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Volumn 2, Issue 23, 2004, Pages 3409-3424

Multivalency in supramolecular chemistry and nanofabrication

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; CONCENTRATION (PROCESS); ENZYME IMMOBILIZATION; NANOTECHNOLOGY; REACTION KINETICS; SELF ASSEMBLY; SURFACE PROPERTIES; THERMODYNAMIC PROPERTIES;

EID: 10644280152     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/b413971b     Document Type: Review
Times cited : (438)

References (145)
  • 36
    • 10644257070 scopus 로고    scopus 로고
    • note
    • The term "intramolecular" is used here to indicate the formation of an interaction between two species between which such an interaction already existed; "intermolecular" indicates the formation of an interaction between two unlinked species.
  • 52
    • 0032531947 scopus 로고    scopus 로고
    • Kramer and Karpen have employed divalent guests tethered by a 20 kD PEG polymer for multivalent complexation of a protein, see:R. H. Kramer and J. W. Karpen, Nature, 1998, 395, 710-713.
    • (1998) Nature , vol.395 , pp. 710-713
    • Kramer, R.H.1    Karpen, J.W.2
  • 64
    • 10644289911 scopus 로고    scopus 로고
    • note
    • (ΔSintra-ΔSinter)/R See: ref. 44.
  • 80
    • 10644262741 scopus 로고    scopus 로고
    • note
    • mono). However, care should be taken in the analysis of the enthalpy data as secondary interactions between tethers may hamper correct interpretation, see ref. 1.
  • 82
    • 10644276761 scopus 로고    scopus 로고
    • note
    • Also all the examples in Section 3 can be analyzed in terms of pure multivalency.
  • 83
    • 10644286196 scopus 로고    scopus 로고
    • note
    • Vancomycin is an important member of the group of glycopeptide antibiotics that are active against gram-positive bacteria. The interest in vancomycin dimers stems from the different activities of these dimers towards bacteria, some of which have grown resistant to monomeric vancomycin by replacement of the carboxy-terminal DΑDΑ sequences at their cell walls - one of the main anchoring points for vancomycin - with DΑLac.
  • 87
    • 10644287053 scopus 로고    scopus 로고
    • note
    • -1 gives EM = 74 mM.
  • 88
    • 10644236767 scopus 로고    scopus 로고
    • note
    • 7 s or 200 days.
  • 94
    • 10644278468 scopus 로고    scopus 로고
    • note
    • Only the bis(dibenzylammonium) dication spaced by the poly(ethylene glycol) tether gave relatively low association constants compared to the intrinsic interaction. This was attributed to partial intramolecular complexation of the cations by the poly(ethylene glycol) tether.
  • 120
    • 0037448906 scopus 로고    scopus 로고
    • Williams et al. have shown that a high effective concentration of functionalities in lipid bilayers can give rise to complexes that cannot be achieved in solution. The systematic variation of the concentration of metal-chelating guests at lipid bilayer membrane surfaces revealed the presence of an extraordinary 4 : 1 receptor:copper(II) complex at high concentrations of guest functionalities in the bilayer. The formation of this complex was not observed in solution. See: E. L. Doyle, C. A. Hunter, H. C. Philips, S. J. Webb and N. H. Williams, J. Am. Chem. Soc., 2003, 125, 4593-4599.
    • (2003) J. Am. Chem. Soc. , vol.125 , pp. 4593-4599
    • Doyle, E.L.1    Hunter, C.A.2    Philips, H.C.3    Webb, S.J.4    Williams, N.H.5
  • 123
    • 10644258450 scopus 로고    scopus 로고
    • note
    • Similarly, relatively low effective molarities have also been observed for the interaction of monoclonal antibodies with a SAM: see refs. 83 and 95.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.