Activin receptor patterning of foregut organogenesis

Genes and Development

Volumn 14, Issue 15, 2000, Pages 1866-1871

  Kim, Seung K ^a   Hebrok, Matthias ^b,f   Li, En ^c   Oh, S Paul ^d   Schrewe, Heinrich ^e   Harmon, Erin B ^e   Lee, Joon S ^a   Melton, Douglas A ^b  

^a STANFORD UNIVERSITY   (United States)

^b HARVARD UNIVERSITY   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d UNIVERSITY OF FLORIDA   (United States)

^e MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Activin; Diabetes mellitus; Endoderm; Foregut; Hedgehog; Pancreas

Indexed keywords

ACTIVIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; GASTROINTESTINAL TRACT; GENE EXPRESSION; GENE TARGETING; HISTOPATHOLOGY; HYPOINSULINEMIA; HYPOPLASIA; IMPAIRED GLUCOSE TOLERANCE; MOUSE; NONHUMAN; ORGANOGENESIS; PANCREAS ISLET CELL; PRIORITY JOURNAL; PROTEIN FAMILY; SIGNAL TRANSDUCTION;

ACTIVIN RECEPTORS, TYPE II; ANIMALS; BODY PATTERNING; CELL DIFFERENTIATION; DIGESTIVE PHYSIOLOGY; DIGESTIVE SYSTEM; GLUCOSE TOLERANCE TEST; HEDGEHOG PROTEINS; HOMEODOMAIN PROTEINS; HYPERPLASIA; INSULIN; MALE; MICE; MICE, MUTANT STRAINS; NERVE TISSUE PROTEINS; PANCREAS; PROTEINS; RECEPTORS, GROWTH FACTOR; SPLEEN; STOMACH; TRANS-ACTIVATORS;

EID: 0033869726     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Independent requirement for ISL1 in the formation of pancreatic mesenchyme and islet cells
2. Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas
3. Identification of human activin and TGF beta type I receptors that form heteromeric kinase complexes with type II receptors
4. Involvement of Sonic hedgehog (Shh) in mouse embryonic lung growth and morphogenesis
5. Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles
6. Expression of activin subunits, activin receptors and follistatin in postimplantation mouse embryos suggests specific developmental functions for different activins
7. Notochord repression of endodermal Sonic hedgehog permits pancreas development
8. Regulation of pancreas development by Hedgehog signaling
9. TGF-β signalling from cell membrane to nucleus through SMAD proteins
10. Dominant-negative Smad2 mutants inhibit activin/Vg1 signaling and disrupt axis formation in Xenopus
11. Pancreas development is promoted by cyclopamine, a Hedgehog signaling inhibitor
12. Notochord to endoderm signaling is required for pancreas development
13. Pancreas development in the chick embryo
14. Pancreatic-duodenal homeobox 1 -role in gastric endocrine patterning
15. A molecular pathway determining left-right asymmetry in chick embryogenesis
16. Sonic hedgehog is essential to foregut development
17. mRNAs for activin receptors II and IIB are expressed in mouse oocytes and in the epiblast of pre-gastrula and gastrula stage mouse embryos
18. Controlling TGF-β signaling
19. Different phenotypes for mice deficient in either activins or activin receptor type II
20. Regulation of anterior/posterior patterning of the axial skeleton by growth/differentiation factor 11
21. The signaling pathway mediated by the type IIB activin receptor controls axial patterning and lateral asymmetry in the mouse
22. α-Cell neogenesis in an animal model of IDDM
23. Sonic hedgehog regulates branching morphogenesis in the mammalian lung
24. Sonic hedgehog is an endodermal signal inducing BMP-4 and Hox genes during induction and regionalization of the chick hindgut
25. Five types of pyloric cells in the antral mucosa of the stomach
26. Ectodermal patterning in vertebrate embryos
27. Impaired differentiation of endocrine and exocrine cells of the pancreas in transgenic mouse expressing the truncated type II activin receptor
28. The type II activin receptors are essential for egg cylinder growth, gastrulation, and rostral head development in mice
29. Expression of type I and type IB receptors for activin in midgestation mouse embryos suggests distinct functions in organogenesis
30. Regulation of Smad activity
31. Hepatocyte nuclear factor 3β is involved in pancreatic beta-cell- specific transcription of the pdx-1 gene
32. Hypoplasia of pancreatic islets in transgenic mice expressing activin receptor mutants