The world according to PARP

Trends in Biochemical Sciences

Volumn 26, Issue 3, 2001, Pages 174-179

  Smith, Susan ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;

AMINO TERMINAL SEQUENCE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CELL TRANSPORT; CELLULAR DISTRIBUTION; CHROMOSOME REPLICATION; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME STRUCTURE; ENZYME SYNTHESIS; GENOTOXICITY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; REVIEW; SEQUENCE HOMOLOGY; TELOMERE;

AMINO ACID SEQUENCE; ANIMALS; CATALYSIS; MOLECULAR SEQUENCE DATA; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN PROCESSING, POST-TRANSLATIONAL; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0035281786     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0004(00)01780-1     Document Type: Review

References (48)

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10. + binding to poly(ADP-ribose) polymerase as derived from crystal structures and homology modeling
11. Structure of the catalytic fragment of poly(AD-ribose) polymerase from chicken
12. Common features of the NAD-binding and catalytic site of ADP-ribosylating toxins
13. Tankyrase, a poly(ADP-ribose) polymerase at human telomeres
14. Higher plants possess two structurally different poly(ADP-ribose) polymerases
15. PARP-2, a novel mammalian DNA damage-dependent poly(ADP-ribose) polymerase
16. pADPRT-2: A novel mammalian polymerizing (ADP-ribosyl)transferase gene related to truncated pADPRT homologues in plants and Caenorhabditis elegans
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18. Characterization of sPARP-1. An alternative product of PARP-1 gene with poly(ADP-ribose) polymerase activity independent of DNA strand breaks
19. The 193-kD vault protein, VPARP, is a novel poly(ADP-ribose) polymerase
20. Unlocking vaults: Organelles in search of a function
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26. Evidence that vault ribonucleoprotein particles localize to the nuclear pore complex
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29. Vaults are up-regulated in multidrug-resistant cancer cell lines
30. The Mr 193,000 vault protein is up-regulated in multidrug-resistant cancer cell lines
31. The telomerase reverse transcriptase: Components and regulation
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34. Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2
35. Telomeric localization of TRF2, a novel human telobox protein
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41. Tankyrase is a golgi-associated MAP kinase substrate that interacts with IRAP in GLUT4 vesicles
42. Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stability
43. Telomerase-associated protein TEP1 is not essential for telomerase activity or telomere length maintenance in vivo
44. Cell cycle dependent localization of the telomeric PARP, tankyrase, to nuclear pore complexes and centrosomes
45. Poly(ADP-ribose) polymerase at active centromeres and neocentromeres at metaphase
46. Isolation and characterization of the cDNA encoding bovine poly(ADP-ribose) glycohydrolase
47. Telomere shortening and apoptosis in telomerase-inhibited human tumor cells
48. Inhibition of telomerase limits the growth of human cancer cells