Using surface plasmon resonance to study the binding of vancomycin and its dimer to self-assembled monolayers presenting D-Ala-D-Ala [17]

Journal of the American Chemical Society

Volumn 121, Issue 11, 1999, Pages 2629-2630

  Rao, Jianghong ^a   Yan, Lin ^a   Xu, Bing ^a   Whitesides, George M ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE DERIVATIVE; ANTIBIOTIC AGENT; LIGAND; POLYPEPTIDE; VANCOMYCIN;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; BACTERIAL CELL WALL; BINDING AFFINITY; BINDING KINETICS; DRUG BINDING; DRUG BINDING SITE; GRAM POSITIVE BACTERIUM; LETTER; NONHUMAN; SURFACE PLASMON RESONANCE;

EID: 0033599497     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9838763     Document Type: Letter

References (23)

1. (a) Perkins, H. R. Biochem. J. 1969, 111, 195.
2. (b) Nieto, M.; Perkins, H. R. Biochem. J. 1971, 124, 845.
3. Wright, G. D.; Walsh, C. T. Acc. Chem. Res. 1992, 25, 468.
4. Westwell, M. S.; Bardsley, B.; Dancer, R. J.; Try, A. C.; Williams, D. H. J. Chem. Soc., Chem. Commun. 1996, 589.
5. Mackay, J. P.; Gerhard, U.; Beauregard, D. A.; Maplestone, R. A.; Williams, D. H. J. Am. Chem. Soc. 1994, 116, 4573.
6. Mackay, J. P.; Gerhard, U.; Beauregard, D. A.; Westwell, M. S.; Searle, M. S.; Williams, D. H. J. Am. Chem. Soc. 1994, 116, 4581.
7. Loll, P. J.; Bevivino, A. E.; Korty, B. D.; Axelsen, P. H. J. Am. Chem. Soc. 1997, 119, 1516.
8. Sundram, U. N.; Griffin, J. H.; Nicas, T. I. J. Am. Chem. Soc. 1996, 118, 13107.
9. Bugg, T. D.; Wright, G. D.; Dutka-Malen, S.; Arthur, M.; Courvalin, P.; Walsh, C. T. Biochemistry 1991, 30, 10408.
10. Chu, Y.-H.; Whitesides, G. M. J. Org. Chem. 1992, 57, 3524.
11. Popieniek, P. H.; Pratt, R. F. J. Am. Chem. Soc. 1991, 113, 2264.
12. Cooper, M. A.; Williams, D. H.; Cho, Y. H. J. Chem. Soc. Chem. Commun. 1997, 1625.
13. Rao, J.; Whitesides, G. M. J. Am. Chem. Soc. 1997, 119, 10286.
14. (a) Mrksich, M.; Grunwell, J. R.; Whitesides, G. M. J. Am. Chem. Soc. 1995, 117, 12009.
15. (b) Mrksich, M.; Sigal, G. B.; Whitesides, G. M. Langmuir 1995, 11, 4383.
16. (c) Sigal, G. B.; Bamdad, C.; Barberis, A.; Strominger, J.; Whitesides, G. M. Anal. Chem. 1996, 68, 490.
17. α-ACKDADA (pH = 10).
18. We did not directly measure the surface density of L* group. We assumed that the interchain anhydride at the surface completely reacted with the L groups under our experimental conditions.
19. For all of the Scatchard analyses in this paper, the bulk effects were subtracted from the data used.
20. Popieniek, P. H.; Pratt, R. F. Anal. Biochem. 1987, 165, 108.
21. Williams, D. H.; Maguire, A. J.; Tsuzuki, W.; Westwell, M. S. Science 1998, 280, 711.
22. The observation of a smaller value of RU and slower dissociation rate with the addition of 150 μM of AcL reflected the blocking of the monovalent binding by the large excess of AcL in the solution.
23. α-ACKDADA (2 mg/mL) in 25 mM phosphate buffer at pH 8.1 for 30 min. Lahiri, J.; Isaacs, L.; Tien, J.; Whitesides, G. M. Anal. Chem. 1999, 71, 777.