Brain allopregnanolone regulates the potency of the GABA(A) receptor agonist muscimol

Neuropharmacology

Volumn 39, Issue 3, 2000, Pages 440-448

  Pinna, G ^a   Uzunova, V ^b   Matsumoto, K ^c   Puia, G ^d   Mienville, J M ^b   Costa, E ^b   Guidotti, A ^b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY OF CHICAGO   (United States)

^c Toyama Medical and Pharmaceutical University   (Japan)

^d UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

5 Reductase; GABA(A) receptors; Muscimol; Neurosteroids; SKF 105,111

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR STIMULATING AGENT; MUSCIMOL; NEUROSTEROID; PREGNENOLONE; PROGESTERONE; SKF 105111; STEROID 5ALPHA REDUCTASE; STEROID 5ALPHA REDUCTASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; BRAIN; CEREBELLUM; CHLORIDE CURRENT; CONTROLLED STUDY; DOSE RESPONSE; DRUG METABOLISM; DRUG POTENCY; ELECTROPHYSIOLOGY; EVOKED RESPONSE; MALE; MOUSE; NONHUMAN; OLFACTORY BULB; PATCH CLAMP; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RIGHTING REFLEX;

5-ALPHA-DIHYDROPROGESTERONE; ANIMALS; BRAIN; ENZYME INHIBITORS; GABA AGONISTS; MALE; MICE; MUSCIMOL; PREGNANEDIONES; PREGNANOLONE; PYRAMIDAL CELLS; RECEPTORS, GABA-A; SYNAPTIC TRANSMISSION;

EID: 0033954998     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(99)00149-5     Document Type: Article

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