Cytoplasmic dynein-associated structures move bidirectionally in vivo

Journal of Cell Science

Volumn 115, Issue 7, 2002, Pages 1453-1460

  Ma, Shuo ^a   Chisholm, Rex L ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Cytoplasmic dynein; Green fluorescent protein; Live cell imaging; Molecular motor regulation; Organelle; Transport

Indexed keywords

DYNEIN ADENOSINE TRIPHOSPHATASE; GREEN FLUORESCENT PROTEIN; KINESIN;

ARTICLE; CELL MOTION; CELL ORGANELLE; CONTROLLED STUDY; CYTOPLASM VESICLE; DICTYOSTELIUM; IN VIVO CULTURE; INTRACELLULAR TRANSPORT; MICROFILAMENT; MICROTUBULE; MOLECULAR DYNAMICS; MOTOR ACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; VELOCITY;

ANIMALS; CYTOPLASM; DICTYOSTELIUM; DYNEIN ATPASE; GREEN FLUORESCENT PROTEINS; LUMINESCENT PROTEINS; MICROTUBULES; MODELS, BIOLOGICAL; MOVEMENT; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

DICTYOSTELIUM;

EID: 0036538577     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. Real-time observations of microtubule dynamic instability in living cells
2. A developmentally regulated kinesin-related motor protein from Dictyostelium discoideum
3. Functional analysis of dynactin and cytoplasmic dynein in slow axonal transport
4. Cytoplasmic dynein is associated with slow axonal transport
5. Differential phosphorylation in vivo of cytoplasmic dynein associated with anterogradely moving organelles
6. Phase dynamics at microtubule ends: The coexistence of microtubule length changes and treadmilling
7. Dynein-mediated cargo transport in vivo. A switch controls travel distance
8. Analysis of G alpha 4, a G-protein subunit required for multicellular development in Dictyostelium
9. Kinesin and dynein superfamily proteins and the mechanism of organelle transport
10. Brain dynein (MAP1C) localizes on both anterogradely and retrogradely transported membranous organelles in vivo
11. Affinity chromatography demonstrates a direct binding between cytoplasmic dynein and the dynactin complex
12. Dynactin increases the processivity of the cytoplasmic dynein motor
13. Cytoplasmic dynein heavy chain is an essential gene product in Dictyostelium
14. Identification and immunolocalization of cytoplasmic dynein in Dictyostelium
15. Phosphorylation of kinesin in vivo correlates with organelle association and neurite outgrowth
16. Cytoplasmic dynein undergoes intracellular redistribution concomitant with phosphorylation of the heavy chain in response to serum starvation and okadaic acid
17. Kinesin is the motor for microtubule-mediated Golgi-to-ER membrane traffic
18. Identification of a microtubule-based cytoplasmic motor in the nematode C. elegans
19. Dynein intermediate chain mediated dynein-dynactin interaction is required for interphase microtubule organization and centrosome replication and separation in Dictyostelium
20. Changes in kinesin distribution and phosphorylation occur during regulated secretion in pancreatic acinar cells
21. Identification of a kinesin-like microtubule based motor protein in Dictyostelium discoideum
22. Regulation of kinesin activity by phosphorylation of kinesin-associated proteins
23. Dynamic instability of microtubule growth
24. Cell cycle regulation of dynein association with membranes modulates microtubule-based organelle transport
25. Localization of kinesin and cytoplasmic dynein in cultured melanophores from Atlantic cod, Gadus morhua
26. Expression of a myosin regulatory light chain phosphorylation site mutant complements the cytokinesis and developmental defects of Dictyostelium RMLC null cells
27. Variables controlling the expression level of exogenous genes in Dictyostelium
28. MAP 1C is a microtubule-activated ATPase which translocates microtubules in vitro and has dynein-like properties
29. CLIP-170 highlights growing microtubule ends in vivo
30. In vitro microtubule-based organelle transport in wild-type Dictyostelium and cells overexpressing a truncated dynein heavy chain
31. Reconstitution of membrane transport powered by a novel dimeric kinesin motor of the Unc104/KIF1A family purified from Dictyostelium
32. Fast transport of neurofilament protein along microtubules in squid axoplasm
33. ER-to-Golgi transport visualized in living cells
34. Dynein, dynactin, and kinesin II's interaction with microtubules is regulated during bidirectional organelle transport
35. Regulated bidirectional motility of melanophore pigment granules along microtubules in vitro
36. Dynamic association of cytoplasmic dynein heavy chain 1a with the Golgi apparatus and intermediate compartment
37. Movements of intracellular particles in undifferentiated amebae of Dictyostelium discoideum
38. Neurofilaments are transported rapidly but intermittently in axons: Implications for slow axonal transport
39. Direct observation of microtubule dynamics in living cells
40. The phosphorylation of kinesin regulates its binding to synaptic vesicles
41. Dynein is the motor for retrograde axonal transport of organelles
42. Two activators of microtubule-based vesicle transport
43. Microtubule-dependent plus- and minus-end-directed motilities are competing processes for nuclear targeting of adenovirus
44. Role of dynactin in endocytic traffic: Effects of dynamitin overexpression and colocalization with CLIP-170
45. Cytoplasmic dynein binds dynactin through a direct interaction between the intermediate chains and p150Glued
46. Rapid movement of axonal neurofilaments interrupted by prolonged pauses
47. Opposing motor activities of dynein and kinesin determine retention and transport of MHC class II-containing compartments
48. Dynamics of cytoplasmic dynein in living cells and the effect of a mutation in the dynactin complex actin-related protein Arp1
49. The herpes simplex virus 1 U(L)34 protein interacts with a cytoplasmic dynein intermediate chain and targets nuclear membrane
50. Localization of actin and myosin for the study of ameboid movement in Dictyostelium using improved immunofluorescence