Abolition of cyclin-dependent kinase inhibitor p16Ink4a and p21Cip1/Waf1 functions permits Ras-induced anchorage-independent growth in telomerase-immortalized human fibroblasts

Molecular and Cellular Biology

Volumn 23, Issue 8, 2003, Pages 2859-2870

  Wei, Wenyi ^a,c   Jobling, Wendy A ^a   Chen, Wen ^b   Hahn, William C ^b   Sedivy, John M ^a  

^a BROWN UNIVERSITY   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; PROTEIN P16; PROTEIN P21; PROTEIN P53; TELOMERASE; VIRUS DNA; VIRUS T ANTIGEN;

ANCHORAGE INDEPENDENT GROWTH; ARTICLE; CARCINOGENESIS; CELL FUNCTION; CELL IMMORTALIZATION; CELL LINE; EMBRYO; FIBROBLAST; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN TISSUE; MALIGNANT TRANSFORMATION; NONHUMAN; ONCOGENE H RAS; ONCOGENE MYC; ONCOGENE RAS; ONCOVIRINAE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIMIAN VIRUS; TUMOR SUPPRESSOR GENE;

ANTIGENS, POLYOMAVIRUS TRANSFORMING; CELL ADHESION; CELL DIVISION; CELL LINE, TRANSFORMED; CELL TRANSFORMATION, NEOPLASTIC; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; GENE TARGETING; GENES, MYC; GENES, P16; HUMANS; RAS PROTEINS; TELOMERASE;

DNA VIRUSES; ONCOVIRINAE; RODENTIA; SIMIAE; SIMIAN VIRUS 40;

EID: 0037384852     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.23.8.2859-2870.2003     Document Type: Article

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