Fetal death in mice lacking 5α-reductase type 1 caused by estrogen excess

Molecular Endocrinology

Volumn 11, Issue 7, 1997, Pages 917-927

  Mahendroo, Mala S ^a   Cala, Kristine M ^a   Landrum, Charles P ^a   Russell, David W ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTENEDIONE; AROMATASE; STEROID 5ALPHA REDUCTASE; TESTOSTERONE;

ANDROGEN SYNTHESIS; ANDROSTENEDIONE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ESTROGEN SYNTHESIS; FETUS DEATH; FETUS WASTAGE; GESTATIONAL AGE; MOUSE; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; TESTOSTERONE BLOOD LEVEL;

ANDROSTENEDIONE; ANIMALS; BIOLOGICAL ASSAY; DECIDUA; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYONIC AND FETAL DEVELOPMENT; ESTROGEN ANTAGONISTS; ESTROGENS; FEMALE; FETAL DEATH; GENE EXPRESSION REGULATION, ENZYMOLOGIC; IN SITU HYBRIDIZATION; LITTER SIZE; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NITRILES; PLACENTA; RNA, MESSENGER; STEROIDS; TAMOXIFEN; TESTOSTERONE 5-ALPHA-REDUCTASE; TRIAZOLES; UTERUS;

ANIMALIA;

EID: 0030967604     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.11.7.917     Document Type: Article

References (41)

1. Russell DW, Wilson JD 1994 Steroid 5α-reductase: two genes/two enzymes. Annu Rev Biochem 63:25-61
2. Simpson ER, Mahendroo MS, Means GD, Kilgore MW, Hinshelwood MM, Graham-Lorence S, Amarneh B, Ito Y, Fisher CR, Michael MD, Mendelson CR, Bulun SE 1994 Aromatase cytochrome P450, the enzyme responsible for estrogen biosynthesis. Endocr Rev 15:342-355
3. AROM) deficiency. J Biol Chem 267:4781-5
4. Ito Y, Fisher CR, Conte FA, Grumbach MM, Simpson ER 1993 Molecular basis of aromatase deficiency in an adult female with sexual infantilism and polycystic ovaries. Proc Natl Acad Sci USA 90:11673-11677
5. Andersson S, Russell DW, Wilson JD 1996 17 β-Hydroxysteroid dehydrogenase 3 deficiency. Trends Endocrinol Metab 7:121-126
6. Wilson JD, Griffin JE, Russell DW 1993 Steroid 5α-reductase 2 deficiency. Endocr Rev 14:577-593
7. Milewich L, Mendonca BB, Arnhold I, Wallace AM, Donaldson MDC, Wilson JD, Russell DW 1995 Women with steroid 5α-reductase 2 deficiency have normal concentrations of plasma 5α-dihydroprogesterone during the luteal phase. J Clin Endocrin Metab 80:3136-3139
8. Thigpen AE, Silver RI, Guileyardo JM, Casey ML, McConnell JD, Russell DW 1993 Tissue distribution and ontogeny of steroid 5α-reductase isozyme expression. J Clin Invest 92:903-910
9. Mahendroo MS, Cala KM, Russell DW 1996 5α-Reduced androgens play a key role in murine parturition. Mol Endocrinol 10:380-392
10. Abrahamsohn PA, Zorn, TMT 1993 Implantation and decidualization in rodents. J Exp Zool 266:603-628
11. Soares MJ, Faria TN, Roby KF, Deb S 1991 Pregnancy and the prolactin family of hormones: coordination of anterior pituitary, uterine, and placental expression. Endocr Rev 12:402-423
12. Glasser SR, Julian J 1986 Intermediate filament protein as a marker of uterine stromal cell decidualization. Biol Reprod 35:463-474
13. Normington K, Russell DW 1992 Tissue distribution and kinetic characteristics of rat steroid 5α-reductase isozymes. Evidence for distinct physiological functions. J Biol Chem 267:19548-19554
14. Barkley MS, Michael SD, Geschwind II, Bradford GE 1977 Plasma testosterone during pregnancy in the mouse. Endocrinology 100:1472-1475
15. Barkley MS, Geschwind II, Bradford GE 1979 The gestational pattern of estradiol, testosterone and progesterone secretion in selected strains of mice. Biol Reprod 20:733-738
16. Soares MJ, Talamantes F 1982 Gestational effects on placental and serum androgen, progesterone and prolactin-like activity in the mouse. J Endocrinol 95:29-36
17. Soares MJ, Talamantes F 1983 Midpregnancy elevation of serum androstenedione levels in the C3H/HeN mouse: placental origin. Endocrinology 113:1408-1412
18. Gibori G, Chatterton RT, Chien JL 1979 Ovarian and serum concentrations of androgen throughout pregnancy in the rat. Biol Reprod 21:53-56
19. Wilson JD 1994 A new beginning for estrogen physiology. J Clin Invest 94:2176
20. Davis VL, Couse JF, Goulding EH, Power SGA, Eddy EM, Korach KS 1994 Aberrant reproductive phenotypes evident in transgenic mice expressing the wild-type mouse estrogen receptor. Endocrinology 135:379-386
21. Hickey GJ, Chen SA, Besman MJ, Shively JE, Hall PF, Gaddy-Kurten D, Richards JS 1988 Hormonal regulation, tissue distribution, and content of aromatase cytochrome P450 messenger ribonucleic acid and enzyme in rat ovarian follicles and corpora lutea: relationship to estradiol biosynthesis. Endocrinology 122:1426-1436
22. Doody KJ, Lephart ED, Stirling D, Lorence MC, Magness RR, McPhaul MJ, Simpson ER 1991 Expression of mRNA species encoding steroidogenic enzymes in the rat ovary. J Mol Endocrinol 6:153-162
23. Collins P 1996 Vascular aspects of oestrogen. Maturitas 23:217-226
24. Smith MG 1926 On the interruption of pregnancy in the rat by the injection of ovarian follicular extract. J Hopkins Hosp Bull 39:203-214
25. Huggett ASG, Pritchard JJ 1945 Experimental foetal death: the surviving placenta. Proc R Soc Med 38:261-266
26. Hain AM 1935 The physiology of pregnancy in the rat: An hormonal investigation into the mechanism of parturition. Effect on the female rat of the ante-natal administration of oestrin to the mother. J Exp Physiol 25:131-143
27. Kutteh WH, Carr BR 1993 Recurrent pregnancy loss. In: Carr BR, Blackwell RE (eds) Textbook of Reproductive Medicine. Appleton and Lange, Norwalk, CT, pp 559-579
28. Cunningham FG, MacDonald PC, Leveno KJ, Gant NF, Gilstrap LC 1993 The placental hormones. In: Williams Obstetrics, ed 19. Appleton and Lange, Norwalk, CT, pp 139-164
29. Jenkins EP, Hsieh C, Milatovich A, Normington K, Berman DM, Francke U, Russell DW 1991 Characterization and chromosomal mapping of a human steroid 5α-reductase gene and pseudogene and mapping of the mouse homologue. Genomics 11:1102-1112
30. Sambrook J, Fritsch EF, Maniatis T 1989 Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold spring Harbor, NY
31. Gunning P, Ponte P, Okayama H, Engel J, Blau H, Kedes L 1983 Isolation and characterization of full-length cDNA clones for human α-, β-, and γ-actin mRNAs: skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently removed. Mol Cell Biol 3:787-795
32. Keegan CE, Herman JP, Karolyi IJ, O'Shea KS, Camper SA, Seasholtz AF 1994 Differential expression of corticotropin-releasing hormone in developing mouse embryos and adult brain. Endocrinology 134:2547-2555
33. Colosi P, Talamantes F, Linzer DIH 1987 Molecular cloning and expression of mouse placental lactogen I complementary deoxyribonucleic acid. Mol Endocrinol 1:767-776
34. Jackson LL, Colosi P, Talamantes F, Linzer DIH 1986 Molecular cloning of mouse placental lactogen cDNA. Proc Natl Acad Sci USA 83:8496-8500
35. Linzer DI, Nathans D 1984 Nucleotide sequence of a growth-related mRNA encoding a member of the prolactin-growth hormone family. Proc Natl Acad Sci USA 81:4255-4259
36. White R, Lees JA, Needham M, Ham J, Parker MG 1987 Structural organization and expression of the mouse estrogen receptor. Mol Endocrinol 1:735-744
37. Hickey GJ, Krasnow JS, Beattie, WG, Richards, JS 1990 Aromatase cytochrome P450 in rat ovarian granulosa cells before and after luteinization: adenosine 3′,5′ monophosphate-dependent and independent regulation. Mol Endocrinol 4:3-12
38. Danielson PE, Forss-Peter S, Brow MA, Calavetta L, Douglass J, Milner RJ, Sutcliffe JG 1988 p1B15: a cDNA clone of the rat mRNA encoding cyclophilin. DNA 7:261-267
39. Harlow E, Lane D 1988 Antibodies, A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
40. Berman DM, Tian H, Russell DW 1995 Expression and regulation of steroid 5α-reductase in the urogenital tract of the fetal mice. Mol Endocrinol 9:1561-1570
41. Thigpen AE, Cala KM, Russell DW 1993 Characterization of chinese hamster ovary cell lines expressing human steroid 5α-reductase isozymes. J Biol Chem 268: 17404-17412