-
1
-
-
0034616165
-
Vav2 is an activator of Cdc42, Rac1, and RhoA
-
Abe K., Rossman K.L., Liu B., Ritola K.D., Chiang D., Campbell S.L., Burridge K., Der C.J. Vav2 is an activator of Cdc42, Rac1, and RhoA. J. Biol. Chem. 275:2000;10141-10149.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10141-10149
-
-
Abe, K.1
Rossman, K.L.2
Liu, B.3
Ritola, K.D.4
Chiang, D.5
Campbell, S.L.6
Burridge, K.7
Der, C.J.8
-
2
-
-
0037115521
-
GFP expression in the mammary gland for imaging of mammary tumor cells in transgenic mice
-
Ahmed F., Wyckoff J., Lin E.Y., Wang W., Wang Y., Hennighausen L., Miyazaki J., Jones J., Pollard J.W., Condeelis J.S., Segall J.E. GFP expression in the mammary gland for imaging of mammary tumor cells in transgenic mice. Cancer Res. 62:2002;7166-7169.
-
(2002)
Cancer Res.
, vol.62
, pp. 7166-7169
-
-
Ahmed, F.1
Wyckoff, J.2
Lin, E.Y.3
Wang, W.4
Wang, Y.5
Hennighausen, L.6
Miyazaki, J.7
Jones, J.8
Pollard, J.W.9
Condeelis, J.S.10
Segall, J.E.11
-
3
-
-
0033625871
-
Alphavbeta5 integrin recruits the CrkII-Dock180-rac1 complex for phagocytosis of apoptotic cells
-
Albert M.L., Kim J.I., Birge R.B. alphavbeta5 integrin recruits the CrkII-Dock180-rac1 complex for phagocytosis of apoptotic cells. Nat. Cell Biol. 2:2000;899-905.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 899-905
-
-
Albert, M.L.1
Kim, J.I.2
Birge, R.B.3
-
4
-
-
0035157971
-
Activation of Rhoa and ROCK are essential for detachment of migrating leukocytes
-
Alblas J., Ulfman L., Hordijk P., Koenderman L. Activation of Rhoa and ROCK are essential for detachment of migrating leukocytes. Mol. Biol. Cell. 12:2001;2137-2145.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 2137-2145
-
-
Alblas, J.1
Ulfman, L.2
Hordijk, P.3
Koenderman, L.4
-
5
-
-
0032565962
-
Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase
-
Arber S., Barbayannis F.A., Hanser H., Schneider C., Stanyon C.A., Bernard O., Caroni P. Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase. Nature. 393:1998;805-809.
-
(1998)
Nature
, vol.393
, pp. 805-809
-
-
Arber, S.1
Barbayannis, F.A.2
Hanser, H.3
Schneider, C.4
Stanyon, C.A.5
Bernard, O.6
Caroni, P.7
-
7
-
-
0036900955
-
ADF/cofilin and actin dynamics in disease. Acting-depolymerizing factor
-
Bamburg J.R., Wiggan O.P. ADF/cofilin and actin dynamics in disease. Acting-depolymerizing factor. Trends Cell Biol. 12:2002;598-605.
-
(2002)
Trends Cell Biol.
, vol.12
, pp. 598-605
-
-
Bamburg, J.R.1
Wiggan, O.P.2
-
8
-
-
0031443277
-
The Rho GTPase and a putative RhoGEF mediate a signaling pathway for the cell shape changes in Drosophila gastrulation
-
Barrett K., Leptin M., Settleman J. The Rho GTPase and a putative RhoGEF mediate a signaling pathway for the cell shape changes in Drosophila gastrulation. Cell. 91:1997;905-915.
-
(1997)
Cell
, vol.91
, pp. 905-915
-
-
Barrett, K.1
Leptin, M.2
Settleman, J.3
-
9
-
-
0033531955
-
Characterization of rac and cdc42 activation in chemoattractant- stimulated human neutrophils using a novel assay for active GTPases
-
Benard V., Bohl B.P., Bokoch G.M. Characterization of rac and cdc42 activation in chemoattractant-stimulated human neutrophils using a novel assay for active GTPases. J. Biol. Chem. 274:1999;13198-13204.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 13198-13204
-
-
Benard, V.1
Bohl, B.P.2
Bokoch, G.M.3
-
10
-
-
0036270763
-
The subcellular destinations of APC proteins
-
Bienz M. The subcellular destinations of APC proteins. Nat. Rev., Mol. Cell Biol. 3:2002;328-338.
-
(2002)
Nat. Rev., Mol. Cell Biol.
, vol.3
, pp. 328-338
-
-
Bienz, M.1
-
11
-
-
0034213327
-
Rho GTPases and their effector proteins
-
Bishop A.L., Hall A. Rho GTPases and their effector proteins. Biochem. J. 348:2000;241-255.
-
(2000)
Biochem. J.
, vol.348
, pp. 241-255
-
-
Bishop, A.L.1
Hall, A.2
-
12
-
-
0034687235
-
Interactions of ADF/cofilin, Arp2/3 complex, capping protein and profilin in remodeling of branched actin filament networks
-
Blanchoin L., Pollard T.D., Mullins R.D. Interactions of ADF/cofilin, Arp2/3 complex, capping protein and profilin in remodeling of branched actin filament networks. Curr. Biol. 10:2000;1273-1282.
-
(2000)
Curr. Biol.
, vol.10
, pp. 1273-1282
-
-
Blanchoin, L.1
Pollard, T.D.2
Mullins, R.D.3
-
13
-
-
0029870402
-
Rac GTPase interacts specifically with phosphatidylinositol 3-kinase
-
Bokoch G.M., Vlahos C.J., Wang Y., Knaus U.G., Traynor-Kaplan A.E. Rac GTPase interacts specifically with phosphatidylinositol 3-kinase. Biochem. J. 315:1996;775-779.
-
(1996)
Biochem. J.
, vol.315
, pp. 775-779
-
-
Bokoch, G.M.1
Vlahos, C.J.2
Wang, Y.3
Knaus, U.G.4
Traynor-Kaplan, A.E.5
-
14
-
-
0036045768
-
Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex
-
Brugnera E., Haney L., Grimsley C., Lu M., Walk S.F., Tosello-Trampont A.C., Macara I.G., Madhani H., Fink G.R., Ravichandran K.S. Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex. Nat. Cell Biol. 4:2002;574-582.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 574-582
-
-
Brugnera, E.1
Haney, L.2
Grimsley, C.3
Lu, M.4
Walk, S.F.5
Tosello-Trampont, A.C.6
MacAra, I.G.7
Madhani, H.8
Fink, G.R.9
Ravichandran, K.S.10
-
15
-
-
0036015163
-
The Nck family of adapter proteins: Regulators of actin cytoskeleton
-
Buday L., Wunderlich L., Tamas P. The Nck family of adapter proteins: regulators of actin cytoskeleton. Cell Signalling. 14:2002;723-731.
-
(2002)
Cell Signalling
, vol.14
, pp. 723-731
-
-
Buday, L.1
Wunderlich, L.2
Tamas, P.3
-
16
-
-
0028053435
-
Diaphanous is required for cytokinesis in Drosophila and shares domains of similarity with the products of the limb deformity gene
-
Castrillon D.H., Wasserman S.A. Diaphanous is required for cytokinesis in Drosophila and shares domains of similarity with the products of the limb deformity gene. Development. 120:1994;3367-3377.
-
(1994)
Development
, vol.120
, pp. 3367-3377
-
-
Castrillon, D.H.1
Wasserman, S.A.2
-
17
-
-
0032825266
-
Regulation of cell contraction and membrane ruffling by distinct signals in migratory cells
-
Cheresh D.A., Leng J., Klemke R.L. Regulation of cell contraction and membrane ruffling by distinct signals in migratory cells. J. Cell Biol. 146:1999;1107-1116.
-
(1999)
J. Cell Biol.
, vol.146
, pp. 1107-1116
-
-
Cheresh, D.A.1
Leng, J.2
Klemke, R.L.3
-
18
-
-
0037115488
-
Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity
-
Cote J.F., Vuori K. Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity. J. Cell Sci. 115:2002;4901-4913.
-
(2002)
J. Cell Sci.
, vol.115
, pp. 4901-4913
-
-
Cote, J.F.1
Vuori, K.2
-
19
-
-
0035910554
-
Rac/Cdc42 and p65PAK regulate the microtubule-destabilizing protein stathmin through phosphorylation at serine 16
-
Daub H., Gevaert K., Vandekerckhove J., Sobel A., Hall A. Rac/Cdc42 and p65PAK regulate the microtubule-destabilizing protein stathmin through phosphorylation at serine 16. J. Biol. Chem. 276:2001;1677-1680.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 1677-1680
-
-
Daub, H.1
Gevaert, K.2
Vandekerckhove, J.3
Sobel, A.4
Hall, A.5
-
20
-
-
0035808558
-
Guidance of cell migration by EGF receptor signaling during Drosophila oogenesis
-
Duchek P., Rorth P. Guidance of cell migration by EGF receptor signaling during Drosophila oogenesis. Science. 291:2001;131-133.
-
(2001)
Science
, vol.291
, pp. 131-133
-
-
Duchek, P.1
Rorth, P.2
-
21
-
-
0035812719
-
Guidance of cell migration by the Drosophila PDGF/VEGF receptor
-
Duchek P., Somogyi K., Jekely G., Beccari S., Rorth P. Guidance of cell migration by the Drosophila PDGF/VEGF receptor. Cell. 107:2001;17-26.
-
(2001)
Cell
, vol.107
, pp. 17-26
-
-
Duchek, P.1
Somogyi, K.2
Jekely, G.3
Beccari, S.4
Rorth, P.5
-
22
-
-
0037102301
-
Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck
-
Eden S., Rohatgi R., Podtelejnikov A.V., Mann M., Kirschner M.W. Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck. Nature. 418:2002;790-793.
-
(2002)
Nature
, vol.418
, pp. 790-793
-
-
Eden, S.1
Rohatgi, R.2
Podtelejnikov, A.V.3
Mann, M.4
Kirschner, M.W.5
-
23
-
-
0033194037
-
Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics
-
Edwards D.C., Sanders L.C., Bokoch G.M., Gill G.N. Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics. Nat. Cell Biol. 1:1999;253-259.
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 253-259
-
-
Edwards, D.C.1
Sanders, L.C.2
Bokoch, G.M.3
Gill, G.N.4
-
24
-
-
0026051936
-
Genes required for the engulfment of cell corpses during programmed cell death in Caenorhabditis elegans
-
Ellis R.E., Jacobson D.M., Horvitz H.R. Genes required for the engulfment of cell corpses during programmed cell death in Caenorhabditis elegans. Genetics. 129:1991;79-94.
-
(1991)
Genetics
, vol.129
, pp. 79-94
-
-
Ellis, R.E.1
Jacobson, D.M.2
Horvitz, H.R.3
-
25
-
-
0035943401
-
Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta
-
Etienne-Manneville S., Hall A. Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta. Cell. 106:2001;489-498.
-
(2001)
Cell
, vol.106
, pp. 489-498
-
-
Etienne-Manneville, S.1
Hall, A.2
-
26
-
-
0037069690
-
Rho GTPases in cell biology
-
Etienne-Manneville S., Hall A. Rho GTPases in cell biology. Nature. 420:2002;629-635.
-
(2002)
Nature
, vol.420
, pp. 629-635
-
-
Etienne-Manneville, S.1
Hall, A.2
-
27
-
-
0037434790
-
Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity
-
Etienne-Manneville S., Hall A. Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity. Nature. 421:2003;753-756.
-
(2003)
Nature
, vol.421
, pp. 753-756
-
-
Etienne-Manneville, S.1
Hall, A.2
-
28
-
-
17944375813
-
Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration
-
Fukui Y., Hashimoto O., Sanui T., Oono T., Koga H., Abe M., Inayoshi A., Noda M., Oike M., Shirai T., Sasazuki T. Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration. Nature. 412:2001;826-831.
-
(2001)
Nature
, vol.412
, pp. 826-831
-
-
Fukui, Y.1
Hashimoto, O.2
Sanui, T.3
Oono, T.4
Koga, H.5
Abe, M.6
Inayoshi, A.7
Noda, M.8
Oike, M.9
Shirai, T.10
Sasazuki, T.11
-
29
-
-
0037205265
-
Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis
-
Funamoto S., Meili R., Lee S., Parry L., Firtel R.A. Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis. Cell. 109:2002;611-623.
-
(2002)
Cell
, vol.109
, pp. 611-623
-
-
Funamoto, S.1
Meili, R.2
Lee, S.3
Parry, L.4
Firtel, R.A.5
-
30
-
-
0033912699
-
The T-cell receptor regulates Akt (protein kinase B) via a pathway involving Rac1 and phosphatidylinositide 3-kinase
-
Genot E.M., Arrieumerlou C., Ku G., Burgering B.M., Weiss A., Kramer I.M. The T-cell receptor regulates Akt (protein kinase B) via a pathway involving Rac1 and phosphatidylinositide 3-kinase. Mol. Cell. Biol. 20:2000;5469-5478.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 5469-5478
-
-
Genot, E.M.1
Arrieumerlou, C.2
Ku, G.3
Burgering, B.M.4
Weiss, A.5
Kramer, I.M.6
-
31
-
-
0036606515
-
Axon guidance: Receptor complexes and signaling mechanisms
-
Grunwald I.C., Klein R. Axon guidance: receptor complexes and signaling mechanisms. Curr. Opin. Neurobiol. 12:2002;250-259.
-
(2002)
Curr. Opin. Neurobiol.
, vol.12
, pp. 250-259
-
-
Grunwald, I.C.1
Klein, R.2
-
32
-
-
17944376439
-
CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration
-
Gumienny T.L., Brugnera E., Tosello-Trampont A.C., Kinchen J.M., Haney L.B., Nishiwaki K., Walk S.F., Nemergut M.E., Macara I.G., Francis R., Schedl T., Qin Y., Van Aelst L., Hengartner M.O., Ravichandran K.S. CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration. Cell. 107:2001;27-41.
-
(2001)
Cell
, vol.107
, pp. 27-41
-
-
Gumienny, T.L.1
Brugnera, E.2
Tosello-Trampont, A.C.3
Kinchen, J.M.4
Haney, L.B.5
Nishiwaki, K.6
Walk, S.F.7
Nemergut, M.E.8
MacAra, I.G.9
Francis, R.10
Schedl, T.11
Qin, Y.12
Van Aelst, L.13
Hengartner, M.O.14
Ravichandran, K.S.15
-
33
-
-
0036273491
-
Evolutionary conservation of microtubule-capture mechanisms
-
Gundersen G.G. Evolutionary conservation of microtubule-capture mechanisms. Nat. Rev., Mol. Cell Biol. 3:2002;296-304.
-
(2002)
Nat. Rev., Mol. Cell Biol.
, vol.3
, pp. 296-304
-
-
Gundersen, G.G.1
-
34
-
-
15144353776
-
Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav
-
Han J., Luby-Phelps K., Das B., Shu X., Xia Y., Mosteller R.D., Krishna U.M., Falck J.R., White M.A., Broek D. Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav. Science. 279:1998;558-560.
-
(1998)
Science
, vol.279
, pp. 558-560
-
-
Han, J.1
Luby-Phelps, K.2
Das, B.3
Shu, X.4
Xia, Y.5
Mosteller, R.D.6
Krishna, U.M.7
Falck, J.R.8
White, M.A.9
Broek, D.10
-
35
-
-
0029926307
-
DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane
-
Hasegawa H., Kiyokawa E., Tanaka S., Nagashima K., Gotoh N., Shibuya M., Kurata T., Matsuda M. DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane. Mol. Cell. Biol. 16:1996;1770-1776.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 1770-1776
-
-
Hasegawa, H.1
Kiyokawa, E.2
Tanaka, S.3
Nagashima, K.4
Gotoh, N.5
Shibuya, M.6
Kurata, T.7
Matsuda, M.8
-
36
-
-
0034638836
-
Spatial sensing in fibroblasts mediated by 3′ phosphoinositides
-
Haugh J.M., Codazzi F., Teruel M., Meyer T. Spatial sensing in fibroblasts mediated by 3′ phosphoinositides. J. Cell Biol. 151:2000;1269-1280.
-
(2000)
J. Cell Biol.
, vol.151
, pp. 1269-1280
-
-
Haugh, J.M.1
Codazzi, F.2
Teruel, M.3
Meyer, T.4
-
37
-
-
0029278739
-
PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase
-
Hawkins P.T., Eguinoa A., Qiu R.G., Stokoe D., Cooke F.T., Walters R., Wennstrom S., Claesson-Welsh L., Evans T., Symons M.et al. PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase. Curr. Biol. 5:1995;393-403.
-
(1995)
Curr. Biol.
, vol.5
, pp. 393-403
-
-
Hawkins, P.T.1
Eguinoa, A.2
Qiu, R.G.3
Stokoe, D.4
Cooke, F.T.5
Walters, R.6
Wennstrom, S.7
Claesson-Welsh, L.8
Evans, T.9
Symons, M.10
-
38
-
-
0034635452
-
Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation
-
Hirsch E., Katanaev V.L., Garlanda C., Azzolino O., Pirola L., Silengo L., Sozzani S., Mantovani A., Altruda F., Wymann M.P. Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation. Science. 287:2000;1049-1053.
-
(2000)
Science
, vol.287
, pp. 1049-1053
-
-
Hirsch, E.1
Katanaev, V.L.2
Garlanda, C.3
Azzolino, O.4
Pirola, L.5
Silengo, L.6
Sozzani, S.7
Mantovani, A.8
Altruda, F.9
Wymann, M.P.10
-
39
-
-
0037205230
-
Tumor suppressor PTEN mediates sensing of chemoattractant gradients
-
Iijima M., Devreotes P. Tumor suppressor PTEN mediates sensing of chemoattractant gradients. Cell. 109:2002;599-610.
-
(2002)
Cell
, vol.109
, pp. 599-610
-
-
Iijima, M.1
Devreotes, P.2
-
40
-
-
0035141074
-
Coordination of microtubules and the actin cytoskeleton by the Rho effector mDia1
-
Ishizaki T., Morishima Y., Okamoto M., Furuyashiki T., Kato T., Narumiya S. Coordination of microtubules and the actin cytoskeleton by the Rho effector mDia1. Nat. Cell Biol. 3:2001;8-14.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 8-14
-
-
Ishizaki, T.1
Morishima, Y.2
Okamoto, M.3
Furuyashiki, T.4
Kato, T.5
Narumiya, S.6
-
41
-
-
0036063057
-
Dynamic analysis of dorsal closure in Drosophila: From genetics to cell biology
-
Jacinto A., Woolner S., Martin P. Dynamic analysis of dorsal closure in Drosophila: from genetics to cell biology. Dev. Cell. 3:2002;9-19.
-
(2002)
Dev. Cell
, vol.3
, pp. 9-19
-
-
Jacinto, A.1
Woolner, S.2
Martin, P.3
-
42
-
-
0036226855
-
Identification of a link between the tumour suppressor APC and the kinesin superfamily
-
Jimbo T., Kawasaki Y., Koyama R., Sato R., Takada S., Haraguchi K., Akiyama T. Identification of a link between the tumour suppressor APC and the kinesin superfamily. Nat. Cell Biol. 4:2002;323-327.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 323-327
-
-
Jimbo, T.1
Kawasaki, Y.2
Koyama, R.3
Sato, R.4
Takada, S.5
Haraguchi, K.6
Akiyama, T.7
-
43
-
-
0033615977
-
Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo
-
Kawano Y., Fukata Y., Oshiro N., Amano M., Nakamura T., Ito M., Matsumura F., Inagaki M., Kaibuchi K. Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo. J. Cell Biol. 147:1999;1023-1038.
-
(1999)
J. Cell Biol.
, vol.147
, pp. 1023-1038
-
-
Kawano, Y.1
Fukata, Y.2
Oshiro, N.3
Amano, M.4
Nakamura, T.5
Ito, M.6
Matsumura, F.7
Inagaki, M.8
Kaibuchi, K.9
-
44
-
-
0034682888
-
Asef, a link between the tumor suppressor APC and G-protein signaling
-
Kawasaki Y., Senda T., Ishidate T., Koyama R., Morishita T., Iwayama Y., Higuchi O., Akiyama T. Asef, a link between the tumor suppressor APC and G-protein signaling. Science. 289:2000;1194-1197.
-
(2000)
Science
, vol.289
, pp. 1194-1197
-
-
Kawasaki, Y.1
Senda, T.2
Ishidate, T.3
Koyama, R.4
Morishita, T.5
Iwayama, Y.6
Higuchi, O.7
Akiyama, T.8
-
45
-
-
0033571033
-
A role for p21-activated kinase in endothelial cell migration
-
Kiosses W.B., Daniels R.H., Otey C., Bokoch G.M., Schwartz M.A. A role for p21-activated kinase in endothelial cell migration. J. Cell Biol. 147:1999;831-844.
-
(1999)
J. Cell Biol.
, vol.147
, pp. 831-844
-
-
Kiosses, W.B.1
Daniels, R.H.2
Otey, C.3
Bokoch, G.M.4
Schwartz, M.A.5
-
46
-
-
0032213110
-
Activation of Rac1 by a Crk SH3-binding protein, DOCK180
-
Kiyokawa E., Hashimoto Y., Kobayashi S., Sugimura H., Kurata T., Matsuda M. Activation of Rac1 by a Crk SH3-binding protein, DOCK180. Genes Dev. 12:1998;3331-3336.
-
(1998)
Genes Dev.
, vol.12
, pp. 3331-3336
-
-
Kiyokawa, E.1
Hashimoto, Y.2
Kobayashi, S.3
Sugimura, H.4
Kurata, T.5
Matsuda, M.6
-
47
-
-
0032559562
-
CAS/Crk coupling serves as a "molecular switch" for induction of cell migration
-
Klemke R.L., Leng J., Molander R., Brooks P.C., Vuori K., Cheresh D.A. CAS/Crk coupling serves as a "molecular switch" for induction of cell migration. J. Cell Biol. 140:1998;961-972.
-
(1998)
J. Cell Biol.
, vol.140
, pp. 961-972
-
-
Klemke, R.L.1
Leng, J.2
Molander, R.3
Brooks, P.C.4
Vuori, K.5
Cheresh, D.A.6
-
48
-
-
0034747401
-
Beta1PIX, the PAK-interacting exchange factor, requires localization via a coiled-coil region to promote microvillus-like structures and membrane ruffles
-
Koh C.G., Manser E., Zhao Z.S., Ng C.P., Lim L. Beta1PIX, the PAK-interacting exchange factor, requires localization via a coiled-coil region to promote microvillus-like structures and membrane ruffles. J. Cell Sci. 114:2001;4239-4251.
-
(2001)
J. Cell Sci.
, vol.114
, pp. 4239-4251
-
-
Koh, C.G.1
Manser, E.2
Zhao, Z.S.3
Ng, C.P.4
Lim, L.5
-
49
-
-
0034644603
-
Localized Rac activation dynamics visualized in living cells
-
Kraynov V.S., Chamberlain C., Bokoch G.M., Schwartz M.A., Slabaugh S., Hahn K.M. Localized Rac activation dynamics visualized in living cells. Science. 290:2000;333-337.
-
(2000)
Science
, vol.290
, pp. 333-337
-
-
Kraynov, V.S.1
Chamberlain, C.2
Bokoch, G.M.3
Schwartz, M.A.4
Slabaugh, S.5
Hahn, K.M.6
-
50
-
-
0035155824
-
Stathmin/Op18 phosphorylation is regulated by microtubule assembly
-
Kuntziger T., Gavet O., Manceau V., Sobel A., Bornens M. Stathmin/Op18 phosphorylation is regulated by microtubule assembly. Mol. Biol. Cell. 12:2001;437-448.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 437-448
-
-
Kuntziger, T.1
Gavet, O.2
Manceau, V.3
Sobel, A.4
Bornens, M.5
-
51
-
-
0035427387
-
Cell migration in invertebrates: Clues from border and distal tip cells
-
Lehmann R. Cell migration in invertebrates: clues from border and distal tip cells. Curr. Opin. Genet. Dev. 11:2001;457-463.
-
(2001)
Curr. Opin. Genet. Dev.
, vol.11
, pp. 457-463
-
-
Lehmann, R.1
-
52
-
-
0034635221
-
Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction
-
Li Z., Jiang H., Xie W., Zhang Z., Smrcka A.V., Wu D. Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction. Science. 287:2000;1046-1049.
-
(2000)
Science
, vol.287
, pp. 1046-1049
-
-
Li, Z.1
Jiang, H.2
Xie, W.3
Zhang, Z.4
Smrcka, A.V.5
Wu, D.6
-
53
-
-
0033826334
-
Vav2 activates Rac1, Cdc42, and RhoA downstream from growth factor receptors but not beta1 integrins
-
Liu B.P., Burridge K. Vav2 activates Rac1, Cdc42, and RhoA downstream from growth factor receptors but not beta1 integrins. Mol. Cell. Biol. 20:2000;7160-7169.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 7160-7169
-
-
Liu, B.P.1
Burridge, K.2
-
54
-
-
0032454273
-
Microtubule depolymerization induces stress fibers, focal adhesions, and DNA synthesis via the GTP-binding protein Rho
-
Liu B.P., Chrzanowska-Wodnicka M., Burridge K. Microtubule depolymerization induces stress fibers, focal adhesions, and DNA synthesis via the GTP-binding protein Rho. Cell Adhes. Commun. 5:1998;249-255.
-
(1998)
Cell Adhes. Commun.
, vol.5
, pp. 249-255
-
-
Liu, B.P.1
Chrzanowska-Wodnicka, M.2
Burridge, K.3
-
55
-
-
0036538577
-
Cytoplasmic dynein-associated structures move bidirectionally in vivo
-
Ma S., Chisholm R.L. Cytoplasmic dynein-associated structures move bidirectionally in vivo. J. Cell Sci. 115:2002;1453-1460.
-
(2002)
J. Cell Sci.
, vol.115
, pp. 1453-1460
-
-
Ma, S.1
Chisholm, R.L.2
-
56
-
-
0033529620
-
Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase
-
Maekawa M., Ishizaki T., Boku S., Watanabe N., Fujita A., Iwamatsu A., Obinata T., Ohashi K., Mizuno K., Narumiya S. Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase. Science. 285:1999;895-898.
-
(1999)
Science
, vol.285
, pp. 895-898
-
-
Maekawa, M.1
Ishizaki, T.2
Boku, S.3
Watanabe, N.4
Fujita, A.5
Iwamatsu, A.6
Obinata, T.7
Ohashi, K.8
Mizuno, K.9
Narumiya, S.10
-
57
-
-
0033398527
-
Mutations in the Rho1 small GTPase disrupt morphogenesis and segmentation during early Drosophila development
-
Magie C.R., Meyer M.R., Gorsuch M.S., Parkhurst S.M. Mutations in the Rho1 small GTPase disrupt morphogenesis and segmentation during early Drosophila development. Development. 126:1999;5353-5364.
-
(1999)
Development
, vol.126
, pp. 5353-5364
-
-
Magie, C.R.1
Meyer, M.R.2
Gorsuch, M.S.3
Parkhurst, S.M.4
-
58
-
-
0036537895
-
GIT1 functions in a motile, multi-molecular signaling complex that regulates protrusive activity and cell migration
-
Manabe Ri R., Kovalenko M., Webb D.J., Horwitz A.R. GIT1 functions in a motile, multi-molecular signaling complex that regulates protrusive activity and cell migration. J. Cell Sci. 115:2002;1497-1510.
-
(2002)
J. Cell Sci.
, vol.115
, pp. 1497-1510
-
-
Manabe Ri, R.1
Kovalenko, M.2
Webb, D.J.3
Horwitz, A.R.4
-
59
-
-
0031610579
-
PAK kinases are directly coupled to the PIX family of nucleotide exchange factors
-
Manser E., Loo T.H., Koh C.G., Zhao Z.S., Chen X.Q., Tan L., Tan I., Leung T., Lim L. PAK kinases are directly coupled to the PIX family of nucleotide exchange factors. Mol. Cell. 1:1998;183-192.
-
(1998)
Mol. Cell
, vol.1
, pp. 183-192
-
-
Manser, E.1
Loo, T.H.2
Koh, C.G.3
Zhao, Z.S.4
Chen, X.Q.5
Tan, L.6
Tan, I.7
Leung, T.8
Lim, L.9
-
60
-
-
0036713381
-
Zizimin1, a novel Cdc42 activator, reveals a new GEF domain for Rho proteins
-
Meller N., Irani-Tehrani M., Kiosses W.B., Del Pozo M.A., Schwartz M.A. Zizimin1, a novel Cdc42 activator, reveals a new GEF domain for Rho proteins. Nat. Cell Biol. 4:2002;639-647.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 639-647
-
-
Meller, N.1
Irani-Tehrani, M.2
Kiosses, W.B.3
Del Pozo, M.A.4
Schwartz, M.A.5
-
61
-
-
0036828324
-
Signaling mechanisms that regulate actin-based motility processes in the nervous system
-
Meyer G., Feldman E.L. Signaling mechanisms that regulate actin-based motility processes in the nervous system. J. Neurochem. 83:2002;490-503.
-
(2002)
J. Neurochem.
, vol.83
, pp. 490-503
-
-
Meyer, G.1
Feldman, E.L.2
-
62
-
-
0030931216
-
Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation
-
Michiels F., Stam J.C., Hordijk P.L., van der Kammen R.A., Ruuls-Van Stalle L., Feltkamp C.A., Collard J.G. Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation. J. Cell Biol. 137:1997;387-398.
-
(1997)
J. Cell Biol.
, vol.137
, pp. 387-398
-
-
Michiels, F.1
Stam, J.C.2
Hordijk, P.L.3
Van Der Kammen, R.A.4
Ruuls-Van Stalle, L.5
Feltkamp, C.A.6
Collard, J.G.7
-
63
-
-
0030049170
-
Actin-based cell motility and cell locomotion
-
Mitchison T.J., Cramer L.P. Actin-based cell motility and cell locomotion. Cell. 84:1996;371-379.
-
(1996)
Cell
, vol.84
, pp. 371-379
-
-
Mitchison, T.J.1
Cramer, L.P.2
-
64
-
-
0037213689
-
Rho GTPase-activating proteins in cell regulation
-
Moon S.Y., Zheng Y. Rho GTPase-activating proteins in cell regulation. Trends Cell Biol. 13:2003;13-22.
-
(2003)
Trends Cell Biol.
, vol.13
, pp. 13-22
-
-
Moon, S.Y.1
Zheng, Y.2
-
65
-
-
0035838422
-
Critical role for the EB1 and APC interaction in the regulation of microtubule polymerization
-
Nakamura M., Zhou X.Z., Lu K.P. Critical role for the EB1 and APC interaction in the regulation of microtubule polymerization. Curr. Biol. 11:2001;1062-1067.
-
(2001)
Curr. Biol.
, vol.11
, pp. 1062-1067
-
-
Nakamura, M.1
Zhou, X.Z.2
Lu, K.P.3
-
66
-
-
0036893185
-
DOCK2 associates with CrkL and regulates Rac1 in human leukemia cell lines
-
Nishihara H., Maeda M., Oda A., Tsuda M., Sawa H., Nagashima K., Tanaka S. DOCK2 associates with CrkL and regulates Rac1 in human leukemia cell lines. Blood. 100:2002;3968-3974.
-
(2002)
Blood
, vol.100
, pp. 3968-3974
-
-
Nishihara, H.1
Maeda, M.2
Oda, A.3
Tsuda, M.4
Sawa, H.5
Nagashima, K.6
Tanaka, S.7
-
67
-
-
0028961293
-
Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
-
Nobes C.D., Hall A. Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell. 81:1995;53-62.
-
(1995)
Cell
, vol.81
, pp. 53-62
-
-
Nobes, C.D.1
Hall, A.2
-
68
-
-
0033594123
-
Rho GTPases control polarity, protrusion, and adhesion during cell movement
-
Nobes C.D., Hall A. Rho GTPases control polarity, protrusion, and adhesion during cell movement. J. Cell Biol. 144:1999;1235-1244.
-
(1999)
J. Cell Biol.
, vol.144
, pp. 1235-1244
-
-
Nobes, C.D.1
Hall, A.2
-
69
-
-
0028837170
-
Activation of the small GTP-binding proteins rho and rac by growth factor receptors
-
Nobes C.D., Hawkins P., Stephens L., Hall A. Activation of the small GTP-binding proteins rho and rac by growth factor receptors. J. Cell Sci. 108:1995;225-233.
-
(1995)
J. Cell Sci.
, vol.108
, pp. 225-233
-
-
Nobes, C.D.1
Hawkins, P.2
Stephens, L.3
Hall, A.4
-
70
-
-
0032479975
-
PAK promotes morphological changes by acting upstream of Rac
-
Obermeier A., Ahmed S., Manser E., Yen S.C., Hall C., Lim L. PAK promotes morphological changes by acting upstream of Rac. EMBO J. 17:1998;4328-4339.
-
(1998)
EMBO J.
, vol.17
, pp. 4328-4339
-
-
Obermeier, A.1
Ahmed, S.2
Manser, E.3
Yen, S.C.4
Hall, C.5
Lim, L.6
-
71
-
-
0034907213
-
MDia mediates Rho-regulated formation and orientation of stable microtubules
-
Palazzo A.F., Cook T.A., Alberts A.S., Gundersen G.G. mDia mediates Rho-regulated formation and orientation of stable microtubules. Nat. Cell Biol. 3:2001;723-729.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 723-729
-
-
Palazzo, A.F.1
Cook, T.A.2
Alberts, A.S.3
Gundersen, G.G.4
-
72
-
-
0035797905
-
Cdc42, dynein, and dynactin regulate MTOC reorientation independent of Rho-regulated microtubule stabilization
-
Palazzo A.F., Joseph H.L., Chen Y.J., Dujardin D.L., Alberts A.S., Pfister K.K., Vallee R.B., Gundersen G.G. Cdc42, dynein, and dynactin regulate MTOC reorientation independent of Rho-regulated microtubule stabilization. Curr. Biol. 11:2001;1536-1541.
-
(2001)
Curr. Biol.
, vol.11
, pp. 1536-1541
-
-
Palazzo, A.F.1
Joseph, H.L.2
Chen, Y.J.3
Dujardin, D.L.4
Alberts, A.S.5
Pfister, K.K.6
Vallee, R.B.7
Gundersen, G.G.8
-
73
-
-
0032475863
-
G protein signaling events are activated at the leading edge of chemotactic cells
-
Parent C.A., Blacklock B.J., Froehlich W.M., Murphy D.B., Devreotes P.N. G protein signaling events are activated at the leading edge of chemotactic cells. Cell. 95:1998;81-91.
-
(1998)
Cell
, vol.95
, pp. 81-91
-
-
Parent, C.A.1
Blacklock, B.J.2
Froehlich, W.M.3
Murphy, D.B.4
Devreotes, P.N.5
-
74
-
-
0037178706
-
Role of formins in actin assembly: Nucleation and barbed-end association
-
Pruyne D., Evangelista M., Yang C., Bi E., Zigmond S., Bretscher A., Boone C. Role of formins in actin assembly: nucleation and barbed-end association. Science. 297:2002;612-615.
-
(2002)
Science
, vol.297
, pp. 612-615
-
-
Pruyne, D.1
Evangelista, M.2
Yang, C.3
Bi, E.4
Zigmond, S.5
Bretscher, A.6
Boone, C.7
-
75
-
-
0036672791
-
The CDM protein DOCK2 in lymphocyte migration
-
Reif K., Cyster J. The CDM protein DOCK2 in lymphocyte migration. Trends Cell Biol. 12:2002;368-373.
-
(2002)
Trends Cell Biol.
, vol.12
, pp. 368-373
-
-
Reif, K.1
Cyster, J.2
-
76
-
-
0030293886
-
Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/Rho-dependent effector pathways
-
Reif K., Nobes C.D., Thomas G., Hall A., Cantrell D.A. Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/Rho-dependent effector pathways. Curr. Biol. 6:1996;1445-1455.
-
(1996)
Curr. Biol.
, vol.6
, pp. 1445-1455
-
-
Reif, K.1
Nobes, C.D.2
Thomas, G.3
Hall, A.4
Cantrell, D.A.5
-
77
-
-
0035827310
-
Rho proteins, PI 3-kinases, and monocyte/macrophage motility
-
Ridley A.J. Rho proteins, PI 3-kinases, and monocyte/macrophage motility. FEBS Lett. 498:2001;168-171.
-
(2001)
FEBS Lett.
, vol.498
, pp. 168-171
-
-
Ridley, A.J.1
-
78
-
-
0026778133
-
The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
-
Ridley A.J., Hall A. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell. 70:1992;389-399.
-
(1992)
Cell
, vol.70
, pp. 389-399
-
-
Ridley, A.J.1
Hall, A.2
-
79
-
-
0026654125
-
The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
-
Ridley A.J., Paterson H.F., Johnston C.L., Diekmann D., Hall A. The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell. 70:1992;401-410.
-
(1992)
Cell
, vol.70
, pp. 401-410
-
-
Ridley, A.J.1
Paterson, H.F.2
Johnston, C.L.3
Diekmann, D.4
Hall, A.5
-
80
-
-
0033574722
-
The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly
-
Rohatgi R., Ma L., Miki H., Lopez M., Kirchhausen T., Takenawa T., Kirschner M.W. The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly. Cell. 97:1999;221-231.
-
(1999)
Cell
, vol.97
, pp. 221-231
-
-
Rohatgi, R.1
Ma, L.2
Miki, H.3
Lopez, M.4
Kirchhausen, T.5
Takenawa, T.6
Kirschner, M.W.7
-
81
-
-
0034683746
-
Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate
-
Rohatgi R., Ho H.Y., Kirschner M.W. Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate. J. Cell Biol. 150:2000;1299-1310.
-
(2000)
J. Cell Biol.
, vol.150
, pp. 1299-1310
-
-
Rohatgi, R.1
Ho, H.Y.2
Kirschner, M.W.3
-
82
-
-
0035854732
-
Nck and phosphatidylinositol 4,5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway
-
Rohatgi R., Nollau P., Ho H.Y., Kirschner M.W., Mayer B.J. Nck and phosphatidylinositol 4,5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway. J. Biol. Chem. 276:2001;26448-26452.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 26448-26452
-
-
Rohatgi, R.1
Nollau, P.2
Ho, H.Y.3
Kirschner, M.W.4
Mayer, B.J.5
-
83
-
-
0037124081
-
Distinct role of phosphatidylinositol 3-kinase and Rho family GTPases in Vav3-induced cell transformation, cell motility, and morphological changes
-
Sachdev P., Zeng L., Wang L.H. Distinct role of phosphatidylinositol 3-kinase and Rho family GTPases in Vav3-induced cell transformation, cell motility, and morphological changes. J. Biol. Chem. 277:2002;17638-17648.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 17638-17648
-
-
Sachdev, P.1
Zeng, L.2
Wang, L.H.3
-
84
-
-
0036141585
-
Yeast formins regulate cell polarity by controlling the assembly of actin cables
-
Sagot I., Klee S.K., Pellman D. Yeast formins regulate cell polarity by controlling the assembly of actin cables. Nat. Cell Biol. 4:2002;42-50.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 42-50
-
-
Sagot, I.1
Klee, S.K.2
Pellman, D.3
-
85
-
-
0033615966
-
Rac downregulates Rho activity: Reciprocal balance between both GTPases determines cellular morphology and migratory behavior
-
Sander E.E., ten Klooster J.P., van Delft S., van der Kammen R.A., Collard J.G. Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior. J. Cell Biol. 147:1999;1009-1022.
-
(1999)
J. Cell Biol.
, vol.147
, pp. 1009-1022
-
-
Sander, E.E.1
Ten Klooster, J.P.2
Van Delft, S.3
Van Der Kammen, R.A.4
Collard, J.G.5
-
86
-
-
0033605738
-
Inhibition of myosin light chain kinase by p21-activated kinase
-
Sanders L.C., Matsumura F., Bokoch G.M., de Lanerolle P. Inhibition of myosin light chain kinase by p21-activated kinase. Science. 283:1999;2083-2085.
-
(1999)
Science
, vol.283
, pp. 2083-2085
-
-
Sanders, L.C.1
Matsumura, F.2
Bokoch, G.M.3
De Lanerolle, P.4
-
87
-
-
0034635264
-
Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration
-
Sasaki T., Irie-Sasaki J., Jones R.G., Oliveira-dos-Santos A.J., Stanford W.L., Bolon B., Wakeham A., Itie A., Bouchard D., Kozieradzki I., Joza N., Mak T.W., Ohashi P.S., Suzuki A., Penninger J.M. Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration. Science. 287:2000;1040-1046.
-
(2000)
Science
, vol.287
, pp. 1040-1046
-
-
Sasaki, T.1
Irie-Sasaki, J.2
Jones, R.G.3
Oliveira-Dos-Santos, A.J.4
Stanford, W.L.5
Bolon, B.6
Wakeham, A.7
Itie, A.8
Bouchard, D.9
Kozieradzki, I.10
Joza, N.11
Mak, T.W.12
Ohashi, P.S.13
Suzuki, A.14
Penninger, J.M.15
-
88
-
-
0036644975
-
Guanine nucleotide exchange factors for Rho GTPases: Turning on the switch
-
Schmidt A., Hall A. Guanine nucleotide exchange factors for Rho GTPases: turning on the switch. Genes Dev. 16:2002;1587-1609.
-
(2002)
Genes Dev.
, vol.16
, pp. 1587-1609
-
-
Schmidt, A.1
Hall, A.2
-
89
-
-
0032568655
-
SMART, a simple modular architecture research tool: Identification of signaling domains
-
Schultz J., Milpetz F., Bork P., Ponting C.P. SMART, a simple modular architecture research tool: identification of signaling domains. Proc. Natl. Acad. Sci. U. S. A. 95:1998;5857-5864.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 5857-5864
-
-
Schultz, J.1
Milpetz, F.2
Bork, P.3
Ponting, C.P.4
-
90
-
-
0033577902
-
P21-Activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts
-
Sells M.A., Boyd J.T., Chernoff J. p21-Activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts. J. Cell Biol. 145:1999;837-849.
-
(1999)
J. Cell Biol.
, vol.145
, pp. 837-849
-
-
Sells, M.A.1
Boyd, J.T.2
Chernoff, J.3
-
91
-
-
0038636056
-
RhoA and Rac1 GTPases mediate the dynamic rearrangement of actin in peripheral glia
-
Sepp K.J., Auld V.J. RhoA and Rac1 GTPases mediate the dynamic rearrangement of actin in peripheral glia. Development. 130:2003;1825-1835.
-
(2003)
Development
, vol.130
, pp. 1825-1835
-
-
Sepp, K.J.1
Auld, V.J.2
-
92
-
-
0034635513
-
Polarization of chemoattractant receptor signaling during neutrophil chemotaxis
-
Servant G., Weiner O.D., Herzmark P., Balla T., Sedat J.W., Bourne H.R. Polarization of chemoattractant receptor signaling during neutrophil chemotaxis. Science. 287:2000;1037-1040.
-
(2000)
Science
, vol.287
, pp. 1037-1040
-
-
Servant, G.1
Weiner, O.D.2
Herzmark, P.3
Balla, T.4
Sedat, J.W.5
Bourne, H.R.6
-
93
-
-
0035818484
-
A RHO GTPase-mediated pathway is required during P cell migration in Caenorhabditis elegans
-
Spencer A.G., Orita S., Malone C.J., Han M. A RHO GTPase-mediated pathway is required during P cell migration in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U. S. A. 30:2001;30.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.30
, pp. 30
-
-
Spencer, A.G.1
Orita, S.2
Malone, C.J.3
Han, M.4
-
94
-
-
0036532121
-
Roles of PI3Ks in leukocyte chemotaxis and phagocytosis
-
Stephens L., Ellson C., Hawkins P. Roles of PI3Ks in leukocyte chemotaxis and phagocytosis. Curr. Opin. Cell Biol. 14:2002;203-213.
-
(2002)
Curr. Opin. Cell Biol.
, vol.14
, pp. 203-213
-
-
Stephens, L.1
Ellson, C.2
Hawkins, P.3
-
95
-
-
0035808419
-
Specific activation of LIM kinase 2 via phosphorylation of threonine 505 by ROCK, a Rho-dependent protein kinase
-
Sumi T., Matsumoto K., Nakamura T. Specific activation of LIM kinase 2 via phosphorylation of threonine 505 by ROCK, a Rho-dependent protein kinase. J. Biol. Chem. 276:2001;670-676.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 670-676
-
-
Sumi, T.1
Matsumoto, K.2
Nakamura, T.3
-
96
-
-
0034983715
-
WASP and WAVE family proteins: Key molecules for rapid rearrangement of cortical actin filaments and cell movement
-
Takenawa T., Miki H. WASP and WAVE family proteins: key molecules for rapid rearrangement of cortical actin filaments and cell movement. J. Cell Sci. 114:2001;1801-1809.
-
(2001)
J. Cell Sci.
, vol.114
, pp. 1801-1809
-
-
Takenawa, T.1
Miki, H.2
-
97
-
-
0030656619
-
Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
-
[see comments]
-
Uehata M., Ishizaki T., Satoh H., Ono T., Kawahara T., Morishita T., Tamakawa H., Yamagami K., Inui J., Maekawa M., Narumiya S. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. [see comments] Nature. 389:1997;990-994.
-
(1997)
Nature
, vol.389
, pp. 990-994
-
-
Uehata, M.1
Ishizaki, T.2
Satoh, H.3
Ono, T.4
Kawahara, T.5
Morishita, T.6
Tamakawa, H.7
Yamagami, K.8
Inui, J.9
Maekawa, M.10
Narumiya, S.11
-
98
-
-
0033128166
-
Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages
-
Vanhaesebroeck B., Jones G.E., Allen W.E., Zicha D., Hooshmand-Rad R., Sawyer C., Wells C., Waterfield M.D., Ridley A.J. Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages. Nat. Cell Biol. 1:1999;69-71.
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 69-71
-
-
Vanhaesebroeck, B.1
Jones, G.E.2
Allen, W.E.3
Zicha, D.4
Hooshmand-Rad, R.5
Sawyer, C.6
Wells, C.7
Waterfield, M.D.8
Ridley, A.J.9
-
99
-
-
0036308458
-
Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils
-
Wang F., Herzmark P., Weiner O.D., Srinivasan S., Servant G., Bourne H.R. Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils. Nat. Cell Biol. 4:2002;513-518.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 513-518
-
-
Wang, F.1
Herzmark, P.2
Weiner, O.D.3
Srinivasan, S.4
Servant, G.5
Bourne, H.R.6
-
100
-
-
0033160196
-
Cooperation between mDia1 and ROCK in Rho-induced actin reorganization
-
Watanabe N., Kato T., Fujita A., Ishizaki T., Narumiya S. Cooperation between mDia1 and ROCK in Rho-induced actin reorganization. Nat. Cell Biol. 1:1999;136-143.
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 136-143
-
-
Watanabe, N.1
Kato, T.2
Fujita, A.3
Ishizaki, T.4
Narumiya, S.5
-
102
-
-
0036308972
-
A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity
-
Weiner O.D., Neilsen P.O., Prestwich G.D., Kirschner M.W., Cantley L.C., Bourne H.R. A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity. Nat. Cell Biol. 4:2002;509-513.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 509-513
-
-
Weiner, O.D.1
Neilsen, P.O.2
Prestwich, G.D.3
Kirschner, M.W.4
Cantley, L.C.5
Bourne, H.R.6
-
103
-
-
0037155727
-
P-Rex1, a PtdIns(3,4,5)P3- and Gβγ-regulated guanine-nucleotide exchange factor for Rac
-
Welch C.E., Coadwell W.J., Ellson C.D., Ferguson G.J., Andrews S.R., Erdjument-Bromage H., Tempst P., Hawkins P.T., Stephens L.R. P-Rex1, a PtdIns(3,4,5)P3- and Gβγ-regulated guanine-nucleotide exchange factor for Rac. Cell. 108:2002;809-821.
-
(2002)
Cell
, vol.108
, pp. 809-821
-
-
Welch, C.E.1
Coadwell, W.J.2
Ellson, C.D.3
Ferguson, G.J.4
Andrews, S.R.5
Erdjument-Bromage, H.6
Tempst, P.7
Hawkins, P.T.8
Stephens, L.R.9
-
104
-
-
0029155976
-
Expression cloning of lfc, a novel oncogene with structural similarities to guanine nucleotide exchange factors and to the regulatory region of protein kinase C
-
Whitehead I., Kirk H., Tognon C., Trigo-Gonzalez G., Kay R. Expression cloning of lfc, a novel oncogene with structural similarities to guanine nucleotide exchange factors and to the regulatory region of protein kinase C. J. Biol. Chem. 270:1995;18388-18395.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 18388-18395
-
-
Whitehead, I.1
Kirk, H.2
Tognon, C.3
Trigo-Gonzalez, G.4
Kay, R.5
-
105
-
-
0032695889
-
Dependence of Dbl and Dbs transformation on MEK and NF-kappaB activation
-
Whitehead I.P., Lambert Q.T., Glaven J.A., Abe K., Rossman K.L., Mahon G.M., Trzaskos J.M., Kay R., Campbell S.L., Der C.J. Dependence of Dbl and Dbs transformation on MEK and NF-kappaB activation. Mol. Cell. Biol. 19:1999;7759-7770.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 7759-7770
-
-
Whitehead, I.P.1
Lambert, Q.T.2
Glaven, J.A.3
Abe, K.4
Rossman, K.L.5
Mahon, G.M.6
Trzaskos, J.M.7
Kay, R.8
Campbell, S.L.9
Der, C.J.10
-
106
-
-
0035178210
-
Cell motility: Can Rho GTPases and microtubules point the way?
-
Wittmann T., Waterman-Storer C.M. Cell motility: can Rho GTPases and microtubules point the way? J. Cell Sci. 114:2001;3795-3803.
-
(2001)
J. Cell Sci.
, vol.114
, pp. 3795-3803
-
-
Wittmann, T.1
Waterman-Storer, C.M.2
-
107
-
-
0032473981
-
C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180
-
Wu Y.C., Horvitz H.R. C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180. Nature. 392:1998;501-504.
-
(1998)
Nature
, vol.392
, pp. 501-504
-
-
Wu, Y.C.1
Horvitz, H.R.2
-
108
-
-
0035487807
-
C. elegans CED-12 acts in the conserved crkII/DOCK180/Rac pathway to control cell migration and cell corpse engulfment
-
Wu Y.C., Tsai M.C., Cheng L.C., Chou C.J., Weng N.Y. C. elegans CED-12 acts in the conserved crkII/DOCK180/Rac pathway to control cell migration and cell corpse engulfment. Dev. Cell. 1:2001;491-502.
-
(2001)
Dev. Cell
, vol.1
, pp. 491-502
-
-
Wu, Y.C.1
Tsai, M.C.2
Cheng, L.C.3
Chou, C.J.4
Weng, N.Y.5
-
109
-
-
0036392188
-
Distinct rac activation pathways control Caenorhabditis elegans cell migration and axon outgrowth
-
Wu Y.C., Cheng T.W., Lee M.C., Weng N.Y. Distinct rac activation pathways control Caenorhabditis elegans cell migration and axon outgrowth. Dev. Biol. 250:2002;145-155.
-
(2002)
Dev. Biol.
, vol.250
, pp. 145-155
-
-
Wu, Y.C.1
Cheng, T.W.2
Lee, M.C.3
Weng, N.Y.4
-
110
-
-
0034605099
-
Profilin enhances Cdc42-induced nucleation of actin polymerization
-
Yang C., Huang M., DeBiasio J., Pring M., Joyce M., Miki H., Takenawa T., Zigmond S.H. Profilin enhances Cdc42-induced nucleation of actin polymerization. J. Cell Biol. 150:2000;1001-1012.
-
(2000)
J. Cell Biol.
, vol.150
, pp. 1001-1012
-
-
Yang, C.1
Huang, M.2
Debiasio, J.3
Pring, M.4
Joyce, M.5
Miki, H.6
Takenawa, T.7
Zigmond, S.H.8
-
111
-
-
0033533613
-
AlphaPIX nucleotide exchange factor is activated by interaction with phosphatidylinositol 3-kinase
-
Yoshii S., Tanaka M., Otsuki Y., Wang D.Y., Guo R.J., Zhu Y., Takeda R., Hanai H., Kaneko E., Sugimura H. alphaPIX nucleotide exchange factor is activated by interaction with phosphatidylinositol 3-kinase. Oncogene. 18:1999;5680-5690.
-
(1999)
Oncogene
, vol.18
, pp. 5680-5690
-
-
Yoshii, S.1
Tanaka, M.2
Otsuki, Y.3
Wang, D.Y.4
Guo, R.J.5
Zhu, Y.6
Takeda, R.7
Hanai, H.8
Kaneko, E.9
Sugimura, H.10
-
112
-
-
0035668525
-
Dbl family guanine nucleotide exchange factors
-
Zheng Y. Dbl family guanine nucleotide exchange factors. Trends Biochem. Sci. 26:2001;724-732.
-
(2001)
Trends Biochem. Sci.
, vol.26
, pp. 724-732
-
-
Zheng, Y.1
-
113
-
-
0028338545
-
Activation of phosphoinositide 3-kinase activity by Cdc42Hs binding to p85
-
Zheng Y., Bagrodia S., Cerione R.A. Activation of phosphoinositide 3-kinase activity by Cdc42Hs binding to p85. J. Biol. Chem. 269:1994;18727- 18730.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 18727-18730
-
-
Zheng, Y.1
Bagrodia, S.2
Cerione, R.A.3
-
114
-
-
0035487646
-
The C. elegans PH domain protein CED-12 regulates cytoskeletal reorganization via a Rho/Rac GTPase signaling pathway
-
Zhou Z., Caron E., Hartwieg E., Hall A., Horvitz H.R. The C. elegans PH domain protein CED-12 regulates cytoskeletal reorganization via a Rho/Rac GTPase signaling pathway. Dev. Cell. 1:2001;477-489.
-
(2001)
Dev. Cell
, vol.1
, pp. 477-489
-
-
Zhou, Z.1
Caron, E.2
Hartwieg, E.3
Hall, A.4
Horvitz, H.R.5
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