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Volumn 20, Issue 1, 2004, Pages 13-27

Progenitor cells in the adult pancreas

Author keywords

Development; Pancreas; Regeneration; Stem cell

Indexed keywords

ACINAR CELL; AGE; CELL DAMAGE; CELL DIFFERENTIATION; CELL MATURATION; CELL REGENERATION; EMBRYO CELL; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MEDICAL RESEARCH; MOLECULAR BIOLOGY; NONHUMAN; ORGANOGENESIS; PANCREAS ISLET BETA CELL; PHENOTYPE; PRIORITY JOURNAL; REVIEW; STEM CELL; STEM CELL TRANSPLANTATION;

EID: 1042268841     PISSN: 15207552     EISSN: None     Source Type: Journal    
DOI: 10.1002/dmrr.430     Document Type: Review
Times cited : (53)

References (182)
  • 1
    • 0037133163 scopus 로고    scopus 로고
    • Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model
    • Bjorklund LM, Sanchez-Pernaute R, Chung S, et al. Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model. Proc Natl Acad Sci USA 2002; 99: 2344-2349.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 2344-2349
    • Bjorklund, L.M.1    Sanchez-Pernaute, R.2    Chung, S.3
  • 2
    • 0029027780 scopus 로고
    • Developmental biology of the pancreas
    • Slack JMW. Developmental biology of the pancreas. Development 1995; 121: 1569-1580.
    • (1995) Development , vol.121 , pp. 1569-1580
    • Slack, J.M.W.1
  • 3
    • 0026518591 scopus 로고
    • Onset of cell-specific gene expression in the developing mouse pancreas
    • Gittes GK, Rutter WJ. Onset of cell-specific gene expression in the developing mouse pancreas. Proc Natl Acad Sci U S A 1992; 89: 1128-1132.
    • (1992) Proc. Natl. Acad. Sci. U S A , vol.89 , pp. 1128-1132
    • Gittes, G.K.1    Rutter, W.J.2
  • 4
    • 0030927342 scopus 로고    scopus 로고
    • The β cell transcription factors and development of the pancreas
    • Sander M, German MS. The β cell transcription factors and development of the pancreas. J Mol Med 1997; 75: 327-340.
    • (1997) J. Mol. Med. , vol.75 , pp. 327-340
    • Sander, M.1    German, M.S.2
  • 5
    • 0032860478 scopus 로고    scopus 로고
    • Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient mice
    • Harrison KA, Thaler J, Pfaff SL, Gu H, Kehrl JH. Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient mice. Nat Genet 1999; 23: 71-75.
    • (1999) Nat. Genet. , vol.23 , pp. 71-75
    • Harrison, K.A.1    Thaler, J.2    Pfaff, S.L.3    Gu, H.4    Kehrl, J.H.5
  • 6
    • 0032844643 scopus 로고    scopus 로고
    • Selective agenesis of the dorsal pancreas in mice lacking homeobox gene Hlxb9
    • Li H, Arber S, Jessell TM, Edlund H. Selective agenesis of the dorsal pancreas in mice lacking homeobox gene Hlxb9. Nat Genet 1999; 23: 67-70.
    • (1999) Nat. Genet. , vol.23 , pp. 67-70
    • Li, H.1    Arber, S.2    Jessell, T.M.3    Edlund, H.4
  • 7
    • 0029868156 scopus 로고    scopus 로고
    • PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum
    • Offield MF, Jetton TL, Labosky PA, et al. PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development 1996; 122: 983-995.
    • (1996) Development , vol.122 , pp. 983-995
    • Offield, M.F.1    Jetton, T.L.2    Labosky, P.A.3
  • 8
    • 0029950724 scopus 로고    scopus 로고
    • The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice
    • Ahlgren U, Jonsson J, Edlund H. The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice. Development 1996; 122: 1409-1416.
    • (1996) Development , vol.122 , pp. 1409-1416
    • Ahlgren, U.1    Jonsson, J.2    Edlund, H.3
  • 9
    • 0028869514 scopus 로고
    • Expression of murine STF-1, a putative insulin gene transcription factor, in β cells of pancreas, duodenal epthelium and pancreatic exocrine and endocrine progenitors during ontogeny
    • Guz Y, Montminy MR, Stein R, et al. Expression of murine STF-1, a putative insulin gene transcription factor, in β cells of pancreas, duodenal epthelium and pancreatic exocrine and endocrine progenitors during ontogeny. Development 1995; 121: 11-18.
    • (1995) Development , vol.121 , pp. 11-18
    • Guz, Y.1    Montminy, M.R.2    Stein, R.3
  • 12
    • 0034071348 scopus 로고    scopus 로고
    • The concentric structure of the developing gut is regulated by Sonic hedgehog derived from endodermal epithelium
    • Sukegawa A, Narita T, Kameda T, et al. The concentric structure of the developing gut is regulated by Sonic hedgehog derived from endodermal epithelium. Development 2000; 127: 1971-1980.
    • (2000) Development , vol.127 , pp. 1971-1980
    • Sukegawa, A.1    Narita, T.2    Kameda, T.3
  • 13
    • 0033916281 scopus 로고    scopus 로고
    • Hedgehog signals regulate multiple aspects of gastrointestinal development
    • Ramalho-Santos M, Melton DA, McMahon AP. Hedgehog signals regulate multiple aspects of gastrointestinal development. Development 2000; 127: 2763-2772.
    • (2000) Development , vol.127 , pp. 2763-2772
    • Ramalho-Santos, M.1    Melton, D.A.2    McMahon, A.P.3
  • 14
    • 0031260579 scopus 로고    scopus 로고
    • Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas
    • [published erratum appears in Curr Biol 1997; 7(12): R809]
    • Apelqvist A, Ahlgren U, Edlund H. Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas [published erratum appears in Curr Biol 1997; 7(12): R809]; CurrBiol 1997; 7: 801-804.
    • (1997) CurrBiol. , vol.7 , pp. 801-804
    • Apelqvist, A.1    Ahlgren, U.2    Edlund, H.3
  • 15
    • 0035112448 scopus 로고    scopus 로고
    • Key events of pancreas formation are triggered in gut endoderm by ectopic expression of pancreatic regulatory genes
    • Grapin-Botton A, Majithia AR, Melton DA. Key events of pancreas formation are triggered in gut endoderm by ectopic expression of pancreatic regulatory genes. Genes Dev 2001; 15: 444-454.
    • (2001) Genes Dev. , vol.15 , pp. 444-454
    • Grapin-Botton, A.1    Majithia, A.R.2    Melton, D.A.3
  • 16
    • 0034093614 scopus 로고    scopus 로고
    • Early mouse endoderm is patterned by soluble factors from adjacent germ layers
    • Wells JM, Melton DA. Early mouse endoderm is patterned by soluble factors from adjacent germ layers. Development 2000; 127: 1563-1572.
    • (2000) Development , vol.127 , pp. 1563-1572
    • Wells, J.M.1    Melton, D.A.2
  • 17
    • 0035914069 scopus 로고    scopus 로고
    • Liver organogenesis promoted by endothelial cells prior to vascular function
    • Matsumoto K, Yoshitomi H, Rossant J, Zaret KS. Liver organogenesis promoted by endothelial cells prior to vascular function. Science 2001; 294: 559-563.
    • (2001) Science , vol.294 , pp. 559-563
    • Matsumoto, K.1    Yoshitomi, H.2    Rossant, J.3    Zaret, K.S.4
  • 18
    • 0035913986 scopus 로고    scopus 로고
    • Induction of pancreatic differentiation by signals from blood vessels
    • Lammert E, Cleaver O, Melton D. Induction of pancreatic differentiation by signals from blood vessels. Science 2001; 294: 564-567.
    • (2001) Science , vol.294 , pp. 564-567
    • Lammert, E.1    Cleaver, O.2    Melton, D.3
  • 19
    • 0030681247 scopus 로고    scopus 로고
    • Notochord to endoderm signaling is required for pancreas development
    • Kim SK, Hebrok M, Melton DA. Notochord to endoderm signaling is required for pancreas development. Development 1997; 124: 4243-4252.
    • (1997) Development , vol.124 , pp. 4243-4252
    • Kim, S.K.1    Hebrok, M.2    Melton, D.A.3
  • 20
    • 2642589990 scopus 로고    scopus 로고
    • Notochord repression of endodermal Sonic hedgehog permits pancreas development
    • Hebrok M, Kim SK, Melton DA. Notochord repression of endodermal Sonic hedgehog permits pancreas development. Genes Dev 1998; 12: 1705-1713.
    • (1998) Genes Dev. , vol.12 , pp. 1705-1713
    • Hebrok, M.1    Kim, S.K.2    Melton, D.A.3
  • 21
    • 0035072545 scopus 로고    scopus 로고
    • A bipotential precursor population for pancreas and liver within the embryonic endoderm
    • Deutsch G, Jung J, Zheng M, Lora J, Zaret KS. A bipotential precursor population for pancreas and liver within the embryonic endoderm. Development 2001; 128: 871-881.
    • (2001) Development , vol.128 , pp. 871-881
    • Deutsch, G.1    Jung, J.2    Zheng, M.3    Lora, J.4    Zaret, K.S.5
  • 22
    • 0031020002 scopus 로고    scopus 로고
    • Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells
    • Ahlgren U, Pfaff SL, Jessell TM, Edlund T, Edlund H. Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells. Nature 1997; 385: 257-260.
    • (1997) Nature , vol.385 , pp. 257-260
    • Ahlgren, U.1    Pfaff, S.L.2    Jessell, T.M.3    Edlund, T.4    Edlund, H.5
  • 23
    • 0036730427 scopus 로고    scopus 로고
    • The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors
    • Kawaguchi Y, Cooper B, Gannon M, Ray M, MacDonald RJ, Wright CV. The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors. Nat Genet 2002; 32: 128-134.
    • (2002) Nat. Genet. , vol.32 , pp. 128-134
    • Kawaguchi, Y.1    Cooper, B.2    Gannon, M.3    Ray, M.4    MacDonald, R.J.5    Wright, C.V.6
  • 24
    • 0037795466 scopus 로고    scopus 로고
    • Human pancreatic precursor cells secrete FGF2 to stimulate clustering into hormone-expressing islet-like cell aggregates
    • Hardikar AA, Marcus-Samuels B, Geras-Raaka E, Raaka BM, Gershengorn MC. Human pancreatic precursor cells secrete FGF2 to stimulate clustering into hormone-expressing islet-like cell aggregates. Proc Natl Acad Sci USA 2003; 100: 7117-7122.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 7117-7122
    • Hardikar, A.A.1    Marcus-Samuels, B.2    Geras-Raaka, E.3    Raaka, B.M.4    Gershengorn, M.C.5
  • 25
    • 0037133681 scopus 로고    scopus 로고
    • Role for FGFR2IIIb-mediated signals in controlling pancreatic endocrine progenitor cell proliferation
    • Elghazi L, Cras-Meneur C, Czernichow P, Scharfmann R. Role for FGFR2IIIb-mediated signals in controlling pancreatic endocrine progenitor cell proliferation. Proc Natl Acad Sci U S A 2002; 99: 3884-3889.
    • (2002) Proc. Natl. Acad. Sci. U S A , vol.99 , pp. 3884-3889
    • Elghazi, L.1    Cras-Meneur, C.2    Czernichow, P.3    Scharfmann, R.4
  • 26
    • 0032991511 scopus 로고    scopus 로고
    • Signaling through fibroblast growth factor receptor 2b plays a key role in the development of the exocrine pancreas
    • Miralles F, Czernichow P, Ozaki K, Itoh N, Scharfmann R. Signaling through fibroblast growth factor receptor 2b plays a key role in the development of the exocrine pancreas. Proc Natl Acad Sci U S A 1999; 96: 6267-6272.
    • (1999) Proc. Natl. Acad. Sci. U S A , vol.96 , pp. 6267-6272
    • Miralles, F.1    Czernichow, P.2    Ozaki, K.3    Itoh, N.4    Scharfmann, R.5
  • 27
    • 0035694459 scopus 로고    scopus 로고
    • Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis
    • Bhushan A, Itoh N, Kato S, et al. Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis. Development 2001; 128: 5109-5117.
    • (2001) Development , vol.128 , pp. 5109-5117
    • Bhushan, A.1    Itoh, N.2    Kato, S.3
  • 28
    • 0033821515 scopus 로고    scopus 로고
    • Control of early development of the pancreas in rodents and humans: Implications of signals from the mesenchyme
    • [In Process Citation]
    • Scharfmann R. Control of early development of the pancreas in rodents and humans: implications of signals from the mesenchyme [In Process Citation]. Diabetologia 2000; 43: 1083-1092.
    • (2000) Diabetologia , vol.43 , pp. 1083-1092
    • Scharfmann, R.1
  • 29
    • 0035863135 scopus 로고    scopus 로고
    • Intercellular signals regulating pancreas development and function
    • Kim SK, Hebrok M. Intercellular signals regulating pancreas development and function. Genes Dev 2001; 15: 111-127.
    • (2001) Genes Dev. , vol.15 , pp. 111-127
    • Kim, S.K.1    Hebrok, M.2
  • 30
    • 0031738115 scopus 로고    scopus 로고
    • Transcribing pancreas
    • Edlund H. Transcribing pancreas. Diabetes 1998; 47: 1817-1823.
    • (1998) Diabetes , vol.47 , pp. 1817-1823
    • Edlund, H.1
  • 32
    • 0033606972 scopus 로고    scopus 로고
    • Notch signalling controls pancreatic cell differentiation
    • Apelqvist A, Li H, Sommer L, et al. Notch signalling controls pancreatic cell differentiation. Nature 1999; 400: 877-881.
    • (1999) Nature , vol.400 , pp. 877-881
    • Apelqvist, A.1    Li, H.2    Sommer, L.3
  • 33
    • 0035807902 scopus 로고    scopus 로고
    • A transcription factor regulatory circuit in differentiated pancreatic cells
    • Boj SF, Parrizas M, Maestro MA, Ferrer J. A transcription factor regulatory circuit in differentiated pancreatic cells. Proc Natl Acad Sci U S A 2001; 98: 14 481-14 486.
    • (2001) Proc. Natl. Acad. Sci. U S A , vol.98 , pp. 14481-14486
    • Boj, S.F.1    Parrizas, M.2    Maestro, M.A.3    Ferrer, J.4
  • 34
    • 0028149890 scopus 로고
    • Insulin-promoter-factor 1 is required for pancreas development in mice
    • Jonsson J, Carlsson L, Edlund T, Edlund H. Insulin-promoter-factor 1 is required for pancreas development in mice. Nature 1994; 371: 606-609.
    • (1994) Nature , vol.371 , pp. 606-609
    • Jonsson, J.1    Carlsson, L.2    Edlund, T.3    Edlund, H.4
  • 35
    • 0030914931 scopus 로고    scopus 로고
    • Pax6 is required for differentiation of glucagon-producing alpha-cells in mouse pancreas
    • St-Onge L, Sosa-Pineda B, Chowdhury K, Mansouri A, Gruss P. Pax6 is required for differentiation of glucagon-producing alpha-cells in mouse pancreas. Nature 1997; 387: 406-409.
    • (1997) Nature , vol.387 , pp. 406-409
    • St-Onge, L.1    Sosa-Pineda, B.2    Chowdhury, K.3    Mansouri, A.4    Gruss, P.5
  • 36
    • 1842330860 scopus 로고    scopus 로고
    • Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development
    • Sander M, Neubuser A, Kalamaras J, Ee HC, Martin GR, German MS. Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development. Genes Dev 1997; 11: 1662-1673.
    • (1997) Genes Dev. , vol.11 , pp. 1662-1673
    • Sander, M.1    Neubuser, A.2    Kalamaras, J.3    Ee, H.C.4    Martin, G.R.5    German, M.S.6
  • 37
    • 0030897629 scopus 로고    scopus 로고
    • The Pax4 gene is essential for differentiation of insulin-producing beta cells in the mammalian pancreas
    • Sosa-Pineda B, Chowdhury K, Torres M, Oliver G, Gruss P. The Pax4 gene is essential for differentiation of insulin-producing beta cells in the mammalian pancreas. Nature 1997; 386: 399-402.
    • (1997) Nature , vol.386 , pp. 399-402
    • Sosa-Pineda, B.1    Chowdhury, K.2    Torres, M.3    Oliver, G.4    Gruss, P.5
  • 38
    • 0031843386 scopus 로고    scopus 로고
    • Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic β-cells
    • Sussel L, Kalamaras J, Hratigan-O'Connor DJ, et al. Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic β-cells. Development 1998; 125: 2213-2221.
    • (1998) Development , vol.125 , pp. 2213-2221
    • Sussel, L.1    Kalamaras, J.2    Hratigan-O'Connor, D.J.3
  • 39
    • 0033844629 scopus 로고    scopus 로고
    • Ventral neural patterning by Nkx homeobox genes: Nkx6.1 controls somatic motor neuron and ventral interneuron fates
    • Sander M, Paydar S, Ericson J, et al. Ventral neural patterning by Nkx homeobox genes: Nkx6.1 controls somatic motor neuron and ventral interneuron fates. Genes Dev 2000; 14: 2134-2139.
    • (2000) Genes Dev. , vol.14 , pp. 2134-2139
    • Sander, M.1    Paydar, S.2    Ericson, J.3
  • 41
    • 0030886674 scopus 로고    scopus 로고
    • Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice
    • Naya FJ, Huang HP, Qiu Y, et al. Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice. Genes Dev 1997; 11: 2323-2334.
    • (1997) Genes Dev. , vol.11 , pp. 2323-2334
    • Naya, F.J.1    Huang, H.P.2    Qiu, Y.3
  • 42
    • 18544404101 scopus 로고    scopus 로고
    • Control of endodermal endocrine development by Hes-1
    • Jensen J, Pedersen EE, Galante P, et al. Control of endodermal endocrine development by Hes-1. Nat Genet 2000; 24: 36-44.
    • (2000) Nat. Genet. , vol.24 , pp. 36-44
    • Jensen, J.1    Pedersen, E.E.2    Galante, P.3
  • 43
    • 0034652287 scopus 로고    scopus 로고
    • Neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas
    • Gradwohl G, Dierich A, LeMeur M, Guillemot F. neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc Natl Acad Sci USA 2000; 97: 1607-1611.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 1607-1611
    • Gradwohl, G.1    Dierich, A.2    LeMeur, M.3    Guillemot, F.4
  • 44
    • 0034798317 scopus 로고    scopus 로고
    • Requirement for Pbx1 in skeletal patterning and programming chondrocyte proliferation and differentiation
    • Selleri L, Depew MJ, Jacobs Y, et al. Requirement for Pbx1 in skeletal patterning and programming chondrocyte proliferation and differentiation. Development 2001; 128: 3543-3557.
    • (2001) Development , vol.128 , pp. 3543-3557
    • Selleri, L.1    Depew, M.J.2    Jacobs, Y.3
  • 45
    • 0036544854 scopus 로고    scopus 로고
    • Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice promotes diabetes mellitus
    • Kim SK, Selleri L, Lee JS, et al. Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice promotes diabetes mellitus. Nat Genet 2002; 30: 430-435.
    • (2002) Nat. Genet. , vol.30 , pp. 430-435
    • Kim, S.K.1    Selleri, L.2    Lee, J.S.3
  • 46
    • 0029737816 scopus 로고    scopus 로고
    • The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein
    • Krapp A, Knofler M, Frutiger F, Hughes GJ, Hagenbuchle O, Wellauer PK. The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein. EMBO J 1996; 15: 4317-4329.
    • (1996) EMBO J. , vol.15 , pp. 4317-4329
    • Krapp, A.1    Knofler, M.2    Frutiger, F.3    Hughes, G.J.4    Hagenbuchle, O.5    Wellauer, P.K.6
  • 47
    • 0033869726 scopus 로고    scopus 로고
    • Activin receptor patterning of foregut organogenesis
    • Kim SK, Hebrok M, Li E, et al. Activin receptor patterning of foregut organogenesis. Genes Dev 2000; 14: 1866-1871.
    • (2000) Genes Dev. , vol.14 , pp. 1866-1871
    • Kim, S.K.1    Hebrok, M.2    Li, E.3
  • 48
    • 0037013298 scopus 로고    scopus 로고
    • Brn-4 transcription factor expression targeted to the early developing mouse pancreas induces ectopic glucagon gene expression in insulin-producing beta cells
    • Hussain MA, Miller CP, Habener JF. Brn-4 transcription factor expression targeted to the early developing mouse pancreas induces ectopic glucagon gene expression in insulin-producing beta cells. J Biol Chem 2002; 277: 16 028-16 032.
    • (2002) J. Biol. Chem. , vol.277 , pp. 16028-16032
    • Hussain, M.A.1    Miller, C.P.2    Habener, J.F.3
  • 49
    • 0033825383 scopus 로고    scopus 로고
    • Expression of neurogenin3 reveals an islet cell precursor population in the pancreas
    • Schwitzgebel VM, Scheel DW, Conners JR, et al. Expression of neurogenin3 reveals an islet cell precursor population in the pancreas. Development 2000; 127: 3533-3542.
    • (2000) Development , vol.127 , pp. 3533-3542
    • Schwitzgebel, V.M.1    Scheel, D.W.2    Conners, J.R.3
  • 50
    • 0036340074 scopus 로고    scopus 로고
    • Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors
    • Gu G, Dubauskaite J, Melton DA. Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development 2002; 129: 2447-2457.
    • (2002) Development , vol.129 , pp. 2447-2457
    • Gu, G.1    Dubauskaite, J.2    Melton, D.A.3
  • 51
    • 0036222095 scopus 로고    scopus 로고
    • Pancreatic lineage analysis using a retroviral vector in embryonic mice demonstrates a common progenitor for endocrine and exocrine cells
    • Fishman MP, Melton DA. Pancreatic lineage analysis using a retroviral vector in embryonic mice demonstrates a common progenitor for endocrine and exocrine cells. Int J Dev Biol 2002; 46: 201-207.
    • (2002) Int. J. Dev. Biol. , vol.46 , pp. 201-207
    • Fishman, M.P.1    Melton, D.A.2
  • 52
    • 0029166144 scopus 로고
    • In vivo cell transformation: Neogenesis of beta cells from pancreatic ductal cells
    • Rosenberg L. In vivo cell transformation: neogenesis of beta cells from pancreatic ductal cells. Cell Transplant 1995; 4: 371-383.
    • (1995) Cell Transplant. , vol.4 , pp. 371-383
    • Rosenberg, L.1
  • 53
    • 0032533453 scopus 로고    scopus 로고
    • Induction of islet cell neogenesis in the adult pancreas: The partial duct obstruction model
    • Rosenberg L. Induction of islet cell neogenesis in the adult pancreas: the partial duct obstruction model. Microsc Res Tech 1998; 43: 337-346.
    • (1998) Microsc. Res. Tech. , vol.43 , pp. 337-346
    • Rosenberg, L.1
  • 54
    • 0024458020 scopus 로고
    • Pancreatic beta cell proliferation in rabbits demonstrated by bromodeoxyuridine labeling
    • Davidson PM, Campbell IL, Oxbrow L, Hutson JM, Harrison LC. Pancreatic beta cell proliferation in rabbits demonstrated by bromodeoxyuridine labeling. Pancreas 1989; 4: 594-600.
    • (1989) Pancreas , vol.4 , pp. 594-600
    • Davidson, P.M.1    Campbell, I.L.2    Oxbrow, L.3    Hutson, J.M.4    Harrison, L.C.5
  • 55
    • 0030747894 scopus 로고    scopus 로고
    • Demonstration of two different processes of beta-cell regeneration in a new diabetic mouse model induced by selective perfusion of alloxan
    • Waguri M, Yamamoto K, Miyagawa JI, et al. Demonstration of two different processes of beta-cell regeneration in a new diabetic mouse model induced by selective perfusion of alloxan. Diabetes 1997; 46: 1281-1290.
    • (1997) Diabetes , vol.46 , pp. 1281-1290
    • Waguri, M.1    Yamamoto, K.2    Miyagawa, J.I.3
  • 56
    • 0017179001 scopus 로고
    • Streptozotocin-induced pancreatic insulitis: New model of diabetes mellitus
    • Like AA, Rossini AA. Streptozotocin-induced pancreatic insulitis: new model of diabetes mellitus. Science 1976; 193: 415-417.
    • (1976) Science , vol.193 , pp. 415-417
    • Like, A.A.1    Rossini, A.A.2
  • 57
    • 0022826388 scopus 로고
    • Time course and cellular source of pancreatic regeneration following acute pancreatitis in the rat
    • Elsasser HP, Adler G, Kern HF. Time course and cellular source of pancreatic regeneration following acute pancreatitis in the rat. Pancreas 1986; 1: 421-429.
    • (1986) Pancreas , vol.1 , pp. 421-429
    • Elsasser, H.P.1    Adler, G.2    Kern, H.F.3
  • 58
    • 0033932550 scopus 로고    scopus 로고
    • Neogenesis of pancreatic endocrine cells in copper-deprived rat models
    • [In Process Citation]
    • Al-Abdullah IH, Ayala T, Panigrahi D, Kumar RM, Kumar MS. Neogenesis of pancreatic endocrine cells in copper-deprived rat models [In Process Citation]. Pancreas 2000; 21: 63-68.
    • (2000) Pancreas , vol.21 , pp. 63-68
    • Al-Abdullah, I.H.1    Ayala, T.2    Panigrahi, D.3    Kumar, R.M.4    Kumar, M.S.5
  • 59
    • 0029927506 scopus 로고    scopus 로고
    • The non-human primate endocrine pancreas: Development, regeneration potential and metaplasia
    • Wolfe-Coote S, Louw J, Woodroof C, Du Toit DF. The non-human primate endocrine pancreas: development, regeneration potential and metaplasia. Cell Biol Int 1996; 20: 95-101.
    • (1996) Cell Biol. Int. , vol.20 , pp. 95-101
    • Wolfe-Coote, S.1    Louw, J.2    Woodroof, C.3    Du Toit, D.F.4
  • 60
    • 0030912531 scopus 로고    scopus 로고
    • Cloning and sequencing of the pancreatic islet neogenesis associated protein (INGAP) gene and its expression in islet neogenesis in hamsters
    • Rafaeloff R, Pittenger GL, Barlow SW, et al. Cloning and sequencing of the pancreatic islet neogenesis associated protein (INGAP) gene and its expression in islet neogenesis in hamsters. J Clin Invest 1997; 99: 2100-2109.
    • (1997) J. Clin. Invest. , vol.99 , pp. 2100-2109
    • Rafaeloff, R.1    Pittenger, G.L.2    Barlow, S.W.3
  • 61
    • 0027449197 scopus 로고
    • A second pathway for regeneration of adult exocrine and endocrine pancreas. A possible recapitulation of embryonic development
    • Bonner-Weir S, Baxter LA, Schuppin GT, Smith FE. A second pathway for regeneration of adult exocrine and endocrine pancreas. A possible recapitulation of embryonic development. Diabetes 1993; 42: 1715-1720.
    • (1993) Diabetes , vol.42 , pp. 1715-1720
    • Bonner-Weir, S.1    Baxter, L.A.2    Schuppin, G.T.3    Smith, F.E.4
  • 62
    • 0033009460 scopus 로고    scopus 로고
    • The homeodomain protein IDX-1 increases after an early burst of proliferation during pancreatic regeneration
    • Sharma A, Zangen DH, Reitz P, et al. The homeodomain protein IDX-1 increases after an early burst of proliferation during pancreatic regeneration. Diabetes 1999; 48: 507-513.
    • (1999) Diabetes , vol.48 , pp. 507-513
    • Sharma, A.1    Zangen, D.H.2    Reitz, P.3
  • 63
    • 0034687559 scopus 로고    scopus 로고
    • Diabetes and tumor formation in transgenic mice expressing reg I
    • Yamaoka T, Yoshino K, Yamada T, et al. Diabetes and tumor formation in transgenic mice expressing reg I. Biochem Biophys Res Commun 2000; 278: 368-376.
    • (2000) Biochem. Biophys. Res. Commun. , vol.278 , pp. 368-376
    • Yamaoka, T.1    Yoshino, K.2    Yamada, T.3
  • 64
    • 0033385631 scopus 로고    scopus 로고
    • PDX-1 and Msx-2 expression in the regenerating and developing pancreas
    • Kritzik MR, Jones E, Chen Z, et al. PDX-1 and Msx-2 expression in the regenerating and developing pancreas. J Endocrinol 1999; 163: 523-530.
    • (1999) J. Endocrinol. , vol.163 , pp. 523-530
    • Kritzik, M.R.1    Jones, E.2    Chen, Z.3
  • 65
    • 0030782731 scopus 로고    scopus 로고
    • Endocrine/exocrine intermediate cells in streptozotocin-treated Ins-IFN- gamma transgenic mice
    • Gu D, Arnush M, Sarvetnick N. Endocrine/exocrine intermediate cells in streptozotocin-treated Ins-IFN- gamma transgenic mice. Pancreas 1997; 15: 246-250.
    • (1997) Pancreas , vol.15 , pp. 246-250
    • Gu, D.1    Arnush, M.2    Sarvetnick, N.3
  • 66
    • 0025297086 scopus 로고
    • Overexpression of TGF alpha in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast
    • Sandgren EP, Luetteke NC, Palmiter RD, Brinster RL, Lee DC. Overexpression of TGF alpha in transgenic mice: induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast. Cell 1990; 61: 1121-1135.
    • (1990) Cell , vol.61 , pp. 1121-1135
    • Sandgren, E.P.1    Luetteke, N.C.2    Palmiter, R.D.3    Brinster, R.L.4    Lee, D.C.5
  • 67
    • 0030999982 scopus 로고    scopus 로고
    • Alpha-Cell neogenesis in an animal model of IDDM
    • O'Reilly LA, Gu D, Sarvetnick N, et al. Alpha-Cell neogenesis in an animal model of IDDM. Diabetes 1997; 46: 599-606.
    • (1997) Diabetes , vol.46 , pp. 599-606
    • O'Reilly, L.A.1    Gu, D.2    Sarvetnick, N.3
  • 68
    • 0028243350 scopus 로고
    • Transitional cells in the regenerating pancreas
    • Gu D, Lee MS, Krahl T, Sarvetnick N. Transitional cells in the regenerating pancreas. Development 1994; 120: 1873-1881.
    • (1994) Development , vol.120 , pp. 1873-1881
    • Gu, D.1    Lee, M.S.2    Krahl, T.3    Sarvetnick, N.4
  • 69
    • 0027276885 scopus 로고
    • Epithelial cell proliferation and islet neogenesis in IFN-g transgenic mice
    • Gu D, Sarvetnick N. Epithelial cell proliferation and islet neogenesis in IFN-g transgenic mice. Development 1993; 118: 33-46.
    • (1993) Development , vol.118 , pp. 33-46
    • Gu, D.1    Sarvetnick, N.2
  • 70
    • 0028793314 scopus 로고
    • Duct- to islet-cell differentiation and islet growth in the pancreas of duct-ligated adult rats
    • Wang RN, Kloppel G, Bouwens L. Duct- to islet-cell differentiation and islet growth in the pancreas of duct-ligated adult rats. Diabetologia 1995; 38: 1405-1411.
    • (1995) Diabetologia , vol.38 , pp. 1405-1411
    • Wang, R.N.1    Kloppel, G.2    Bouwens, L.3
  • 71
    • 0032835636 scopus 로고    scopus 로고
    • Massive acinar cell apoptosis with secondary necrosis, origin of ducts in atrophic lobules and failure to regenerate in cyanohydroxybutene pancreatopathy in rats
    • Kelly L, Reid L, Walker NI. Massive acinar cell apoptosis with secondary necrosis, origin of ducts in atrophic lobules and failure to regenerate in cyanohydroxybutene pancreatopathy in rats. Int J Exp Pathol 1999; 80: 217-226.
    • (1999) Int. J. Exp. Pathol. , vol.80 , pp. 217-226
    • Kelly, L.1    Reid, L.2    Walker, N.I.3
  • 72
    • 0030750624 scopus 로고    scopus 로고
    • Morphology of the exocrine pancreas related to pancreatitis
    • Bockman DE. Morphology of the exocrine pancreas related to pancreatitis. Microsc Res Tech 1997; 37: 509-519.
    • (1997) Microsc. Res. Tech. , vol.37 , pp. 509-519
    • Bockman, D.E.1
  • 73
    • 0033911990 scopus 로고    scopus 로고
    • Modulation of rat pancreatic acinoductal transdifferentiation and expression of PDX-1 in vitro
    • Rooman I, Heremans Y, Heimberg H, Bouwens L. Modulation of rat pancreatic acinoductal transdifferentiation and expression of PDX-1 in vitro. Diabetologia 2000; 43: 907-914.
    • (2000) Diabetologia , vol.43 , pp. 907-914
    • Rooman, I.1    Heremans, Y.2    Heimberg, H.3    Bouwens, L.4
  • 74
    • 0029731366 scopus 로고    scopus 로고
    • Redifferentiation and apoptosis of pancreatic cells during acute pancreatitis
    • Iovanna JL. Redifferentiation and apoptosis of pancreatic cells during acute pancreatitis. Int J Pancreatol 1996; 20: 77-84.
    • (1996) Int. J. Pancreatol. , vol.20 , pp. 77-84
    • Iovanna, J.L.1
  • 75
    • 0026608889 scopus 로고
    • Rapid acinar to ductal transdifferentiation in cultured human exocrine pancreas
    • Hall PA, Lemoine NR. Rapid acinar to ductal transdifferentiation in cultured human exocrine pancreas. J Pathol 1992; 166: 97-103.
    • (1992) J. Pathol. , vol.166 , pp. 97-103
    • Hall, P.A.1    Lemoine, N.R.2
  • 76
    • 0026483736 scopus 로고
    • Cytological changes in the pancreas of transgenic mice overexpressing transforming growth factor alpha
    • Bockman DE, Merlino G. Cytological changes in the pancreas of transgenic mice overexpressing transforming growth factor alpha. Gastroenterology 1992; 103: 1883-1892.
    • (1992) Gastroenterology , vol.103 , pp. 1883-1892
    • Bockman, D.E.1    Merlino, G.2
  • 77
    • 0033672199 scopus 로고    scopus 로고
    • Molecular basis of transdifferentiation of pancreas to liver
    • Shen CN, Slack JM, Tosh D. Molecular basis of transdifferentiation of pancreas to liver. Nat Cell Biol 2000; 2: 879-887.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 879-887
    • Shen, C.N.1    Slack, J.M.2    Tosh, D.3
  • 78
    • 0024509369 scopus 로고
    • Histochemical and ultrastructural characteristics of tubular complexes in human acute pancreatitis
    • Willemer S, Adler G. Histochemical and ultrastructural characteristics of tubular complexes in human acute pancreatitis. Dig Dis Sci 1989; 34: 46-55.
    • (1989) Dig. Dis. Sci. , vol.34 , pp. 46-55
    • Willemer, S.1    Adler, G.2
  • 79
    • 0032835634 scopus 로고    scopus 로고
    • Acinar cell apoptosis and the origin of tubular complexes in caerulein-induced pancreatitis
    • Reid LE, Walker NI. Acinar cell apoptosis and the origin of tubular complexes in caerulein-induced pancreatitis. Int J Exp Pathol 1999; 80: 205-215.
    • (1999) Int. J. Exp. Pathol. , vol.80 , pp. 205-215
    • Reid, L.E.1    Walker, N.I.2
  • 80
    • 0036266409 scopus 로고    scopus 로고
    • Matrix metalloproteinase-7 is expressed by pancreatic cancer precursors and regulates acinar-to-ductal metaplasia in exocrine pancreas
    • Crawford HC, Scoggins CR, Washington MK, Matrisian LM, Leach SD. Matrix metalloproteinase-7 is expressed by pancreatic cancer precursors and regulates acinar-to-ductal metaplasia in exocrine pancreas. J Clin Invest 2002; 109: 1437-1444.
    • (2002) J. Clin. Invest. , vol.109 , pp. 1437-1444
    • Crawford, H.C.1    Scoggins, C.R.2    Washington, M.K.3    Matrisian, L.M.4    Leach, S.D.5
  • 81
    • 0034042959 scopus 로고    scopus 로고
    • Islet growth and development in the adult
    • Bonner-Weir S. Islet growth and development in the adult. J Mol Endocrinol 2000; 24: 297-302.
    • (2000) J. Mol. Endocrinol. , vol.24 , pp. 297-302
    • Bonner-Weir, S.1
  • 82
    • 0028987251 scopus 로고
    • Dynamics of beta-cell mass in the growing rat pancreas. Estimation with a simple mathematical model
    • Finegood DT, Scaglia L, Bonner-Weir S. Dynamics of beta-cell mass in the growing rat pancreas. Estimation with a simple mathematical model. Diabetes 1995; 44: 249-256.
    • (1995) Diabetes , vol.44 , pp. 249-256
    • Finegood, D.T.1    Scaglia, L.2    Bonner-Weir, S.3
  • 83
    • 0033513455 scopus 로고    scopus 로고
    • Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats
    • Xu G, Stoffers DA, Habener JF, Bonner-Weir S. Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats. Diabetes 1999; 48: 2270-2276.
    • (1999) Diabetes , vol.48 , pp. 2270-2276
    • Xu, G.1    Stoffers, D.A.2    Habener, J.F.3    Bonner-Weir, S.4
  • 84
    • 0024508097 scopus 로고
    • Compensatory growth of pancreatic beta-cells in adult rats after short-term glucose infusion
    • Bonner-Weir S, Deery D, Leahy JL, Weir GC. Compensatory growth of pancreatic beta-cells in adult rats after short-term glucose infusion. Diabetes 1989; 38: 49-53.
    • (1989) Diabetes , vol.38 , pp. 49-53
    • Bonner-Weir, S.1    Deery, D.2    Leahy, J.L.3    Weir, G.C.4
  • 85
    • 0034457490 scopus 로고    scopus 로고
    • Perspective: Postnatal pancreatic beta cell growth
    • Bonner-Weir S. Perspective: postnatal pancreatic beta cell growth. Endocrinology 2000; 141: 1926-1929.
    • (2000) Endocrinology , vol.141 , pp. 1926-1929
    • Bonner-Weir, S.1
  • 86
    • 0023936007 scopus 로고
    • Morphological evidence for pancreatic polarity of beta-cell within islets of Langerhans
    • Bonner-Weir S. Morphological evidence for pancreatic polarity of beta-cell within islets of Langerhans. Diabetes 1988; 37: 616-621.
    • (1988) Diabetes , vol.37 , pp. 616-621
    • Bonner-Weir, S.1
  • 87
    • 0032932851 scopus 로고    scopus 로고
    • Sustained proliferation of PDX-1+ cells derived from human islets
    • Beattie GM, Itkin-Ansari P, Cirulli V, et al. Sustained proliferation of PDX-1+ cells derived from human islets. Diabetes 1999; 48: 1013-1019.
    • (1999) Diabetes , vol.48 , pp. 1013-1019
    • Beattie, G.M.1    Itkin-Ansari, P.2    Cirulli, V.3
  • 88
    • 0029820477 scopus 로고    scopus 로고
    • Transdifferentiation of human islets to pancreatic ductal cells in collagen matrix culture
    • Yuan S, Rosenberg L, Paraskevas S, Agapitos D, Duguid WP. Transdifferentiation of human islets to pancreatic ductal cells in collagen matrix culture. Differentiation 1996; 61: 67-75.
    • (1996) Differentiation , vol.61 , pp. 67-75
    • Yuan, S.1    Rosenberg, L.2    Paraskevas, S.3    Agapitos, D.4    Duguid, W.P.5
  • 89
    • 0034748027 scopus 로고    scopus 로고
    • Regeneration of pancreatic beta cells from intra-islet precursor cells in an experimental model of diabetes
    • Guz Y, Nasir I, Teitelman G. Regeneration of pancreatic beta cells from intra-islet precursor cells in an experimental model of diabetes. Endocrinology 2001; 142: 4956-4968.
    • (2001) Endocrinology , vol.142 , pp. 4956-4968
    • Guz, Y.1    Nasir, I.2    Teitelman, G.3
  • 90
    • 0033045376 scopus 로고    scopus 로고
    • Prior streptozotocin treatment does not inhibit pancreas regeneration after 90% pancreatectomy in rats
    • Finegood DT, Weir GC, Bonner-Weir S. Prior streptozotocin treatment does not inhibit pancreas regeneration after 90% pancreatectomy in rats. Am J Physiol 1999; 276: E822-E827.
    • (1999) Am. J. Physiol. , vol.276
    • Finegood, D.T.1    Weir, G.C.2    Bonner-Weir, S.3
  • 91
    • 0023874058 scopus 로고
    • A novel gene activated in regenerating islets
    • Terazono K, Yamamoto H, Takasawa S, et al. A novel gene activated in regenerating islets. J Biol Chem 1988; 263: 2111-2114.
    • (1988) J. Biol. Chem. , vol.263 , pp. 2111-2114
    • Terazono, K.1    Yamamoto, H.2    Takasawa, S.3
  • 92
    • 0013674850 scopus 로고
    • Partial purification and characterization of Ilotropin. A pancreatic islet specific growth factor
    • Pittenger G, Rosenberg L, Vinik A. Partial purification and characterization of Ilotropin. A pancreatic islet specific growth factor. J Cell Biol 1991; 115: 270a.
    • (1991) J. Cell Biol. , vol.115
    • Pittenger, G.1    Rosenberg, L.2    Vinik, A.3
  • 93
    • 0030062795 scopus 로고    scopus 로고
    • Islet-cell regeneration in the diabetic hamster pancreas with restoration of normoglycaemia can be induced by a local growth factor(s)
    • Rosenberg L, Vinik AI, Pittenger GL, Rafaeloff R, Duguid WP. Islet-cell regeneration in the diabetic hamster pancreas with restoration of normoglycaemia can be induced by a local growth factor(s). Diabetologia 1996; 39: 256-262.
    • (1996) Diabetologia , vol.39 , pp. 256-262
    • Rosenberg, L.1    Vinik, A.I.2    Pittenger, G.L.3    Rafaeloff, R.4    Duguid, W.P.5
  • 94
    • 0031662468 scopus 로고    scopus 로고
    • Effect of reg protein on rat pancreatic ductal cells
    • Zenilman ME, Chen J, Magnuson TH. Effect of reg protein on rat pancreatic ductal cells. Pancreas 1998; 17: 256-261.
    • (1998) Pancreas , vol.17 , pp. 256-261
    • Zenilman, M.E.1    Chen, J.2    Magnuson, T.H.3
  • 95
    • 0034646675 scopus 로고    scopus 로고
    • Identification of a receptor for reg (regenerating gene) protein, a pancreatic beta-cell regeneration factor
    • Kobayashi S, Akiyama T, Nata K, et al. Identification of a receptor for reg (regenerating gene) protein, a pancreatic beta-cell regeneration factor. J Biol Chem 2000; 275: 10 723-10 726.
    • (2000) J. Biol. Chem. , vol.275 , pp. 10723-10726
    • Kobayashi, S.1    Akiyama, T.2    Nata, K.3
  • 96
    • 0034038355 scopus 로고    scopus 로고
    • Expression of ErbB receptors during pancreatic islet development and regrowth
    • Kritzik MR, Krahl T, Good A, et al. Expression of ErbB receptors during pancreatic islet development and regrowth. J Endocrinol 2000; 165: 67-77.
    • (2000) J. Endocrinol. , vol.165 , pp. 67-77
    • Kritzik, M.R.1    Krahl, T.2    Good, A.3
  • 97
    • 0034854417 scopus 로고    scopus 로고
    • ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini
    • Muthuswamy SK, Li D, Lelievre S, Bissell MJ, Brugge JS. ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini. Nat Cell Biol 2001; 3: 785-792.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 785-792
    • Muthuswamy, S.K.1    Li, D.2    Lelievre, S.3    Bissell, M.J.4    Brugge, J.S.5
  • 98
    • 0033578067 scopus 로고    scopus 로고
    • Conditional expression of the ErbB2 oncogene elicits reversible hyperplasia in stratified epithelia and up-regulation of TGFalpha expression in transgenic mice
    • Xie W, Chow LT, Paterson AJ, Chin E, Kudlow JE. Conditional expression of the ErbB2 oncogene elicits reversible hyperplasia in stratified epithelia and up-regulation of TGFalpha expression in transgenic mice. Oncogene 1999; 18: 3593-3607.
    • (1999) Oncogene , vol.18 , pp. 3593-3607
    • Xie, W.1    Chow, L.T.2    Paterson, A.J.3    Chin, E.4    Kudlow, J.E.5
  • 99
    • 0030960835 scopus 로고    scopus 로고
    • Differentiation of new insulin-producing cells is induced by injury in adult pancreatic islets
    • Fernandes A, King LC, Guz Y, Stein R, Wright CVE, Teitelman G. Differentiation of new insulin-producing cells is induced by injury in adult pancreatic islets. Endocrinology 1997; 138: 1750-1762.
    • (1997) Endocrinology , vol.138 , pp. 1750-1762
    • Fernandes, A.1    King, L.C.2    Guz, Y.3    Stein, R.4    Wright, C.V.E.5    Teitelman, G.6
  • 100
    • 0028136475 scopus 로고
    • Beta cells arise from glucose transporter type 2 (Glut2)-expressing epithelial cells of the developing rat pancreas
    • Pang K, Mukonoweshuro C, Wong GG. Beta cells arise from glucose transporter type 2 (Glut2)-expressing epithelial cells of the developing rat pancreas. Proc Natl Acad Sci U S A 1994; 91: 9559-9563.
    • (1994) Proc. Natl. Acad. Sci. U S A , vol.91 , pp. 9559-9563
    • Pang, K.1    Mukonoweshuro, C.2    Wong, G.G.3
  • 101
    • 24844454591 scopus 로고    scopus 로고
    • Kuzbanian plays an important role in cell fate determination during pancreatic development
    • Kim YJ, Yavari R, Noh H-L, Thomas MK, Philbrick WM, Sherwin RS. Kuzbanian plays an important role in cell fate determination during pancreatic development. Diabetes 2002; 51(Suppl. 2): A378.
    • (2002) Diabetes , vol.51 , Issue.SUPPL. 2
    • Kim, Y.J.1    Yavari, R.2    Noh, H.-L.3    Thomas, M.K.4    Philbrick, W.M.5    Sherwin, R.S.6
  • 102
    • 0032734761 scopus 로고    scopus 로고
    • Expansion of Pdx1-expressing pancreatic epithelium and islet neogenesis in transgenic mice overexpressing transforming growth factor alpha
    • Song SY, Gannon M, Washington MK, et al. Expansion of Pdx1-expressing pancreatic epithelium and islet neogenesis in transgenic mice overexpressing transforming growth factor alpha. Gastroenterology 1999; 117: 1416-1426.
    • (1999) Gastroenterology , vol.117 , pp. 1416-1426
    • Song, S.Y.1    Gannon, M.2    Washington, M.K.3
  • 103
    • 0036307240 scopus 로고    scopus 로고
    • Functional genomics of the endocrine pancreas: The pancreas clone set and PancChip, new resources for diabetes research
    • Scearce LM, Brestelli JE, McWeeney SK, et al. Functional genomics of the endocrine pancreas: the pancreas clone set and PancChip, new resources for diabetes research. Diabetes 2002; 51: 1997-2004.
    • (2002) Diabetes , vol.51 , pp. 1997-2004
    • Scearce, L.M.1    Brestelli, J.E.2    McWeeney, S.K.3
  • 104
    • 0037033798 scopus 로고    scopus 로고
    • Clonal identification and characterization of self-renewing pluripotent stem cells in the developing liver
    • Suzuki A, Zheng YW, Kaneko S, et al. Clonal identification and characterization of self-renewing pluripotent stem cells in the developing liver. J Cell Biol 2002; 156: 173-184.
    • (2002) J. Cell Biol. , vol.156 , pp. 173-184
    • Suzuki, A.1    Zheng, Y.W.2    Kaneko, S.3
  • 105
    • 84956427297 scopus 로고
    • A direct measurement of the radiation sensitivity of normal mouse bone marrow cells
    • Till JE, McCulloch EA. A direct measurement of the radiation sensitivity of normal mouse bone marrow cells. Radiat Res. 1961; 14: 1419-1430.
    • (1961) Radiat. Res. , vol.14 , pp. 1419-1430
    • Till, J.E.1    McCulloch, E.A.2
  • 107
    • 0034614576 scopus 로고    scopus 로고
    • Stem cells: Units of development, units of regeneration, and units in evolution
    • Weissman IL. Stem cells: units of development, units of regeneration, and units in evolution. Cell 2000; 100: 157-168.
    • (2000) Cell , vol.100 , pp. 157-168
    • Weissman, I.L.1
  • 108
    • 0019826665 scopus 로고
    • Establishment in culture of pluripotential cells from mouse embryos
    • Evans MJ, Kaufman MH. Establishment in culture of pluripotential cells from mouse embryos. Nature 1981; 292: 154-156.
    • (1981) Nature , vol.292 , pp. 154-156
    • Evans, M.J.1    Kaufman, M.H.2
  • 109
    • 0028841640 scopus 로고
    • In vitro differentiation of embryonic stem cells
    • Keller GM. In vitro differentiation of embryonic stem cells. Curr Opin Cell Biol 1995; 7: 862-869.
    • (1995) Curr. Opin. Cell Biol. , vol.7 , pp. 862-869
    • Keller, G.M.1
  • 110
    • 0030019992 scopus 로고    scopus 로고
    • In vitro differentiation of murine embryonic stem cells. New approaches to old problems
    • Weiss MJ, Orkin SH. In vitro differentiation of murine embryonic stem cells. New approaches to old problems. J Clin Invest 1996; 97: 591-595.
    • (1996) J. Clin. Invest. , vol.97 , pp. 591-595
    • Weiss, M.J.1    Orkin, S.H.2
  • 111
    • 0025975926 scopus 로고
    • Multiple hematopoietic lineages develop from embryonic stem (ES) cells in culture
    • Wiles MV, Keller G. Multiple hematopoietic lineages develop from embryonic stem (ES) cells in culture. Development 1991; 111: 259-267.
    • (1991) Development , vol.111 , pp. 259-267
    • Wiles, M.V.1    Keller, G.2
  • 112
    • 0023836015 scopus 로고
    • Vasculogenesis and angiogenesis in embryonic-stem-cell-derived embryoid bodies
    • Risau W, Sariola H, Zerwes HG, et al. Vasculogenesis and angiogenesis in embryonic-stem-cell-derived embryoid bodies. Development 1988; 102: 471-478.
    • (1988) Development , vol.102 , pp. 471-478
    • Risau, W.1    Sariola, H.2    Zerwes, H.G.3
  • 113
    • 0032724925 scopus 로고    scopus 로고
    • An in vitro pathway from embryonic stem cells to neurons and glia
    • Gottlieb DI, Huettner JE. An in vitro pathway from embryonic stem cells to neurons and glia. Cells Tissues Organs 1999; 165: 165-172.
    • (1999) Cells Tissues Organs , vol.165 , pp. 165-172
    • Gottlieb, D.I.1    Huettner, J.E.2
  • 114
    • 0021891053 scopus 로고
    • The in vitro development of blastocyst-derived embryonic stem cell lines: Formation of visceral yolk sac, blood islands and myocardium
    • Doetschman TC, Eistetter H, Katz M, Schmidt W, Kemler R. The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium. J Embryol Exp Morphol 1985; 87: 27-45.
    • (1985) J. Embryol. Exp. Morphol. , vol.87 , pp. 27-45
    • Doetschman, T.C.1    Eistetter, H.2    Katz, M.3    Schmidt, W.4    Kemler, R.5
  • 115
    • 0027980468 scopus 로고
    • Muscle cell differentiation of embryonic stem cells reflects myogenesis in vivo: Developmentally regulated expression of myogenic determination genes and functional expression of ionic currents
    • Rohwedel J, Maltsev V, Bober E, Arnold HH, Hescheler J, Wobus AM. Muscle cell differentiation of embryonic stem cells reflects myogenesis in vivo: developmentally regulated expression of myogenic determination genes and functional expression of ionic currents. Dev Biol 1994; 164: 87-101.
    • (1994) Dev. Biol. , vol.164 , pp. 87-101
    • Rohwedel, J.1    Maltsev, V.2    Bober, E.3    Arnold, H.H.4    Hescheler, J.5    Wobus, A.M.6
  • 116
    • 0032745956 scopus 로고    scopus 로고
    • Embryonic stem cell-derived adipogenesis
    • Dani C. Embryonic stem cell-derived adipogenesis. Cells Tissues Organs 1999; 165: 173-180.
    • (1999) Cells Tissues Organs , vol.165 , pp. 173-180
    • Dani, C.1
  • 117
    • 0034633526 scopus 로고    scopus 로고
    • From the cover: Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells
    • Schuldiner M, Yanuka O, Itskovitz-Eldor J, Melton DA, Benvenisty N. From the cover: effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells. Proc Natl Acad Sci U S A 2000; 97: 11 307-11 312.
    • (2000) Proc. Natl. Acad. Sci. U S A , vol.97 , pp. 11307-11312
    • Schuldiner, M.1    Yanuka, O.2    Itskovitz-Eldor, J.3    Melton, D.A.4    Benvenisty, N.5
  • 118
    • 0033979603 scopus 로고    scopus 로고
    • Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice
    • Soria B, Roche E, Berna G, Leon-Quinto T, Reig JA, Martin F. Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice. Diabetes 2000; 49: 157-162.
    • (2000) Diabetes , vol.49 , pp. 157-162
    • Soria, B.1    Roche, E.2    Berna, G.3    Leon-Quinto, T.4    Reig, J.A.5    Martin, F.6
  • 120
    • 0035991639 scopus 로고    scopus 로고
    • Identification of insulin-producing cells derived from embryonic stem cells by zinc-chelating dithizone
    • Shiroi A, Yoshikawa M, Yokota H, et al. Identification of insulin-producing cells derived from embryonic stem cells by zinc-chelating dithizone. Stem Cells 2002; 20: 284-292.
    • (2002) Stem Cells , vol.20 , pp. 284-292
    • Shiroi, A.1    Yoshikawa, M.2    Yokota, H.3
  • 121
    • 0034044317 scopus 로고    scopus 로고
    • Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells
    • Lee SH, Lumelsky N, Studer L, Auerbach JM, McKay RD. Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells. Nat Biotechnol 2000; 18: 675-679.
    • (2000) Nat. Biotechnol. , vol.18 , pp. 675-679
    • Lee, S.H.1    Lumelsky, N.2    Studer, L.3    Auerbach, J.M.4    McKay, R.D.5
  • 122
    • 0035906902 scopus 로고    scopus 로고
    • Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets
    • Lumelsky N, Blondel O, Laeng P, Velasco I, Ravin R, McKay R. Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets. Science 2001; 292: 1389-1394.
    • (2001) Science , vol.292 , pp. 1389-1394
    • Lumelsky, N.1    Blondel, O.2    Laeng, P.3    Velasco, I.4    Ravin, R.5    McKay, R.6
  • 123
    • 0026535505 scopus 로고
    • Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system
    • Reynolds BA, Weiss S. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 1992; 255: 1707-1710.
    • (1992) Science , vol.255 , pp. 1707-1710
    • Reynolds, B.A.1    Weiss, S.2
  • 124
    • 0035182533 scopus 로고    scopus 로고
    • Stem and progenitor cells: Origins, phenotypes, lineage commitments, and transdifferentiations
    • Weissman IL, Anderson DJ, Gage F. Stem and progenitor cells: origins, phenotypes, lineage commitments, and transdifferentiations. Anna Rev Cell Dev Biol 2001; 17: 387-403.
    • (2001) Anna. Rev. Cell Dev. Biol. , vol.17 , pp. 387-403
    • Weissman, I.L.1    Anderson, D.J.2    Gage, F.3
  • 125
    • 0034718599 scopus 로고    scopus 로고
    • Enrichment for murine keratinocyte stem cells based on cell surface phenotype
    • Tani H, Morris RJ, Kaur P. Enrichment for murine keratinocyte stem cells based on cell surface phenotype. Proc Natl Acad Sci U S A 2000; 97: 10 960-10 965.
    • (2000) Proc. Natl. Acad. Sci. U S A , vol.97 , pp. 10960-10965
    • Tani, H.1    Morris, R.J.2    Kaur, P.3
  • 126
    • 0034783386 scopus 로고    scopus 로고
    • Murine epidermal label-retaining cells isolated by flow cytometry do not express the stem cell markers CD34, Sca-1, or Flk-1
    • Albert MR, Foster RA, Vogel JC. Murine epidermal label-retaining cells isolated by flow cytometry do not express the stem cell markers CD34, Sca-1, or Flk-1. J Invest Dermatol 2001; 117: 943-948.
    • (2001) J. Invest. Dermatol. , vol.117 , pp. 943-948
    • Albert, M.R.1    Foster, R.A.2    Vogel, J.C.3
  • 127
    • 0037019337 scopus 로고    scopus 로고
    • Pluripotency of mesenchymal stem cells derived from adult marrow
    • Jiang Y, Jahagirdar BN, Reinhardt RL, et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002; 418: 41-49.
    • (2002) Nature , vol.418 , pp. 41-49
    • Jiang, Y.1    Jahagirdar, B.N.2    Reinhardt, R.L.3
  • 128
    • 0035525779 scopus 로고    scopus 로고
    • Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells
    • Reyes M, Lund T, Lenvik T, Aguiar D, Koodie L, Verfaillie CM. Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells. Blood 2001; 98: 2615-2625.
    • (2001) Blood , vol.98 , pp. 2615-2625
    • Reyes, M.1    Lund, T.2    Lenvik, T.3    Aguiar, D.4    Koodie, L.5    Verfaillie, C.M.6
  • 129
    • 0036007425 scopus 로고    scopus 로고
    • The intestinal epithelial stem cell
    • Marshman E, Booth C, Potten CS. The intestinal epithelial stem cell. BioEssays 2002; 24: 91-98.
    • (2002) BioEssays , vol.24 , pp. 91-98
    • Marshman, E.1    Booth, C.2    Potten, C.S.3
  • 131
    • 0033406436 scopus 로고    scopus 로고
    • Hematopoietic potential of stem cells isolated from murine skeletal muscle
    • Jackson KA, Mi T, Goodell MA. Hematopoietic potential of stem cells isolated from murine skeletal muscle. Proc Natl Acad Sci U S A 1999; 96: 14482-14486.
    • (1999) Proc. Natl. Acad. Sci. U S A , vol.96 , pp. 14482-14486
    • Jackson, K.A.1    Mi, T.2    Goodell, M.A.3
  • 133
    • 0037041427 scopus 로고    scopus 로고
    • Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion
    • Terada N, Hamazaki T, Oka M, et al. Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion. Nature 2002; 416: 542-545.
    • (2002) Nature , vol.416 , pp. 542-545
    • Terada, N.1    Hamazaki, T.2    Oka, M.3
  • 135
    • 0033459561 scopus 로고    scopus 로고
    • The power of stem cells reconsidered?
    • Lemischka I. The power of stem cells reconsidered? Proc Natl Acad Sci U S A 1999; 96: 14 193-14 195.
    • (1999) Proc. Natl. Acad. Sci. U S A , vol.96 , pp. 14193-14195
    • Lemischka, I.1
  • 137
    • 0037183884 scopus 로고    scopus 로고
    • Little evidence for developmental plasticity of adult hematopoietic stem cells
    • Wagers AJ, Sherwood RI, Christensen JL, Weissman IL. Little evidence for developmental plasticity of adult hematopoietic stem cells. Science 2002; 297: 2256-2259.
    • (2002) Science , vol.297 , pp. 2256-2259
    • Wagers, A.J.1    Sherwood, R.I.2    Christensen, J.L.3    Weissman, I.L.4
  • 138
    • 2042538384 scopus 로고    scopus 로고
    • Recruitment of bone-marrow-derived cells by skeletal and cardiac muscle in adult dystrophic mdx mice
    • Bittner RE, Schofer C, Weipoltshammer K, et al. Recruitment of bone-marrow-derived cells by skeletal and cardiac muscle in adult dystrophic mdx mice. Anat Embryol (Berl) 1999; 199: 391-396.
    • (1999) Anat. Embryol. (Berl) , vol.199 , pp. 391-396
    • Bittner, R.E.1    Schofer, C.2    Weipoltshammer, K.3
  • 139
    • 0034988491 scopus 로고    scopus 로고
    • Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells
    • Jackson KA, Majka SM, Wang H, et al. Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells. J Clin Invest 2001; 107: 1395-1402.
    • (2001) J. Clin. Invest. , vol.107 , pp. 1395-1402
    • Jackson, K.A.1    Majka, S.M.2    Wang, H.3
  • 140
    • 0035810240 scopus 로고    scopus 로고
    • Bone marrow cells regenerate infarcted myocardium
    • Orlic D, Kajstura J, Chimenti S, et al. Bone marrow cells regenerate infarcted myocardium. Nature 2001; 410: 701-705.
    • (2001) Nature , vol.410 , pp. 701-705
    • Orlic, D.1    Kajstura, J.2    Chimenti, S.3
  • 141
    • 0032489651 scopus 로고    scopus 로고
    • Muscle regeneration by bone marrow-derived myogenic progenitors
    • Ferrari G, Cusella-De Angelis G, Coletta M, et al. Muscle regeneration by bone marrow-derived myogenic progenitors. Science 1998; 279: 1528-1530.
    • (1998) Science , vol.279 , pp. 1528-1530
    • Ferrari, G.1    Cusella-De Angelis, G.2    Coletta, M.3
  • 142
    • 0033598374 scopus 로고    scopus 로고
    • Dystrophin expression in the mdx mouse restored by stem cell transplantation
    • Gussoni E, Soneoka Y, Strickland CD, et al. Dystrophin expression in the mdx mouse restored by stem cell transplantation. Nature 1999; 401: 390-394.
    • (1999) Nature , vol.401 , pp. 390-394
    • Gussoni, E.1    Soneoka, Y.2    Strickland, C.D.3
  • 143
    • 0034531907 scopus 로고    scopus 로고
    • From marrow to brain: Expression of neuronal phenotypes in adult mice
    • Brazelton TR, Rossi FM, Keshet GI, Blau HM. From marrow to brain: expression of neuronal phenotypes in adult mice. Science 2000; 290: 1775-1779.
    • (2000) Science , vol.290 , pp. 1775-1779
    • Brazelton, T.R.1    Rossi, F.M.2    Keshet, G.I.3    Blau, H.M.4
  • 144
    • 0032874061 scopus 로고    scopus 로고
    • Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains
    • Kopen GC, Prockop DJ, Phinney DG. Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains. Proc Natl Acad Sci U S A 1999; 96: 10 711-10 716.
    • (1999) Proc. Natl. Acad. Sci. U S A , vol.96 , pp. 10711-10716
    • Kopen, G.C.1    Prockop, D.J.2    Phinney, D.G.3
  • 145
    • 0034532106 scopus 로고    scopus 로고
    • Turning blood into brain: Cells bearing neuronal antigens generated in vivo from bone marrow
    • Mezey E, Chandross KJ, Harta G, Maki RA, McKercher SR. Turning blood into brain: cells bearing neuronal antigens generated in vivo from bone marrow. Science 2000; 290: 1779-1782.
    • (2000) Science , vol.290 , pp. 1779-1782
    • Mezey, E.1    Chandross, K.J.2    Harta, G.3    Maki, R.A.4    McKercher, S.R.5
  • 147
    • 0033989026 scopus 로고    scopus 로고
    • Origins of circulating endothelial cells and endothelial outgrowth from blood
    • Lin Y, Weisdorf DJ, Solovey A, Hebbel RP. Origins of circulating endothelial cells and endothelial outgrowth from blood. J Clin Invest 2000; 105: 71-77.
    • (2000) J. Clin. Invest. , vol.105 , pp. 71-77
    • Lin, Y.1    Weisdorf, D.J.2    Solovey, A.3    Hebbel, R.P.4
  • 148
    • 0033529618 scopus 로고    scopus 로고
    • Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization
    • Asahara T, Masuda H, Takahashi T, et al. Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization. Circ Res 1999; 85: 221-228.
    • (1999) Circ. Res. , vol.85 , pp. 221-228
    • Asahara, T.1    Masuda, H.2    Takahashi, T.3
  • 149
    • 0033694301 scopus 로고    scopus 로고
    • Purified hematopoietic stem cells can differentiate into hepatocytes in vivo
    • Lagasse E, Connors H, Al-Dhalimy M, et al. Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nat Med 2000; 6: 1229-1234.
    • (2000) Nat. Med. , vol.6 , pp. 1229-1234
    • Lagasse, E.1    Connors, H.2    Al-Dhalimy, M.3
  • 150
    • 0033553591 scopus 로고    scopus 로고
    • Bone marrow as a potential source of hepatic oval cells
    • Petersen BE, Bowen WC, Patrene KD, et al. Bone marrow as a potential source of hepatic oval cells. Science 1999; 284: 1168-1170.
    • (1999) Science , vol.284 , pp. 1168-1170
    • Petersen, B.E.1    Bowen, W.C.2    Patrene, K.D.3
  • 151
    • 0033958372 scopus 로고    scopus 로고
    • Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation
    • Theise ND, Badve S, Saxena R, et al. Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation. Hepatology 2000; 31: 235-240.
    • (2000) Hepatology , vol.31 , pp. 235-240
    • Theise, N.D.1    Badve, S.2    Saxena, R.3
  • 153
    • 0035805055 scopus 로고    scopus 로고
    • Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell
    • Krause DS, Theise ND, Collector MI, et al. Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell. Cell 2001; 105: 369-377.
    • (2001) Cell , vol.105 , pp. 369-377
    • Krause, D.S.1    Theise, N.D.2    Collector, M.I.3
  • 154
    • 0036129310 scopus 로고    scopus 로고
    • Hematopoietic competence is a rare property of neural stem cells that may depend on genetic and epigenetic alterations
    • Morshead CM, Benveniste P, Iscove NN, van der Kooy D. Hematopoietic competence is a rare property of neural stem cells that may depend on genetic and epigenetic alterations. Nat Med 2002; 8: 268-273.
    • (2002) Nat. Med. , vol.8 , pp. 268-273
    • Morshead, C.M.1    Benveniste, P.2    Iscove, N.N.3    van der Kooy, D.4
  • 155
    • 0033593654 scopus 로고    scopus 로고
    • Turning brain into blood: A hematopoietic fate adopted by adult neural stem cells in vivo
    • Bjornson CR, Rietze RL, Reynolds BA, Magli MC, Vescovi AL. Turning brain into blood: a hematopoietic fate adopted by adult neural stem cells in vivo. Science 1999; 283: 534-537.
    • (1999) Science , vol.283 , pp. 534-537
    • Bjornson, C.R.1    Rietze, R.L.2    Reynolds, B.A.3    Magli, M.C.4    Vescovi, A.L.5
  • 156
    • 0033804048 scopus 로고    scopus 로고
    • Skeletal myogenic potential of human and mouse neural stem cells
    • Galli R, Borello U, Gritti A, et al. Skeletal myogenic potential of human and mouse neural stem cells. Nat Neurosci 2000; 3: 986-991.
    • (2000) Nat. Neurosci. , vol.3 , pp. 986-991
    • Galli, R.1    Borello, U.2    Gritti, A.3
  • 157
    • 0034595855 scopus 로고    scopus 로고
    • Generalized potential of adult neural stem cells
    • Clarke DL, Johansson CB, Wilbertz J, et al. Generalized potential of adult neural stem cells. Science 2000; 288: 1660-1663.
    • (2000) Science , vol.288 , pp. 1660-1663
    • Clarke, D.L.1    Johansson, C.B.2    Wilbertz, J.3
  • 158
    • 0034142198 scopus 로고    scopus 로고
    • Role of muscle-derived cells in hematopoietic reconstitution of irradiated mice
    • Pang W. Role of muscle-derived cells in hematopoietic reconstitution of irradiated mice. Blood 2000; 95: 1106-1108.
    • (2000) Blood , vol.95 , pp. 1106-1108
    • Pang, W.1
  • 159
    • 0034848122 scopus 로고    scopus 로고
    • Isolation of multipotent adult stem cells from the dermis of mammalian skin
    • Toma JG, Akhavan M, Fernandes KJ, et al. Isolation of multipotent adult stem cells from the dermis of mammalian skin. Nat Cell Biol 2001; 3: 778-784.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 778-784
    • Toma, J.G.1    Akhavan, M.2    Fernandes, K.J.3
  • 160
    • 0035130297 scopus 로고    scopus 로고
    • Beta-cell turnover: Its assessment and implications
    • Bonner-Weir S. beta-cell turnover: its assessment and implications. Diabetes 2001; 50(Suppl. 1): S20-S24.
    • (2001) Diabetes , vol.50 , Issue.SUPPL. 1
    • Bonner-Weir, S.1
  • 161
    • 0034100823 scopus 로고    scopus 로고
    • Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells
    • Ramiya VK, Maraist M, Arfors KE, Schatz DA, Peck AB, Cornelius JG. Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells. Nat Med 2000; 6: 278-282.
    • (2000) Nat. Med. , vol.6 , pp. 278-282
    • Ramiya, V.K.1    Maraist, M.2    Arfors, K.E.3    Schatz, D.A.4    Peck, A.B.5    Cornelius, J.G.6
  • 162
    • 0034608816 scopus 로고    scopus 로고
    • In vitro cultivation of human islets from expanded ductal tissue
    • Bonner-Weir S, Taneja M, Weir GC, et al. In vitro cultivation of human islets from expanded ductal tissue. Proc Natl Acad Sci U S A 2000; 97: 7999-8004.
    • (2000) Proc. Natl. Acad. Sci. U S A , vol.97 , pp. 7999-8004
    • Bonner-Weir, S.1    Taneja, M.2    Weir, G.C.3
  • 163
    • 0035119871 scopus 로고    scopus 로고
    • Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes
    • Zulewski H, Abraham EJ, Gerlach MJ, et al. Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes. Diabetes 2001; 50: 521-533.
    • (2001) Diabetes , vol.50 , pp. 521-533
    • Zulewski, H.1    Abraham, E.J.2    Gerlach, M.J.3
  • 164
    • 0036297914 scopus 로고    scopus 로고
    • Nestin-positive progenitor cells derived from adult human pancreatic islets of Langerhans contain side population (SP) cells defined by expression of the ABCG2 (BCRP1) ATP-binding cassette transporter
    • Lechner A, Leech CA, Abraham EJ, Nolan AL, Habener JF. Nestin-positive progenitor cells derived from adult human pancreatic islets of Langerhans contain side population (SP) cells defined by expression of the ABCG2 (BCRP1) ATP-binding cassette transporter. Biochem Biophys Res Commun 2002; 293: 670-674.
    • (2002) Biochem. Biophys. Res. Commun. , vol.293 , pp. 670-674
    • Lechner, A.1    Leech, C.A.2    Abraham, E.J.3    Nolan, A.L.4    Habener, J.F.5
  • 165
    • 0035177262 scopus 로고    scopus 로고
    • Identification and isolation of human prostate epithelial stem cells based on alpha (2) beta (1)-integrin expression
    • Collins AT, Habib FK, Maitland NJ, Neal DE. Identification and isolation of human prostate epithelial stem cells based on alpha (2) beta (1)-integrin expression. J Cell Sci 2001; 114: 3865-3872.
    • (2001) J. Cell Sci. , vol.114 , pp. 3865-3872
    • Collins, A.T.1    Habib, F.K.2    Maitland, N.J.3    Neal, D.E.4
  • 166
    • 0037166930 scopus 로고    scopus 로고
    • Proximal location of mouse prostate epithelial stem cells: A model of prostatic homeostasis
    • Tsujimura A, Koikawa Y, Salm S, et al. Proximal location of mouse prostate epithelial stem cells: a model of prostatic homeostasis. J Cell Biol 2002; 157: 1257-1265.
    • (2002) J. Cell Biol. , vol.157 , pp. 1257-1265
    • Tsujimura, A.1    Koikawa, Y.2    Salm, S.3
  • 167
    • 0036570144 scopus 로고    scopus 로고
    • Sea-1 (pos) cells in the mouse mammary gland represent an enriched progenitor cell population
    • Welm BE, Tepera SB, Venezia T, Graubert TA, Rosen JM, Goodell MA. Sea-1 (pos) cells in the mouse mammary gland represent an enriched progenitor cell population. Dev Biol 2002; 245: 42-56.
    • (2002) Dev. Biol. , vol.245 , pp. 42-56
    • Welm, B.E.1    Tepera, S.B.2    Venezia, T.3    Graubert, T.A.4    Rosen, J.M.5    Goodell, M.A.6
  • 168
    • 0037087738 scopus 로고    scopus 로고
    • Isolation, immortalization, and characterization of a human breast epithelial cell line with stem cell properties
    • Gudjonsson T, Villadsen R, Nielsen HL, Ronnov-Jessen L, Bissell MJ, Petersen OW. Isolation, immortalization, and characterization of a human breast epithelial cell line with stem cell properties. Genes Dev 2002; 16: 693-706.
    • (2002) Genes Dev. , vol.16 , pp. 693-706
    • Gudjonsson, T.1    Villadsen, R.2    Nielsen, H.L.3    Ronnov-Jessen, L.4    Bissell, M.J.5    Petersen, O.W.6
  • 169
    • 0033545723 scopus 로고    scopus 로고
    • Betal- and alpha6-integrin are surface markers on mouse spermatogonial stem cells
    • Shinohara T, Avarbock MR, Brinster RL. betal- and alpha6-integrin are surface markers on mouse spermatogonial stem cells. Proc Natl Acad Sci U S A 1999; 96: 5504-5509.
    • (1999) Proc. Natl. Acad. Sci. U S A , vol.96 , pp. 5504-5509
    • Shinohara, T.1    Avarbock, M.R.2    Brinster, R.L.3
  • 170
    • 0035887289 scopus 로고    scopus 로고
    • Involvement of laminin binding integrins and laminin-5 in branching morphogenesis of the ureteric bud during kidney development
    • Zent R, Bush KT, Pohl ML, et al. Involvement of laminin binding integrins and laminin-5 in branching morphogenesis of the ureteric bud during kidney development. Dev Biol 2001; 238: 289-302.
    • (2001) Dev. Biol. , vol.238 , pp. 289-302
    • Zent, R.1    Bush, K.T.2    Pohl, M.L.3
  • 171
    • 0034745181 scopus 로고    scopus 로고
    • Loss of alpha3beta1 integrin function results in an altered differentiation program in the mouse submandibular gland
    • Menko AS, Kreidberg JA, Ryan TT, Van Bockstaele E, Kukuruzinska MA. Loss of alpha3beta1 integrin function results in an altered differentiation program in the mouse submandibular gland. Dev Dyn 2001; 220: 337-349.
    • (2001) Dev. Dyn. , vol.220 , pp. 337-349
    • Menko, A.S.1    Kreidberg, J.A.2    Ryan, T.T.3    Van Bockstaele, E.4    Kukuruzinska, M.A.5
  • 172
    • 0036499791 scopus 로고    scopus 로고
    • Differential expression of alpha 3 and alpha 6 integrins in the developing mouse inner ear
    • Davies D, Holley MC. Differential expression of alpha 3 and alpha 6 integrins in the developing mouse inner ear. J Comp Neurol 2002; 445: 122-132.
    • (2002) J. Comp. Neurol. , vol.445 , pp. 122-132
    • Davies, D.1    Holley, M.C.2
  • 173
    • 0034683747 scopus 로고    scopus 로고
    • Expression and function of alpha(v)beta(3) and alpha(v)beta(5) integrins in the developing pancreas: Roles in the adhesion and migration of putative endocrine progenitor cells
    • Cirulli V, Beattie GM, Klier G, et al. Expression and function of alpha(v)beta(3) and alpha(v)beta(5) integrins in the developing pancreas: roles in the adhesion and migration of putative endocrine progenitor cells. J Cell Biol 2000; 150: 1445-1460.
    • (2000) J. Cell Biol. , vol.150 , pp. 1445-1460
    • Cirulli, V.1    Beattie, G.M.2    Klier, G.3
  • 175
    • 0035260033 scopus 로고    scopus 로고
    • Regulation of laminin 1-induced pancreatic beta-cell differentiation by alpha6 integrin and alpha-dystroglycan
    • Jiang FX, Georges-Labouesse E, Harrison LC. Regulation of laminin 1-induced pancreatic beta-cell differentiation by alpha6 integrin and alpha-dystroglycan. Mol Med 2001; 7: 107-114.
    • (2001) Mol. Med. , vol.7 , pp. 107-114
    • Jiang, F.X.1    Georges-Labouesse, E.2    Harrison, L.C.3
  • 176
    • 0037071546 scopus 로고    scopus 로고
    • Identification of myogenic-endothelial progenitor cells in the interstitial spaces of skeletal muscle
    • Tamaki T, Akatsuka A, Ando K, et al. Identification of myogenic-endothelial progenitor cells in the interstitial spaces of skeletal muscle. J Cell Biol 2002; 157: 571-577.
    • (2002) J. Cell Biol. , vol.157 , pp. 571-577
    • Tamaki, T.1    Akatsuka, A.2    Ando, K.3
  • 177
    • 0036721301 scopus 로고    scopus 로고
    • Up-regulation of the expression of activins in the pancreatic duct by reduction of the beta-cell mass
    • Zhang YQ, Zhang H, Maeshima A, et al. Up-regulation of the expression of activins in the pancreatic duct by reduction of the beta-cell mass. Endocrinology 2002; 143: 3540-3547.
    • (2002) Endocrinology , vol.143 , pp. 3540-3547
    • Zhang, Y.Q.1    Zhang, H.2    Maeshima, A.3
  • 178
    • 0036230386 scopus 로고    scopus 로고
    • Nestin is expressed in mesenchymal and not epithelial cells of the developing mouse pancreas
    • Selander L, Edlund H. Nestin is expressed in mesenchymal and not epithelial cells of the developing mouse pancreas. Mech Dev 2002; 113: 189-192.
    • (2002) Mech. Dev. , vol.113 , pp. 189-192
    • Selander, L.1    Edlund, H.2
  • 179
    • 0036082806 scopus 로고    scopus 로고
    • Nestin expression in pancreatic stellate cells and angiogenic endothelial cells
    • Lardon J, Rooman I, Bouwens L. Nestin expression in pancreatic stellate cells and angiogenic endothelial cells. Histochem Cell Biol 2002; 117: 535-540.
    • (2002) Histochem. Cell Biol. , vol.117 , pp. 535-540
    • Lardon, J.1    Rooman, I.2    Bouwens, L.3
  • 180
    • 0036315648 scopus 로고    scopus 로고
    • Beta-cell differentiation during human development does not rely on nestin-positive precursors: Implications for stem cell-derived replacement therapy
    • Piper K, Ball SG, Turnpenny LW, Brickwood S, Wilson DI, Hanley NA. Beta-cell differentiation during human development does not rely on nestin-positive precursors: implications for stem cell-derived replacement therapy. Diabetologia 2002; 45: 1045-1047.
    • (2002) Diabetologia , vol.45 , pp. 1045-1047
    • Piper, K.1    Ball, S.G.2    Turnpenny, L.W.3    Brickwood, S.4    Wilson, D.I.5    Hanley, N.A.6
  • 181
    • 0018102359 scopus 로고
    • The relationship between the spleen colony-forming cell and the haemopoietic stem cell
    • Schofield R. The relationship between the spleen colony-forming cell and the haemopoietic stem cell. Blood Cells 1978; 4: 7-25.
    • (1978) Blood Cells , vol.4 , pp. 7-25
    • Schofield, R.1
  • 182
    • 0036942123 scopus 로고    scopus 로고
    • Distinct distribution of laminin and its integrin receptors in the pancreas
    • in press
    • Jiang FX, Naselli G, Harrison LC. Distinct distribution of laminin and its integrin receptors in the pancreas. J Histochem Cytochem 2002; in press.
    • (2002) J. Histochem. Cytochem.
    • Jiang, F.X.1    Naselli, G.2    Harrison, L.C.3


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