Biochemical and molecular basis of thimerosal-induced apoptosis in T cells: A major role of mitochondrial pathway

Genes and Immunity

Volumn 3, Issue 5, 2002, Pages 270-278

  Makani, S ^a   Gollapudi, S ^a   Yel, L ^a   Chiplunkar, S ^a   Gupta, S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Apoptosis inducing factor; Caspases; Cytochrome c; Glutathione; Mitochondria; Oxidative stress

Indexed keywords

APOPTOSIS INDUCING FACTOR; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; GLUTATHIONE; INHIBITOR OF APOPTOSIS PROTEIN; MERCURY; PROPIDIUM IODIDE; REACTIVE OXYGEN METABOLITE; THIOMERSAL; THIOSALICYLIC ACID; X LINKED INHIBITOR OF APOPTOSIS; BIRC4 PROTEIN, HUMAN; CASP3 PROTEIN, HUMAN; CASP9 PROTEIN, HUMAN; CASPASE; FLAVOPROTEIN; MEMBRANE PROTEIN; PDCD8 PROTEIN, HUMAN; PRESERVATIVE; PROTEIN; SALICYLIC ACID DERIVATIVE;

APOPTOSIS; ARTICLE; BIOCHEMISTRY; CELL PROTECTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG EXPOSURE; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME RELEASE; HUMAN; HUMAN CELL; INHIBITION KINETICS; LEUKEMIA CELL LINE; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; MOLECULAR MECHANICS; NICK END LABELING; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; UPREGULATION; VACCINATION; CELL MEMBRANE POTENTIAL; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; MITOCHONDRION; OXIDATIVE STRESS; PHYSIOLOGY;

APOPTOSIS; APOPTOSIS INDUCING FACTOR; CASPASE 3; CASPASE 9; CASPASES; CYTOCHROME C GROUP; ENZYME ACTIVATION; FLAVOPROTEINS; GLUTATHIONE; HUMANS; JURKAT CELLS; MEMBRANE POTENTIALS; MEMBRANE PROTEINS; MITOCHONDRIA; OXIDATIVE STRESS; PRESERVATIVES, PHARMACEUTICAL; PROTEINS; REACTIVE OXYGEN SPECIES; SALICYLIC ACIDS; T-LYMPHOCYTES; THIMEROSAL; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 0036689835     PISSN: 14664879     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gene.6363854     Document Type: Article

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