Molecular mechanisms of sulfasalazine-induced T-cell apoptosis

British Journal of Pharmacology

Volumn 137, Issue 5, 2002, Pages 608-620

  Liptay, Susanne ^a   Fulda, Simone ^a   Schanbacher, Marta ^a   Bourteele, Soizic ^a   Ferri, Karine F ^a   Kroemer, Guido ^a   Adler, Guido ^a   Debatin, Klaus M ^a   Schmid, Roland M ^a  

^a UNIVERSITY OF ULM   (Germany)

Author keywords

AIF; Bax; Caspase independent apoptosis; Chronic inflammatory diseases; Inflammatory bowel disease; Mitochondria; Rheumatoid arthritis; Sulfasalazine

Indexed keywords

APOPTOSIS INDUCING FACTOR; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE INHIBITOR; CYTOCHROME C; DNA FRAGMENT; NUCLEAR PROTEIN; PROTEIN BAX; PROTEIN BCL 2; SALAZOSULFAPYRIDINE;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL DEATH; CHRONIC INFLAMMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG MECHANISM; ENTERITIS; ENZYME ACTIVITY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; MOLECULAR MECHANICS; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SYNOVIOCYTE; T LYMPHOCYTE;

APOPTOSIS; APOPTOSIS INDUCING FACTOR; ENZYME ACTIVATION; FLAVOPROTEINS; GENES, BCL-2; HUMANS; JURKAT CELLS; MEMBRANE PROTEINS; SULFASALAZINE; T-LYMPHOCYTES;

EID: 0036850176     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704870     Document Type: Article

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