Poly(ADP-ribose) polymerase inhibitors attenuate necrotic but not apoptotic neuronal death in experimental models of cerebral ischemia

Cell Death and Differentiation

Volumn 8, Issue 9, 2001, Pages 921-932

  Moroni, F ^a   Meli, E ^a   Peruginelli, F ^a   Chiarugi, A ^a   Cozzi, A ^a   Picca, R ^a   Romagnoli, P ^a   Pellicciari, R ^b   Pellegrini Giampietro, D E ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF PERUGIA   (Italy)

Author keywords

Apoptosis; Necrosis; Neuroprotection; Oxygen glucose deprivation

Indexed keywords

3,4 DIHYDRO 5 [4 1[1 PIPERIDINYL]BUTHOXY] 1(2H) ISOQUINOLINONE; 6(5H) PHENANTHRIDINONE; BENZAMIDE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE INHIBITOR; ENZYME INHIBITOR; GLUCOSE; ISOCARBOSTYRIL DERIVATIVE; LACTATE DEHYDROGENASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; OXYGEN; PHENANTHRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; BIOCHEMISTRY; BRAIN CELL; BRAIN ISCHEMIA; BRAIN SLICE; CAROTID ARTERY OBSTRUCTION; CELL CULTURE; CELL DEATH; CELL LOSS; CELL ULTRASTRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; ELECTRON MICROSCOPY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME RELEASE; FLUORESCENCE; GERBIL; HIPPOCAMPUS; MORPHOLOGY; NERVE CELL; NERVE CELL LESION; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; TIME;

ANIMALS; APOPTOSIS; BENZAMIDES; BRAIN ISCHEMIA; CASPASE 3; CASPASES; CELL DEATH; CELL LINE; CEREBRAL CORTEX; ENZYME INHIBITORS; GERBILLINAE; ISOQUINOLINES; MICROSCOPY, ELECTRON; MICROSCOPY, FLUORESCENCE; NECROSIS; NEURONS; NEUROPROTECTIVE AGENTS; PHENANTHRENES; PIPERIDINES; POLY(ADP-RIBOSE) POLYMERASES; PYRAMIDAL CELLS; RATS; RATS, WISTAR;

EID: 0034868256     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400884     Document Type: Article

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