The Rho GTPase and a putative RhoGEF mediate a signaling pathway for the cell shape changes in Drosophila gastrulation

Cell

Volumn 91, Issue 7, 1997, Pages 905-915

  Barrett, Kathy ^a   Leptin, Maria ^b   Settleman, Jeffrey ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL SHAPE; DROSOPHILA; EMBRYO DEVELOPMENT; GASTRULATION; MOLECULAR CLONING; MORPHOGENESIS; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALIA; HEXAPODA;

EID: 0031443277     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)80482-1     Document Type: Article

References (57)

1. Brönner, G., and Jäckle, H. (1991). Control and function of terminal gap gene activity in the posterior region of the Drosophila embryo. Mech. Dev. 35, 205-211.
2. Buhl, A.M., Johnson, N.L., Dhanasekaran, N., and Johnson, G.L. (1995). Gα12and Gα13 stimulate Rho-dependent stress fiber formation and focal adhesion assembly. J. Biol. Chem. 270, 24631-24634.
3. Campos-Ortega, J.A., and Hartenstein, V. (1985). The Embryonic Development of Drosophila melanogaster (Berlin: Springer-Verlag).
4. D1] dominant female-sterile insertions in Drosophila and their use in generating germ-line chimeras. Development 119, 1359-1369.
5. Costa, M., Wilson, E.T., and Wieschaus, E. (1994). A putative cell signal encoded by the folded gastrulation gene coordinates cell shape changes during Drosophila gastrulation. Cell 76, 1075-1089.
6. Crespo, P., Schuebel, K.E., Ostrom, A.A., Gutkind, J.S., and Bustelo, X.R. (1997). Phosphotyrosine-dependent activation of Rac-1 GDP/ GTP exchange by the vav proto-oncogene product. Nature 385, 169-172.
7. Dutartre, H., Davoust, J., Gorvel, J.-P., and Chavrier, P.(1996).Cytokynesis arrest and redistribution of actin-cytoskeleton regulatory components in cells expressing the Rho GTPase CDC42hs. J. Cell Sci. 109, 367-377.
8. Eaton, S., Auvinen, P., Luo, L., Jan, Y.N., and Simons, K. (1995). CDC42 and Rac1 control different actin-dependent processes in the Drosophila wing disc epithelium. J. Cell Biol. 131, 151-164.
9. Eaton, S., Wepf, R., and Simons, K. (1996). Roles for Rac1 and Cdc42 in planar polarization and hair outgrowth in the wing of Drosophila. J. Cell Biol. 135, 1277-12789.
10. Egan, S.E., Giddings, B.W., László, B., Brooks, M., Sizeland, A.M., and Weinberg, R.A. (1993). Association of Sos Ras nucleotide exchange protein with Grb2-Sem-5 is implicated in tyrosine kinase signal transduction and transformation. Nature 363, 45-51.
11. Feig, L.A., and Cooper, G.M. (1988). Inhibition of NIH3T3cell proliferation by a mutant ras protein with preferential affinity for GDP. Mol. Cell. Biol. 8, 3235-3243.
12. Fischer-Vize, J.A., Rubin, G.M., and Lehman, R. (1992). The fat facets gene is required for Drosophila eye and embryo development. Development 116, 985-1000.
13. Gebbink, M.F., Kranenburg, O., Poland, M., van Horck, F.P., Houssa, B., and Moolenaar, W.H. (1997). Identification of a novel, putative Rho-specific GDP/GTP exchange factor and a RhoA-binding protein: control of neuronal morphology. J. Cell Biol. 137, 1603-1613.
14. Gulbins, E., Coggeshall, K.M., Baier, G., Telford, D., Langlet, C., Baier-Bitterlich, G., Bonnefoy-Berard, N., Burn, P., Wittinghofer, A., and Altman, A. (1994). Direct stimulation of Vav guanine nucleotide exchange activity for Ras by phorbol esters and diglycerides. Mol. Cell. Biol. 14, 4749-4758.
15. Hafen, E., Basler, K., Edstroem, J.E., and Rubin, G.M. (1987). Sevenless, a cell-specific homeotic gene of Drosophila, encodes a putative transmembrane receptor with a tyrosine kinase domain. Science 236, 55-63.
16. Han, J., Das, B., Wei, W., Van Aelst, L., Mosteller, R.D., Khosravi-Far, R., Westwick, J.K., Der, C.J., and Broek, D. (1997). Lck regulates Vav activation of members of the Rho family of GTPases. Mol. Cell Biol. 17, 1346-1353.
17. Harden, N., Loh, H.Y., Chia, W., and Lim, L. (1995). A dominant inhibitory version of the small GTP-binding protein Rac disrupts cytoskeletal structures and inhibits developmental cell shape changes in Drosophila. Development 121, 903-914.
18. Hariharan, I.K., Hu, K.Q., Asha, H., Quintanilla, A., Ezzell, R.M., and Settleman, J. (1995). Characterization of rho GTPase homologues in Drosophila melanogaster. overexpressing Rho1 causes a late developmental defect. EMBO J. 14, 292-302.
19. Hart, M.J., Eva, A., Evans, T., Aaronson, S.A., and Cerione, R.A. (1991). Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product. Nature 354, 311-314.
20. Hay, B.A., Wolff, T., and Rubin, G.M. (1994). Expression of baculovirus p35 prevents cell death in Drosophila. Development 120, 2121-2129.
21. Hiromi, Y., Kuroiwa, A., and Gehring, W.J. (1985). Control elements of the Drosophila segmentation gene fushi tarazu. Cell 43, 603-613.
22. Huang, K.P. (1989). The mechanism of protein kinase C activation. Trends Neurosci. 12, 425-432.
23. Kimmel, B.E., Heberlein, U., and Rubin, G.M. (1990). The homeo domain protein rough is expressed in a subset of cells in the developing Drosophila eye where it can specify photoreceptor cell subtype. Genes Dev. 4, 712-727.
24. Kozma, R., Ahmed, S., Best, A., and Lim, L. (1995). The Ras-related protein CDC42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts. Mol. Cell. Biol. 15, 1942-1952.
25. Leptin, M., and Grunewald, B. (1990). Cell shape changes during gastrulation in Drosophila. Development 110, 73-84.
26. Leptin, M. (1991). Twist and snail as positive and negative regulators during Drosophila mesoderm development. Genes Dev. 5, 1568-1576.
27. Leptin, M. (1995). Drosophila gastrulation: from pattern formation to morphogenesis. Annu. Rev. Cell. Dev. Biol. 11, 189-212.
28. Luo, L., Liao, Y.J., Jan, L.Y., and Jan, Y.N. (1994). Distinct morphogenetic functions of similar small GTPases: Drosophila Dra1 is involved in axonal outgrowth and myoblast fusion. Genes Dev. 8, 1787-1802.
29. Murphy, A.M., and Montell, D.J. (1996). Cell type-specific roles for Cdc42, Rac, and RhoL in Drosophila oogenesis. J. Cell Biol. 133, 617-630.
30. Nambu, J.R., Lewis, J.O., Wharton, K.A., Jr., and Crews, ST. (1991). The Drosophila single-minded gene encodes a helix-loop-helix protein that acts as a master regulator of CNS midline development. Cell 67, 1157-1167.
31. Narumiya, S., and Morii, N. (1993). Rho gene products, botulinim C3 exoenzyme, and cell adhesion. Cell. Signal. 5, 9-19.
32. Nobes, C., and Hall, A. (1994). Regulation and function of the Rho subfamily of small GTPases. Curr. Opin. Gen. Dev. 4, 77-81.
33. Nobes, C.D., and Hall, A. (1995). Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 81, 53-62.
34. Olson, M.F., Ashworth, A., and Hall, A. (1995). An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1. Science 269, 1270-1272.
35. Parks, S., and Wieschaus, E. (1991). The Drosophila gastrulation gene concertina encodes a Gα-like protein. Cell 64, 447-458.
36. Patel, N.H. (1994). Imaging neuronal subsets and other cell types in whole-mount Drosophila embryos and larvae using antibody probes. In Drosophila melanogaster. Practical Uses in Cell and Molecular Biology, L.S.B. Goldstein and E.A. Fyrberg, eds. (San Diego: Academic Press, Inc.), pp. 445-487.
37. Ponting, C.P., Phillips, C., Davies, K.E., and Blake, D.J. (1997). PDZ domains: targeting signaling molecules to sub-membranous sites. Bioessays 19, 469-79.
38. Ridley, A.J. (1995). Rho-related proteins: actincytoskeleton and cell cycle. Curr. Opin. Gen. Dev. 5, 24-30.
39. Ridley, A.J. (1996). Rho: theme and variations. Curr. Biol. 6, 1256-1264.
40. Ridley, A.J., and Hall, A. (1992). The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 70, 389-399.
41. Ridley, A.J., Paterson, H.F., Johnston, C.L., Diekmann, D., and Hall, A. (1992). The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell 70, 401-410.
42. Schmalzing, G., Richter, H.-P., Hansen, A., Schwarz, W., Just, I., and Aktories, K. (1995). Involvement of the GTP binding protein Rho in constitutive endocytosis in Xenopus laevis oocytes. J. Cell Biol. 130, 1319-1332.
43. Smrcka, A.V., Hepler, J.R., Brown, K.O., and Sternweis, P.C. (1991). Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq. Science 251, 804-807.
44. Sone, M., Hoshino, M., Suzuki, E., Kuroda, S., Kaibuchi, K., Nakagoshi, H., Saigo, K., Nabeshima, Y., and Hama, C. (1997). Still life, a protein in synaptic terminals of Drosophila homologous to GDP-GTP exchangers. Science 275, 543-547.
45. Strutt, D.I., Weber, U., and Mlodzik, M. (1997). The role of RhoA in tissue polarity and Frizzled signaling. Nature 387, 292-295.
46. Sullivan, W., and Theurkauf, W.E. (1995). The cytoskeleton and morphogenesis of the early Drosophila embryo. Curr. Opin. Cell Biol. 7, 18-22.
47. Sweeton, D., Parks, S., Costa, M., and Wieschaus, E. (1991).Gastrulationin Drosophila: the formation of the ventral furrow and posterior midgut invaginations. Development 112, 775-789.
48. Takaishi, K., Kikuchi, A., Kuroda, S., Kotani, K., Sasaki, T., and Takai, Y. (1993). Involvement of rho p21 and its inhibitory GDP/GTP exchange protein (rhoGDI) in cell motility. Mol. Cell. Biol. 13, 72-79.
49. Tapon, N., and Hall, A. (1997). Rho, Rac and Cdc42 GTPases regulate the organization of the actin cytoskeleton. Curr. Opin. Cell Biol. 9, 86-92.
50. Tautz, D., and Pfeifle, C. (1989). A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. Chromosoma 98, 81-85.
51. Thomas, G.H., and Kiehart, D.P. (1994). Beta heavy-spectrin has a restricted tissue and subcellular distribution during Drosophila embryogenesis. Development 120, 2039-2050.
52. Tomlinson, A., and Ready, D.F. (1987). Cell fate in the Drosophila ommatidium. Dev. Biol. 123, 264-275.
53. Wahl, M.I., Olashaw, N.E., Nishibe, S., Rhee, S.G., Pledger, W.J., and Carpenter, G. (1989). Platelet-derived growth factor induces rapid and sustained tyrosine phosphorylation of phospholipase C-gamma in quiescent BALB/c 3T3 cells. Mol. Cell. Biol. 9, 2934-2943.
54. Werner, L.A., and Manseau, L.J. (1997). A Drosophila gene with predicted rhoGEF, pleckstrin homology and SH3 domains is highly expressed in morphogenic tissues. Gene 187, 107-114.
55. Whitehead, I.P., Campbell, S., Rossman, K.L., and Der, C.J. (1997). Dbl family proteins. Biochim. Biophys. Acta 1332, F1-F23.
56. Young, P.E., Pesacreta, T.C., and Kiehart, D.P. (1991). Dynamic changes in the distribution of cytoplasmic myosin during Drosophila embryogenesis. Development , 111, 1-14.
57. Zheng, Y., Zangrilli, D., Cerione, R.A., and Eva, A. (1996). The pleckstrin homology domain mediates transformation by oncogenic dbl through specific intracellular targeting. J. Biol. Chem. 271, 19017-19020.