Effect of reg protein on rat pancreatic ductal cells

Pancreas

Volumn 17, Issue 3, 1998, Pages 256-261

  Zenilman, Michael E ^a   Chen, Jian ^b   Magnuson, Thomas H ^b  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b NONE

Author keywords

BrdU incorporation; Pancreatic ductal cells; Pancreatic regenerating gene; Reg

Indexed keywords

AMYLASE; BROXURIDINE; CYTOKERATIN; INSULIN; INTRINSIC FACTOR; MITOGENIC AGENT; MONOCLONAL ANTIBODY; PROPIDIUM IODIDE; PROTEIN REG; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; IMMUNOFLUORESCENCE; MALE; MITOGENESIS; NONHUMAN; PANCREAS DUCT; PRIORITY JOURNAL; RAT; TISSUE REGENERATION;

EID: 0031662468     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006676-199810000-00005     Document Type: Article

References (37)

1. Watanabe T, Yonekura H, Terazono K, Yamamoto H, Okamoto H. Complete nucleotide sequence of human reg gene and its expression in normal and tumoral tissue. J Biol Chem 1990;265:7422-39.
2. Watanabe T, Yonemura Y, Yonekura H, et al. Pancreatic beta-cell replication and amelioration of surgical diabetes by Reg protein. Proc Natl Acad Sci USA 1994;91:3589-92.
3. Terazono K, Yamamoto H, Takasawa S, et al. A novel gene activated in regenerating islets. J Biol Chem 1988;263:2111-4.
4. Terazono K, Uchiyama Y, Ide M, Yatanabe T, Yonekura H, Yamamoto H, Okamoto H. Expression of reg gene in rat regenerating islets and its co-localization with insulin in the beta cell secretory granules. Diabetologia 1990;33:250-2.
5. Miyaura C, Chen L, Appel M, et al. Expression of reg/PSP, a pancreatic exocrine gene: relationship to changes in islet β-cell mass. Mol Endocrinol 1991;5:226-34.
6. Zenilman ME, Perfetti R, Swinson K, Magnuson TH, Shuldiner AR. Pancreatic regeneration (reg) gene expression in a rat model of islet hyperplasia. Surgery 1996;119:576-84.
7. Unno M, Yonekura H, Nakagawara K, et al. Structure, chromosomal localization and expression of mouse reg genes reg I and reg II. J Biol Chem 1993;268:15974-82.
8. Zenilman ME, Magnuson TH, Swinson K, Egan J, Perfetti R, Shuldiner AR. Pancreatic thread protein is mitogenic to pancreaticderived cells in culture. Gastroenterology 1996;110:1208-14.
9. Gross J, Carlson RI, Brauer AW, Margolies MN, Warshaw AL, Wands JR. Isolation, characterization, and distribution of an unusual pancreatic human secretory protein. J Clin Invest 1985;76: 2115-26.
10. Verme TB, Hootman SR. Regulation of pancreatic duct epithelial growth in vitro. Am J Physiol 1990;258:G833-40.
11. Bhattacharyya E, Panchal A, Wilkins TH, de Ondarza J, Hootman S. Insulin, transforming growth factors and substrates modulate growth of guinea pig pancreatic duct cells in vitro. Gastroenterology 1995;109:944-52.
12. Unaune EM, Braun J. Immunofluorescence methods. In: Weir DM, ed. Handbook of experimental immunology: immunochemistry. Boston: Blackwell Scientific, 1986.
13. Lee EY, Seetharam B, Alpers DH, DeSchryver-Kecskemeti K. Immunohistochemical survey of cobalamin-binding proteins. Gastroenterology 1992;97:1171-80.
14. Montrose-Rafizadeh C, Egan JM, Roth J. Incretin hormones regulate glucose-dependent insulin secretion in RIN 1046-38 cells: mechanisms of action. Endocrinology 1994;135:589-94.
15. Mozdziak PE, Fassel T, Gregory R, Schultz E, Greaser ML, Cassens RG. Quantitation of satellite cell proliferation in vivo using image analysis. Biotech Histochem 1994;69:249-52.
16. Fedarko N, Bianco P, Vetter U, Robey PG. Human bone cell enzyme expression and cellular heterogeneity: correlation of alkaline phosphatase enzyme activity with cell cycle. J Cell Physiol 1990;144:115-21.
17. Gross J, Brauer AW, Bringhurst RF, Corbett XX, Margolies MN. An unusual bovine pancreatic protein exhibiting pH-dependent globule-fibril transformation and unique amino acid sequence. Proc Natl Acad Sci USA 1985;82:5627-31.
18. Cai L, Harris WR, Marshak DR, Gross J, Crabb JW. Structural analysis of bovine pancreatic thread protein. J Prot Chem 1990;9: 623-32.
19. de Caro A, Lohse J, Sarles H. Characterization of a protein isolated from pancreatic calculi of men suffering from chronic calcifying pancreatitis. Biochem Biophys Res Commun 1979;87:1776-82.
20. Giorgi D, Bernard JP, Rouquier S, Iovanna J, Sarles H, Dagorn JC. Secretory pancreatic stone protein messenger RNA. J Clin Invest 1989;84:100-6.
21. Bernard JP, Adrich Z, Montalto G, et al. Immunoreactive forms of pancreatic stone protein in six mammalian species. Pancreas 1991; 6:162-7.
22. Orelle B, Keim V, Dagorn JC, Iovanna JL. Human pancreatitis associated protein: messenger RNA cloning and expression in pancreatic diseases. J Clin Invest 1992;90:2284-91.
23. Iovanna J, Orelle B, Keim V, Dagorn JC. Messenger RNA sequence and expression of rat pancreatitis associated protein, a lectin related protein overexpressed during acute experimental pancreatitis. J Biol Chem 1991;266:24664-9.
24. Vinik AI, Pittenger G, Rafaeloff R, Rosenberg L. Factors controlling pancreatic islet neogenesis. Tumor Biol 1993;14:184-200.
25. Perfetti R, Egan JM, Zenilman ME, Shuldiner AR. Expression of the regenerating gene in the pancreas of aging mice. Transplant Proc 1994;26:733.
26. Kim S, Zenilman ME, Levine BA, Steinberg JJ. Ectopic expression of reg protein: a marker of colorectal mucosa at risk for neoplasia. J Gastrointest Surg 1997;1:194-202.
27. Smith JP, Yelamarty RV, Kramer ST, Cheung JY. Effects of cholecystokinin on cytosolic calcium in pancreatic ducts segments and ductal cells. Am J Physiol 1993;27:G1177-83.
28. Bouwens L, Wang RN, De Blay E, Pipeleer DG, Kloppel G. Cytokeratins as markers of ductal cell differentiation and islet neogenesis in the neonatal rat pancreas. Diabetes 1994;43:1279-83.
29. Bonner-Weir S, Baxter LA, Schuppin GT, Smith FE. A second pathway for regeneration of adult exocrine and endocrine pancreas: a possible recapitulation of embryonic development. Diabetes 1993;42:1715-20.
30. Rao MS, Dwived RS, Yelandi AV, et al. Role of periductule and ductular epithelial cells of the adult rat pancreas in pancreatic hepatocyte lineage. Am J Pathol 1989;134:1069-86.
31. Edstrom C, Falkmer S. Qualitative and quantitative morphology of the rat pancreatic islet tissue five weeks after ligation of the pancreatic ducts. Acta Soc Med Ups 1967;72:376-90.
32. Hellerstrom C. The life story of the pancreatic β-cell. Diabetologia 1984;26:393-400.
33. Dudek RW, Lawrence IEJ, Hill RS, Johnson RC. Induction of islet cytodifferentiation by fetal mesenchyme in adult pancreatic ductal epithelium. Diabetes 1991;40:1041-8.
34. Yeo CJ, Bastidas JA, Schmeig RE, et al. Pancreatic structure and glucose tolerance in a longitudinal study of experimental pancreatitis-induced diabetes. Ann Surg 1989;210:150-8.
35. Idezuki Y, Goetz FC. Lillehei RC. Late effect of pancreatic duct ligation on β-cell function. Am J Surg 1969;117:33-9.
36. Kloppel G, Bommer G, Commandeur G, Heitz PU. The endocrine pancreas in chronic pancreatitis: immunocytochemical and ultrastructural studies. Virchows Arch 1978;377:157-74.
37. Dragstedt LR. Some physiologic problems in surgery of the pancreas. Ann Surg 1943;118:576-93.