-
1
-
-
0037164865
-
Mitochondrial release of apoptosis-inducing factor occurs downstream of cytochrome c release in response to several proapoptotic stimuli
-
Arnoult D., Parone P., Martinou J.C., Antonsson B., Estaquier J., Arneisen J.C. Mitochondrial release of apoptosis-inducing factor occurs downstream of cytochrome c release in response to several proapoptotic stimuli. J. Cell Biol. 159:2002;923-929.
-
(2002)
J. Cell Biol.
, vol.159
, pp. 923-929
-
-
Arnoult, D.1
Parone, P.2
Martinou, J.C.3
Antonsson, B.4
Estaquier, J.5
Arneisen, J.C.6
-
2
-
-
0025854274
-
The double-edged role of nitric oxide in brain function and superoxide-mediated injury
-
Beckman J.S. The double-edged role of nitric oxide in brain function and superoxide-mediated injury. J. Dev. Physiol. 15:1991;53-59.
-
(1991)
J. Dev. Physiol.
, vol.15
, pp. 53-59
-
-
Beckman, J.S.1
-
3
-
-
0027280338
-
Pathological implications of nitric oxide, superoxide and peroxynitrite formation
-
Beckman J.S., Crow J.P. Pathological implications of nitric oxide, superoxide and peroxynitrite formation. Biochem. Soc. Trans. 21:1993;330-334.
-
(1993)
Biochem. Soc. Trans.
, vol.21
, pp. 330-334
-
-
Beckman, J.S.1
Crow, J.P.2
-
4
-
-
0019321840
-
ADP-ribosylation in mammalian cell ghosts. Dependence of poly(ADP-ribose) synthesis on strand breakage in DNA
-
Benjamin R.C., Gill D.M. ADP-ribosylation in mammalian cell ghosts. Dependence of poly(ADP-ribose) synthesis on strand breakage in DNA. J. Biol. Chem. 255:1980;10493-10501.
-
(1980)
J. Biol. Chem.
, vol.255
, pp. 10493-10501
-
-
Benjamin, R.C.1
Gill, D.M.2
-
5
-
-
0033047235
-
Apoptosis without caspases: An inefficient molecular guillotine
-
Borner C., Monney L. Apoptosis without caspases an inefficient molecular guillotine . Cell Death Differ. 6:1999;497-507.
-
(1999)
Cell Death Differ.
, vol.6
, pp. 497-507
-
-
Borner, C.1
Monney, L.2
-
6
-
-
0031871304
-
Inhibitors of the activity of poly (ADP-ribose) synthetase reduce the cell death caused by hydrogen peroxide in human cardiac myoblasts
-
Bowes J., Piper J., Thiemermann C. Inhibitors of the activity of poly (ADP-ribose) synthetase reduce the cell death caused by hydrogen peroxide in human cardiac myoblasts. Br. J. Pharmacol. 124:1998;1760-1766.
-
(1998)
Br. J. Pharmacol.
, vol.124
, pp. 1760-1766
-
-
Bowes, J.1
Piper, J.2
Thiemermann, C.3
-
7
-
-
0035890012
-
Apoptosis-inducing factor mediates microglial and neuronal apoptosis caused by pneumococcus
-
Braun J.S., Novak R., Murray P.J., Eischen C.M., Susin S.A., Kroemer G., Halle A., Weber J.R., Tuomanen E.I., Cleveland J.L. Apoptosis-inducing factor mediates microglial and neuronal apoptosis caused by pneumococcus. J. Infect. Dis. 184:2001;1300-1309.
-
(2001)
J. Infect. Dis.
, vol.184
, pp. 1300-1309
-
-
Braun, J.S.1
Novak, R.2
Murray, P.J.3
Eischen, C.M.4
Susin, S.A.5
Kroemer, G.6
Halle, A.7
Weber, J.R.8
Tuomanen, E.I.9
Cleveland, J.L.10
-
8
-
-
0036141405
-
Pneumococcal pneumolysin and H(2)O(2) mediate brain cell apoptosis during meningitis
-
Braun J.S., Sublett J.E., Freyer D., Mitchell T.J., Cleveland J.L., Tuomanen E.I., Weber J.R. Pneumococcal pneumolysin and H(2)O(2) mediate brain cell apoptosis during meningitis. J. Clin. Invest. 109:2002;19-27.
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 19-27
-
-
Braun, J.S.1
Sublett, J.E.2
Freyer, D.3
Mitchell, T.J.4
Cleveland, J.L.5
Tuomanen, E.I.6
Weber, J.R.7
-
9
-
-
0033011114
-
Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin
-
Burkart V., Wang Z.Q., Radons J., Heller B., Herceg Z., Stingl L., Wagner E.F., Kolb H. Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin. Nat. Med. 5:1999;314-319.
-
(1999)
Nat. Med.
, vol.5
, pp. 314-319
-
-
Burkart, V.1
Wang, Z.Q.2
Radons, J.3
Heller, B.4
Herceg, Z.5
Stingl, L.6
Wagner, E.F.7
Kolb, H.8
-
10
-
-
0032535275
-
Mitochondrial control of acute glutamate excitotoxicity in cultured cerebellar granule cells
-
Castilho R.F., Hansson O., Ward M.W., Budd S.L., Nicholls D.G. Mitochondrial control of acute glutamate excitotoxicity in cultured cerebellar granule cells. J. Neurosci. 18:1998;10277-10286.
-
(1998)
J. Neurosci.
, vol.18
, pp. 10277-10286
-
-
Castilho, R.F.1
Hansson, O.2
Ward, M.W.3
Budd, S.L.4
Nicholls, D.G.5
-
11
-
-
0037067597
-
Cell biology. PARP-1 - A perpetrator of apoptotic cell death
-
Chiarugi A., Moskowitz M.A. Cell biology. PARP-1 - a perpetrator of apoptotic cell death. Science. 297:2002;200-201.
-
(2002)
Science
, vol.297
, pp. 200-201
-
-
Chiarugi, A.1
Moskowitz, M.A.2
-
12
-
-
0030574060
-
Benzamide, an inhibitor of poly(ADP-ribose) polymerase, attenuates methamphetamine-induced dopamine neurotoxicity in the C57B1/6N mouse
-
Cosi C., Chopin P., Marien M. Benzamide, an inhibitor of poly(ADP-ribose) polymerase, attenuates methamphetamine-induced dopamine neurotoxicity in the C57B1/6N mouse. Brain Res. 735:1996;343-348.
-
(1996)
Brain Res.
, vol.735
, pp. 343-348
-
-
Cosi, C.1
Chopin, P.2
Marien, M.3
-
13
-
-
0030581308
-
Poly(ADP-ribose) polymerase inhibitors protect against MPTP-induced depletions of striatal dopamine and cortical noradrenaline in C57B1/6 mice
-
Cosi C., Colpaert F., Koek W., Degryse A., Marien M. Poly(ADP-ribose) polymerase inhibitors protect against MPTP-induced depletions of striatal dopamine and cortical noradrenaline in C57B1/6 mice. Brain Res. 729:1996;264-269.
-
(1996)
Brain Res.
, vol.729
, pp. 264-269
-
-
Cosi, C.1
Colpaert, F.2
Koek, W.3
Degryse, A.4
Marien, M.5
-
14
-
-
0032569674
-
Decreases in mouse brain NAD+ and ATP induced by 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP): Prevention by the poly(ADP-ribose) polymerase inhibitor, benzamide
-
Cosi C., Marien M. Decreases in mouse brain NAD+ and ATP induced by 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP) prevention by the poly(ADP-ribose) polymerase inhibitor, benzamide . Brain Res. 809:1998;58-67.
-
(1998)
Brain Res.
, vol.809
, pp. 58-67
-
-
Cosi, C.1
Marien, M.2
-
15
-
-
0027990790
-
Poly(ADP-ribose) polymerase: Early involvement in glutamate-induced neurotoxicity in cultured cerebellar granule cells
-
Cosi C., Suzuki H., Milani D., Facci L., Menegazzi M., Vantini G., Kanai Y., Skaper S.D. Poly(ADP-ribose) polymerase early involvement in glutamate-induced neurotoxicity in cultured cerebellar granule cells . J. Neurosci. Res. 39:1994;38-46.
-
(1994)
J. Neurosci. Res.
, vol.39
, pp. 38-46
-
-
Cosi, C.1
Suzuki, H.2
Milani, D.3
Facci, L.4
Menegazzi, M.5
Vantini, G.6
Kanai, Y.7
Skaper, S.D.8
-
16
-
-
0036323443
-
Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death
-
Cregan S.P., Fortin A., MacLaurin J.G., Callaghan S.M., Cecconi F., Yu S.W., Dawson T.M., Dawson V.L., Park D.S., Kroemer G., Slack R.S. Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death. J. Cell Biol. 158:2002;507-517.
-
(2002)
J. Cell Biol.
, vol.158
, pp. 507-517
-
-
Cregan, S.P.1
Fortin, A.2
MacLaurin, J.G.3
Callaghan, S.M.4
Cecconi, F.5
Yu, S.W.6
Dawson, T.M.7
Dawson, V.L.8
Park, D.S.9
Kroemer, G.10
Slack, R.S.11
-
17
-
-
0034617449
-
Apoptosis-inducing factor (AIF): A ubiquitous mitochondrial oxidoreductase involved in apoptosis
-
Daugas E., Nochy D., Ravagnan L., Loeffler M., Susin S.A., Zamzami N., Kroemer G. Apoptosis-inducing factor (AIF) a ubiquitous mitochondrial oxidoreductase involved in apoptosis . FEBS Lett. 476:2000;118-123.
-
(2000)
FEBS Lett.
, vol.476
, pp. 118-123
-
-
Daugas, E.1
Nochy, D.2
Ravagnan, L.3
Loeffler, M.4
Susin, S.A.5
Zamzami, N.6
Kroemer, G.7
-
18
-
-
0034117177
-
Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis
-
Daugas E., Susin S.A., Zamzami N., Ferri K.F., Irinopoulou T., Larochette N., Prevost M.C., Leber B., Andrews D., Penninger J., Kroemer G. Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis. FASEB J. 14:2000;729-739.
-
(2000)
FASEB J.
, vol.14
, pp. 729-739
-
-
Daugas, E.1
Susin, S.A.2
Zamzami, N.3
Ferri, K.F.4
Irinopoulou, T.5
Larochette, N.6
Prevost, M.C.7
Leber, B.8
Andrews, D.9
Penninger, J.10
Kroemer, G.11
-
19
-
-
0035425899
-
Importance of poly(ADP-ribose) glycohydrolase in the control of poly(ADP-ribose) metabolism
-
Davidovic L., Vodenicharov M., Affar E.B., Poirier G.G. Importance of poly(ADP-ribose) glycohydrolase in the control of poly(ADP-ribose) metabolism. Exp. Cell Res. 268:2001;7-13.
-
(2001)
Exp. Cell Res.
, vol.268
, pp. 7-13
-
-
Davidovic, L.1
Vodenicharov, M.2
Affar, E.B.3
Poirier, G.G.4
-
20
-
-
0027178135
-
Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures
-
Dawson V.L., Dawson T.M., Bartley D.A., Uhl G.R., Snyder S.H. Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures. J. Neurosci. 13:1993;2651-2661.
-
(1993)
J. Neurosci.
, vol.13
, pp. 2651-2661
-
-
Dawson, V.L.1
Dawson, T.M.2
Bartley, D.A.3
Uhl, G.R.4
Snyder, S.H.5
-
21
-
-
0025773785
-
Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures
-
Dawson V.L., Dawson T.M., London E.D., Bredt D.S., Snyder S.H. Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures. Proc. Natl. Acad. Sci. USA. 88:1991;6368-6371.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 6368-6371
-
-
Dawson, V.L.1
Dawson, T.M.2
London, E.D.3
Bredt, D.S.4
Snyder, S.H.5
-
22
-
-
0029927787
-
Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice
-
Dawson V.L., Kizushi V.M., Huang P.L., Snyder S.H., Dawson T.M. Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice. J. Neurosci. 16:1996;2479-2487.
-
(1996)
J. Neurosci.
, vol.16
, pp. 2479-2487
-
-
Dawson, V.L.1
Kizushi, V.M.2
Huang, P.L.3
Snyder, S.H.4
Dawson, T.M.5
-
24
-
-
0028113249
-
Structure and function of poly(ADP-ribose) polymerase
-
de Murcia G., Schreiber V., Molinete M., Saulier B., Poch O., Masson M., Niedergang C., Menissier de Murcia J. Structure and function of poly(ADP-ribose) polymerase. Mol. Cell. Biochem. 138:1994;15-24.
-
(1994)
Mol. Cell. Biochem.
, vol.138
, pp. 15-24
-
-
De Murcia, G.1
Schreiber, V.2
Molinete, M.3
Saulier, B.4
Poch, O.5
Masson, M.6
Niedergang, C.7
Menissier De Murcia, J.8
-
25
-
-
0035850884
-
Long-term neuroprotective effect of inhibiting poly(ADP-ribose) polymerase in rats with middle cerebral artery occlusion using a behavioral assessment
-
Ding Y., Zhou Y., Lai Q., Li J., Gordon V., Diaz F.G. Long-term neuroprotective effect of inhibiting poly(ADP-ribose) polymerase in rats with middle cerebral artery occlusion using a behavioral assessment. Brain Res. 915:2001;210-217.
-
(2001)
Brain Res.
, vol.915
, pp. 210-217
-
-
Ding, Y.1
Zhou, Y.2
Lai, Q.3
Li, J.4
Gordon, V.5
Diaz, F.G.6
-
26
-
-
0034069736
-
Poly(ADP- ribose) synthase inhibition reduces ischemic injury and inflammation in neonatal rat brain
-
Ducrocq S., Benjelloun N., Plotkine M., Ben-Ari Y., Charriaut-Marlangue C. Poly(ADP- ribose) synthase inhibition reduces ischemic injury and inflammation in neonatal rat brain. J. Neurochem. 74:2000;2504-2511.
-
(2000)
J. Neurochem.
, vol.74
, pp. 2504-2511
-
-
Ducrocq, S.1
Benjelloun, N.2
Plotkine, M.3
Ben-Ari, Y.4
Charriaut-Marlangue, C.5
-
27
-
-
0034254734
-
Caspase-independent commitment phase to apoptosis in activated blood T lymphocytes: Reversibility at low apoptotic insult
-
Dumont C., Durrbach A., Bidere N., Rouleau M., Kroemer G., Bernard G., Hirsch F., Charpentier B., Susin S.A., Senik A. Caspase-independent commitment phase to apoptosis in activated blood T lymphocytes reversibility at low apoptotic insult . Blood. 96:2000;1030-1038.
-
(2000)
Blood
, vol.96
, pp. 1030-1038
-
-
Dumont, C.1
Durrbach, A.2
Bidere, N.3
Rouleau, M.4
Kroemer, G.5
Bernard, G.6
Hirsch, F.7
Charpentier, B.8
Susin, S.A.9
Senik, A.10
-
28
-
-
0030842946
-
Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia
-
Eliasson M.J., Sampei K., Mandir A.S., Hurn P.D., Traystman R.J., Bao J., Pieper A., Wang Z.Q., Dawson T.M., Snyder S.H., Dawson V.L. Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia. Nat. Med. 3:1997;1089-1095.
-
(1997)
Nat. Med.
, vol.3
, pp. 1089-1095
-
-
Eliasson, M.J.1
Sampei, K.2
Mandir, A.S.3
Hurn, P.D.4
Traystman, R.J.5
Bao, J.6
Pieper, A.7
Wang, Z.Q.8
Dawson, T.M.9
Snyder, S.H.10
Dawson, V.L.11
-
29
-
-
0030832874
-
Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase
-
Endres M., Wang Z.Q., Namura S., Waeber C., Moskowitz M.A. Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase. J. Cereb. Blood Flow Metab. 17:1997;1143-1151.
-
(1997)
J. Cereb. Blood Flow Metab.
, vol.17
, pp. 1143-1151
-
-
Endres, M.1
Wang, Z.Q.2
Namura, S.3
Waeber, C.4
Moskowitz, M.A.5
-
30
-
-
0034676090
-
Apoptosis control in syncytia induced by the HIV type 1-envelope glycoprotein complex: Role of mitochondria and caspases
-
Ferri K.F., Jacotot E., Blanco J., Este J.A., Zamzami N., Susin S.A., Xie Z., Brothers G., Reed J.C., Penninger J.M., Kroemer G. Apoptosis control in syncytia induced by the HIV type 1-envelope glycoprotein complex role of mitochondria and caspases . J. Exp. Med. 192:2000;1081-1092.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1081-1092
-
-
Ferri, K.F.1
Jacotot, E.2
Blanco, J.3
Este, J.A.4
Zamzami, N.5
Susin, S.A.6
Xie, Z.7
Brothers, G.8
Reed, J.C.9
Penninger, J.M.10
Kroemer, G.11
-
31
-
-
0036836070
-
Translocation of apoptosis-inducing factor in cerebellar granule cells exposed to neurotoxic agents inducing oxidative stress
-
Fonfria E., Dare E., Benelli M., Sunol C., Ceccatelli S. Translocation of apoptosis-inducing factor in cerebellar granule cells exposed to neurotoxic agents inducing oxidative stress. Eur. J. Neurosci. 16:2002;2013-2016.
-
(2002)
Eur. J. Neurosci.
, vol.16
, pp. 2013-2016
-
-
Fonfria, E.1
Dare, E.2
Benelli, M.3
Sunol, C.4
Ceccatelli, S.5
-
32
-
-
0034669944
-
Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria
-
Genini D., Adachi S., Chao Q., Rose D.W., Carrera C.J., Cottam H.B., Carson D.A., Leoni L.M. Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria. Blood. 96:2000;3537-3543.
-
(2000)
Blood
, vol.96
, pp. 3537-3543
-
-
Genini, D.1
Adachi, S.2
Chao, Q.3
Rose, D.W.4
Carrera, C.J.5
Cottam, H.B.6
Carson, D.A.7
Leoni, L.M.8
-
33
-
-
0033214624
-
Cleavage of utomodified poly(ADP-ribose) polymerase during apoptosis. Evidence for involvement of caspase-7
-
Germain M., Affar E.B., D'Amours D., Dixit V.M., Salvesen G.S., Poirier G.G. Cleavage of utomodified poly(ADP-ribose) polymerase during apoptosis. Evidence for involvement of caspase-7. J. Biol. Chem. 274:1999;28379-28384.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 28379-28384
-
-
Germain, M.1
Affar, E.B.2
D'Amours, D.3
Dixit, V.M.4
Salvesen, G.S.5
Poirier, G.G.6
-
34
-
-
0034949086
-
Characterization of the necrotic cleavage of poly(ADP-ribose) polymerase (PARP-1): Implication of lysosomal proteases
-
Gobeil S., Boucher C.C., Nadeau D., Poirier G.G. Characterization of the necrotic cleavage of poly(ADP-ribose) polymerase (PARP-1) implication of lysosomal proteases . Cell Death Differ. 8:2001;588-594.
-
(2001)
Cell Death Differ.
, vol.8
, pp. 588-594
-
-
Gobeil, S.1
Boucher, C.C.2
Nadeau, D.3
Poirier, G.G.4
-
35
-
-
0036218940
-
Poly(ADP-ribose) polymerase impairs early and long-term experimental stroke recovery
-
Goto S., Xue R., Sugo N., Sawada M., Blizzard K.K., Poitras M.F., Johns D.C., Dawson T.M., Dawson V.L., Crain B.J., Traystman R.J., Mori S., Hurn P.D. Poly(ADP-ribose) polymerase impairs early and long-term experimental stroke recovery. Stroke. 33:2002;1101-1106.
-
(2002)
Stroke
, vol.33
, pp. 1101-1106
-
-
Goto, S.1
Xue, R.2
Sugo, N.3
Sawada, M.4
Blizzard, K.K.5
Poitras, M.F.6
Johns, D.C.7
Dawson, T.M.8
Dawson, V.L.9
Crain, B.J.10
Traystman, R.J.11
Mori, S.12
Hurn, P.D.13
-
36
-
-
5544244721
-
Mitochondrial release of apoptosis-inducing factor and cytochrome c during smooth muscle cell apoptosis
-
Granville D.J., Cassidy B.A., Ruehlmann D.O., Choy J.C., Brenner C., Kroemer G., van Breemen C., Margaron P., Hunt D.W., McManus B.M. Mitochondrial release of apoptosis-inducing factor and cytochrome c during smooth muscle cell apoptosis. Am. J. Pathol. 159:2001;305-311.
-
(2001)
Am. J. Pathol.
, vol.159
, pp. 305-311
-
-
Granville, D.J.1
Cassidy, B.A.2
Ruehlmann, D.O.3
Choy, J.C.4
Brenner, C.5
Kroemer, G.6
Van Breemen, C.7
Margaron, P.8
Hunt, D.W.9
McManus, B.M.10
-
37
-
-
0033598713
-
Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion
-
Ha H.C., Snyder S.H. Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion. Proc. Natl. Acad. Sci. USA. 96:1999;13978-13982.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 13978-13982
-
-
Ha, H.C.1
Snyder, S.H.2
-
38
-
-
0033830186
-
Poly(ADP-ribose) polymerase-1 in the nervous system
-
Ha H.C., Snyder S.H. Poly(ADP-ribose) polymerase-1 in the nervous system. Neurobiol. Dis. 7:2000;225-239.
-
(2000)
Neurobiol. Dis.
, vol.7
, pp. 225-239
-
-
Ha, H.C.1
Snyder, S.H.2
-
39
-
-
0033601325
-
Survival and proliferation of cells expressing caspase-uncleavable poly(ADP-ribose) polymerase in response to death-inducing DNA damage by an alkylating agent
-
Halappanavar S.S., Rhun Y.L., Mounir S., Martins L.M., Huot J., Earnshaw W.C., Shah G.M. Survival and proliferation of cells expressing caspase-uncleavable poly(ADP-ribose) polymerase in response to death-inducing DNA damage by an alkylating agent. J. Biol. Chem. 274:1999;37097-37104.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37097-37104
-
-
Halappanavar, S.S.1
Rhun, Y.L.2
Mounir, S.3
Martins, L.M.4
Huot, J.5
Earnshaw, W.C.6
Shah, G.M.7
-
40
-
-
0029017038
-
Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells
-
Heller B., Wang Z.Q., Wagner E.F., Radons J., Burkle A., Fehsel K., Burkart V., Kolb H. Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells. J. Biol. Chem. 270:1995;11176-11180.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 11176-11180
-
-
Heller, B.1
Wang, Z.Q.2
Wagner, E.F.3
Radons, J.4
Burkle, A.5
Fehsel, K.6
Burkart, V.7
Kolb, H.8
-
41
-
-
0034641918
-
The biochemistry of apoptosis
-
Hengartner M.O. The biochemistry of apoptosis. Nature. 407:2000;770-776.
-
(2000)
Nature
, vol.407
, pp. 770-776
-
-
Hengartner, M.O.1
-
42
-
-
0033003004
-
Failure of poly(ADP-ribose) polymerase cleavage by caspases leads to induction of necrosis and enhanced apoptosis
-
Herceg Z., Wang Z.Q. Failure of poly(ADP-ribose) polymerase cleavage by caspases leads to induction of necrosis and enhanced apoptosis. Mol. Cell. Biol. 19:1999;5124-5133.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 5124-5133
-
-
Herceg, Z.1
Wang, Z.Q.2
-
43
-
-
18644377709
-
Critical role of photoreceptor apoptosis in functional damage after retinal detachment
-
Hisatomi T., Sakamoto T., Goto Y., Yamanaka I., Oshima Y., Hata Y., Ishibashi T., Inomata H., Susin S.A., Kroemer G. Critical role of photoreceptor apoptosis in functional damage after retinal detachment. Curr. Eye Res. 24:2002;161-172.
-
(2002)
Curr. Eye Res.
, vol.24
, pp. 161-172
-
-
Hisatomi, T.1
Sakamoto, T.2
Goto, Y.3
Yamanaka, I.4
Oshima, Y.5
Hata, Y.6
Ishibashi, T.7
Inomata, H.8
Susin, S.A.9
Kroemer, G.10
-
44
-
-
0032104095
-
Hydrogen peroxide-induced motoneuron apoptosis is prevented by poly ADP ribosyl synthetase inhibitors
-
Hivert B., Cerruti C., Camu W. Hydrogen peroxide-induced motoneuron apoptosis is prevented by poly ADP ribosyl synthetase inhibitors. Neuroreport. 9:1998;1835-1838.
-
(1998)
Neuroreport
, vol.9
, pp. 1835-1838
-
-
Hivert, B.1
Cerruti, C.2
Camu, W.3
-
45
-
-
0034795536
-
Apoptosis and necrosis occurring in excitotoxic cell death in isolated chick embryo retina
-
Ientile R., Macaione V., Teletta M., Pedale S., Torre V., Macaione S. Apoptosis and necrosis occurring in excitotoxic cell death in isolated chick embryo retina. J. Neurochem. 79:2001;71-78.
-
(2001)
J. Neurochem.
, vol.79
, pp. 71-78
-
-
Ientile, R.1
MacAione, V.2
Teletta, M.3
Pedale, S.4
Torre, V.5
MacAione, S.6
-
46
-
-
0035967169
-
Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death
-
Joza N., Susin S.A., Daugas E., Stanford W.L., Cho S.K., Li C.Y., Sasaki T., Elia A.J., Cheng H.Y., Ravagnan L., Ferri K.F., Zamzami N., Wakeham A., Hakem R., Yoshida H., Kong Y.Y., Mak T.W., Zuniga-Pflucker J.C., Kroemer G., Penninger J.M. Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death. Nature. 410:2001;549-554.
-
(2001)
Nature
, vol.410
, pp. 549-554
-
-
Joza, N.1
Susin, S.A.2
Daugas, E.3
Stanford, W.L.4
Cho, S.K.5
Li, C.Y.6
Sasaki, T.7
Elia, A.J.8
Cheng, H.Y.9
Ravagnan, L.10
Ferri, K.F.11
Zamzami, N.12
Wakeham, A.13
Hakem, R.14
Yoshida, H.15
Kong, Y.Y.16
Mak, T.W.17
Zuniga-Pflucker, J.C.18
Kroemer, G.19
Penninger, J.M.20
more..
-
47
-
-
0035929591
-
TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression
-
Kaminker P.G., Kim S.H., Taylor R.D., Zebarjadian Y., Funk W.D., Morin G.B., Yaswen P., Campisi J. TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression. J. Biol. Chem. 276:2001;35891-35899.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 35891-35899
-
-
Kaminker, P.G.1
Kim, S.H.2
Taylor, R.D.3
Zebarjadian, Y.4
Funk, W.D.5
Morin, G.B.6
Yaswen, P.7
Campisi, J.8
-
48
-
-
0027255417
-
Specific proteolytic cleavage of poly(ADP-ribose) polymerase: An early marker of chemotherapy-induced apoptosis
-
Kaufmann S.H., Desnoyers S., Ottaviano Y., Davidson N.E., Poirier G.G. Specific proteolytic cleavage of poly(ADP-ribose) polymerase an early marker of chemotherapy-induced apoptosis . Cancer Res. 53:1993;3976-3985.
-
(1993)
Cancer Res.
, vol.53
, pp. 3976-3985
-
-
Kaufmann, S.H.1
Desnoyers, S.2
Ottaviano, Y.3
Davidson, N.E.4
Poirier, G.G.5
-
49
-
-
0015383455
-
Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
-
Kerr J.F., Wyllie A.H., Currie A.R. Apoptosis a basic biological phenomenon with wide-ranging implications in tissue kinetics . Br. J. Cancer. 26:1972;239-257.
-
(1972)
Br. J. Cancer
, vol.26
, pp. 239-257
-
-
Kerr, J.F.1
Wyllie, A.H.2
Currie, A.R.3
-
50
-
-
0037179691
-
The harlequin mouse mutation downregulates apoptosis-inducing factor
-
Klein J.A., Longo-Guess C.M., Rossmann M.P., Seburn K.L., Hurd R.E., Frankel W.N., Bronson R.T., Ackerman S.L. The harlequin mouse mutation downregulates apoptosis-inducing factor. Nature. 419:2002;367-374.
-
(2002)
Nature
, vol.419
, pp. 367-374
-
-
Klein, J.A.1
Longo-Guess, C.M.2
Rossmann, M.P.3
Seburn, K.L.4
Hurd, R.E.5
Frankel, W.N.6
Bronson, R.T.7
Ackerman, S.L.8
-
51
-
-
0034666267
-
Omocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity
-
Kruman I.I., Culmsee C., Chan S.L., Kruman Y., Guo Z., Penix L., Mattson M.P. omocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity. J. Neurosci. 20:2000;6920-6926.
-
(2000)
J. Neurosci.
, vol.20
, pp. 6920-6926
-
-
Kruman, I.I.1
Culmsee, C.2
Chan, S.L.3
Kruman, Y.4
Guo, Z.5
Penix, L.6
Mattson, M.P.7
-
52
-
-
85047679198
-
The oxygen free radical system: From equations through membrane-protein interactions to cardiovascular injury and protection
-
Kukreja R.C., Hess M.L. The oxygen free radical system from equations through membrane-protein interactions to cardiovascular injury and protection . Cardiovasc. Res. 26:1992;641-655.
-
(1992)
Cardiovasc. Res.
, vol.26
, pp. 641-655
-
-
Kukreja, R.C.1
Hess, M.L.2
-
53
-
-
0035063766
-
Pharmacologic inhibition of poly(ADP-ribose) polymerase is neuroprotective following traumatic brain injury in rats
-
LaPlaca M.C., Zhang J., Raghupathi R., Li J.H., Smith F., Bareyre F.M., Snyder S.H., Graham D.I., McIntosh T.K. Pharmacologic inhibition of poly(ADP-ribose) polymerase is neuroprotective following traumatic brain injury in rats. J. Neurotrauma. 18:2001;369-376.
-
(2001)
J. Neurotrauma
, vol.18
, pp. 369-376
-
-
Laplaca, M.C.1
Zhang, J.2
Raghupathi, R.3
Li, J.H.4
Smith, F.5
Bareyre, F.M.6
Snyder, S.H.7
Graham, D.I.8
McIntosh, T.K.9
-
54
-
-
0027234752
-
Molecular and biochemical features of poly (ADP-ribose) metabolism
-
Lautier D., Lagueux J., Thibodeau J., Menard L., Poirier G.G. Molecular and biochemical features of poly (ADP-ribose) metabolism. Mol. Cell. Biochem. 122:1993;171-193.
-
(1993)
Mol. Cell. Biochem.
, vol.122
, pp. 171-193
-
-
Lautier, D.1
Lagueux, J.2
Thibodeau, J.3
Menard, L.4
Poirier, G.G.5
-
55
-
-
0028102478
-
Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE
-
Lazebnik Y.A., Kaufmann S.H., Desnoyers S., Poirier G.G., Earnshaw W.C. Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Nature. 371:1994;346-347.
-
(1994)
Nature
, vol.371
, pp. 346-347
-
-
Lazebnik, Y.A.1
Kaufmann, S.H.2
Desnoyers, S.3
Poirier, G.G.4
Earnshaw, W.C.5
-
56
-
-
0035433420
-
Four deaths and a funeral: From caspases to alternative mechanisms
-
Leist M., Jaattela M. Four deaths and a funeral from caspases to alternative mechanisms . Nat. Rev. Mol. Cell. Biol. 2:2001;589-598.
-
(2001)
Nat. Rev. Mol. Cell. Biol.
, vol.2
, pp. 589-598
-
-
Leist, M.1
Jaattela, M.2
-
58
-
-
0031575931
-
Apoptosis in the absence of poly-(ADP-ribose) polymerase
-
Leist M., Single B., Kunstle G., Volbracht C., Hentze H., Nicotera P. Apoptosis in the absence of poly-(ADP-ribose) polymerase. Biochem. Biophys. Res. Commun. 233:1997;518-522.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.233
, pp. 518-522
-
-
Leist, M.1
Single, B.2
Kunstle, G.3
Volbracht, C.4
Hentze, H.5
Nicotera, P.6
-
59
-
-
0035811496
-
Endonuclease G is an apoptotic DNase when released from mitochondria
-
Li L.Y., Luo X., Wang X. Endonuclease G is an apoptotic DNase when released from mitochondria. Nature. 412:2001;95-99.
-
(2001)
Nature
, vol.412
, pp. 95-99
-
-
Li, L.Y.1
Luo, X.2
Wang, X.3
-
60
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li P., Nijhawan D., Budihardjo I., Srinivasula S.M., Ahmad M., Alnemri E.S., Wang X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell. 91:1997;479-489.
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
Wang, X.7
-
61
-
-
0028865245
-
Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaks
-
Lindahl T., Satoh M.S., Poirier G.G., Klungland A. Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaks. Trends Biochem. Sci. 20:1995;405-411.
-
(1995)
Trends Biochem. Sci.
, vol.20
, pp. 405-411
-
-
Lindahl, T.1
Satoh, M.S.2
Poirier, G.G.3
Klungland, A.4
-
62
-
-
0036850176
-
Molecular mechanisms of sulfasalazine-induced T-cell apoptosis
-
Liptay S., Fulda S., Schanbacher M., Bourteele S., Ferri K.F., Kroemer G., Adler G., Debatin K.M., Schmid R.M. Molecular mechanisms of sulfasalazine-induced T-cell apoptosis. Br. J. Pharmacol. 137:2002;608-620.
-
(2002)
Br. J. Pharmacol.
, vol.137
, pp. 608-620
-
-
Liptay, S.1
Fulda, S.2
Schanbacher, M.3
Bourteele, S.4
Ferri, K.F.5
Kroemer, G.6
Adler, G.7
Debatin, K.M.8
Schmid, R.M.9
-
63
-
-
0031946532
-
Inhibition of poly(ADP-ribose) polymerase: Reduction of ischemic injury and attenuation of N-methyl-D-aspartate-induced neurotransmitter dysregulation
-
Lo E.H., Bosque-Hamilton P., Meng W. Inhibition of poly(ADP-ribose) polymerase reduction of ischemic injury and attenuation of N-methyl-D-aspartate- induced neurotransmitter dysregulation . Stroke. 29:1998;830-836.
-
(1998)
Stroke
, vol.29
, pp. 830-836
-
-
Lo, E.H.1
Bosque-Hamilton, P.2
Meng, W.3
-
64
-
-
0035078404
-
Dominant cell death induction by extramitochondrially targeted apoptosis-inducing factor
-
Loeffler M., Daugas E., Susin S.A., Zamzami N., Metivier D., Nieminen A.L., Brothers G., Penninger J.M., Kroemer G. Dominant cell death induction by extramitochondrially targeted apoptosis-inducing factor. FASEB J. 15:2001;758-767.
-
(2001)
FASEB J.
, vol.15
, pp. 758-767
-
-
Loeffler, M.1
Daugas, E.2
Susin, S.A.3
Zamzami, N.4
Metivier, D.5
Nieminen, A.L.6
Brothers, G.7
Penninger, J.M.8
Kroemer, G.9
-
65
-
-
0036179194
-
Excitotoxicity: Perspectives based on N-methyl-D-aspartate receptor subtypes
-
Lynch D.R., Guttmann R.P. Excitotoxicity perspectives based on N-methyl-D-aspartate receptor subtypes . J. Pharmacol. Exp. Ther. 300:2002;717-723.
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.300
, pp. 717-723
-
-
Lynch, D.R.1
Guttmann, R.P.2
-
66
-
-
0036689835
-
Biochemical and molecular basis of thimerosal-induced apoptosis in T cells: A major role of mitochondrial pathway
-
Makani S., Gollapudi S., Yel L., Chiplunkar S., Gupta S. Biochemical and molecular basis of thimerosal-induced apoptosis in T cells a major role of mitochondrial pathway . Genes Immun. 3:2002;270-278.
-
(2002)
Genes Immun.
, vol.3
, pp. 270-278
-
-
Makani, S.1
Gollapudi, S.2
Yel, L.3
Chiplunkar, S.4
Gupta, S.5
-
67
-
-
0034329823
-
NMDA but not non-NMDA excitotoxicity is mediated by poly(ADP-ribose) polymerase
-
Mandir A.S., Poitras M.F., Berliner A.R., Herring W.J., Guastella D.B., Feldman A., Poirier G.G., Wang Z.Q., Dawson T.M., Dawson V.L. NMDA but not non-NMDA excitotoxicity is mediated by poly(ADP-ribose) polymerase. J. Neurosci. 20:2000;8005-8011.
-
(2000)
J. Neurosci.
, vol.20
, pp. 8005-8011
-
-
Mandir, A.S.1
Poitras, M.F.2
Berliner, A.R.3
Herring, W.J.4
Guastella, D.B.5
Feldman, A.6
Poirier, G.G.7
Wang, Z.Q.8
Dawson, T.M.9
Dawson, V.L.10
-
68
-
-
0033545925
-
Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism
-
Mandir A.S., Przedborski S., Jackson-Lewis V., Wang Z.Q., Simbulan-Rosenthal C.M., Smulson M.E., Hoffman B.E., Guastella D.B., Dawson V.L., Dawson T.M. Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism. Proc. Natl. Acad. Sci. USA. 96:1999;5774-5779.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 5774-5779
-
-
Mandir, A.S.1
Przedborski, S.2
Jackson-Lewis, V.3
Wang, Z.Q.4
Simbulan-Rosenthal, C.M.5
Smulson, M.E.6
Hoffman, B.E.7
Guastella, D.B.8
Dawson, V.L.9
Dawson, T.M.10
-
70
-
-
13044270976
-
Poly(ADP-ribose) polymerase gene disruption conferred mice resistant to streptozotocin-induced diabetes
-
Masutani M., Suzuki H., Kamada N., Watanabe M., Ueda O., Nozaki T., Jishage K., Watanabe T., Sugimoto T., Nakagama H., Ochiya T., Sugimura T. Poly(ADP-ribose) polymerase gene disruption conferred mice resistant to streptozotocin-induced diabetes. Proc. Natl. Acad. Sci. USA. 96:1999;2301-2304.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 2301-2304
-
-
Masutani, M.1
Suzuki, H.2
Kamada, N.3
Watanabe, M.4
Ueda, O.5
Nozaki, T.6
Jishage, K.7
Watanabe, T.8
Sugimoto, T.9
Nakagama, H.10
Ochiya, T.11
Sugimura, T.12
-
71
-
-
0036263870
-
The crystal structure of the mouse apoptosis-inducing factor AIF
-
Mate M.J., Ortiz-Lombardia M., Boitel B., Haouz A., Tello D., Susin S.A., Penninger J., Kroemer G., Alzari P.M. The crystal structure of the mouse apoptosis-inducing factor AIF. Nat. Struct. Biol. 9:2002;442-446.
-
(2002)
Nat. Struct. Biol.
, vol.9
, pp. 442-446
-
-
Mate, M.J.1
Ortiz-Lombardia, M.2
Boitel, B.3
Haouz, A.4
Tello, D.5
Susin, S.A.6
Penninger, J.7
Kroemer, G.8
Alzari, P.M.9
-
72
-
-
0033575926
-
Procaspase-3 and poly(ADP)ribose polymerase (PARP) are calpain substrates
-
McGinnis K.M., Gnegy M.E., Park Y.H., Mukerjee N., Wang K.K. Procaspase-3 and poly(ADP)ribose polymerase (PARP) are calpain substrates. Biochem. Biophys. Res. Commun. 263:1999;94-99.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.263
, pp. 94-99
-
-
McGinnis, K.M.1
Gnegy, M.E.2
Park, Y.H.3
Mukerjee, N.4
Wang, K.K.5
-
73
-
-
0024456894
-
Zinc-binding domain of poly(ADP-ribose)polymerase participates in the recognition of single strand breaks on DNA
-
Menissier-de Murcia J., Molinete M., Gradwohl G., Simonin F., de Murcia G. Zinc-binding domain of poly(ADP-ribose)polymerase participates in the recognition of single strand breaks on DNA. J. Mol. Biol. 210:1989;229-233.
-
(1989)
J. Mol. Biol.
, vol.210
, pp. 229-233
-
-
Menissier-De Murcia, J.1
Molinete, M.2
Gradwohl, G.3
Simonin, F.4
De Murcia, G.5
-
74
-
-
0034868256
-
Poly(ADP-ribose) polymerase inhibitors attenuate necrotic but not apoptotic neuronal death in experimental models of cerebral ischemia
-
Moroni F., Meli E., Peruginelli F., Chiarugi A., Cozzi A., Picca R., Romagnoli P., Pellicciari R., Pellegrini-Giampietro D.E. Poly(ADP-ribose) polymerase inhibitors attenuate necrotic but not apoptotic neuronal death in experimental models of cerebral ischemia. Cell Death Differ. 8:2001;921-932.
-
(2001)
Cell Death Differ.
, vol.8
, pp. 921-932
-
-
Moroni, F.1
Meli, E.2
Peruginelli, F.3
Chiarugi, A.4
Cozzi, A.5
Picca, R.6
Romagnoli, P.7
Pellicciari, R.8
Pellegrini-Giampietro, D.E.9
-
75
-
-
0034068520
-
Activation of poly(ADP-ribose) polymerase in the rat hippocampus may contribute to cellular recovery following sublethal transient global ischemia
-
Nagayama T., Simon R.P., Chen D., Henshall D.C., Pei W., Stetler R.A., Chen J. Activation of poly(ADP-ribose) polymerase in the rat hippocampus may contribute to cellular recovery following sublethal transient global ischemia. J. Neurochem. 74:2000;1636-1645.
-
(2000)
J. Neurochem.
, vol.74
, pp. 1636-1645
-
-
Nagayama, T.1
Simon, R.P.2
Chen, D.3
Henshall, D.C.4
Pei, W.5
Stetler, R.A.6
Chen, J.7
-
76
-
-
0032437405
-
Intracellular ATP, a switch in the decision between apoptosis and necrosis
-
Nicotera P., Leist M., Ferrando-May E. Intracellular ATP, a switch in the decision between apoptosis and necrosis. Toxicol. Lett. 102-103:1998;139- 142.
-
(1998)
Toxicol. Lett.
, vol.102-103
, pp. 139-142
-
-
Nicotera, P.1
Leist, M.2
Ferrando-May, E.3
-
77
-
-
0037205746
-
A novel p53-inducible apoptogenic gene, PRG3, encodes a homologue of the apoptosis-inducing factor (AIF)
-
Ohiro Y., Garkavtsev I., Kobayashi S., Sreekumar K.R., Nantz R., Higashikubo B.T., Duffy S.L., Higashikubo R., Usheva A., Gius D., Kley N., Horikoshi N. A novel p53-inducible apoptogenic gene, PRG3, encodes a homologue of the apoptosis-inducing factor (AIF). FEBS Lett. 524:2002;163-171.
-
(2002)
FEBS Lett.
, vol.524
, pp. 163-171
-
-
Ohiro, Y.1
Garkavtsev, I.2
Kobayashi, S.3
Sreekumar, K.R.4
Nantz, R.5
Higashikubo, B.T.6
Duffy, S.L.7
Higashikubo, R.8
Usheva, A.9
Gius, D.10
Kley, N.11
Horikoshi, N.12
-
78
-
-
0032509239
-
Importance of poly(ADP-ribose) polymerase and its cleavage in apoptosis. Lesson from an uncleavable mutant
-
Oliver F.J., de la Rubia G., Rolli V., Ruiz-Ruiz M.C., de Murcia G., Murcia J.M. Importance of poly(ADP-ribose) polymerase and its cleavage in apoptosis. Lesson from an uncleavable mutant. J. Biol. Chem. 273:1998;33533-33539.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 33533-33539
-
-
Oliver, F.J.1
De La Rubia, G.2
Rolli, V.3
Ruiz-Ruiz, M.C.4
De Murcia, G.5
Murcia, J.M.6
-
79
-
-
0035421688
-
A role of the mitochondrial apoptosis-inducing factor in granulysin-induced apoptosis
-
Pardo J., Perez-Galan P., Gamen S., Marzo I., Monleon I., Kaspar A.A., Susin S.A., Kroemer G., Krensky A.M., Naval J., Anel A. A role of the mitochondrial apoptosis-inducing factor in granulysin-induced apoptosis. J. Immunol. 167:2001;1222-1229.
-
(2001)
J. Immunol.
, vol.167
, pp. 1222-1229
-
-
Pardo, J.1
Perez-Galan, P.2
Gamen, S.3
Marzo, I.4
Monleon, I.5
Kaspar, A.A.6
Susin, S.A.7
Kroemer, G.8
Krensky, A.M.9
Naval, J.10
Anel, A.11
-
80
-
-
0035811511
-
Mitochondrial endonuclease G is important for apoptosis in C. elegans
-
Parrish J., Li L., Klotz K., Ledwich D., Wang X., Xue D. Mitochondrial endonuclease G is important for apoptosis in C. elegans. Nature. 412:2001;90-94.
-
(2001)
Nature
, vol.412
, pp. 90-94
-
-
Parrish, J.1
Li, L.2
Klotz, K.3
Ledwich, D.4
Wang, X.5
Xue, D.6
-
81
-
-
0036799354
-
Role of caspases and apoptosis-inducing factor (AIF) in cladribine-induced apoptosis of B cell chronic lymphocytic leukemia
-
Perez-Galan P., Marzo I., Giraldo P., Rubio-Felix D., Lasierra P., Larrad L., Anel A., Naval J. Role of caspases and apoptosis-inducing factor (AIF) in cladribine-induced apoptosis of B cell chronic lymphocytic leukemia. Leukemia. 16:2002;2106-2114.
-
(2002)
Leukemia
, vol.16
, pp. 2106-2114
-
-
Perez-Galan, P.1
Marzo, I.2
Giraldo, P.3
Rubio-Felix, D.4
Lasierra, P.5
Larrad, L.6
Anel, A.7
Naval, J.8
-
82
-
-
0032981559
-
Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes
-
Pieper A.A., Brat D.J., Krug D.K., Watkins C.C., Gupta A., Blackshaw S., Verma A., Wang Z.Q., Snyder S.H. Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes. Proc. Natl. Acad. Sci. USA. 96:1999;3059-3064.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 3059-3064
-
-
Pieper, A.A.1
Brat, D.J.2
Krug, D.K.3
Watkins, C.C.4
Gupta, A.5
Blackshaw, S.6
Verma, A.7
Wang, Z.Q.8
Snyder, S.H.9
-
83
-
-
0034171108
-
Myocardial postischemic injury is reduced by polyADPripose polymerase-1 gene disruption
-
Pieper A.A., Walles T., Wei G., Clements E.E., Verma A., Snyder S.H., Zweier J.L. Myocardial postischemic injury is reduced by polyADPripose polymerase-1 gene disruption. Mol. Med. 6:2000;271-282.
-
(2000)
Mol. Med.
, vol.6
, pp. 271-282
-
-
Pieper, A.A.1
Walles, T.2
Wei, G.3
Clements, E.E.4
Verma, A.5
Snyder, S.H.6
Zweier, J.L.7
-
84
-
-
0034972410
-
In utero ethanol exposure causes mitochondrial dysfunction, which can result in apoptotic cell death in fetal brain: A potential role for 4-hydroxynonenal
-
Ramachandran V., Perez A., Chen J., Senthil D., Schenker S., Henderson G.I. In utero ethanol exposure causes mitochondrial dysfunction, which can result in apoptotic cell death in fetal brain a potential role for 4-hydroxynonenal . Alcohol Clin. Exp. Res. 25:2001;862-871.
-
(2001)
Alcohol Clin. Exp. Res.
, vol.25
, pp. 862-871
-
-
Ramachandran, V.1
Perez, A.2
Chen, J.3
Senthil, D.4
Schenker, S.5
Henderson, G.I.6
-
85
-
-
0035693680
-
Molecular mechanisms of glutamate receptor-mediated excitotoxic neuronal cell death
-
Sattler R., Tymianski M. Molecular mechanisms of glutamate receptor-mediated excitotoxic neuronal cell death. Mol. Neurobiol. 24:2001;107-129.
-
(2001)
Mol. Neurobiol.
, vol.24
, pp. 107-129
-
-
Sattler, R.1
Tymianski, M.2
-
86
-
-
0014183930
-
The use of nicotinamide to modify the toxicity of streptozotocin diabetes without loss of antitumor activity
-
Schein P.S., Cooney D.A., Vernon M.L. The use of nicotinamide to modify the toxicity of streptozotocin diabetes without loss of antitumor activity. Cancer Res. 27:1967;2324-2332.
-
(1967)
Cancer Res.
, vol.27
, pp. 2324-2332
-
-
Schein, P.S.1
Cooney, D.A.2
Vernon, M.L.3
-
87
-
-
0037151051
-
Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1
-
Schreiber V., Ame J.C., Dolle P., Schultz I., Rinaldi B., Fraulob V., Menissier-de Murcia J., de Murcia G. Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1. J. Biol. Chem. 277:2002;23028-23036.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 23028-23036
-
-
Schreiber, V.1
Ame, J.C.2
Dolle, P.3
Schultz, I.4
Rinaldi, B.5
Fraulob, V.6
Menissier-De Murcia, J.7
De Murcia, G.8
-
88
-
-
0038168188
-
Calpains mediate p53 activation and neuronal death evoked by DNA damage
-
Sedarous M., Keramaris E., O'Hare M., Melloni E., Slack R.S., Elce J.S., Greer P.A., Park D.S. Calpains mediate p53 activation and neuronal death evoked by DNA damage. J. Biol. Chem. 278:2003;26031-26038.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 26031-26038
-
-
Sedarous, M.1
Keramaris, E.2
O'Hare, M.3
Melloni, E.4
Slack, R.S.5
Elce, J.S.6
Greer, P.A.7
Park, D.S.8
-
89
-
-
0034733928
-
Poly(ADP-ribose) polymerase-1: What have we learned from the deficient mouse model
-
Shall S., de Murcia G. Poly(ADP-ribose) polymerase-1 what have we learned from the deficient mouse model . Mutat. Res. 460:2000;1-15.
-
(2000)
Mutat. Res.
, vol.460
, pp. 1-15
-
-
Shall, S.1
De Murcia, G.2
-
90
-
-
0035281786
-
The world according to PARP
-
Smith S. The world according to PARP. Trends Biochem. Sci. 26:2001;174-179.
-
(2001)
Trends Biochem. Sci.
, vol.26
, pp. 174-179
-
-
Smith, S.1
-
91
-
-
0034124881
-
Roles of poly(ADP-ribosyl)ation and PARP in apoptosis, DNA repair, genomic stability and functions of p53 and E2F-1
-
Smulson M.E., Simbulan-Rosenthal C.M., Boulares A.H., Yakovlev A., Stoica B., Iyer S., Luo R., Haddad B., Wang Z.Q., Pang T., Jung M., Dritschilo A., Rosenthal D.S. Roles of poly(ADP-ribosyl)ation and PARP in apoptosis, DNA repair, genomic stability and functions of p53 and E2F-1. Adv. Enzyme Regul. 40:2000;183-215.
-
(2000)
Adv. Enzyme Regul.
, vol.40
, pp. 183-215
-
-
Smulson, M.E.1
Simbulan-Rosenthal, C.M.2
Boulares, A.H.3
Yakovlev, A.4
Stoica, B.5
Iyer, S.6
Luo, R.7
Haddad, B.8
Wang, Z.Q.9
Pang, T.10
Jung, M.11
Dritschilo, A.12
Rosenthal, D.S.13
-
92
-
-
0033178444
-
Caspase-dependent and -independent death of camptothecin-treated embryonic cortical neurons
-
Stefanis L., Park D.S., Friedman W.J., Greene L.A. Caspase-dependent and -independent death of camptothecin-treated embryonic cortical neurons. J. Neurosci. 19:1999;6235-6247.
-
(1999)
J. Neurosci.
, vol.19
, pp. 6235-6247
-
-
Stefanis, L.1
Park, D.S.2
Friedman, W.J.3
Greene, L.A.4
-
93
-
-
0032150860
-
Glutamate-induced neuron death requires mitochondrial calcium uptake
-
Stout A.K., Raphael H.M., Kanterewicz B.I., Klann E., Reynolds I.J. Glutamate-induced neuron death requires mitochondrial calcium uptake. Nat. Neurosci. 1:1998;366-373.
-
(1998)
Nat. Neurosci.
, vol.1
, pp. 366-373
-
-
Stout, A.K.1
Raphael, H.M.2
Kanterewicz, B.I.3
Klann, E.4
Reynolds, I.J.5
-
94
-
-
0033521741
-
Molecular characterization of mitochondrial apoptosis-inducing factor
-
Susin S.A., Lorenzo H.K., Zamzami N., Marzo I., Snow B.E., Brothers G.M., Mangion J., Jacotot E., Costantini P., Loeffler M., Larochette N., Goodlett D.R., Aebersold R., Siderovski D.P., Penninger J.M., Kroemer G. Molecular characterization of mitochondrial apoptosis-inducing factor. Nature. 397:1999;441-446.
-
(1999)
Nature
, vol.397
, pp. 441-446
-
-
Susin, S.A.1
Lorenzo, H.K.2
Zamzami, N.3
Marzo, I.4
Snow, B.E.5
Brothers, G.M.6
Mangion, J.7
Jacotot, E.8
Costantini, P.9
Loeffler, M.10
Larochette, N.11
Goodlett, D.R.12
Aebersold, R.13
Siderovski, D.P.14
Penninger, J.M.15
Kroemer, G.16
-
95
-
-
0032127666
-
Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusion
-
Szabo C., Dawson V.L. Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusion. Trends Pharmacol. Sci. 19:1998;287-298.
-
(1998)
Trends Pharmacol. Sci.
, vol.19
, pp. 287-298
-
-
Szabo, C.1
Dawson, V.L.2
-
96
-
-
0032584164
-
Protection against peroxynitrite-induced fibroblast injury and arthritis development by inhibition of poly(ADP-ribose) synthase
-
Szabo C., Virag L., Cuzzocrea S., Scott G.S., Hake P., O'Connor M.P., Zingarelli B., Salzman A., Kun E. Protection against peroxynitrite-induced fibroblast injury and arthritis development by inhibition of poly(ADP-ribose) synthase. Proc. Natl. Acad. Sci. USA. 95:1998;3867-3872.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 3867-3872
-
-
Szabo, C.1
Virag, L.2
Cuzzocrea, S.3
Scott, G.S.4
Hake, P.5
O'Connor, M.P.6
Zingarelli, B.7
Salzman, A.8
Kun, E.9
-
97
-
-
0030862138
-
Neuroprotective effects of inhibiting poly(ADP-ribose) synthetase on focal cerebral ischemia in rats
-
Takahashi K., Greenberg J.H., Jackson P., Maclin K., Zhang J. Neuroprotective effects of inhibiting poly(ADP-ribose) synthetase on focal cerebral ischemia in rats. J. Cereb. Blood Flow Metab. 17:1997;1137-1142.
-
(1997)
J. Cereb. Blood Flow Metab.
, vol.17
, pp. 1137-1142
-
-
Takahashi, K.1
Greenberg, J.H.2
Jackson, P.3
MacLin, K.4
Zhang, J.5
-
98
-
-
0035202873
-
Regulation of microglial expression of integrins by poly(ADP-ribose) polymerase-1
-
Ullrich O., Diestel A., Eyupoglu I.Y., Nitsch R. Regulation of microglial expression of integrins by poly(ADP-ribose) polymerase-1. Nat. Cell Biol. 3:2001;1035-1042.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 1035-1042
-
-
Ullrich, O.1
Diestel, A.2
Eyupoglu, I.Y.3
Nitsch, R.4
-
99
-
-
0035674047
-
Endonuclease G: A mitochondrial protein released in apoptosis and involved in caspase-independent DNA degradation
-
van Loo G., Schotte P., van Gurp M., Demol H., Hoorelbeke B., Gevaert K., Rodriguez I., Ruiz-Carrillo A., Vandekerckhove J., Declercq W., Beyaert R., Vandenabeele P. Endonuclease G a mitochondrial protein released in apoptosis and involved in caspase-independent DNA degradation . Cell Death Differ. 8:2001;1136-1142.
-
(2001)
Cell Death Differ.
, vol.8
, pp. 1136-1142
-
-
Van Loo, G.1
Schotte, P.2
Van Gurp, M.3
Demol, H.4
Hoorelbeke, B.5
Gevaert, K.6
Rodriguez, I.7
Ruiz-Carrillo, A.8
Vandekerckhove, J.9
Declercq, W.10
Beyaert, R.11
Vandenabeele, P.12
-
100
-
-
0036733355
-
The therapeutic potential of poly(ADP-ribose) polymerase inhibitors
-
Virag L., Szabo C. The therapeutic potential of poly(ADP-ribose) polymerase inhibitors. Pharmacol. Rev. 54:2002;375-429.
-
(2002)
Pharmacol. Rev.
, vol.54
, pp. 375-429
-
-
Virag, L.1
Szabo, C.2
-
101
-
-
0037713529
-
Apoptosis inducing factor and PARP mediated injury in the MPTP mouse model of Parkinson's disease, in: Parkinson's Disease: The Life Cycle of the Dopamine Neuron Annals
-
Wang H., Shimoji M., Yu S.W., Dawson T.D., Dawson V.D. Apoptosis inducing factor and PARP mediated injury in the MPTP mouse model of Parkinson's disease, in: Parkinson's Disease: The Life Cycle of the Dopamine Neuron Annals. New York Academy of Science, New York. 991:2003;132-139.
-
(2003)
New York Academy of Science, New York
, vol.991
, pp. 132-139
-
-
Wang, H.1
Shimoji, M.2
Yu, S.W.3
Dawson, T.D.4
Dawson, V.D.5
-
102
-
-
0029841018
-
Measurement of nitric oxide and peroxynitrite generation in the postischemic heart. Evidence for peroxynitrite-mediated reperfusion injury
-
Wang P., Zweier J.L. Measurement of nitric oxide and peroxynitrite generation in the postischemic heart. Evidence for peroxynitrite-mediated reperfusion injury. J. Biol. Chem. 271:1996;29223-29230.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 29223-29230
-
-
Wang, P.1
Zweier, J.L.2
-
103
-
-
0037159784
-
Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans
-
Wang X., Yang C., Chai J., Shi Y., Xue D. Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans. Science. 298:2002;1587-1592.
-
(2002)
Science
, vol.298
, pp. 1587-1592
-
-
Wang, X.1
Yang, C.2
Chai, J.3
Shi, Y.4
Xue, D.5
-
104
-
-
0028922462
-
Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease
-
Wang Z.Q., Auer B., Stingl L., Berghammer H., Haidacher D., Schweiger M., Wagner E.F. Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease. Genes Dev. 9:1995;509-520.
-
(1995)
Genes Dev.
, vol.9
, pp. 509-520
-
-
Wang, Z.Q.1
Auer, B.2
Stingl, L.3
Berghammer, H.4
Haidacher, D.5
Schweiger, M.6
Wagner, E.F.7
-
105
-
-
17544364526
-
Reduction of cognitive and motor deficits after traumatic brain injury in mice deficient in poly(ADP-ribose) polymerase
-
Whalen M.J., Clark R.S., Dixon C.E., Robichaud P., Marion D.W., Vagni V., Graham S.H., Virag L., Hasko G., Stachlewitz R., Szabo C., Kochanek P.M. Reduction of cognitive and motor deficits after traumatic brain injury in mice deficient in poly(ADP-ribose) polymerase. J. Cereb. Blood Flow Metab. 19:1999;835-842.
-
(1999)
J. Cereb. Blood Flow Metab.
, vol.19
, pp. 835-842
-
-
Whalen, M.J.1
Clark, R.S.2
Dixon, C.E.3
Robichaud, P.4
Marion, D.W.5
Vagni, V.6
Graham, S.H.7
Virag, L.8
Hasko, G.9
Stachlewitz, R.10
Szabo, C.11
Kochanek, P.M.12
-
106
-
-
0029099358
-
Involvement of NAD-poly(ADP-ribose) metabolism in p53 regulation and its consequences
-
Whitacre C.M., Hashimoto H., Tsai M.L., Chatterjee S., Berger S.J., Berger N.A. Involvement of NAD-poly(ADP-ribose) metabolism in p53 regulation and its consequences. Cancer Res. 55:1995;3697-3701.
-
(1995)
Cancer Res.
, vol.55
, pp. 3697-3701
-
-
Whitacre, C.M.1
Hashimoto, H.2
Tsai, M.L.3
Chatterjee, S.4
Berger, S.J.5
Berger, N.A.6
-
107
-
-
0037067694
-
AMID, an apoptosis-inducing factor-homologous mitochondrion-associated protein, induces caspase-independent apoptosis
-
Wu M., Xu L.G., Li X., Zhai Z., Shu H.B. AMID, an apoptosis-inducing factor-homologous mitochondrion-associated protein, induces caspase-independent apoptosis. J. Biol. Chem. 277:2002;25617-25623.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 25617-25623
-
-
Wu, M.1
Xu, L.G.2
Li, X.3
Zhai, Z.4
Shu, H.B.5
-
109
-
-
0019812690
-
Streptozotocin and alloxan induce DNA strand breaks and poly(ADP-ribose) synthetase in pancreatic islets
-
Yamamoto H., Uchigata Y., Okamoto H. Streptozotocin and alloxan induce DNA strand breaks and poly(ADP-ribose) synthetase in pancreatic islets. Nature. 294:1981;284-286.
-
(1981)
Nature
, vol.294
, pp. 284-286
-
-
Yamamoto, H.1
Uchigata, Y.2
Okamoto, H.3
-
110
-
-
18544371050
-
DNA binding is required for the apoptogenic action of apoptosis inducing factor
-
Ye H., Cande C., Stephanou N.C., Jiang S., Gurbuxani S., Larochette N., Daugas E., Garrido C., Kroemer G., Wu H. DNA binding is required for the apoptogenic action of apoptosis inducing factor. Nat. Struct. Biol. 9:2002;680-684.
-
(2002)
Nat. Struct. Biol.
, vol.9
, pp. 680-684
-
-
Ye, H.1
Cande, C.2
Stephanou, N.C.3
Jiang, S.4
Gurbuxani, S.5
Larochette, N.6
Daugas, E.7
Garrido, C.8
Kroemer, G.9
Wu, H.10
-
111
-
-
0035834146
-
Poly(ADP-ribose) glycohydrolase mediates oxidative and excitotoxic neuronal death
-
Ying W., Sevigny M.B., Chen Y., Swanson R.A. Poly(ADP-ribose) glycohydrolase mediates oxidative and excitotoxic neuronal death. Proc. Natl. Acad. Sci. USA. 98:2001;12227-12232.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 12227-12232
-
-
Ying, W.1
Sevigny, M.B.2
Chen, Y.3
Swanson, R.A.4
-
112
-
-
0037067317
-
Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor
-
Yu S.W., Wang H., Poitras M.F., Coombs C., Bowers W.J., Federoff H.J., Poirier G.G., Dawson T.M., Dawson V.L. Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science. 297:2002;259-263.
-
(2002)
Science
, vol.297
, pp. 259-263
-
-
Yu, S.W.1
Wang, H.2
Poitras, M.F.3
Coombs, C.4
Bowers, W.J.5
Federoff, H.J.6
Poirier, G.G.7
Dawson, T.M.8
Dawson, V.L.9
-
113
-
-
0028294246
-
Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity
-
Zhang J., Dawson V.L., Dawson T.M., Snyder S.H. Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity. Science. 263:1994;687-689.
-
(1994)
Science
, vol.263
, pp. 687-689
-
-
Zhang, J.1
Dawson, V.L.2
Dawson, T.M.3
Snyder, S.H.4
-
114
-
-
20244364788
-
Intranuclear localization of apoptosis-inducing factor (AIF) and large scale DNA fragmentation after traumatic brain injury in rats and in neuronal cultures exposed to peroxynitrite
-
Zhang X., Chen J., Graham S.H., Du L., Kochanek P.M., Draviam R., Guo F., Nathaniel P.D., Szabo C., Watkins S.C., Clark R.S. Intranuclear localization of apoptosis-inducing factor (AIF) and large scale DNA fragmentation after traumatic brain injury in rats and in neuronal cultures exposed to peroxynitrite. J. Neurochem. 82:2002;181-191.
-
(2002)
J. Neurochem.
, vol.82
, pp. 181-191
-
-
Zhang, X.1
Chen, J.2
Graham, S.H.3
Du, L.4
Kochanek, P.M.5
Draviam, R.6
Guo, F.7
Nathaniel, P.D.8
Szabo, C.9
Watkins, S.C.10
Clark, R.S.11
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