-
1
-
-
0017029812
-
Clonal variation and aging of diploid fibroblasts
-
Absher PM and Absher RG (1976) Clonal variation and aging of diploid fibroblasts. Exp Cell Res 103: 247-255
-
(1976)
Exp. Cell Res.
, vol.103
, pp. 247-255
-
-
Absher, P.M.1
Absher, R.G.2
-
2
-
-
0024362809
-
Human telomeres contain at least three types of G-rich repeat distributed non-randomly
-
Allshire RC, Dempster M and Hastie ND (1989) Human telomeres contain at least three types of G-rich repeat distributed non-randomly. Nucleic Acids Res 17: 4611-4627
-
(1989)
Nucleic Acids Res.
, vol.17
, pp. 4611-4627
-
-
Allshire, R.C.1
Dempster, M.2
Hastie, N.D.3
-
3
-
-
0026460896
-
Telomere length predicts replicative capacity of human fibroblasts
-
Allsopp RC, Vaziri H, Patterson C, Goldstein S, Younglai EV, Futcher AB, Greider CW and Harley CB (1992) Telomere length predicts replicative capacity of human fibroblasts. Proc Natl Acad Sci USA 89: 10114-10118
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 10114-10118
-
-
Allsopp, R.C.1
Vaziri, H.2
Patterson, C.3
Goldstein, S.4
Younglai, E.V.5
Futcher, A.B.6
Greider, C.W.7
Harley, C.B.8
-
4
-
-
0035075342
-
Functional and dysfunctional roles of quadruplex DNA in cells
-
Arthanari H and Bolton PH (2001) Functional and dysfunctional roles of quadruplex DNA in cells. Chem Biol 8: 221-230
-
(2001)
Chem. Biol.
, vol.8
, pp. 221-230
-
-
Arthanari, H.1
Bolton, P.H.2
-
5
-
-
0035964864
-
Strand-specific postreplicative processing of mammalian telomeres
-
Bailey SM, Cornfort MN, Kurimasa A, Chen DJ and Goodwin EH (2001 ) Strand-specific postreplicative processing of mammalian telomeres. Science 293: 2462-2465
-
(2001)
Science
, vol.293
, pp. 2462-2465
-
-
Bailey, S.M.1
Cornfort, M.N.2
Kurimasa, A.3
Chen, D.J.4
Goodwin, E.H.5
-
6
-
-
0028880546
-
Mechanisms underlying telomere repeat turnover, revealed by hypervariable variant repeat distribution patterns in the human Xp/Yp telomere
-
Baird DM, Jeffreys AJ and Royle NJ (1995) Mechanisms underlying telomere repeat turnover, revealed by hypervariable variant repeat distribution patterns in the human Xp/Yp telomere. EMBO J 14: 5433-5443
-
(1995)
EMBO J.
, vol.14
, pp. 5433-5443
-
-
Baird, D.M.1
Jeffreys, A.J.2
Royle, N.J.3
-
7
-
-
0033924643
-
High levels of sequence polymorphism and linkage disequilibrium at the telomere of 12q: Implications for telomere biology and human evolution
-
Baird DM, Coleman J, Rosser ZH and Royle NJ (2000) High levels of sequence polymorphism and linkage disequilibrium at the telomere of 12q: implications for telomere biology and human evolution. Am J Hum Genet 66: 235-250
-
(2000)
Am. J. Hum. Genet.
, vol.66
, pp. 235-250
-
-
Baird, D.M.1
Coleman, J.2
Rosser, Z.H.3
Royle, N.J.4
-
8
-
-
0037313185
-
Extensive allelic variation and ultrashort telomeres in senescent human cells
-
Baird DM, Rowson J, Wynford-Thomas D and Kipling D (2003) Extensive allelic variation and ultrashort telomeres in senescent human cells. Nat Genet 33: 203-207
-
(2003)
Nat. Genet.
, vol.33
, pp. 203-207
-
-
Baird, D.M.1
Rowson, J.2
Wynford-Thomas, D.3
Kipling, D.4
-
9
-
-
0027990373
-
Structure and stability of human telomeric sequence
-
Balagurumoorthy P and Brahmachari SK (1994) Structure and stability of human telomeric sequence. J Biol Chem 269: 21858-21869
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 21858-21869
-
-
Balagurumoorthy, P.1
Brahmachari, S.K.2
-
10
-
-
0018343451
-
Deteriorating collagen synthesis and cell ultrastructure accompanying senescence of human normal and Werner's syndrome fibroblast cell strains
-
Basler JW, David JD and Agris PF (1979) Deteriorating collagen synthesis and cell ultrastructure accompanying senescence of human normal and Werner's syndrome fibroblast cell strains. Exp Cell Res 118: 73-84
-
(1979)
Exp. Cell Res.
, vol.118
, pp. 73-84
-
-
Basler, J.W.1
David, J.D.2
Agris, P.F.3
-
11
-
-
0027090432
-
Terminal differentiation, aging, apoptosis, and spontaneous transformation in fibroblast stem cell systems in vivo and in vitro
-
Bayreuther K, Francz PI, Gogol J and Kontermann K (1992) Terminal differentiation, aging, apoptosis, and spontaneous transformation in fibroblast stem cell systems in vivo and in vitro. Ann N Y Acad Sci 663: 167-179
-
(1992)
Ann. N. Y. Acad. Sci.
, vol.663
, pp. 167-179
-
-
Bayreuther, K.1
Francz, P.I.2
Gogol, J.3
Kontermann, K.4
-
12
-
-
0036569628
-
Comparing telomere length of sister chromatids in human lymphocytes using three-dimensional confocal microscopy
-
Bekaert S, Koll S, Thas O and van Oostveldt P (2002) Comparing telomere length of sister chromatids in human lymphocytes using three-dimensional confocal microscopy. Cytometry 48: 34-44
-
(2002)
Cytometry
, vol.48
, pp. 34-44
-
-
Bekaert, S.1
Koll, S.2
Thas, O.3
van Oostveldt, P.4
-
13
-
-
0018270179
-
Loss of division potential in vitro: Aging or differentiation?
-
Bell E, Marek LF, Levinstone DS, Merrill C, Sher S, Young IT and Eden M ( 1978) Loss of division potential in vitro: aging or differentiation? Science 202: 1158-1163
-
(1978)
Science
, vol.202
, pp. 1158-1163
-
-
Bell, E.1
Marek, L.F.2
Levinstone, D.S.3
Merrill, C.4
Sher, S.5
Young, I.T.6
Eden, M.7
-
14
-
-
0017166058
-
Specific chromosome aberrations in senescent fibroblast cell lines derived from human embryos
-
Benn PA (1976) Specific chromosome aberrations in senescent fibroblast cell lines derived from human embryos. Am J Hum Genet 28: 465-473
-
(1976)
Am. J. Hum. Genet.
, vol.28
, pp. 465-473
-
-
Benn, P.A.1
-
15
-
-
0017717672
-
Population kinetics of chromosomally abnormal human fibroblast subpopulations
-
Benn PA (1977) Population kinetics of chromosomally abnormal human fibroblast subpopulations. Cytogenet Cell Genet 19: 136-145
-
(1977)
Cytogenet. Cell Genet.
, vol.19
, pp. 136-145
-
-
Benn, P.A.1
-
16
-
-
0032832195
-
Physical and functional interaction between p53 and the Werner's syndrome protein
-
Blander G, Kipnis J, Leal JFM, Yu C-E, Schellenberg GD and Oren M (1999) Physical and functional interaction between p53 and the Werner's syndrome protein. J Biol Chem 274: 29463-29469
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 29463-29469
-
-
Blander, G.1
Kipnis, J.2
Leal, J.F.M.3
Yu, C.-E.4
Schellenberg, G.D.5
Oren, M.6
-
17
-
-
0037185024
-
DNA damage-induced translocation of the Werner helicase is regulated by acetylation
-
Blander G, Zalle N, Daniely Y, Taplick J, Gray MD and Oren M (2002) DNA damage-induced translocation of the Werner helicase is regulated by acetylation. J Biol Chem 277: 50934-50940
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 50934-50940
-
-
Blander, G.1
Zalle, N.2
Daniely, Y.3
Taplick, J.4
Gray, M.D.5
Oren, M.6
-
18
-
-
0040436076
-
Functional and physical interaction between WRN helicase and human replication protein A
-
Brosh RM jr, Orren DK, Nehlin JO, Ravn PH, Kenny MK, Machwe A and Bohr VA (1999) Functional and physical interaction between WRN helicase and human replication protein A. J Biol Chem 274: 18341-18350
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 18341-18350
-
-
Brosh Jr., R.M.1
Orren, D.K.2
Nehlin, J.O.3
Ravn, P.H.4
Kenny, M.K.5
Machwe, A.6
Bohr, V.A.7
-
19
-
-
0035887046
-
Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity
-
Brosh RM jr, von Kobbe C, Sommers JA, Karmakar P, Opresko PL, Piotrowski J, Dianova I, Dianov GL and Bohr VA (2001a) Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity. EMBO J 20: 5791-5801
-
(2001)
EMBO J.
, vol.20
, pp. 5791-5801
-
-
Brosh Jr., R.M.1
von Kobbe, C.2
Sommers, J.A.3
Karmakar, P.4
Opresko, P.L.5
Piotrowski, J.6
Dianova, I.7
Dianov, G.L.8
Bohr, V.A.9
-
20
-
-
0035860775
-
p53 modulates the exonuclease activity of Werner syndrome protein
-
Brosh RM jr, Karmakar P, Sommers JA, Yang Q, Wang XW, Spillare EA, Harris CC and Bohr VA (2001b) p53 modulates the exonuclease activity of Werner syndrome protein. J Biol Chem 276: 35093-35102
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 35093-35102
-
-
Brosh Jr., R.M.1
Karmakar, P.2
Sommers, J.A.3
Yang, Q.4
Wang, X.W.5
Spillare, E.A.6
Harris, C.C.7
Bohr, V.A.8
-
21
-
-
0035793552
-
Unwinding of a DNA triple helix by the Werner and Bloom syndrome helicases
-
Brosh RM jr, Majumdar A, Desai S, Hickson ID, Bohr VA and Seidman MM (2001c) Unwinding of a DNA triple helix by the Werner and Bloom syndrome helicases. J Biol Chem 276: 3024-3030
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3024-3030
-
-
Brosh Jr., R.M.1
Majumdar, A.2
Desai, S.3
Hickson, I.D.4
Bohr, V.A.5
Seidman, M.M.6
-
23
-
-
0037189485
-
Biochemical characterization of the DNA substrate specificity of Werner syndrome helicase
-
Brosh RM jr, Waheed J and Sommers JA (2002b) Biochemical characterization of the DNA substrate specificity of Werner syndrome helicase. J Biol Chem 277: 23236-23245
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 23236-23245
-
-
Brosh Jr., R.M.1
Waheed, J.2
Sommers, J.A.3
-
24
-
-
0018886535
-
Selective elimination of proliferating cells in human diploid cell cultures by treatment with BrdU, 33258 Hoechst and visible light
-
Burmer GC and Norwood TH (1980) Selective elimination of proliferating cells in human diploid cell cultures by treatment with BrdU, 33258 Hoechst and visible light. Mech Ageing Dev 12: 151-159
-
(1980)
Mech. Ageing Dev.
, vol.12
, pp. 151-159
-
-
Burmer, G.C.1
Norwood, T.H.2
-
25
-
-
0027243084
-
Parallel DNA triplexes, homologous recombination, and other homology-dependent DNA interactions
-
Camerini-Otero RD and Hsieh P (1993) Parallel DNA triplexes, homologous recombination, and other homology-dependent DNA interactions. Cell 73: 217-223
-
(1993)
Cell
, vol.73
, pp. 217-223
-
-
Camerini-Otero, R.D.1
Hsieh, P.2
-
26
-
-
0033119701
-
Defending genome integrity during DNA replication: A proposed role for RecQ family helicases
-
Chakraverty RK and Hickson ID (1999) Defending genome integrity during DNA replication: a proposed role for RecQ family helicases. Bioessays 21: 286-294
-
(1999)
Bioessays
, vol.21
, pp. 286-294
-
-
Chakraverty, R.K.1
Hickson, I.D.2
-
27
-
-
0035809934
-
Evidence for a replication function of FFA- 1, the Xenopus orthologue of Werner syndrome protein
-
Chen C-Y, Graham J and Yan H (2001) Evidence for a replication function of FFA- 1, the Xenopus orthologue of Werner syndrome protein. J Cell Biol 152: 985-996
-
(2001)
J. Cell Biol.
, vol.152
, pp. 985-996
-
-
Chen, C.-Y.1
Graham, J.2
Yan, H.3
-
28
-
-
0035069410
-
Telomerase expression prevents replicative senescence but does not fully reset mRNA expression patterns in Werner syndrome cell strains
-
Choi D, Whittier PS, Oshima J and Funk WD (2001) Telomerase expression prevents replicative senescence but does not fully reset mRNA expression patterns in Werner syndrome cell strains. FASEB J 15: 1014-1020
-
(2001)
FASEB J.
, vol.15
, pp. 1014-1020
-
-
Choi, D.1
Whittier, P.S.2
Oshima, J.3
Funk, W.D.4
-
29
-
-
0035853104
-
Recombination-mediated lengthening of terminal telomeric repeats requires the Sgs1 DNA helicase
-
Cohen H and Sinclair DA (2001) Recombination-mediated lengthening of terminal telomeric repeats requires the Sgs1 DNA helicase. Proc Natl Acad Sci USA 98: 3174-3179
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 3174-3179
-
-
Cohen, H.1
Sinclair, D.A.2
-
30
-
-
0032833672
-
The plasticity of human telomeres demonstrated by a hypervariable telomere repeat array that is located on some copies of 16p and 16q
-
Coleman J, Baird DM and Royle NJ (1999) The plasticity of human telomeres demonstrated by a hypervariable telomere repeat array that is located on some copies of 16p and 16q. Hum Mol Genet 8: 1637-1646
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 1637-1646
-
-
Coleman, J.1
Baird, D.M.2
Royle, N.J.3
-
31
-
-
0034231844
-
Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest
-
Constantinou A, Tarsounas M, Karow JK, Brosh RM, Bohr VA, Hickson ID and West SC (2000) Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest. EMBO Rep 1: 80-84
-
(2000)
EMBO Rep.
, vol.1
, pp. 80-84
-
-
Constantinou, A.1
Tarsounas, M.2
Karow, J.K.3
Brosh, R.M.4
Bohr, V.A.5
Hickson, I.D.6
West, S.C.7
-
32
-
-
0020023663
-
Characterization of long patch excision repair of DNA in ultraviolet-irradiated Escherichia coli: An inducible function under Rec-Lex control
-
Cooper PK (1982) Characterization of long patch excision repair of DNA in ultraviolet-irradiated Escherichia coli: an inducible function under Rec-Lex control. Mol Gen Genet 185: 189-197
-
(1982)
Mol. Gen. Genet.
, vol.185
, pp. 189-197
-
-
Cooper, P.K.1
-
33
-
-
0015505905
-
Heterogeneity of patch size in repair replicated DNA in Escherichia coli
-
Cooper PK and Hanawalt PC (1972) Heterogeneity of patch size in repair replicated DNA in Escherichia coli. J Mol Biol 67: 1-10
-
(1972)
J. Mol. Biol.
, vol.67
, pp. 1-10
-
-
Cooper, P.K.1
Hanawalt, P.C.2
-
34
-
-
0034655912
-
Ku complex interacts with and stimulates the Werner protein
-
Cooper MP, Machwe A, Orren DK, Brosh RM, Ramsden D and Bohr VA (2000) Ku complex interacts with and stimulates the Werner protein. Genes Dev 14: 907-912
-
(2000)
Genes Dev.
, vol.14
, pp. 907-912
-
-
Cooper, M.P.1
Machwe, A.2
Orren, D.K.3
Brosh, R.M.4
Ramsden, D.5
Bohr, V.A.6
-
35
-
-
0032740855
-
RecQ and RecJ process blocked replication forks prior to the resumption of replication in UV-irradiated Escherichia coli
-
Courcelle J and Hanawalt PC (1999) RecQ and RecJ process blocked replication forks prior to the resumption of replication in UV-irradiated Escherichia coli. Mol Gen Genet 262: 543-551
-
(1999)
Mol. Gen. Genet.
, vol.262
, pp. 543-551
-
-
Courcelle, J.1
Hanawalt, P.C.2
-
36
-
-
0035902521
-
Participation of recombination proteins in rescue of arrested replication forks in UV-irradiated Escherichia coli need not involve recombination
-
Courcelle J and Hanawalt PC (2001) Participation of recombination proteins in rescue of arrested replication forks in UV-irradiated Escherichia coli need not involve recombination. Proc Natl Acad Sci USA 98: 8196-8202
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 8196-8202
-
-
Courcelle, J.1
Hanawalt, P.C.2
-
37
-
-
0030890705
-
recF and recR are required for the resumption of replication at DNA replication forks in Escherichia coli
-
Courcelle J, Carswell-Crumpton C and Hanawalt PC (1997) recF and recR are required for the resumption of replication at DNA replication forks in Escherichia coli. Proc Natl Acad Sci USA 94: 3714-3719
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 3714-3719
-
-
Courcelle, J.1
Carswell-Crumpton, C.2
Hanawalt, P.C.3
-
38
-
-
0035822641
-
Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells
-
d'Adda di Fagagna F, Hande MP, Tong W-M, Roth D, Lansdorp PM, Wang Z-Q and Jackson SP (2001) Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells. Curr Biol 11: 1192-1196
-
(2001)
Curr. Biol.
, vol.11
, pp. 1192-1196
-
-
d'Adda di Fagagna, F.1
Hande, M.P.2
Tong, W.-M.3
Roth, D.4
Lansdorp, P.M.5
Wang, Z.-Q.6
Jackson, S.P.7
-
39
-
-
0035947657
-
Triplex-induced recombination in human cell-free extracts. Dependence on XPA and HsRad51
-
Datta HJ, Chan PP, Vasquez KM, Gupta RC and Glazer PM (2001) Triplex-induced recombination in human cell-free extracts. Dependence on XPA and HsRad51. J Biol Chem 276: 18018-18023
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 18018-18023
-
-
Datta, H.J.1
Chan, P.P.2
Vasquez, K.M.3
Gupta, R.C.4
Glazer, P.M.5
-
40
-
-
0026541384
-
Human telomeres are attached to the nuclear matrix
-
de Lange T (1992) Human telomeres are attached to the nuclear matrix. EMBO J 11: 717-724
-
(1992)
EMBO J.
, vol.11
, pp. 717-724
-
-
de Lange, T.1
-
41
-
-
0015924280
-
Doubling potential, calendar time, and senescence of human diploid cells in culture
-
Dell'Orco RT, Mertens JG and Kruse PF jr (1973) Doubling potential, calendar time, and senescence of human diploid cells in culture. Exp Cell Res 77: 356-360
-
(1973)
Exp. Cell Res.
, vol.77
, pp. 356-360
-
-
Dell'Orco, R.T.1
Mertens, J.G.2
Kruse Jr., P.F.3
-
42
-
-
0027466176
-
The dichotomy between germ line and somatic line, and the origin of cell mortality
-
Denis H and Lacroix J-C (1993) The dichotomy between germ line and somatic line, and the origin of cell mortality. Trends Genet 9: 7-11
-
(1993)
Trends Genet.
, vol.9
, pp. 7-11
-
-
Denis, H.1
Lacroix, J.-C.2
-
43
-
-
0033043743
-
Replication origins in metazoan chromosomes: Fact or fiction?
-
DePamphilis ML (1999) Replication origins in metazoan chromosomes: fact or fiction? BioEssays 21: 5-16
-
(1999)
BioEssays
, vol.21
, pp. 5-16
-
-
DePamphilis, M.L.1
-
45
-
-
0033595174
-
Telomere dynamics, end-to-end fusions and telomerase activation during the human fibroblast immortalization process
-
Ducray C, Pommier J-P, Martins L, Boussin FD and Sabatier L (1999) Telomere dynamics, end-to-end fusions and telomerase activation during the human fibroblast immortalization process. Oncogene 18: 4211-4223
-
(1999)
Oncogene
, vol.18
, pp. 4211-4223
-
-
Ducray, C.1
Pommier, J.-P.2
Martins, L.3
Boussin, F.D.4
Sabatier, L.5
-
47
-
-
0035313706
-
DNA-PK, ATM and ATR as sensors of DNA damage: Variations on a theme?
-
Durocher D and Jackson SP (2001) DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme? Curr Opin Cell Biol 13: 225-231
-
(2001)
Curr. Opin. Cell Biol.
, vol.13
, pp. 225-231
-
-
Durocher, D.1
Jackson, S.P.2
-
48
-
-
0032052815
-
Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids
-
Dynan WS and Yoo S (1998) Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids. Nucleic Acids Res 26: 1551-1559
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 1551-1559
-
-
Dynan, W.S.1
Yoo, S.2
-
49
-
-
0032427906
-
How might replicative senescence contribute to human ageing?
-
Faragher RGA and Kipling D (1998) How might replicative senescence contribute to human ageing? BioEssays 20: 985-991
-
(1998)
BioEssays
, vol.20
, pp. 985-991
-
-
Faragher, R.G.A.1
Kipling, D.2
-
50
-
-
0027144126
-
The gene responsible for Werner syndrome may be a cell division 'counting' gene
-
Faragher RGA, Kill IR, Hunter JAA, Pope FM, Tannock C and Shall S (1993) The gene responsible for Werner syndrome may be a cell division 'counting' gene. Proc Natl Acad Sci USA 90: 12030-12034
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 12030-12034
-
-
Faragher, R.G.A.1
Kill, I.R.2
Hunter, J.A.A.3
Pope, F.M.4
Tannock, C.5
Shall, S.6
-
51
-
-
0031585872
-
Cycling Werner's syndrome fibroblasts display calcium-dependent potassium currents
-
Faragher RGA, Hardy SP, Davis T, Dropcova S and Allen MC (1997) Cycling Werner's syndrome fibroblasts display calcium-dependent potassium currents. Exp Cell Res 231: 119-122
-
(1997)
Exp. Cell Res.
, vol.231
, pp. 119-122
-
-
Faragher, R.G.A.1
Hardy, S.P.2
Davis, T.3
Dropcova, S.4
Allen, M.C.5
-
52
-
-
0034214158
-
Telomere erosion varies during in vitro aging of normal human fibroblasts from young and adult donors
-
Figueroa R, Lindenmaier H, Hergenhahn M, Nielsen KV and Boukamp P (2000) Telomere erosion varies during in vitro aging of normal human fibroblasts from young and adult donors. Cancer Res 60: 2770-2774
-
(2000)
Cancer Res.
, vol.60
, pp. 2770-2774
-
-
Figueroa, R.1
Lindenmaier, H.2
Hergenhahn, M.3
Nielsen, K.V.4
Boukamp, P.5
-
53
-
-
0033957793
-
The yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci
-
Frei C and Gasser SM (2000) The yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci. Genes Dev 14: 81-96
-
(2000)
Genes Dev.
, vol.14
, pp. 81-96
-
-
Frei, C.1
Gasser, S.M.2
-
54
-
-
0033617316
-
Human Werner syndrome DNA helicase unwinds tetrahelical structures of the fragile X syndrome repeat sequence d(CGG)n
-
Fry M and Loeb LA (1999) Human Werner syndrome DNA helicase unwinds tetrahelical structures of the fragile X syndrome repeat sequence d(CGG)n. J Biol Chem 274: 12797-12802
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 12797-12802
-
-
Fry, M.1
Loeb, L.A.2
-
55
-
-
0017668626
-
A retarded rate of DNA replication and normal level of DNA repair in Werner's syndrome fibroblasts in culture
-
Fujiwara Y, Higashikawa T and Tatsumi M (1977) A retarded rate of DNA replication and normal level of DNA repair in Werner's syndrome fibroblasts in culture. J Cell Physiol 92: 365-374
-
(1977)
J. Cell Physiol.
, vol.92
, pp. 365-374
-
-
Fujiwara, Y.1
Higashikawa, T.2
Tatsumi, M.3
-
56
-
-
0022294216
-
Abnormal fibroblast aging and DNA replication in the Werner syndrome
-
Fujiwara Y, Kano Y, Ichihashi M, Nakao Y and Matsumura T (1985) Abnormal fibroblast aging and DNA replication in the Werner syndrome. Adv Exp Med Biol 190: 459-477
-
(1985)
Adv. Exp. Med. Biol.
, vol.190
, pp. 459-477
-
-
Fujiwara, Y.1
Kano, Y.2
Ichihashi, M.3
Nakao, Y.4
Matsumura, T.5
-
57
-
-
0028033989
-
The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: A potential eukaryotic reverse gyrase
-
Gangloff S, McDonald JP, Bendixen C, Arthur L and Rothstein R (1994) The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase. Mol Cell Biol 14: 8391-8398
-
(1994)
Mol. Cell Biol.
, vol.14
, pp. 8391-8398
-
-
Gangloff, S.1
McDonald, J.P.2
Bendixen, C.3
Arthur, L.4
Rothstein, R.5
-
58
-
-
0016313121
-
Senescence of cultured human fibroblasts: Mitotic versus metabolic time
-
Goldstein S and Singal DP (1974) Senescence of cultured human fibroblasts: mitotic versus metabolic time. Exp Cell Res 88: 359-364
-
(1974)
Exp. Cell Res.
, vol.88
, pp. 359-364
-
-
Goldstein, S.1
Singal, D.P.2
-
59
-
-
0035341813
-
p53 and PML: New partners in tumor suppression
-
Gottifredi V and Prives C (2001) p53 and PML: new partners in tumor suppression. Trends Cell Biol 11: 184-187
-
(2001)
Trends Cell Biol.
, vol.11
, pp. 184-187
-
-
Gottifredi, V.1
Prives, C.2
-
60
-
-
0030751354
-
The Werner syndrome protein is a DNA helicase
-
Gray MD, Shen J-C, Kamath-Loeb AS, Blank A, Sopher BL, Martin GM, Oshima J and Loeb LA (1997) The Werner syndrome protein is a DNA helicase. Nat Genet 17: 100-103
-
(1997)
Nat. Genet.
, vol.17
, pp. 100-103
-
-
Gray, M.D.1
Shen, J.-C.2
Kamath-Loeb, A.S.3
Blank, A.4
Sopher, B.L.5
Martin, G.M.6
Oshima, J.7
Loeb, L.A.8
-
61
-
-
0032146147
-
Werner helicase is localized to transcriptionally active nucleoli of cycling cells
-
Gray MD, Wang L, Youssoufian H, Martin GM and Oshima J (1998) Werner helicase is localized to transcriptionally active nucleoli of cycling cells. Exp Cell Res 242: 487-494
-
(1998)
Exp. Cell Res.
, vol.242
, pp. 487-494
-
-
Gray, M.D.1
Wang, L.2
Youssoufian, H.3
Martin, G.M.4
Oshima, J.5
-
62
-
-
0032567975
-
Telomeres and senescence: The history, the experiment, the future
-
Greider CW (1998) Telomeres and senescence: the history, the experiment, the future. Curr Biol 8: R178-R181
-
(1998)
Curr. Biol.
, vol.8
-
-
Greider, C.W.1
-
63
-
-
0032562649
-
TRF1 promotes parallel pairing of telomeric tracts in vitro
-
Griffith J, Bianchi A and de Lange T (1998) TRF1 promotes parallel pairing of telomeric tracts in vitro. J Mol Biol 278: 79-88
-
(1998)
J. Mol. Biol.
, vol.278
, pp. 79-88
-
-
Griffith, J.1
Bianchi, A.2
de Lange, T.3
-
64
-
-
0033553536
-
Mammalian telomeres end in a large duplex loop
-
Griffith JD, Comeau L, Rosenfield S, Stansel RM, Bianchi A, Moss H and de Lange T (1999) Mammalian telomeres end in a large duplex loop. Cell 97: 503-514
-
(1999)
Cell
, vol.97
, pp. 503-514
-
-
Griffith, J.D.1
Comeau, L.2
Rosenfield, S.3
Stansel, R.M.4
Bianchi, A.5
Moss, H.6
de Lange, T.7
-
65
-
-
0034503110
-
ALT-associated PML bodies are present in viable cells and are enriched in cells in the G2/M phase of the cell cycle
-
Grobelny JV, Godwin AK and Broccoli D (2000) ALT-associated PML bodies are present in viable cells and are enriched in cells in the G2/M phase of the cell cycle. J Cell Sci 113: 4577-4585
-
(2000)
J. Cell Sci.
, vol.113
, pp. 4577-4585
-
-
Grobelny, J.V.1
Godwin, A.K.2
Broccoli, D.3
-
66
-
-
0032030493
-
One cell, two cell, red cell, blue cell: The persistence of a unicellular stage in multicellular life histories
-
Grosberg RK and Strathmann RR (1998) One cell, two cell, red cell, blue cell: the persistence of a unicellular stage in multicellular life histories. Trends Ecol Evol 13: 112-116
-
(1998)
Trends Ecol. Evol.
, vol.13
, pp. 112-116
-
-
Grosberg, R.K.1
Strathmann, R.R.2
-
67
-
-
0034106727
-
Recombination: A frank view of exchanges and vice versa
-
Haber JE (2000) Recombination: a frank view of exchanges and vice versa. Curr Opin Cell Biol 12: 286-292
-
(2000)
Curr. Opin. Cell Biol.
, vol.12
, pp. 286-292
-
-
Haber, J.E.1
-
68
-
-
0025279931
-
Telomeres shorten during ageing of human fibroblasts
-
Harley CB, Futcher AB and Greider CW (1990) Telomeres shorten during ageing of human fibroblasts. Nature 345: 458-460
-
(1990)
Nature
, vol.345
, pp. 458-460
-
-
Harley, C.B.1
Futcher, A.B.2
Greider, C.W.3
-
69
-
-
0032522789
-
RecQ helicase, in concert with RecA and SSB proteins, initiates and disrupts DNA recombination
-
Harmon FG and Kowalczykowski SC (1998) RecQ helicase, in concert with RecA and SSB proteins, initiates and disrupts DNA recombination. Genes Dev 12: 1134-1144
-
(1998)
Genes Dev.
, vol.12
, pp. 1134-1144
-
-
Harmon, F.G.1
Kowalczykowski, S.C.2
-
70
-
-
0035812845
-
The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability
-
Hemann MT, Strong MA, Hao L-Y and Greider CW (2001) The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability. Cell 107: 67-77
-
(2001)
Cell
, vol.107
, pp. 67-77
-
-
Hemann, M.T.1
Strong, M.A.2
Hao, L.-Y.3
Greider, C.W.4
-
71
-
-
0030006735
-
In situ analysis of changes in telomere size during replicative aging and cell transformation
-
Henderson S, Allsopp R, Spector D, Wang S-S and Harley C (1996) In situ analysis of changes in telomere size during replicative aging and cell transformation. J Cell Biol 134: 1-12
-
(1996)
J. Cell Biol.
, vol.134
, pp. 1-12
-
-
Henderson, S.1
Allsopp, R.2
Spector, D.3
Wang, S.-S.4
Harley, C.5
-
73
-
-
0034192355
-
WRN or telomerase constructs reverse 4-nitroquinoline 1-oxide sensitivity in transformed Werner syndrome fibroblasts
-
Hisama FM, Chen Y-H, Meyn MS, Oshima J and Weissman SM (2000) WRN or telomerase constructs reverse 4-nitroquinoline 1-oxide sensitivity in transformed Werner syndrome fibroblasts. Cancer Res 60: 2372-2376
-
(2000)
Cancer Res.
, vol.60
, pp. 2372-2376
-
-
Hisama, F.M.1
Chen, Y.-H.2
Meyn, M.S.3
Oshima, J.4
Weissman, S.M.5
-
74
-
-
0015496897
-
Altered enzymes in ageing human fibroblasts
-
Holliday R and Tarrant GM (1972) Altered enzymes in ageing human fibroblasts. Nature 238: 26-30
-
(1972)
Nature
, vol.238
, pp. 26-30
-
-
Holliday, R.1
Tarrant, G.M.2
-
75
-
-
0033525095
-
Double-strand break repair in yeast requires both leading and lagging strand DNA polymerases
-
Holmes AM and Haber JE (1999) Double-strand break repair in yeast requires both leading and lagging strand DNA polymerases. Cell 96: 415-424
-
(1999)
Cell
, vol.96
, pp. 415-424
-
-
Holmes, A.M.1
Haber, J.E.2
-
76
-
-
0027311843
-
Visualization of replication factories attached to a nucleoskeleton
-
Hozak P, Hassan AB, Jackson DA and Cook PR (1993) Visualization of replication factories attached to a nucleoskeleton. Cell 73: 361-373
-
(1993)
Cell
, vol.73
, pp. 361-373
-
-
Hozak, P.1
Hassan, A.B.2
Jackson, D.A.3
Cook, P.R.4
-
77
-
-
0031686571
-
The premature ageing syndrome protein, WRN, is a 3′-5′ exonuclease
-
Huang S, Li B, Gray MD, Oshima J, Mian IS and Campisi J (1998) The premature ageing syndrome protein, WRN, is a 3′-5′ exonuclease. Nat Genet 20: 114-116
-
(1998)
Nat. Genet.
, vol.20
, pp. 114-116
-
-
Huang, S.1
Li, B.2
Gray, M.D.3
Oshima, J.4
Mian, I.S.5
Campisi, J.6
-
78
-
-
0034660246
-
Characterization of the human and mouse WRN 3′-5′ exonuclease
-
Huang S, Beresten S, Li B, Oshima J, Ellis NA and Campisi J (2000) Characterization of the human and mouse WRN 3′-5′ exonuclease. Nucleic Acids Res 28: 2396-2405
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 2396-2405
-
-
Huang, S.1
Beresten, S.2
Li, B.3
Oshima, J.4
Ellis, N.A.5
Campisi, J.6
-
79
-
-
0035936559
-
SGS1 is required for telomere elongation in the absence of telomerase
-
Huang P-H, Pryde FE, Lester D, Maddison RL, Borts RH, Hickson ID and Louis EJ (2001) SGS1 is required for telomere elongation in the absence of telomerase. Curr Biol 11: 125-129
-
(2001)
Curr. Biol.
, vol.11
, pp. 125-129
-
-
Huang, P.-H.1
Pryde, F.E.2
Lester, D.3
Maddison, R.L.4
Borts, R.H.5
Hickson, I.D.6
Louis, E.J.7
-
80
-
-
0030826334
-
Ubc9p is the conjugating enzyme for the ubiquitin-like protein Smt3p
-
Johnson ES and Blobel G (1997) Ubc9p is the conjugating enzyme for the ubiquitin-like protein Smt3p. J Biol Chem 272: 26799-26802
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 26799-26802
-
-
Johnson, E.S.1
Blobel, G.2
-
81
-
-
0035865143
-
The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase
-
Johnson FB, Marciniak RA, McVey M, Stewart SA, Hahn WC and Guarente L (2001) The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase. EMBO J 20: 905-913
-
(2001)
EMBO J.
, vol.20
, pp. 905-913
-
-
Johnson, F.B.1
Marciniak, R.A.2
McVey, M.3
Stewart, S.A.4
Hahn, W.C.5
Guarente, L.6
-
82
-
-
0021999880
-
Intramitotic variation in proliferative potential: Stochastic events in celullar aging
-
Jones RB, Whitney RG and Smith JR (1985) Intramitotic variation in proliferative potential: stochastic events in celullar aging. Mech Ageing Dev 29: 143-149
-
(1985)
Mech. Ageing Dev.
, vol.29
, pp. 143-149
-
-
Jones, R.B.1
Whitney, R.G.2
Smith, J.R.3
-
83
-
-
0032545423
-
Werner syndrome protein. II. Characterization of the integral 3′-5′ DNA exonuclease
-
Kamath-Loeb AS, Shen J-C, Loeb LA and Fry M (1998) Werner syndrome protein. II. Characterization of the integral 3′-5′ DNA exonuclease. J Biol Chem 273: 34145-34150
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 34145-34150
-
-
Kamath-Loeb, A.S.1
Shen, J.-C.2
Loeb, L.A.3
Fry, M.4
-
85
-
-
0035844242
-
Interactions between the Werner syndrome helicase and DNA polymerase δ specifically facilitate copying of tetraplex and hairpin structures of the d(CGG)n trinucleotide repeat sequence
-
Kamath-Loeb AS, Loeb LA, Johansson E, Burgers PMJ and Fry M (2001) Interactions between the Werner syndrome helicase and DNA polymerase δ specifically facilitate copying of tetraplex and hairpin structures of the d(CGG)n trinucleotide repeat sequence. J Biol Chem 276: 16439-16446
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 16439-16446
-
-
Kamath-Loeb, A.S.1
Loeb, L.A.2
Johansson, E.3
Burgers, P.M.J.4
Fry, M.5
-
86
-
-
0037166306
-
Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation
-
Karmakar P, Piotrowski J, Brosh RM jr, Sommers JA, Lees Miller SP, Cheng W-H, Snowden CM, Ramsden DA and Bohr VA (2002) Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation. J Biol Chem 277: 18291-18302
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 18291-18302
-
-
Karmakar, P.1
Piotrowski, J.2
Brosh Jr., R.M.3
Sommers, J.A.4
Lees Miller, S.P.5
Cheng, W.-H.6
Snowden, C.M.7
Ramsden, D.A.8
Bohr, V.A.9
-
87
-
-
0034647556
-
Covalent modification of the Werner's syndrome gene product with the ubiquitin-related protein, SUMO-1
-
Kawabe Y-i, Seki M, Seki T, Wang W-S, Imamura O, Furuichi Y, Saitoh H and Enomoto T (2000) Covalent modification of the Werner's syndrome gene product with the ubiquitin-related protein, SUMO-1. J Biol Chem 275: 20963-20966
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 20963-20966
-
-
Kawabe, Y.-I.1
Seki, M.2
Seki, T.3
Wang, W.-S.4
Imamura, O.5
Furuichi, Y.6
Saitoh, H.7
Enomoto, T.8
-
88
-
-
0035827598
-
A novel protein interacts with the Werner's syndrome gene product physically and functionally
-
Kawabe Y-i, Branzei D, Hayashi T, Suzuki H, Masuko T, Onoda F, Heo S-J, Ikeda H, Shimamoto A, Furuichi Y, Seki M and Enomoto T (2001) A novel protein interacts with the Werner's syndrome gene product physically and functionally. J Biol Chem 276: 20364-20369
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 20364-20369
-
-
Kawabe, Y.-I.1
Branzei, D.2
Hayashi, T.3
Suzuki, H.4
Masuko, T.5
Onoda, F.6
Heo, S.-J.7
Ikeda, H.8
Shimamoto, A.9
Furuichi, Y.10
Seki, M.11
Enomoto, T.12
-
89
-
-
0028295472
-
The expression of proliferation-dependent antigens during the lifespan of normal and progeroid human fibroblasts in culture
-
Kill IR, Faragher RGA, Lawrence K and Shall S (1994) The expression of proliferation-dependent antigens during the lifespan of normal and progeroid human fibroblasts in culture. J Cell Sci 107: 571-579
-
(1994)
J. Cell Sci.
, vol.107
, pp. 571-579
-
-
Kill, I.R.1
Faragher, R.G.A.2
Lawrence, K.3
Shall, S.4
-
90
-
-
85069126779
-
Telomere-dependent senescence
-
Kipling D, Wynford-Thomas D, Jones CJ, Akbar A, Aspinall R, Bacchetti S, Blasco MA, Broccoli D, DePinho RA, Edwards DR, Effros RB, Harley CB, Lansdorp PM, Linskens MHK, Prowse KR, Newbold RF, Olovnikov AM, Parkinson EK, Pawelec G, Ponten J, Shall S, Zijlmans M and Faragher RGA (1999) Telomere-dependent senescence. Nat Biotech 17: 313
-
(1999)
Nat. Biotech.
, vol.17
, pp. 313
-
-
Kipling, D.1
Wynford-Thomas, D.2
Jones, C.J.3
Akbar, A.4
Aspinall, R.5
Bacchetti, S.6
Blasco, M.A.7
Broccoli, D.8
DePinho, R.A.9
Edwards, D.R.10
Effros, R.B.11
Harley, C.B.12
Lansdorp, P.M.13
Linskens, M.H.K.14
Prowse, K.R.15
Newbold, R.F.16
Olovnikov, A.M.17
Parkinson, E.K.18
Pawelec, G.19
Ponten, J.20
Shall, S.21
Zijlmans, M.22
Faragher, R.G.A.23
more..
-
91
-
-
0022546892
-
Formation of 8-hydroxyguanine residues in cellular DNA exposed to the carcinogen 4-nitroquinoline 1-oxide
-
Kohda K, Tada M, Kasai H, Nishimura S and Kawazoe Y (1986) Formation of 8-hydroxyguanine residues in cellular DNA exposed to the carcinogen 4-nitroquinoline 1-oxide. Biochem Biophys Res Commun 139: 626-632
-
(1986)
Biochem. Biophys. Res. Commun.
, vol.139
, pp. 626-632
-
-
Kohda, K.1
Tada, M.2
Kasai, H.3
Nishimura, S.4
Kawazoe, Y.5
-
92
-
-
0031927120
-
Improved detection and comparative sizing of human chromosomal telomeres in situ
-
Krejci K and Koch J (1998) Improved detection and comparative sizing of human chromosomal telomeres in situ. Chromosoma 107: 198-203
-
(1998)
Chromosoma
, vol.107
, pp. 198-203
-
-
Krejci, K.1
Koch, J.2
-
93
-
-
0033152108
-
An in situ study of variant telomeric repeats in human chromosomes
-
Krejci K and Koch J (1999) An in situ study of variant telomeric repeats in human chromosomes. Genomics 58: 202-206
-
(1999)
Genomics
, vol.58
, pp. 202-206
-
-
Krejci, K.1
Koch, J.2
-
94
-
-
0033621354
-
The Werner syndrome gene product co-purifies with the DNA replication complex and interacts with PCNA and topoisomerase I
-
Lebel M, Spillare EA, Harris CC and Leder P (1999) The Werner syndrome gene product co-purifies with the DNA replication complex and interacts with PCNA and topoisomerase I. J Biol Chem 274: 37795-37799
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37795-37799
-
-
Lebel, M.1
Spillare, E.A.2
Harris, C.C.3
Leder, P.4
-
95
-
-
0026735646
-
Telomere end-replication problem and cell aging
-
Levy MZ, Allsopp RC, Futcher AB, Greider CW and Harley CB (1992) Telomere end-replication problem and cell aging. J Mol Biol 225: 951-960
-
(1992)
J. Mol. Biol.
, vol.225
, pp. 951-960
-
-
Levy, M.Z.1
Allsopp, R.C.2
Futcher, A.B.3
Greider, C.W.4
Harley, C.B.5
-
96
-
-
0034665971
-
Functional interaction between Ku and the Werner syndrome protein in DNA end processing
-
Li B and Comai L (2000) Functional interaction between Ku and the Werner syndrome protein in DNA end processing. J Biol Chem 275: 28349-28352
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 28349-28352
-
-
Li, B.1
Comai, L.2
-
97
-
-
0035909817
-
Inhibition of the Bloom's and Werner's syndrome helicases by G-quadruplex interacting ligands
-
Li J-L, Harrison RJ, Reszka AP, Brosh RM jr, Bohr VA, Neidle S and Hickson ID (2001) Inhibition of the Bloom's and Werner's syndrome helicases by G-quadruplex interacting ligands. Biochemistry 40: 15194-15202
-
(2001)
Biochemistry
, vol.40
, pp. 15194-15202
-
-
Li, J.-L.1
Harrison, R.J.2
Reszka, A.P.3
Brosh Jr., R.M.4
Bohr, V.A.5
Neidle, S.6
Hickson, I.D.7
-
98
-
-
0036714151
-
Displacement of DNA-PKcs from DNA ends by the Werner syndrome protein
-
Li B and Comai L (2002) Displacement of DNA-PKcs from DNA ends by the Werner syndrome protein. Nucleic Acids Res 30: 3653-3661
-
(2002)
Nucleic Acids Res.
, vol.30
, pp. 3653-3661
-
-
Li, B.1
Comai, L.2
-
100
-
-
0031104841
-
The FEN-1 family of structure-specific nucleases in eukaryotic DNA replication, recombination and repair
-
Lieber MR (1997) The FEN-1 family of structure-specific nucleases in eukaryotic DNA replication, recombination and repair. BioEssays 19: 233-240
-
(1997)
BioEssays
, vol.19
, pp. 233-240
-
-
Lieber, M.R.1
-
102
-
-
0037040228
-
DNase I footprinting and enhanced exonuclease function of the bipartite Werner syndrome protein (WRN) bound to partially melted duplex DNA
-
Machwe A, Xiao L, Theodore S and Orren DK (2002) DNase I footprinting and enhanced exonuclease function of the bipartite Werner syndrome protein (WRN) bound to partially melted duplex DNA. J Biol Chem 277: 4492-4504
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 4492-4504
-
-
Machwe, A.1
Xiao, L.2
Theodore, S.3
Orren, D.K.4
-
103
-
-
0032445201
-
The time-pattern of rises and falls in proliferation fades with senescence of mortal lines and is perpetuated in immortal rat hepatoma FAO cell line
-
Maigne J, Deschatrette J, Sarrazin S, Hecquet B, Guerroui S and Wolfrom C (1998) The time-pattern of rises and falls in proliferation fades with senescence of mortal lines and is perpetuated in immortal rat hepatoma FAO cell line. In Vitro Cell Dev Biol A 34: 163-169
-
(1998)
In Vitro Cell Dev. Biol. A
, vol.34
, pp. 163-169
-
-
Maigne, J.1
Deschatrette, J.2
Sarrazin, S.3
Hecquet, B.4
Guerroui, S.5
Wolfrom, C.6
-
105
-
-
0031984598
-
Short telomeres on human chromosome 17p
-
Martens UM, Zijlmans JMJM, Poon SSS, Dragowska W, Yui J, Chavez EA, Ward RK and Lansdorp PM (1998) Short telomeres on human chromosome 17p. Nat Genet 18: 76-80
-
(1998)
Nat. Genet.
, vol.18
, pp. 76-80
-
-
Martens, U.M.1
Zijlmans, J.M.J.M.2
Poon, S.S.S.3
Dragowska, W.4
Yui, J.5
Chavez, E.A.6
Ward, R.K.7
Lansdorp, P.M.8
-
106
-
-
0034630432
-
Accumulation of short telomeres in human fibroblasts prior to replicative senescence
-
Martens UM, Chavez EA, Poon SSS, Schmoor C and Lansdorp PM (2000) Accumulation of short telomeres in human fibroblasts prior to replicative senescence. Exp Cell Res 256: 291-299
-
(2000)
Exp. Cell Res.
, vol.256
, pp. 291-299
-
-
Martens, U.M.1
Chavez, E.A.2
Poon, S.S.S.3
Schmoor, C.4
Lansdorp, P.M.5
-
108
-
-
0015966119
-
Clonal selection, attenuation and differentiation in an in vitro model of hyperplasia
-
Martin GM, Sprague CA, Norwood TH and Pendergrass WR (1974) Clonal selection, attenuation and differentiation in an in vitro model of hyperplasia. Am J Pathol 74: 137-154
-
(1974)
Am. J. Pathol.
, vol.74
, pp. 137-154
-
-
Martin, G.M.1
Sprague, C.A.2
Norwood, T.H.3
Pendergrass, W.R.4
-
109
-
-
0002134284
-
Old age and natural death
-
(new series) Reprinted in Medawar PB (1957) The Uniqueness of the Individual. Methuen, London, UK
-
Medawar PB (1946) Old age and natural death. Mod Quart 2 (new series): 30-49. Reprinted in Medawar PB (1957) The Uniqueness of the Individual. Methuen, London, UK
-
(1946)
Mod. Quart.
, vol.2
, pp. 30-49
-
-
Medawar, P.B.1
-
110
-
-
0024460266
-
In vitro DNA modification by the ultimate carcinogen of 4-nitroquinoline-1-oxide: Influence of superhelicity
-
Menichini P, Fronza G, Tornaletti S, Galiegue-Zouitina S, Bailleul B, Loucheux-Lefebvre M-H, Abbondandolo A and Pedrini AM (1989) In vitro DNA modification by the ultimate carcinogen of 4-nitroquinoline-1-oxide: influence of superhelicity. Carcinogenesis 10: 1589-1593
-
(1989)
Carcinogenesis
, vol.10
, pp. 1589-1593
-
-
Menichini, P.1
Fronza, G.2
Tornaletti, S.3
Galiegue-Zouitina, S.4
Bailleul, B.5
Loucheux-Lefebvre, M.-H.6
Abbondandolo, A.7
Pedrini, A.M.8
-
111
-
-
0017052939
-
Characterization of fractionated human diploid fibroblast cell populations
-
Mitsui Y and Schneider EL (1976) Characterization of fractionated human diploid fibroblast cell populations. Exp Cell Res 103: 23-30
-
(1976)
Exp. Cell Res.
, vol.103
, pp. 23-30
-
-
Mitsui, Y.1
Schneider, E.L.2
-
112
-
-
0035393720
-
The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases
-
Mohaghegh P, Karow JK, Brosh RM jr, Bohr VA and Hickson ID (2001) The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases. Nucleic Acids Res 29: 2843-2849
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 2843-2849
-
-
Mohaghegh, P.1
Karow, J.K.2
Brosh Jr., R.M.3
Bohr, V.A.4
Hickson, I.D.5
-
115
-
-
0016912063
-
Molecular biology of the carcinogen, 4-nitroquinoline 1-oxide
-
Nagao M and Sugimura T (1976) Molecular biology of the carcinogen, 4-nitroquinoline 1-oxide. Adv Cancer Res 23: 131-169
-
(1976)
Adv. Cancer Res.
, vol.23
, pp. 131-169
-
-
Nagao, M.1
Sugimura, T.2
-
116
-
-
0035130130
-
Telomere associations in interphase nuclei: Possible role in maintenance of interphase chromosome topology
-
Nagele RG, Velasco AQ, Anderson WJ, McMahon DJ, Thomson Z, Fazekas J, Wind K and Lee H-y (2001) Telomere associations in interphase nuclei: possible role in maintenance of interphase chromosome topology. J Cell Sci 114: 377-388
-
(2001)
J. Cell Sci.
, vol.114
, pp. 377-388
-
-
Nagele, R.G.1
Velasco, A.Q.2
Anderson, W.J.3
McMahon, D.J.4
Thomson, Z.5
Fazekas, J.6
Wind, K.7
Lee, H.-Y.8
-
117
-
-
0029892697
-
Organization of DNA into foci during replication
-
Newport J and Yan H (1996) Organization of DNA into foci during replication. Curr Opin Cell Biol 8: 365-368
-
(1996)
Curr. Opin. Cell Biol.
, vol.8
, pp. 365-368
-
-
Newport, J.1
Yan, H.2
-
119
-
-
0027319211
-
Potent intracellular oxidative stress exerted by the carcinogen 4-nitroquinoline-N-oxide
-
Nunoshiba T and Demple B (1993) Potent intracellular oxidative stress exerted by the carcinogen 4-nitroquinoline-N-oxide. Cancer Res 53: 3250-3252
-
(1993)
Cancer Res.
, vol.53
, pp. 3250-3252
-
-
Nunoshiba, T.1
Demple, B.2
-
120
-
-
0034666241
-
Telomere repeat DNA forms a large non-covalent complex with unique cohesive properties which is dissociated by Werner syndrome DNA helicase in the presence of replication protein A
-
Ohsugi I, Tokutake Y, Suzuki N, Ide T, Sugimoto M and Furuichi Y (2000) Telomere repeat DNA forms a large non-covalent complex with unique cohesive properties which is dissociated by Werner syndrome DNA helicase in the presence of replication protein A. Nucleic Acids Res 28: 3642-3648
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 3642-3648
-
-
Ohsugi, I.1
Tokutake, Y.2
Suzuki, N.3
Ide, T.4
Sugimoto, M.5
Furuichi, Y.6
-
121
-
-
0035976963
-
Coordinate action of the helicase and 3′ to 5′ exonuclease of Werner syndrome protein
-
Opresko PL, Laine J-P, Brosh RM jr, Seidman MM and Bohr VA (2001) Coordinate action of the helicase and 3′ to 5′ exonuclease of Werner syndrome protein. J Biol Chem 276: 44677-44687
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 44677-44687
-
-
Opresko, P.L.1
Laine, J.-P.2
Brosh Jr., R.M.3
Seidman, M.M.4
Bohr, V.A.5
-
122
-
-
0037175018
-
Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases
-
Opresko PL, von Kobbe C, Laine J-P, Harrigan J, Hickson ID and Bohr VA (2002) Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases. J Biol Chem 277: 41110-41119
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 41110-41119
-
-
Opresko, P.L.1
von Kobbe, C.2
Laine, J.-P.3
Harrigan, J.4
Hickson, I.D.5
Bohr, V.A.6
-
123
-
-
0033199454
-
Enzymatic and DNA binding properties of purified WRN protein: High affinity binding to single-stranded DNA but not to DNA damage induced by 4NQO
-
Orren DK, Brosh RM jr, Nehlin JO, Machwe A, Gray MD and Bohr VA (1999) Enzymatic and DNA binding properties of purified WRN protein: high affinity binding to single-stranded DNA but not to DNA damage induced by 4NQO. Nucleic Acids Res 27: 3557-3566
-
(1999)
Nucleic Acids Res.
, vol.27
, pp. 3557-3566
-
-
Orren, D.K.1
Brosh Jr., R.M.2
Nehlin, J.O.3
Machwe, A.4
Gray, M.D.5
Bohr, V.A.6
-
124
-
-
0035339672
-
A functional interaction of Ku with Werner exonuclease facilitates digestion of damaged DNA
-
Orren DK, Machwe A, Karmakar P, Piotrowski J, Cooper MP and Bohr VA (2001) A functional interaction of Ku with Werner exonuclease facilitates digestion of damaged DNA. Nucleic Acids Res 29: 1926-1934
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 1926-1934
-
-
Orren, D.K.1
Machwe, A.2
Karmakar, P.3
Piotrowski, J.4
Cooper, M.P.5
Bohr, V.A.6
-
125
-
-
0037137177
-
The Werner syndrome helicase/exonuclease (WRN) disrupts and degrades D-loops in vitro
-
Orren DK, Theodore S and Machwe A (2002) The Werner syndrome helicase/exonuclease (WRN) disrupts and degrades D-loops in vitro. Biochemistry 41: 13483-13488
-
(2002)
Biochemistry
, vol.41
, pp. 13483-13488
-
-
Orren, D.K.1
Theodore, S.2
Machwe, A.3
-
126
-
-
0033771208
-
The Werner syndrome protein: An update
-
Oshima J (2000) The Werner syndrome protein: an update. BioEssays 22: 894-901
-
(2000)
BioEssays
, vol.22
, pp. 894-901
-
-
Oshima, J.1
-
127
-
-
0018858066
-
A fixed site of DNA replication in eucaryotic cells
-
Pardoll DM, Vogelstein B and Coffey DS (1980) A fixed site of DNA replication in eucaryotic cells. Cell 19: 527-536
-
(1980)
Cell
, vol.19
, pp. 527-536
-
-
Pardoll, D.M.1
Vogelstein, B.2
Coffey, D.S.3
-
128
-
-
0032974345
-
Accumulation of single-stranded DNA and destabilization of telomeric repeats in yeast mutant strains carrying a deletion of RAD27
-
Parenteau J and Wellinger RJ (1999) Accumulation of single-stranded DNA and destabilization of telomeric repeats in yeast mutant strains carrying a deletion of RAD27. Mol Cell Biol 19: 4143-4152
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 4143-4152
-
-
Parenteau, J.1
Wellinger, R.J.2
-
129
-
-
0037142071
-
Crystal structure of parallel quadruplexes from human telomeric DNA
-
Parkinson GN, Lee MPH and Neidle S (2002) Crystal structure of parallel quadruplexes from human telomeric DNA. Nature 417: 876-880
-
(2002)
Nature
, vol.417
, pp. 876-880
-
-
Parkinson, G.N.1
Lee, M.P.H.2
Neidle, S.3
-
130
-
-
0033975907
-
In vitro senescence models for human T lymphocytes
-
Pawelec G, Adibzadeh M, Rehbein A, Hahnel K, Wagner W and Engel A (2000) In vitro senescence models for human T lymphocytes. Vaccine 18: 1666-1674
-
(2000)
Vaccine
, vol.18
, pp. 1666-1674
-
-
Pawelec, G.1
Adibzadeh, M.2
Rehbein, A.3
Hahnel, K.4
Wagner, W.5
Engel, A.6
-
131
-
-
0035169035
-
Werner's syndrome protein is required for correct recovery after replication arrest and DNA damage induced in S-phase of cell cycle
-
Pichierri P, Franchitto A, Mosesso P and Palitti F (2001) Werner's syndrome protein is required for correct recovery after replication arrest and DNA damage induced in S-phase of cell cycle. Mol Biol Cell 12: 2412-2421
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 2412-2421
-
-
Pichierri, P.1
Franchitto, A.2
Mosesso, P.3
Palitti, F.4
-
132
-
-
0028335752
-
Alterations in contact and density-dependent arrest state in senescent WI-38 cells
-
Pignolo RJ, Rotenberg MO and Cristofalo VJ (1994) Alterations in contact and density-dependent arrest state in senescent WI-38 cells. In vitro Cell Dev Biol A 30: 471-476
-
(1994)
In Vitro Cell Dev. Biol. A
, vol.30
, pp. 471-476
-
-
Pignolo, R.J.1
Rotenberg, M.O.2
Cristofalo, V.J.3
-
133
-
-
0032808411
-
Cell fusion corrects the 4-nitroquinoline 1-oxide sensitivity of Werner syndrome fibroblast cell lines
-
Prince PR, Ogburn CE, Moser MJ, Emond MJ, Martin GM and Monnat RJ jr (1999) Cell fusion corrects the 4-nitroquinoline 1-oxide sensitivity of Werner syndrome fibroblast cell lines. Hum Genet 105: 132-138
-
(1999)
Hum. Genet.
, vol.105
, pp. 132-138
-
-
Prince, P.R.1
Ogburn, C.E.2
Moser, M.J.3
Emond, M.J.4
Martin, G.M.5
Monnat Jr., R.J.6
-
134
-
-
84873770071
-
Clonal growth in vitro of human cells with fibroblastic morphology. Comparison of growth and genetic characteristics of single epithelioid and fibroblast-like cells from a variety of human organs
-
Puck TT, Cieciura SJ and Fischer HW (1957) Clonal growth in vitro of human cells with fibroblastic morphology. Comparison of growth and genetic characteristics of single epithelioid and fibroblast-like cells from a variety of human organs. J Exp Med 106: 145-158
-
(1957)
J. Exp. Med.
, vol.106
, pp. 145-158
-
-
Puck, T.T.1
Cieciura, S.J.2
Fischer, H.W.3
-
135
-
-
84873782420
-
Genetics of somatic mammalian cells. III. Long-term cultivation of cells from human and animal subjects
-
Puck TT, Cieciura SJ and Robinson A (1958) Genetics of somatic mammalian cells. III. Long-term cultivation of cells from human and animal subjects. J Exp Med 108: 945-956
-
(1958)
J. Exp. Med.
, vol.108
, pp. 945-956
-
-
Puck, T.T.1
Cieciura, S.J.2
Robinson, A.3
-
136
-
-
0027937691
-
Speculation on the biological roles of left-handed Z-DNA
-
Rich A (1994) Speculation on the biological roles of left-handed Z-DNA. Ann N Y Acad Sci 726: 1-16
-
(1994)
Ann. N. Y. Acad. Sci.
, vol.726
, pp. 1-16
-
-
Rich, A.1
-
137
-
-
0028298247
-
The ultimate carcinogen of 4-nitroquinoline 1-oxide does not react with Z-DNA and hyperreacts with B-Z junctions
-
Rodolfo C, Lanza A, Tomaletti S, Fronza G and Pedrini AM (1994) The ultimate carcinogen of 4-nitroquinoline 1-oxide does not react with Z-DNA and hyperreacts with B-Z junctions. Nucleic Acids Res 22: 314-320
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 314-320
-
-
Rodolfo, C.1
Lanza, A.2
Tomaletti, S.3
Fronza, G.4
Pedrini, A.M.5
-
138
-
-
0035009356
-
Werner helicase relocates into nuclear foci in response to DNA damaging agents and co-localizes with RPA and Rad51
-
Sakamoto S, Nishikawa K, Heo SJ, Goto M, Furuichi Y and Shimamoto A (2001) Werner helicase relocates into nuclear foci in response to DNA damaging agents and co-localizes with RPA and Rad51. Genes Cells 6: 421-430
-
(2001)
Genes Cells
, vol.6
, pp. 421-430
-
-
Sakamoto, S.1
Nishikawa, K.2
Heo, S.J.3
Goto, M.4
Furuichi, Y.5
Shimamoto, A.6
-
139
-
-
0019444282
-
Systematic growth studies, cocultivation, and cell hybridization studies of Werner syndrome cultured skin fibroblasts
-
Salk D, Bryant E, Au K, Hoehn H and Martin GM (1981a) Systematic growth studies, cocultivation, and cell hybridization studies of Werner syndrome cultured skin fibroblasts. Hum Genet 58: 310-316
-
(1981)
Hum. Genet.
, vol.58
, pp. 310-316
-
-
Salk, D.1
Bryant, E.2
Au, K.3
Hoehn, H.4
Martin, G.M.5
-
140
-
-
0019449447
-
Evidence of clonal attenuation, clonal succession, and clonal expansion in mass cultures of aging Werner's syndrome skin fibroblasts
-
Salk D, Au K, Hoehn H, Stenchever MR and Martin GM (1981b) Evidence of clonal attenuation, clonal succession, and clonal expansion in mass cultures of aging Werner's syndrome skin fibroblasts. Cytogenet Cell Genet 30: 108-117
-
(1981)
Cytogenet. Cell Genet.
, vol.30
, pp. 108-117
-
-
Salk, D.1
Au, K.2
Hoehn, H.3
Stenchever, M.R.4
Martin, G.M.5
-
141
-
-
0036325423
-
Telomere lengthening in telomerase-negative cells: The ends are coming together
-
Scheel C and Poremba C (2002) Telomere lengthening in telomerase-negative cells: the ends are coming together. Virchows Arch 440: 573-582
-
(2002)
Virchows Arch.
, vol.440
, pp. 573-582
-
-
Scheel, C.1
Poremba, C.2
-
142
-
-
0029971241
-
Accelerated loss of telomeric repeats may not explain accelerated replicative decline of Werner syndrome cells
-
Schulz VP, Zakian VA, Ogburn CE, McKay J, Jarzebowicz AA, Edland SD and Martin GM (1996) Accelerated loss of telomeric repeats may not explain accelerated replicative decline of Werner syndrome cells. Hum Genet 97: 750-754
-
(1996)
Hum. Genet.
, vol.97
, pp. 750-754
-
-
Schulz, V.P.1
Zakian, V.A.2
Ogburn, C.E.3
McKay, J.4
Jarzebowicz, A.A.5
Edland, S.D.6
Martin, G.M.7
-
143
-
-
0032526583
-
Characterization of Werner syndrome protein DNA helicase activity: Directionality, substrate dependence and stimulation by replication protein A
-
Shen J-C, Gray MD, Oshima J and Loeb LA (1998a) Characterization of Werner syndrome protein DNA helicase activity: directionality, substrate dependence and stimulation by replication protein A. Nucleic Acids Res 26: 2879-2885
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 2879-2885
-
-
Shen, J.-C.1
Gray, M.D.2
Oshima, J.3
Loeb, L.A.4
-
144
-
-
0032545515
-
Werner syndrome protein. I. DNA helicase and DNA exonuclease reside on the same polypeptide
-
Shen J-C, Gray MD, Oshima J, Kamath-Loeb AS, Fry M and Loeb LA (1998b) Werner syndrome protein. I. DNA helicase and DNA exonuclease reside on the same polypeptide. J Biol Chem 273: 34139-34144
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 34139-34144
-
-
Shen, J.-C.1
Gray, M.D.2
Oshima, J.3
Kamath-Loeb, A.S.4
Fry, M.5
Loeb, L.A.6
-
145
-
-
0034192020
-
The Werner syndrome gene - The molecular basis of RecQ helicase-deficiency diseases
-
Shen J-C and Loeb LA (2000a) The Werner syndrome gene - the molecular basis of RecQ helicase-deficiency diseases. Trends Genet 16: 213-220
-
(2000)
Trends Genet.
, vol.16
, pp. 213-220
-
-
Shen, J.-C.1
Loeb, L.A.2
-
146
-
-
0034283889
-
Werner syndrome exonuclease catalyzes structure-dependent degradation of DNA
-
Shen J-C and Loeb LA (2000b) Werner syndrome exonuclease catalyzes structure-dependent degradation of DNA. Nucleic Acids Res 28: 3260-3268
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 3260-3268
-
-
Shen, J.-C.1
Loeb, L.A.2
-
147
-
-
0033545238
-
Detection by epitope-defined monoclonal antibodies of Werner DNA helicases in the nucleoplasm and their upregulation by cell transformation and immortalization
-
Shiratori M, Sakamoto S, Suzuki N, Tokutake Y, Kawabe Y, Enomoto T, Sugimoto M, Goto M, Matsumoto T and Furuichi Y (1999) Detection by epitope-defined monoclonal antibodies of Werner DNA helicases in the nucleoplasm and their upregulation by cell transformation and immortalization. J Cell Biol 144: 1-9
-
(1999)
J. Cell Biol.
, vol.144
, pp. 1-9
-
-
Shiratori, M.1
Sakamoto, S.2
Suzuki, N.3
Tokutake, Y.4
Kawabe, Y.5
Enomoto, T.6
Sugimoto, M.7
Goto, M.8
Matsumoto, T.9
Furuichi, Y.10
-
148
-
-
0035018021
-
G-quadruplex DNA structures - Variations on a theme
-
Simonsson T (2001) G-quadruplex DNA structures - variations on a theme. Biol Chem 382: 621-628
-
(2001)
Biol. Chem.
, vol.382
, pp. 621-628
-
-
Simonsson, T.1
-
149
-
-
0033951868
-
Characterization of genetic interactions with RFA1: The role of RPA in DNA replication and telomere maintenance
-
Smith J, Zou H and Rothstein R (2000) Characterization of genetic interactions with RFA1: the role of RPA in DNA replication and telomere maintenance. Biochimie 82: 71-78
-
(2000)
Biochimie
, vol.82
, pp. 71-78
-
-
Smith, J.1
Zou, H.2
Rothstein, R.3
-
150
-
-
0018890645
-
Intraclonal variation in proliferative potential of human diploid fibroblasts: Stochastic mechanism for cellular aging
-
Smith JR and Whitney RG (1980) Intraclonal variation in proliferative potential of human diploid fibroblasts: stochastic mechanism for cellular aging. Science 207: 82-84
-
(1980)
Science
, vol.207
, pp. 82-84
-
-
Smith, J.R.1
Whitney, R.G.2
-
151
-
-
0033560796
-
The DNA-dependent protein kinase
-
Smith GCM and Jackson SP (1999) The DNA-dependent protein kinase. Genes Dev 13: 916-934
-
(1999)
Genes Dev.
, vol.13
, pp. 916-934
-
-
Smith, G.C.M.1
Jackson, S.P.2
-
152
-
-
0034623378
-
Interaction of human Ku70 with TRF2
-
Song K, Jung D, Jung Y, Lee S-G and Lee I (2000) Interaction of human Ku70 with TRF2. FEBS Lett 481: 81-85
-
(2000)
FEBS Lett.
, vol.481
, pp. 81-85
-
-
Song, K.1
Jung, D.2
Jung, Y.3
Lee, S.-G.4
Lee, I.5
-
153
-
-
0033151615
-
p53-mediated apoptosis is attenuated in Werner syndrome cells
-
Spillare EA, Robles AI, Wang XW, Shen J-C, Yu C-E, Schellenberg GD and Harris CC (1999) p53-mediated apoptosis is attenuated in Werner syndrome cells. Genes Dev 13: 1355-1360
-
(1999)
Genes Dev.
, vol.13
, pp. 1355-1360
-
-
Spillare, E.A.1
Robles, A.I.2
Wang, X.W.3
Shen, J.-C.4
Yu, C.-E.5
Schellenberg, G.D.6
Harris, C.C.7
-
154
-
-
0037023763
-
p53 binds telomeric single strand overhangs and t-loop junctions in vitro
-
Stansel RM, Subramanian D and Griffith JD (2002) p53 binds telomeric single strand overhangs and t-loop junctions in vitro. J Biol Chem 277: 11625-11628
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 11625-11628
-
-
Stansel, R.M.1
Subramanian, D.2
Griffith, J.D.3
-
155
-
-
0033135161
-
The Saccharomyces cerevisiae Sgs1 helicase efficiently unwinds G-G paired DNAs
-
Sun H, Bennett RJ and Maizels N (1999) The Saccharomyces cerevisiae Sgs1 helicase efficiently unwinds G-G paired DNAs. Nucleic Acids Res 27: 1978-1984
-
(1999)
Nucleic Acids Res.
, vol.27
, pp. 1978-1984
-
-
Sun, H.1
Bennett, R.J.2
Maizels, N.3
-
156
-
-
0024843757
-
Telomeric DNA dimerizes by formation of guanine tetrads between hairpin loops
-
Sundquist WI and Klug A (1989) Telomeric DNA dimerizes by formation of guanine tetrads between hairpin loops. Nature 342: 825-829
-
(1989)
Nature
, vol.342
, pp. 825-829
-
-
Sundquist, W.I.1
Klug, A.2
-
157
-
-
0030757524
-
DNA helicase activity in Werner's syndrome gene product synthesized in a baculovirus system
-
Suzuki N, Shimamoto A, Imamura O, Kuromitsu J, Kitao S, Goto M and Furuichi Y (1997) DNA helicase activity in Werner's syndrome gene product synthesized in a baculovirus system. Nucleic Acids Res 425: 2973-2978
-
(1997)
Nucleic Acids Res.
, vol.425
, pp. 2973-2978
-
-
Suzuki, N.1
Shimamoto, A.2
Imamura, O.3
Kuromitsu, J.4
Kitao, S.5
Goto, M.6
Furuichi, Y.7
-
158
-
-
0033151822
-
Werner syndrome helicase contains a 5′-3′ exonuclease activity that digests DNA and RNA strands in DNA/DNA and RNA/DNA duplexes dependent on unwinding
-
Suzuki N, Shiratori M, Goto M and Furuichi Y (1999) Werner syndrome helicase contains a 5′-3′ exonuclease activity that digests DNA and RNA strands in DNA/DNA and RNA/DNA duplexes dependent on unwinding. Nucleic Acids Res 27: 2361-2368
-
(1999)
Nucleic Acids Res.
, vol.27
, pp. 2361-2368
-
-
Suzuki, N.1
Shiratori, M.2
Goto, M.3
Furuichi, Y.4
-
159
-
-
0034633732
-
Werner protein recruits DNA polymerase δ to the nucleolus
-
Szekely AM, Chen Y-H, Zhang C, Oshima J and Weissman SM (2000) Werner protein recruits DNA polymerase δ to the nucleolus. Proc Natl Acad Sci USA 97: 11365-11370
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 11365-11370
-
-
Szekely, A.M.1
Chen, Y.-H.2
Zhang, C.3
Oshima, J.4
Weissman, S.M.5
-
160
-
-
0019979019
-
Altered frequency of initiation sites of DNA replication in Werner's syndrome cells
-
Takeuchi F, Hanaoka F, Goto M, Akaoka I, Hori T-a, Yamada M-a and Miyamoto T (1982a) Altered frequency of initiation sites of DNA replication in Werner's syndrome cells. Hum Genet 60: 365-368
-
(1982)
Hum. Genet.
, vol.60
, pp. 365-368
-
-
Takeuchi, F.1
Hanaoka, F.2
Goto, M.3
Akaoka, I.4
Hori, T.-A.5
Yamada, M.-A.6
Miyamoto, T.7
-
161
-
-
0020306698
-
Prolongation of δ phase and whole cell cycle in Werner's syndrome fibroblasts
-
Takeuchi F, Hanaoka F, Goto M, Yamada M and Miyamoto T (1982b) Prolongation of δ phase and whole cell cycle in Werner's syndrome fibroblasts. Exp Gerontol 17: 473-480
-
(1982)
Exp. Gerontol.
, vol.17
, pp. 473-480
-
-
Takeuchi, F.1
Hanaoka, F.2
Goto, M.3
Yamada, M.4
Miyamoto, T.5
-
162
-
-
0033508431
-
Characterization of a fission yeast SUMO-1 homologue, Pmt3p, required for multiple nuclear events, including the control of telomere length and chromosome segregation
-
Tanaka K, Nishide J, Okazaki K, Kato H, Niwa O, Nakagawa T, Matsuda H, Kawamukai M and Murakami Y (1999) Characterization of a fission yeast SUMO-1 homologue, Pmt3p, required for multiple nuclear events, including the control of telomere length and chromosome segregation. Mol Cell Biol 19: 8660-8672
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 8660-8672
-
-
Tanaka, K.1
Nishide, J.2
Okazaki, K.3
Kato, H.4
Niwa, O.5
Nakagawa, T.6
Matsuda, H.7
Kawamukai, M.8
Murakami, Y.9
-
163
-
-
0031825116
-
The thermodynamics and evolution of complexity in biological systems
-
Toussaint O and Schneider ED (1998) The thermodynamics and evolution of complexity in biological systems. Comp Biochem Physiol A 120: 3-9
-
(1998)
Comp. Biochem. Physiol. A
, vol.120
, pp. 3-9
-
-
Toussaint, O.1
Schneider, E.D.2
-
164
-
-
0036311563
-
Involvement of replicative polymerases, Te11p, Mec1p, Cdc13p, and the Ku complex in telomere-telomere recombination
-
Tsai Y-L, Tseng S-F, Chang S-H, Lin C-C and Teng S-C (2002) Involvement of replicative polymerases, Te11p, Mec1p, Cdc13p, and the Ku complex in telomere-telomere recombination. Mol Cell Biol 22: 5679-5687
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 5679-5687
-
-
Tsai, Y.-L.1
Tseng, S.-F.2
Chang, S.-H.3
Lin, C.-C.4
Teng, S.-C.5
-
165
-
-
0025189911
-
Functions of replication factor C and proliferating-cell nuclear antigen: Functional similarity of DNA polymerase accessory proteins from human cells and bacteriophage T4
-
Tsurimoto T and Stillman B (1990) Functions of replication factor C and proliferating-cell nuclear antigen: functional similarity of DNA polymerase accessory proteins from human cells and bacteriophage T4. Proc Natl Acad Sci USA 87: 1023-1027
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 1023-1027
-
-
Tsurimoto, T.1
Stillman, B.2
-
167
-
-
0842338715
-
2+ and other transition metals at low concentration induce the right-to-left helical transformation of poly[d(G-C)]
-
2+ and other transition metals at low concentration induce the right-to-left helical transformation of poly[d(G-C)]. EMBO J 1: 777-782
-
(1982)
EMBO J.
, vol.1
, pp. 777-782
-
-
van de Sande, J.H.1
McIntosh, L.P.2
Jovin, T.M.3
-
168
-
-
0031027618
-
Control of telomere length by the human telomeric protein TRF1
-
van Steensel B and de Lange T (1997) Control of telomere length by the human telomeric protein TRF1. Nature 385: 740-743
-
(1997)
Nature
, vol.385
, pp. 740-743
-
-
van Steensel, B.1
de Lange, T.2
-
169
-
-
0032489012
-
TRF2 protects human telomeres from end-to-end fusions
-
van Steensel B, Smogorzewska A and de Lange T (1998) TRF2 protects human telomeres from end-to-end fusions. Cell 92: 401-413
-
(1998)
Cell
, vol.92
, pp. 401-413
-
-
van Steensel, B.1
Smogorzewska, A.2
de Lange, T.3
-
170
-
-
0036510162
-
Molecular characterization of inter-telomere and intra-telomere mutations in human ALT cells
-
Varley H, Pickett HA, Foxon JL, Reddel RR and Royle NJ (2002) Molecular characterization of inter-telomere and intra-telomere mutations in human ALT cells. Nat Genet 30: 301-305
-
(2002)
Nat. Genet.
, vol.30
, pp. 301-305
-
-
Varley, H.1
Pickett, H.A.2
Foxon, J.L.3
Reddel, R.R.4
Royle, N.J.5
-
172
-
-
0034176307
-
The recombination-replication interface
-
von Hippel PH (2000) The recombination-replication interface. Trends Biochem Sci 25: 155
-
(2000)
Trends Biochem. Sci.
, vol.25
, pp. 155
-
-
von Hippel, P.H.1
-
173
-
-
0037077223
-
Colocalization, physical, and functional interaction between Werner and Bloom syndrome proteins
-
von Kobbe C, Karmakar P, Dawut L, Opresko P, Zeng X, Brosh RM jr, Hickson ID and Bohr VA (2002) Colocalization, physical, and functional interaction between Werner and Bloom syndrome proteins. J Biol Chem 277: 22035-22044
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 22035-22044
-
-
von Kobbe, C.1
Karmakar, P.2
Dawut, L.3
Opresko, P.4
Zeng, X.5
Brosh Jr., R.M.6
Hickson, I.D.7
Bohr, V.A.8
-
174
-
-
0033942779
-
Role of oxidative stress in telomere length regulation and replicative senescence
-
von Zglinicki T (2000) Role of oxidative stress in telomere length regulation and replicative senescence. Ann N Y Acad Sci 908: 99-110
-
(2000)
Ann. N. Y. Acad. Sci.
, vol.908
, pp. 99-110
-
-
von Zglinicki, T.1
-
175
-
-
0020676319
-
Is there left-handed DNA at the ends of yeast chromosomes?
-
Walmsley RM, Szostak JW and Petes TD (1983) Is there left-handed DNA at the ends of yeast chromosomes? Nature 302: 84-86
-
(1983)
Nature
, vol.302
, pp. 84-86
-
-
Walmsley, R.M.1
Szostak, J.W.2
Petes, T.D.3
-
176
-
-
0029002965
-
Sgs1: A eukaryotic homolog of E. coli RecQ that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation
-
Watt PM, Louis EJ, Borts RH and Hickson ID (1995) Sgs1: a eukaryotic homolog of E. coli RecQ that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation. Cell 81: 253-260
-
(1995)
Cell
, vol.81
, pp. 253-260
-
-
Watt, P.M.1
Louis, E.J.2
Borts, R.H.3
Hickson, I.D.4
-
177
-
-
0034813364
-
ARF in replicative and induced senescence of human fibroblasts
-
ARF in replicative and induced senescence of human fibroblasts. Mol Cell Biol 21: 6748-6757
-
(2001)
Mol. Cell Biol.
, vol.21
, pp. 6748-6757
-
-
Wei, W.1
Hemmer, R.M.2
Sedivy, J.M.3
-
178
-
-
0342614989
-
Intranuclear anchoring of repetitive DNA sequences: Centromeres, telomeres, and ribosomal DNA
-
Weipoltshammer K, Schofer C, Almeder M, Philimonenko VV, Frei K, Wachtler F and Hozak P (1999) Intranuclear anchoring of repetitive DNA sequences: centromeres, telomeres, and ribosomal DNA. J Cell Biol 147: 1409-1418
-
(1999)
J. Cell Biol.
, vol.147
, pp. 1409-1418
-
-
Weipoltshammer, K.1
Schofer, C.2
Almeder, M.3
Philimonenko, V.V.4
Frei, K.5
Wachtler, F.6
Hozak, P.7
-
179
-
-
0030978765
-
The DNA structures at the ends of eukaryotic chromosomes
-
Wellinger RJ and Sen D (1997) The DNA structures at the ends of eukaryotic chromosomes. Eur J Cancer 33: 735-749
-
(1997)
Eur. J. Cancer
, vol.33
, pp. 735-749
-
-
Wellinger, R.J.1
Sen, D.2
-
181
-
-
0003074784
-
Early chromosomal changes in SV40-infected human fibroblast cultures
-
Wolman SR, Hirschhorn K and Todaro GJ (1964) Early chromosomal changes in SV40-infected human fibroblast cultures. Cytogenetics 3: 45-61
-
(1964)
Cytogenetics
, vol.3
, pp. 45-61
-
-
Wolman, S.R.1
Hirschhorn, K.2
Todaro, G.J.3
-
182
-
-
0034730633
-
NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells
-
Wu G, Lee W-H and Chen P-L (2000) NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells. J Biol Chem 275: 30618-30622
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 30618-30622
-
-
Wu, G.1
Lee, W.-H.2
Chen, P.-L.3
-
183
-
-
0033987424
-
Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts
-
Wyllie FS, Jones CJ, Skinner JW, Haughton ME, Wallis C, Wynford-Thomas D, Faragher RGA and Kipling D (2000) Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts. Nat Genet 24: 16-17
-
(2000)
Nat. Genet.
, vol.24
, pp. 16-17
-
-
Wyllie, F.S.1
Jones, C.J.2
Skinner, J.W.3
Haughton, M.E.4
Wallis, C.5
Wynford-Thomas, D.6
Faragher, R.G.A.7
Kipling, D.8
-
184
-
-
0037022821
-
A minimal exonuclease domain of WRN forms a hexamer on DNA and possesses both 3′-5′ exonuclease and 5′-protruding strand endonuclease activities
-
Xue Y, Ratcliff GC, Wang H, Davis-Searles PR, Gray MD, Erie DA and Redinbo MR (2002) A minimal exonuclease domain of WRN forms a hexamer on DNA and possesses both 3′-5′ exonuclease and 5′-protruding strand endonuclease activities. Biochemistry 41: 2901-2912
-
(2002)
Biochemistry
, vol.41
, pp. 2901-2912
-
-
Xue, Y.1
Ratcliff, G.C.2
Wang, H.3
Davis-Searles, P.R.4
Gray, M.D.5
Erie, D.A.6
Redinbo, M.R.7
-
185
-
-
0031792774
-
Sp1-mediated transcription of the Werner helicase gene is modulated by Rb and p53
-
Yamabe Y, Shimamoto A, Goto M, Yokota J, Sugawara M and Furuichi Y (1998) Sp1-mediated transcription of the Werner helicase gene is modulated by Rb and p53. Mol Cell Biol 18: 6191-6200
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 6191-6200
-
-
Yamabe, Y.1
Shimamoto, A.2
Goto, M.3
Yokota, J.4
Sugawara, M.5
Furuichi, Y.6
-
186
-
-
0028883491
-
FFA-1, a protein that promotes the formation of replication centers within nuclei
-
Yan H and Newport J (1995) FFA-1, a protein that promotes the formation of replication centers within nuclei. Science 269: 1883-1885
-
(1995)
Science
, vol.269
, pp. 1883-1885
-
-
Yan, H.1
Newport, J.2
-
187
-
-
0031848284
-
Replication focus-forming activity 1 and the Werner syndrome gene product
-
Yan H, Chen C-Y, Kobayashi R and Newport J (1998) Replication focus-forming activity 1 and the Werner syndrome gene product. Nat Genet 19: 375-378
-
(1998)
Nat. Genet.
, vol.19
, pp. 375-378
-
-
Yan, H.1
Chen, C.-Y.2
Kobayashi, R.3
Newport, J.4
-
188
-
-
18544377842
-
The processing of Holliday junctions by BLM and WRN helicases is regulated by p53
-
Yang Q, Zhang R, Wang XW, Spillare EA, Linke SP, Subramanian D, Griffith JD, Li JL, Hickson ID, Shen JC, Loeb LA, Mazur SJ, Appella E, Brosh RM jr, Karmakar P, Bohr VA and Harris CC (2002) The processing of Holliday junctions by BLM and WRN helicases is regulated by p53. J Biol Chem 277: 31980-31987
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 31980-31987
-
-
Yang, Q.1
Zhang, R.2
Wang, X.W.3
Spillare, E.A.4
Linke, S.P.5
Subramanian, D.6
Griffith, J.D.7
Li, J.L.8
Hickson, I.D.9
Shen, J.C.10
Loeb, L.A.11
Mazur, S.J.12
Appella, E.13
Brosh Jr., R.M.14
Karmakar, P.15
Bohr, V.A.16
Harris, C.C.17
-
189
-
-
0035851181
-
Werner syndrome protein is regulated and phosphorylated by DNA-dependent protein kinase
-
Yannone SM, Roy S, Chan DW, Murphy MB, Huang S, Campisi J and Chen DJ (2001) Werner syndrome protein is regulated and phosphorylated by DNA-dependent protein kinase. J Biol Chem 276: 38242-38248
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 38242-38248
-
-
Yannone, S.M.1
Roy, S.2
Chan, D.W.3
Murphy, M.B.4
Huang, S.5
Campisi, J.6
Chen, D.J.7
-
190
-
-
0033199695
-
Telomerase-negative immortalized human cells contain a novel type of promyelocytic leukemia (PML) body
-
Yeager TR, Neumann AA, Englezou A, Huschtscha LI, Noble JR and Reddel RR (1999) Telomerase-negative immortalized human cells contain a novel type of promyelocytic leukemia (PML) body. Cancer Res 59: 4175-4179
-
(1999)
Cancer Res.
, vol.59
, pp. 4175-4179
-
-
Yeager, T.R.1
Neumann, A.A.2
Englezou, A.3
Huschtscha, L.I.4
Noble, J.R.5
Reddel, R.R.6
-
191
-
-
0034595239
-
Ubiquitin-like proteins: New wines in new bottles
-
Yeh ETH, Gong L and Kamitani T (2000) Ubiquitin-like proteins: new wines in new bottles. Gene 248: 1-14
-
(2000)
Gene
, vol.248
, pp. 1-14
-
-
Yeh, E.T.H.1
Gong, L.2
Kamitani, T.3
-
192
-
-
0032491903
-
DNA topoisomerase II cleavage of telomeres in vitro and in vivo
-
1395
-
Yoon HJ, Choi IY, Kang MR, Kim SS, Muller MT, Spitzner JR and Chung IK (1998) DNA topoisomerase II cleavage of telomeres in vitro and in vivo. Biochem Biophys Acta 1395: 110-120
-
(1998)
Biochem. Biophys. Acta
, pp. 110-120
-
-
Yoon, H.J.1
Choi, I.Y.2
Kang, M.R.3
Kim, S.S.4
Muller, M.T.5
Spitzner, J.R.6
Chung, I.K.7
-
193
-
-
15844409553
-
Positional cloning of the Werner's syndrome gene
-
Yu C-E, Oshima J, Fu Y-H, Wijsman EM, Hisama F, Alisch R, Matthews S, Nakura J, Miki T, Ouais S, Martin GM, Mulligan J and Schellenberg GD (1996) Positional cloning of the Werner's syndrome gene. Science 272: 258-262
-
(1996)
Science
, vol.272
, pp. 258-262
-
-
Yu, C.-E.1
Oshima, J.2
Fu, Y.-H.3
Wijsman, E.M.4
Hisama, F.5
Alisch, R.6
Matthews, S.7
Nakura, J.8
Miki, T.9
Ouais, S.10
Martin, G.M.11
Mulligan, J.12
Schellenberg, G.D.13
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