On the Nature of the Multivalency Effect: A Thermodynamic Model

Journal of the American Chemical Society

Volumn 125, Issue 52, 2003, Pages 16271-16284

  Kitov, Pavel I ^a   Bundle, David R ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

MULTIVALENCY EFFECT;

BINDING ENERGY; CARBOHYDRATES; CHEMICAL BONDS; COMPLEXATION; CONFORMATIONS; ENTROPY; FREE ENERGY; MATHEMATICAL MODELS; THERMODYNAMICS;

BIOCHEMISTRY;

CARBOHYDRATE; CELL SURFACE RECEPTOR; LIGAND; OLIGOSACCHARIDE; VEROTOXIN; VEROTOXIN 1;

ARTICLE; BINDING AFFINITY; BINDING SITE; BIOLOGICAL MODEL; CHEMICAL BINDING; CHEMICAL INTERACTION; CHEMICAL MODEL; CHEMISTRY; COMPLEX FORMATION; DILUTION; ENERGY; ENTROPY; IMMOBILIZATION; KINETICS; LIGAND BINDING; METABOLISM; RECEPTOR BINDING; THERMODYNAMICS;

KINETICS; LIGANDS; MODELS, BIOLOGICAL; MODELS, CHEMICAL; OLIGOSACCHARIDES; RECEPTORS, CELL SURFACE; SHIGA-LIKE TOXIN I; THERMODYNAMICS;

EID: 0347694971     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja038223n     Document Type: Article

References (41)

1. (a) Lee, R. T.; Lee, Y. C. Glycoconjugate J. 2000. 17, 543-551.
2. (b) Mammen, M.; Choi, S. K.; Whitesides, G. M. Angew. Chem., Int. Ed. 1998, 37, 2755-2794.
3. (c) Lundquist, J. J.; Toone, E. J. Chem. Rev. 2002, 102, 555-578.
4. St. Hillaire, P. M.; Boyd, M. K.; Toone, E. J. Biochemistry 1994, 33, 14452-14463.
5. (a) Glick, G.; Knowles, J. R. J. Am. Chem. Soc. 1991, 113. 4701-4703.
6. (b) Glick, G. D.; Toogood, P. L.; Wiley, D. C.; Skehel, J. J.; Knowles. J. R. J. Biol. Chem. 1991, 266, 23660-23669.
7. (c). Sigal, G. B.; Mammen, M.: Dahmann, G.; Whitesides, G. M. J. Am. Chem. Soc. 1996, 118, 3789-3800.
8. (d) von Itzstein, M.; Wu, W.-Y.; Kok, G. B.: Pegg, M. S.; Dyason, J. C.; Jin, B.; Phan, T. V.; Smythe, M. L.; White, H. F.; Oliver, S. W.; Colman, P. M. ; Varghese, J. N.; Ryan, D. M.; Woods; J. M.; Bethell, R. C.; Hotham, V. J.; Cameron, J. M.; Penn, C. R. Nature 1993, 363, 418-423.
9. Sharon, N.; Ofek, I. Glycoconjugate J. 2000. 17. 659-664.
10. Kitov, P. I.; Sadowska, J. M.; Mulvey, G.; Armstrong, G. D.; Ling, H.; Pannu, N. S.; Read, R. J.; Bundle, D. R. Nature 2000, 403, 669-672.
11. Jencks, W. P. Proc. Natl. Acad. Sci. U.S.A. 1981, 78, 4046-50.
12. Zhang, Z.; Merritt, E. A.; Ahn, M.; Roach, C.; Hou, Z.; Verlinde, C. L. M. J.; Hol, W. G. J.; Fan, E. J. Am. Chem. Soc. 2002, 124, 12991-12998.
13. Kitov, P. I.; Shimizu, H.; Homans, S. W.; Bundle, D. R. J. Am. Chem. Soc. 2003, 125, 3284-3294.
14. (a) Helg, A.; Mueller, M. S.; Joss, A.; Poltl-Frank, F.; Stuart, F.; Robinson, J. A.; Pluschke, G. J. Immunol. Methods 2003, 276 (1-2), 19-31.
15. (b) Mattes, M. J. J. Immunol. Methods 1997, 202, 97-101.
16. Karush, F. The affinity of antibody: range, variability and the role of multivalence. In Comprehensive Immunology. Immunoglobulins. Plenum Press: New York. 1978: pp 85-116.
17. (a) Dimick, S. M.; Powell, S. C.; McMahon, S. A.; Moothoo, D. N.; Naismith, J. H.; Toone, E. J. J. Am. Chem. Soc. 1999. 121. 10286-10296.
18. (b) Corbell, J. B.; Lundquist, J. J.; Toone, E. J., Tetrahedron: Asymmetry 2000, 11, 95-111.
19. (c) Lundquist, J. J.; Debenham, S. D.; Toone, E. J. J. Org. Chem. 2000, 65, 8245-8250.
20. (d) Dato, T. K.; Roy, R.; Das, S. K.; Oscarson, S.; Brewer, C. F., Biol. Chem. 2000, 275, 14223-14230.
21. (c) Dam, T. K.; Brewer, C. F.; Das, S. K.; Roy, R. Glycobiology 2001, 11, 189.
22. Chakrabarti, C. G.; De, K. Internat. J. Math. Math. Sci. 2000, 23(4), 243-251.
23. Rao, J.; Lahiri, J.; Isaacs, L.; Weis, R. M.; Whitesides, G. M. Science 1998. 280. 708-711.
24. Burke, S. D.; Zhao, Q.; Schuster, M. C.; Kiessling, L. L. J. Am. Chem. Soc. 2000, 122, 4518-4519.
25. (a) Mammen, M.; Shakhnovich, E. I.; Whitesides, G. M., J. Org. Chem. 1998, 63, 3168-3175.
26. (b) Burkhaller, N. F.; Dimick, S. M.; Toone, E. J. In Protein-Carbohydrate Interaction: Fundamental Considerations. Carbohydrates in Chemistry and Biology: Ernst, G. W. H. B., Sinay, P., Eds.: Wiley-VCH: New York. 2000: pp 865-914.
27. Ling, H.; Boodhoo, A.; Hazes, B.; Cummings, M. D.; Armstrong, G. D.; Brunton, J. L.; Read, R. J. Biochemistry 1998, 37, 1777-1788.
28. (a) Richardson, J. M.; Evans, P. D.; Homans, S. W.; Donohue-Rolfe, A. Nat. Struct. Biol. 1997, 4, 190-193.
29. (b) Kitova, E. N.; Kitov, P. I.: Bundle, D. R.; Klassen. J. S. Glycobiology 2001, 11, 605-611.
30. Soltyk, A.M.; MacKenzie, C.R.; Wolski, V.M.; Hirama, T.; Kitov, P.I.; Bundle, D. R.; Brunton, J. L. J. Biol. Chem, 2002, 277 (7). 5351-5359.
31. Kitov, P. I.; Bundle, D. R. J. Chem. Soc., Perkin Trans. 1 2001, 838-853.
32. Rao, V. S.; Perlin, A. S. Can. J. Chem. 1983, 61, 2688-2694.
33. Feldman, R. G.; Hamel, M. E.; Breukels, M. A.; Concepcion, N. F.; Anthony, B. F. J. Immunol. Methods 1994, 170 (1), 37-45.
34. (a) Vorberg, E.; Bundle, D. R. J. Immunol. Methods 1990, 132, 81-9.
35. (b) Sigurskjold, B. W.; Altman, E.; Bundle, D. R. Eur. J. Biochem. 1991, 197, 239-246.
36. Chang, K.-J.; Jacobs, S.; Cuatrecasas, P. Biochim. Biophys. Acta 1975, 406, 294-303.
37. Gewurz, H.; Zhang, X.-H.; Lint, T. F. Curr. Opin. Immun. 1995, 7, 54-64.
38. MacManus, D. A.; Vulfson, E. N. Carbohydr. Res. 1995, 279, 281-292.
39. Lakhmiri, R.; Lhoste, P.; Sinou, D. Synth. Commun. 1990, 20, 1551-1554.
40. Kieburg, C.; Dubber, M.; Lindhorst, T. K. Synth. Lett. 1997, 12, 1447-1449.
41. Calculated molecular weight. Due to isotopic distribution the highest peak in mass spectra of high-molecular weight compounds correlates better with molecular weight than with the mass of monoisotopic ion. Dell, A.; Morris, H. R.; Easton, R.; Haslam, S.; Panico, M.; Sutton-Smith, M.; Reason, A. J.; Khoo, K.-H. In Structural Analysis of Oligosaccharides: FAB-MS, ES-MS and MALDY-MS; Ernst, G. W. H. B., Sinay, P., Eds.; Wiley-VCH: New York, 2000; pp 865-914.