Detection by epitope-defined monoclonal antibodies of Werner DNA helicases in the nucleoplasm and their upregulation by cell transformation and immortalization

Journal of Cell Biology

Volumn 144, Issue 1, 1999, Pages 1-9

  Shiratori, Miwa ^a   Sakamoto, Sakae ^a   Suzuki, Noriyuki ^a   Tokutake, Yoshiki ^a   Kawabe, Yoichi ^b   Enomoto, Takemi ^b   Sugimoto, Masanobu ^a   Goto, Makoto ^c   Matsumoto, Takehisa ^a   Furuichi, Yasuhiro ^a  

^a AGENE Research Institute   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

^c Tokyo Metropolitan Ohtsuka Hospital   (Japan)

Author keywords

Aging; Genetic instability; Nucleoplasmic localization; RecQ DNA helicase; Werner's syndrome

Indexed keywords

HELICASE; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG; WRN HELICASE;

ANIMAL CELL; ANTIBODY SPECIFICITY; ARTICLE; CELL PROLIFERATION; CELL TRANSFORMATION; CHROMATIN CONDENSATION; ENZYME BINDING; ENZYME STRUCTURE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE DIAGNOSIS; RAT; WERNER SYNDROME;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL LINE, TRANSFORMED; CELL TRANSFORMATION, VIRAL; CELLS, CULTURED; DNA HELICASES; EPITOPE MAPPING; EPITOPES, B-LYMPHOCYTE; FIBROBLASTS; HELA CELLS; HUMANS; MICE; MICE, INBRED BALB C; RATS; RATS, WISTAR; TUMOR CELLS, CULTURED; UP-REGULATION;

ANIMALIA; HUMAN HERPESVIRUS 4;

EID: 0033545238     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.144.1.1     Document Type: Article

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