; ONCOGENE; ONCOGENE C MYC; ONCOGENE H RAS; PHENOTYPIC VARIATION; POPULATION DOUBLING; PRECANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENESCENCE; STATISTICAL SIGNIFICANCE; TELOMERE;

CELL DIVISION; CELL TRANSFORMATION, NEOPLASTIC; CONTACT INHIBITION; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA-BINDING PROTEINS; FIBROBLASTS; GENE SILENCING; GENES, P53; GENES, RAS; HUMANS; PRECANCEROUS CONDITIONS; RETINOBLASTOMA PROTEIN; RETROVIRIDAE; TELOMERASE; TIME FACTORS; TRANSDUCTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P14ARF;

EID: 10744219897     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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