The role of pregnane neurosteroids in ethanol withdrawal: Behavioral genetic approaches

Pharmacology and Therapeutics

Volumn 101, Issue 2, 2004, Pages 91-112

  Finn, Deborah A ^a   Ford, Matthew M ^b   Wiren, Kristine M ^b   Roselli, Charles E ^b   Crabbe, John C ^b  

^a PORTLAND VA MEDICAL CENTER   (United States)

^b NONE

Author keywords

Behavioral sensitivity; Biosynthetic enzymes; Functional sensitivity; GABAA receptor; Inbred strains; Selected lines

Indexed keywords

3BETA HYDROXY 5BETA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 5ALPHA PREGNANE 3,20 DIONE; 5BETA TETRAHYDRODEOXYCORTICOSTERONE; ALCOHOL; ALFAXALONE; ANTICONVULSIVE AGENT; BARBITURIC ACID DERIVATIVE; BENZODIAZEPINE DERIVATIVE; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CORTICOSTERONE; DIAZEPAM; ELTANOLONE; EPIALLOPREGNANOLONE; ESTRADIOL; FINASTERIDE; FLUOXETINE; ION CHANNEL; LIGAND; NEUROSTEROID; PREGNANE DERIVATIVE; PREGNANE NEUROSTEROID ALLOPREGNANOLONE; PROGESTERONE; STEROID 5ALPHA REDUCTASE; STEROID 5ALPHA REDUCTASE INHIBITOR; STEROIDOGENIC ACUTE REGULATORY PROTEIN; TETRAHYDRODEOXYCORTICOSTERONE; UNCLASSIFIED DRUG;

ALCOHOL WITHDRAWAL; ALCOHOLISM; ANTICONVULSANT ACTIVITY; ANXIETY DISORDER; BEHAVIOR GENETICS; BIOSYNTHESIS; BRAIN; CHLORIDE CURRENT; CHROMOSOME 11; CHROMOSOME 13; DEPRESSION; DISEASE SEVERITY; DRUG BLOOD LEVEL; DRUG DEPENDENCE; DRUG EFFECT; DRUG EFFICACY; DRUG POTENCY; DRUG TOLERANCE; ENZYME ACTIVITY; GENE INTERACTION; GENE MAPPING; GENETIC DIFFERENCE; GENETIC MODEL; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; MAJOR DEPRESSION; MEMORY DISORDER; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; SEIZURE; SEIZURE SUSCEPTIBILITY; SEX DIFFERENCE; STEROID BLOOD LEVEL; STEROIDOGENESIS; SYMPTOMATOLOGY; WITHDRAWAL SYNDROME;

EID: 0842324491     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2003.10.006     Document Type: Review

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