-
1
-
-
0024648089
-
Discovery of the non-A, non-B hepatitis virus: The end of the beginning or the beginning of the end
-
ALTER HJ: Discovery of the non-A, non-B hepatitis virus: the end of the beginning or the beginning of the end. Transfus. Med. Rev. (1989) 3(2):77-81.
-
(1989)
Transfus. Med. Rev.
, vol.3
, Issue.2
, pp. 77-81
-
-
Alter, H.J.1
-
2
-
-
0024511734
-
An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis
-
(4902)
-
KUO G, CHOO QL, ALTER HJ et al.: An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis. Science (1989) 244(4902):362-364.
-
(1989)
Science
, vol.244
, pp. 362-364
-
-
Kuo, G.1
Choo, Q.L.2
Alter, H.J.3
-
3
-
-
0037221473
-
Management of hepatitis C
-
ALBERTI A, BENVEGNU L: Management of hepatitis C. J. Hepatol. (2003) 38(Suppl.1):S104-S118.
-
(2003)
J. Hepatol.
, vol.38
, Issue.SUPPL. 1
-
-
Alberti, A.1
Benvegnu, L.2
-
4
-
-
0033230584
-
Hepatitis C virus: An overview of current approaches and progress
-
WALKER MA: Hepatitis C virus: an overview of current approaches and progress. Drug Discov. Today (1999) 4(11):518-529.
-
(1999)
Drug Discov. Today
, vol.4
, Issue.11
, pp. 518-529
-
-
Walker, M.A.1
-
6
-
-
0030807167
-
Hepatitis C virus infection in the development of hepatocellular carcinoma in cirrhosis
-
NAOUMOV NV, CHOKSHI S, METIVIER E, MAERTENS G, JOHNSON PJ, WILLIAMS R: Hepatitis C virus infection in the development of hepatocellular carcinoma in cirrhosis. J. Hepatol. (1997) 27(2):331-336.
-
(1997)
J. Hepatol.
, vol.27
, Issue.2
, pp. 331-336
-
-
Naoumov, N.V.1
Chokshi, S.2
Metivier, E.3
Maertens, G.4
Johnson, P.J.5
Williams, R.6
-
7
-
-
0025166005
-
Hepatitis C virus infection is associated with the development of hepatocellular carcinoma
-
SAITO I, MIYAMURA T, OHBAYASHI A et al.: Hepatitis C virus infection is associated with the development of hepatocellular carcinoma. Proc. Natl. Acad. Sci. USA (1990) 87(17):6547-6549.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, Issue.17
, pp. 6547-6549
-
-
Saito, I.1
Miyamura, T.2
Ohbayashi, A.3
-
8
-
-
0029791851
-
Hepatitis C virus infection as a major risk factor for hepatocellular carcinoma
-
CASELMANN WH, ALT M: Hepatitis C virus infection as a major risk factor for hepatocellular carcinoma. J. Hepatol. (1996) 24(2):61-66.
-
(1996)
J. Hepatol.
, vol.24
, Issue.2
, pp. 61-66
-
-
Caselmann, W.H.1
Alt, M.2
-
9
-
-
0030823524
-
Effect of hepatitis C and B virus infection on risk of hepatocellular carcinoma: A prospective study
-
TSAI JF, JENG JE, HO MS et al.: Effect of hepatitis C and B virus infection on risk of hepatocellular carcinoma: a prospective study. Br. J. Cancer (1997) 76(7):968-974.
-
(1997)
Br. J. Cancer
, vol.76
, Issue.7
, pp. 968-974
-
-
Tsai, J.F.1
Jeng, J.E.2
Ho, M.S.3
-
10
-
-
0031960043
-
Determinants of outcome of compensated hepatitis C virus-related cirrhosis
-
SERFATY L, AUMAITRE H, CHAZOUILLERES O et al.: Determinants of outcome of compensated hepatitis C virus-related cirrhosis. Hepatology (1998) 27(5):1435-1440.
-
(1998)
Hepatology
, vol.27
, Issue.5
, pp. 1435-1440
-
-
Serfaty, L.1
Aumaitre, H.2
Chazouilleres, O.3
-
11
-
-
0031894550
-
Hepatitis C
-
ALTER MJ, MAST EE, MOYER LA, MARGOLIS HS: Hepatitis C. Infect. Dis. Clin. North Am. (1998) 12(1):13-26.
-
(1998)
Infect. Dis. Clin. North Am.
, vol.12
, Issue.1
, pp. 13-26
-
-
Alter, M.J.1
Mast, E.E.2
Moyer, L.A.3
Margolis, H.S.4
-
12
-
-
0028050283
-
Epidemiological studies on hepatitis C virus infection: Detection, prevalence, exposure and prevention
-
NISHIOKA K: Epidemiological studies on hepatitis C virus infection: detection, prevalence, exposure and prevention. Intervirology (1994) 37(2):58-67.
-
(1994)
Intervirology
, vol.37
, Issue.2
, pp. 58-67
-
-
Nishioka, K.1
-
13
-
-
0029793741
-
Risk factors for the transmission of hepatitis C
-
ZEUZEM S, TEUBER G, LEE JH, RUSTER B, ROTH WK: Risk factors for the transmission of hepatitis C. J. Hepatol. (1996) 24(2):3-10.
-
(1996)
J. Hepatol.
, vol.24
, Issue.2
, pp. 3-10
-
-
Zeuzem, S.1
Teuber, G.2
Lee, J.H.3
Ruster, B.4
Roth, W.K.5
-
14
-
-
0036828783
-
Course and outcome of hepatitis C
-
HOOFNAGLE JH: Course and outcome of hepatitis C. Hepatology (2002) 36(5Suppl.1):S21-S29.
-
(2002)
Hepatology
, vol.36
, Issue.5 SUPPL. 1
-
-
Hoofnagle, J.H.1
-
15
-
-
0034993077
-
Hepatitis C virus genotypes: Distribution and clinical significance in patients with cirrhosis type C seen at tertiary referral centres in Europe
-
FATTOVICH G, RIBERO ML, PANTALENA M et al.: Hepatitis C virus genotypes: distribution and clinical significance in patients with cirrhosis type C seen at tertiary referral centres in Europe. J. Viral Hepat. (2001) 8(3):206-216.
-
(2001)
J. Viral Hepat.
, vol.8
, Issue.3
, pp. 206-216
-
-
Fattovich, G.1
Ribero, M.L.2
Pantalena, M.3
-
16
-
-
0030470530
-
Hepatitis C virus: Molecular biology and generic variability
-
BRECHOT C: Hepatitis C virus: molecular biology and generic variability. Dig. Dis. Sci. (1996) 41(12Suppl.):6S-S21.
-
(1996)
Dig. Dis. Sci.
, vol.41
, Issue.12 SUPPL.
-
-
Brechot, C.1
-
17
-
-
0034997875
-
Outcome of liver disease in a large cohort of histologically proven chronic hepatitis C: Influence of HCV genotype
-
ROFFI L, REDAELLI A, COLLOREDO G et al.: Outcome of liver disease in a large cohort of histologically proven chronic hepatitis C: influence of HCV genotype. Eur. J. Gastroenterol. Hepatol. (2001) 13(5):501-506.
-
(2001)
Eur. J. Gastroenterol. Hepatol.
, vol.13
, Issue.5
, pp. 501-506
-
-
Roffi, L.1
Redaelli, A.2
Colloredo, G.3
-
18
-
-
0034120427
-
Clinical significance of hepatitis C virus genotypes
-
ZEIN NN: Clinical significance of hepatitis C virus genotypes. Clin. Microbiol. Rev. (2000) 13(2):223-235.
-
(2000)
Clin. Microbiol. Rev.
, vol.13
, Issue.2
, pp. 223-235
-
-
Zein, N.N.1
-
19
-
-
0033932002
-
Clinical significance of hepatitis C virus genotypes and quasispecies
-
FARCI P, PURCELL RH: Clinical significance of hepatitis C virus genotypes and quasispecies. Semin. Liver Dis. (2000) 20(1):103-126.
-
(2000)
Semin. Liver Dis.
, vol.20
, Issue.1
, pp. 103-126
-
-
Farci, P.1
Purcell, R.H.2
-
21
-
-
0027214322
-
At least 12 genotypes of hepatitis C virus predicted by sequence analysis of the putative E1 gene of isolates collected worldwide
-
BUKH J, PURCELL RH, MILLER RH: At least 12 genotypes of hepatitis C virus predicted by sequence analysis of the putative E1 gene of isolates collected worldwide. Prac. Natl. Acad. Sci. USA (1993) 90(17):8234-8238.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, Issue.17
, pp. 8234-8238
-
-
Bukh, J.1
Purcell, R.H.2
Miller, R.H.3
-
22
-
-
0025991559
-
Gene mapping of the putative structural region of the hepatitis C virus genome by in vitro processing analysis
-
HIJIKATA M, KATO N, OOTSUYAMAY, ENAKAGAWA M, SHIMOTOHNO K: Gene mapping of the putative structural region of the hepatitis C virus genome by in vitro processing analysis. Proc. Natl. Acad. Sci. USA (1991) 88(13):5547-5551.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, Issue.13
, pp. 5547-5551
-
-
Hijikata, M.1
Kato, N.2
Ootsuyama, Y.3
Enakagawa, M.4
Shimotohno, K.5
-
23
-
-
0025968921
-
Genetic organization and diversity of the hepatitis C virus
-
CHOO QL, RICHMAN KH, HAN JH et al.: Genetic organization and diversity of the hepatitis C virus. Proc. Natl. Acad. Sci. USA (1991) 88(6):2451-2455.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, Issue.6
, pp. 2451-2455
-
-
Choo, Q.L.1
Richman, K.H.2
Han, J.H.3
-
24
-
-
0025862146
-
Molecular biology of the hepatitis C viruses: Implications for diagnosis, development and control of viral disease
-
HOUGHTON M, WEINER A, HAN J, KUO G, CHOO QL: Molecular biology of the hepatitis C viruses: implications for diagnosis, development and control of viral disease. Hepatology (1991) 14(2):381-388.
-
(1991)
Hepatology
, vol.14
, Issue.2
, pp. 381-388
-
-
Houghton, M.1
Weiner, A.2
Han, J.3
Kuo, G.4
Choo, Q.L.5
-
25
-
-
0033429914
-
Molecular virology of the hepatitis C virus
-
DE FRANCESCO R: Molecular virology of the hepatitis C virus. J. Hepatol. (1999) 31(Suppl.1):47-53.
-
(1999)
J. Hepatol.
, vol.31
, Issue.SUPPL. 1
, pp. 47-53
-
-
De Francesco, R.1
-
26
-
-
0032876872
-
Processing and functions of hepatitis C virus proteins
-
SUZUKI R, SUZUKI T, ISHII K, MATSUURA Y, MIYAMURA T: Processing and functions of hepatitis C virus proteins. Intervirology (1999) 42(2-3):145-152.
-
(1999)
Intervirology
, vol.42
, Issue.2-3
, pp. 145-152
-
-
Suzuki, R.1
Suzuki, T.2
Ishii, K.3
Matsuura, Y.4
Miyamura, T.5
-
27
-
-
2642590958
-
Complex of NS3 protease and NS4A peptide of BK strain hepatitis C virus: A 2.2 Å resolution structure in a hexagonal crystal form
-
YAN Y, LI Y, MUNSHI S et al.: Complex of NS3 protease and NS4A peptide of BK strain hepatitis C virus: a 2.2 Å resolution structure in a hexagonal crystal form. Protein Sci. (1998) 7(4):837-847.
-
(1998)
Protein Sci.
, vol.7
, Issue.4
, pp. 837-847
-
-
Yan, Y.1
Li, Y.2
Munshi, S.3
-
28
-
-
0032518490
-
Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: The crystal structure provides insights into the mode of unwinding
-
KIM JL, MORGENSTERN KA, GRIFFITH JP et al.: Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: the crystal structure provides insights into the mode of unwinding. Structure (1998) 6(1):89-100.
-
(1998)
Structure
, vol.6
, Issue.1
, pp. 89-100
-
-
Kim, J.L.1
Morgenstern, K.A.2
Griffith, J.P.3
-
29
-
-
0034870450
-
Structure-based mutational analysis of the hepatitis C virus NS3 helicase
-
TAI CL, PAN WC, LIAW SH YANG UC, HWANG LH, CHEN DS: Structure-based mutational analysis of the hepatitis C virus NS3 helicase. J. Virol. (2001) 75(17):8289-8297.
-
(2001)
J. Virol.
, vol.75
, Issue.17
, pp. 8289-8297
-
-
Tai, C.L.1
Pan, W.C.2
Liaw, S.H.3
Yang, U.C.4
Hwang, L.H.5
Chen, D.S.6
-
30
-
-
0031888452
-
Crystallization and preliminary X-ray crystallographic analysis of the helicase domain of hepatitis C virus NS3 protein
-
KANG LW, CHO HS, CHA SS et al.: Crystallization and preliminary X-ray crystallographic analysis of the helicase domain of hepatitis C virus NS3 protein. Acta. Crystallogr. D Biol. Crystallogr. (1998) 54(Pt1):121-123.
-
(1998)
Acta. Crystallogr. D Biol. Crystallogr.
, vol.54
, Issue.PART 1
, pp. 121-123
-
-
Kang, L.W.1
Cho, H.S.2
Cha, S.S.3
-
31
-
-
0034629363
-
Inhibition of the hepatitis C virus NS3/4A protease. The crystal structures of two protease-inhibitor complexes
-
DI MARCO S, RIZZI M, VOLPARI C et al.: Inhibition of the hepatitis C virus NS3/4A protease. The crystal structures of two protease-inhibitor complexes. J. Biol. Chem. (2000) 275(10):7152-7157.
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.10
, pp. 7152-7157
-
-
Di Marco, S.1
Rizzi, M.2
Volpari, C.3
-
32
-
-
0032974384
-
The NS3/4A protease of the hepatitis C virus: Unravelling structure and function of an unusual enzyme and a prime target for antiviral therapy
-
BARTENSCHLAGER R. The NS3/4A protease of the hepatitis C virus: unravelling structure and function of an unusual enzyme and a prime target for antiviral therapy. J. Viral Hepat. (1999) 6(3):165-181.
-
(1999)
J. Viral Hepat.
, vol.6
, Issue.3
, pp. 165-181
-
-
Bartenschlager, R.1
-
33
-
-
16044364658
-
Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide
-
KIM JL, MORGENSTERN KA, LIN C et al.: Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide. Cell (1996) 87(2):343-355.
-
(1996)
Cell
, vol.87
, Issue.2
, pp. 343-355
-
-
Kim, J.L.1
Morgenstern, K.A.2
Lin, C.3
-
34
-
-
0033539482
-
Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus
-
BRESSANELLI S, TOMEI L, ROUSSEL A et al.: Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus. Proc. Natl. Acad. Sci. USA (1999) 96(23):13034-13039.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, Issue.23
, pp. 13034-13039
-
-
Bressanelli, S.1
Tomei, L.2
Roussel, A.3
-
35
-
-
0032876683
-
Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site
-
LESBURG CA, CABLE MB, FERRARI E, HONG Z, MANNARINO AF, WEBER PC: Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site. Nature Struct. Biol. (1999) 6(10):937-943.
-
(1999)
Nature Struct. Biol.
, vol.6
, Issue.10
, pp. 937-943
-
-
Lesburg, C.A.1
Cable, M.B.2
Ferrari, E.3
Hong, Z.4
Mannarino, A.F.5
Weber, P.C.6
-
36
-
-
0035120615
-
Mutational analysis of the structure and functions of hepatitis C virus RNA-dependent RNA polymerase
-
QIN W, YAMASHITA T, SHIROTA Y, LIN Y, WEI W, MURAKAMI S: Mutational analysis of the structure and functions of hepatitis C virus RNA-dependent RNA polymerase. Hepatology (2001) 33(3):728-737.
-
(2001)
Hepatology
, vol.33
, Issue.3
, pp. 728-737
-
-
Qin, W.1
Yamashita, T.2
Shirota, Y.3
Lin, Y.4
Wei, W.5
Murakami, S.6
-
37
-
-
0036752091
-
Nucleotide triphosphatase/helicase of hepatitis C virus as a target for antiviral therapy
-
BOROWSKI P, SCHALINSKI S, SCHMITZ H: Nucleotide triphosphatase/helicase of hepatitis C virus as a target for antiviral therapy. Antiviral Res. (2002) 55(3):397-412.
-
(2002)
Antiviral Res.
, vol.55
, Issue.3
, pp. 397-412
-
-
Borowski, P.1
Schalinski, S.2
Schmitz, H.3
-
38
-
-
0036091674
-
Advances in hepatitis C: What is coming in the next 5 years?
-
LOCARNINI SA, BARTHOLOMEUSZ A: Advances in hepatitis C: what is coming in the next 5 years? J. Gastroenterol. Hepatol. (2002) 17(4):442-447.
-
(2002)
J. Gastroenterol. Hepatol.
, vol.17
, Issue.4
, pp. 442-447
-
-
Locarnini, S.A.1
Bartholomeusz, A.2
-
40
-
-
0027436831
-
A second hepatitis C virus-encoded protease
-
GRAKOUI A, MCCOURT DW, WYCHOWSKI C, FEINSTONE SM, RICE CM: A second hepatitis C virus-encoded protease. Proc. Natl. Acad. Sci. USA (1993) 90(22):10583-10587.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, Issue.22
, pp. 10583-10587
-
-
Grakoui, A.1
Mccourt, D.W.2
Wychowski, C.3
Feinstone, S.M.4
Rice, C.M.5
-
41
-
-
0033521138
-
Inhibition of hepatitis C virus NS2/3 processing by NS4A peptides. Implications for control of viral processing
-
DARKE PL, JACOBS AP, WAXMAN L, KUO LC: Inhibition of hepatitis C virus NS2/3 processing by NS4A peptides. Implications for control of viral processing. J. Biol. Chem. (1999) 274(49):34511-34514.
-
(1999)
J. Biol. Chem.
, vol.274
, Issue.49
, pp. 34511-34514
-
-
Darke, P.L.1
Jacobs, A.P.2
Waxman, L.3
Kuo, L.C.4
-
42
-
-
0036017204
-
The non-structural NS5A protein of hepatitis C virus: An expanding, multifunctional role in enhancing hepatitis C virus pathogenesis
-
REYES GR: The non-structural NS5A protein of hepatitis C virus: an expanding, multifunctional role in enhancing hepatitis C virus pathogenesis. J. Biomed. Sci. (2002) 9(3):187-197.
-
(2002)
J. Biomed. Sci.
, vol.9
, Issue.3
, pp. 187-197
-
-
Reyes, G.R.1
-
43
-
-
0344765507
-
Repression of the PKR protein kinase by the hepatitis C virus NS5A protein: A potential mechanism of interferon resistance
-
GALE MJ Jr, KORTH MJ, KATZE MG: Repression of the PKR protein kinase by the hepatitis C virus NS5A protein: a potential mechanism of interferon resistance. Clin. Diagn. Virol. (1998) 10(2-3):157-162.
-
(1998)
Clin. Diagn. Virol.
, vol.10
, Issue.2-3
, pp. 157-162
-
-
Gale Jr., M.J.1
Korth, M.J.2
Katze, M.G.3
-
44
-
-
0036067898
-
An altered cellular response to interferon and upregulation of interleukin-8 induced by the hepatitis C viral protein NS5A uncovered by microarray analysis
-
GIRARD S, SHALHOUB P, LESCURE P et al.: An altered cellular response to interferon and upregulation of interleukin-8 induced by the hepatitis C viral protein NS5A uncovered by microarray analysis. Virology (2002) 295(2):272-283.
-
(2002)
Virology
, vol.295
, Issue.2
, pp. 272-283
-
-
Girard, S.1
Shalhoub, P.2
Lescure, P.3
-
45
-
-
0034532953
-
The broad spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen
-
CROTTY S, MAAG D, ARNOLD JJ et al.: The broad spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen. Nat. Med. (2000) 6(12):1375-1379.
-
(2000)
Nat. Med.
, vol.6
, Issue.12
, pp. 1375-1379
-
-
Crotty, S.1
Maag, D.2
Arnold, J.J.3
-
46
-
-
0035824671
-
Hepatitis C virus RNA-dependent RNA polymerase (NS5B) as a mediator of the antiviral activity of ribavirin
-
MAAG D, CASTRO C, HONG Z et al.: Hepatitis C virus RNA-dependent RNA polymerase (NS5B) as a mediator of the antiviral activity of ribavirin. J. Biol. Chem. (2001) 276(49):46094-46098.
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.49
, pp. 46094-46098
-
-
Maag, D.1
Castro, C.2
Hong, Z.3
-
47
-
-
0036237981
-
Crystal structure of an RNA tertiary domain essential to HCV IRES-mediated translation initiation
-
KIEFF JS, ZHOU K, GRECH A et al.: Crystal structure of an RNA tertiary domain essential to HCV IRES-mediated translation initiation. Nat. Struct. Biol. (2002) 9(5):370-374.
-
(2002)
Nat. Struct. Biol.
, vol.9
, Issue.5
, pp. 370-374
-
-
Kieff, J.S.1
Zhou, K.2
Grech, A.3
-
48
-
-
0033992656
-
Internal ribosome entry site-mediated translation in hepatitis C virus replication
-
RIJNBRAND RC, LEMON SM: Internal ribosome entry site-mediated translation in hepatitis C virus replication. Curr. Top. Microbiol. Immunol. (2000) 242:85-116.
-
(2000)
Curr. Top. Microbiol. Immunol.
, vol.242
, pp. 85-116
-
-
Rijnbrand, R.C.1
Lemon, S.M.2
-
49
-
-
0029949695
-
Stability of a stem-loop involving the initiator AUG controls the efficiency of internal initiation of translation on hepatitis C virus RNA
-
HONDA M, BROWN EA, LEMON SM: Stability of a stem-loop involving the initiator AUG controls the efficiency of internal initiation of translation on hepatitis C virus RNA. RNA (1996) 2(10):955-968.
-
(1996)
RNA
, vol.2
, Issue.10
, pp. 955-968
-
-
Honda, M.1
Brown, E.A.2
Lemon, S.M.3
-
50
-
-
0030219426
-
Structural requirements for initiation of translation by internal ribosome entry within genome-length hepatitis C virus RNA
-
HONDA M, PING LH, RIJNBRAND RC et al.: Structural requirements for initiation of translation by internal ribosome entry within genome-length hepatitis C virus RNA. Virology (1996) 222(1):31-42.
-
(1996)
Virology
, vol.222
, Issue.1
, pp. 31-42
-
-
Honda, M.1
Ping, L.H.2
Rijnbrand, R.C.3
-
51
-
-
0030246114
-
Genetic organization and diversity of the 3′ non-coding region of the hepatitis C virus genome
-
YAMADA N, TANIHARA K, TAKADA A et al.: Genetic organization and diversity of the 3′ non-coding region of the hepatitis C virus genome. Virology (1996) 223(1):255-261.
-
(1996)
Virology
, vol.223
, Issue.1
, pp. 255-261
-
-
Yamada, N.1
Tanihara, K.2
Takada, A.3
-
52
-
-
0029156656
-
Specific inhibition of hepatitis C viral gene expression by antisense phosphorothioate oligodeoxynucleotides
-
ALT M, RENZ R, HOFSCHNEIDER PH, PAUMGARTNER G, CASELMANN WH: Specific inhibition of hepatitis C viral gene expression by antisense phosphorothioate oligodeoxynucleotides. Hepatology (1995) 22(3):707-717.
-
(1995)
Hepatology
, vol.22
, Issue.3
, pp. 707-717
-
-
Alt, M.1
Renz, R.2
Hofschneider, P.H.3
Paumgartner, G.4
Caselmann, W.H.5
-
53
-
-
0032882628
-
Comparative inhibitory potential of differently modified antisense oligodeoxynucleotides on hepatitis C virus translation
-
ALT M, EISENHARDT S, SERWE M, RENZ R, ENGELS JW, CASELMANN WH: Comparative inhibitory potential of differently modified antisense oligodeoxynucleotides on hepatitis C virus translation. Eur. J. Clin. Invest. (1999) 29(10):868-876.
-
(1999)
Eur. J. Clin. Invest.
, vol.29
, Issue.10
, pp. 868-876
-
-
Alt, M.1
Eisenhardt, S.2
Serwe, M.3
Renz, R.4
Engels, J.W.5
Caselmann, W.H.6
-
54
-
-
0036545533
-
The hepatitis C virus internal ribosome-entry site: A new target for antiviral research
-
GALLEGO J, VARANI G: The hepatitis C virus internal ribosome-entry site: a new target for antiviral research. Biochem. Soc. Trans. (2002) 30(2):140-145.
-
(2002)
Biochem. Soc. Trans.
, vol.30
, Issue.2
, pp. 140-145
-
-
Gallego, J.1
Varani, G.2
-
55
-
-
0032870465
-
Immune selection and generic sequence variation in core and envelope regions of hepatitis C virus
-
CHRISTIE JM, CHAPEL H, CHAPMAN RW, ROSENBERG WM: Immune selection and generic sequence variation in core and envelope regions of hepatitis C virus. Hepatology (1999) 30(4):1037-1044.
-
(1999)
Hepatology
, vol.30
, Issue.4
, pp. 1037-1044
-
-
Christie, J.M.1
Chapel, H.2
Chapman, R.W.3
Rosenberg, W.M.4
-
56
-
-
0034885745
-
Studies of hepatitis C virus in chimpanzees and their importance for vaccine development
-
BUKH J, FORNS X, EMERSON SU, PURCELL RH: Studies of hepatitis C virus in chimpanzees and their importance for vaccine development. Intervirology (2001) 44(2-3):132-142.
-
(2001)
Intervirology
, vol.44
, Issue.2-3
, pp. 132-142
-
-
Bukh, J.1
Forns, X.2
Emerson, S.U.3
Purcell, R.H.4
-
57
-
-
0033063225
-
An infectious molecular done of a Japanese genotype 1b hepatitis C virus
-
BEARD MR, ABELL G, HONDA M et al.: An infectious molecular done of a Japanese genotype 1b hepatitis C virus. Hepatology (1999) 30(1):316-324.
-
(1999)
Hepatology
, vol.30
, Issue.1
, pp. 316-324
-
-
Beard, M.R.1
Abell, G.2
Honda, M.3
-
58
-
-
0030864915
-
Transmission of hepatitis C by intrahepatic inoculation with transcribed RNA
-
(5325)
-
KOLYKHALOV AA, AGAPOV EV, BLIGHT KJ, MIHALIK K, FEINSTONE SM, RICE CM: Transmission of hepatitis C by intrahepatic inoculation with transcribed RNA. Science (1997) 277(5325):570-574.
-
(1997)
Science
, vol.277
, pp. 570-574
-
-
Kolykhalov, A.A.1
Agapov, E.V.2
Blight, K.J.3
Mihalik, K.4
Feinstone, S.M.5
Rice, C.M.6
-
59
-
-
0030740520
-
Transcripts from a single full-length cDNA done of hepatitis C virus are infectious when directly transfected into the liver of a chimpanzee
-
YANAGI M, PURCELL RH, EMERSON SU, BUKH J: Transcripts from a single full-length cDNA done of hepatitis C virus are infectious when directly transfected into the liver of a chimpanzee. Proc. Natl. Acad. Sci. USA (1997) 94(16):8738-8743.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, Issue.16
, pp. 8738-8743
-
-
Yanagi, M.1
Purcell, R.H.2
Emerson, S.U.3
Bukh, J.4
-
60
-
-
0034877411
-
Novel cell culture systems for the hepatitis C virus
-
BARTENSCHLAGER R, LOHMANN V: Novel cell culture systems for the hepatitis C virus. Antiviral Res. (2001) 52(1):1-17.
-
(2001)
Antiviral Res.
, vol.52
, Issue.1
, pp. 1-17
-
-
Bartenschlager, R.1
Lohmann, V.2
-
62
-
-
0345188811
-
Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line
-
(5424)
-
LOHMANN V, KORNER F, KOCH J, HERIAN U, THEILMANN L, BARTENSCHLAGER R: Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line. Science (1999) 285(5424):110-113.
-
(1999)
Science
, vol.285
, pp. 110-113
-
-
Lohmann, V.1
Korner, F.2
Koch, J.3
Herian, U.4
Theilmann, L.5
Bartenschlager, R.6
-
63
-
-
0031807790
-
Hepatitis C virus persistence in human hematopoietic cells injected into SCID mice
-
BRONOWICKI JP, LORIOT MA, THIERS V, GRIGNON Y, ZIGNEGO AL, BRECHOT C: Hepatitis C virus persistence in human hematopoietic cells injected into SCID mice. Hepatology (1998) 28(1):211-218.
-
(1998)
Hepatology
, vol.28
, Issue.1
, pp. 211-218
-
-
Bronowicki, J.P.1
Loriot, M.A.2
Thiers, V.3
Grignon, Y.4
Zignego, A.L.5
Brechot, C.6
-
64
-
-
0037621934
-
Expression of hepatitis C virus proteins inhibits interferon-α signalling in the liver of transgenic mice
-
BLINDENBACHER A, DUONG FH, HUNZIKER L et al.: Expression of hepatitis C virus proteins inhibits interferon-α signalling in the liver of transgenic mice. Gastroenterology (2003) 124(5):1465-1475.
-
(2003)
Gastroenterology
, vol.124
, Issue.5
, pp. 1465-1475
-
-
Blindenbacher, A.1
Duong, F.H.2
Hunziker, L.3
-
65
-
-
0030940874
-
Transgenic expression of hepatitis C virus structural proteins in the mouse
-
KAWAMURA T, FURUSAKA A, KOZIEL MJ et al.: Transgenic expression of hepatitis C virus structural proteins in the mouse. Hepatology (1997) 25(4):1014-1021.
-
(1997)
Hepatology
, vol.25
, Issue.4
, pp. 1014-1021
-
-
Kawamura, T.1
Furusaka, A.2
Koziel, M.J.3
-
66
-
-
0034892127
-
A mouse model for hepatitis C virus infection?
-
FAUSTO N: A mouse model for hepatitis C virus infection? Nat. Med. (2001) 7(8):890-891.
-
(2001)
Nat. Med.
, vol.7
, Issue.8
, pp. 890-891
-
-
Fausto, N.1
-
67
-
-
0036829751
-
Optimal therapy of hepatitis C
-
DI BISCEGLIE AM, HOOFNAGLE JH: Optimal therapy of hepatitis C. Hepatology (2002) 36(5Suppl.1):S121-S127.
-
(2002)
Hepatology
, vol.36
, Issue.5 SUPPL. 1
-
-
Di Bisceglie, A.M.1
Hoofnagle, J.H.2
-
69
-
-
0036830350
-
Future therapy of hepatitis C
-
MCHUTCHISON JG, PATEL K: Future therapy of hepatitis C. Hepatology (2002) 36(5 Suppl-1):S245-S252.
-
(2002)
Hepatology
, vol.36
, Issue.5 SUPPL. 1
-
-
Mchutchison, J.G.1
Patel, K.2
-
70
-
-
0036091729
-
Management issues in chronic viral hepatitis: Hepatitis C
-
SIEVERT W: Management issues in chronic viral hepatitis: hepatitis C. J. Gastroenterol. Hepatol. (2002) 17(4):415-422.
-
(2002)
J. Gastroenterol. Hepatol.
, vol.17
, Issue.4
, pp. 415-422
-
-
Sievert, W.1
-
71
-
-
0036240477
-
Mechanism of action of ribavirin in the combination treatment of chronic HCV infection
-
LAU JY, TAM RC, LIANG TJ, HONG Z: Mechanism of action of ribavirin in the combination treatment of chronic HCV infection. Hepatology (2002) 35(5):1002-1009.
-
(2002)
Hepatology
, vol.35
, Issue.5
, pp. 1002-1009
-
-
Lau, J.Y.1
Tam, R.C.2
Liang, T.J.3
Hong, Z.4
-
72
-
-
85047692907
-
The effect of ribavirin and IMPDH inhibitors on hepatitis C virus subgenomic replicon RNA
-
ZHOU S, LIU R, RAROUDY BM, MALCOLM BA, REYES GR: The effect of ribavirin and IMPDH inhibitors on hepatitis C virus subgenomic replicon RNA. Virology (2003) 310(2):333-342.
-
(2003)
Virology
, vol.310
, Issue.2
, pp. 333-342
-
-
Zhou, S.1
Liu, R.2
Raroudy, B.M.3
Malcolm, B.A.4
Reyes, G.R.5
-
73
-
-
0000571975
-
Viramidine, a prodrug of ribavirin, demonstrated superior liver-targeting properties and much improved toxicity profile in cynomolgus monkey studies
-
Abstract
-
LIN CC, LUU K, LOURENCO D, YEH LT: Viramidine, a prodrug of ribavirin, demonstrated superior liver-targeting properties and much improved toxicity profile in cynomolgus monkey studies. Hepatology (2001) 34(Suppl.):453a. Abstract.
-
(2001)
Hepatology
, vol.34
, Issue.SUPPL.
-
-
Lin, C.C.1
Luu, K.2
Lourenco, D.3
Yeh, L.T.4
-
74
-
-
0242442326
-
Determination of viramidine/ribavirin in human RBC following single oral dosing of viramidine in a Phase I Study
-
YEH L, FANG JW, NGUYEN M et al.: Determination of viramidine/ribavirin in human RBC following single oral dosing of viramidine in a Phase I Study. Hepatology (2002) 36(4):345A.
-
(2002)
Hepatology
, vol.36
, Issue.4
-
-
Yeh, L.1
Fang, J.W.2
Nguyen, M.3
-
75
-
-
12244305605
-
Ribonucleoside analogue that blocks replication of bovine viral diarrhea and hepatitis C viruses in culture
-
STUYVER LJ, WHITAKER T, MCBRAYER TR et al.: Ribonucleoside analogue that blocks replication of bovine viral diarrhea and hepatitis C viruses in culture. Antimicrob. Agents Chemother. (2003) 47(1):244-254.
-
(2003)
Antimicrob. Agents Chemother.
, vol.47
, Issue.1
, pp. 244-254
-
-
Stuyver, L.J.1
Whitaker, T.2
Mcbrayer, T.R.3
-
76
-
-
0003072207
-
Therapies for hepatitis C infection: Targeting the non-structural proteins of HCV
-
BEAULIEU PL, LLINAS-BRUNET M: Therapies for hepatitis C infection: targeting the non-structural proteins of HCV. Curr Med. Chem. (2002) 1:163-176.
-
(2002)
Curr. Med. Chem.
, vol.1
, pp. 163-176
-
-
Beaulieu, P.L.1
Llinas-Brunet, M.2
-
77
-
-
0034916847
-
Recent advances in the discovery of small molecule therapies for HCV
-
MYLES DC: Recent advances in the discovery of small molecule therapies for HCV. Curr. Opin. Drug Discov. Devel. (2001) 4(4):411-416.
-
(2001)
Curr. Opin. Drug Discov. Devel.
, vol.4
, Issue.4
, pp. 411-416
-
-
Myles, D.C.1
-
78
-
-
0037315296
-
Recent developments in the discovery of hepatitis C virus serine protease inhibitors - Towards a new class of antiviral agents?
-
NARJES F, KOCH U, STEINKUHLER C: Recent developments in the discovery of hepatitis C virus serine protease inhibitors - towards a new class of antiviral agents? Expert Opin. Investig. Drugs. (2003) 12(2):153-163.
-
(2003)
Expert Opin. Investig. Drugs.
, vol.12
, Issue.2
, pp. 153-163
-
-
Narjes, F.1
Koch, U.2
Steinkuhler, C.3
-
79
-
-
0036149695
-
A prospective randomized trial of mycophenolate mofetil in liver transplant recipients with hepatitis C
-
JAIN A, KASHYAP R, DEMETRIS AJ, EGHSTESAD B, POKHARNA R, FUNG JJ: A prospective randomized trial of mycophenolate mofetil in liver transplant recipients with hepatitis C. Liver Transpl. (2002) 8(1):40-46.
-
(2002)
Liver Transpl.
, vol.8
, Issue.1
, pp. 40-46
-
-
Jain, A.1
Kashyap, R.2
Demetris, A.J.3
Eghstesad, B.4
Pokharna, R.5
Fung, J.J.6
-
80
-
-
0037232440
-
Lack of antiviral effect of a short course of mycophenolate mofetil in patients with chronic hepatitis C virus infection
-
FIRPI RJ, NELSON DP, DAVIS GL: Lack of antiviral effect of a short course of mycophenolate mofetil in patients with chronic hepatitis C virus infection. Liver Transpl. (2003) 9(1):57-61.
-
(2003)
Liver Transpl.
, vol.9
, Issue.1
, pp. 57-61
-
-
Firpi, R.J.1
Nelson, D.P.2
Davis, G.L.3
-
81
-
-
0036893764
-
Mycophenolate mofetil in combination with recombinant interferon-α-2a in interferon-nonresponder patients with chronic hepatitis C
-
CORNBERG M, HINRICHSEN H, TEUBER G et al.: Mycophenolate mofetil in combination with recombinant interferon-α-2a in interferon-nonresponder patients with chronic hepatitis C. J. Hepatol. (2002) 37(6):843-847.
-
(2002)
J. Hepatol.
, vol.37
, Issue.6
, pp. 843-847
-
-
Cornberg, M.1
Hinrichsen, H.2
Teuber, G.3
-
82
-
-
0034102651
-
Broad spectrum antiviral activity of the IMP dehydrogenase inhibitor VX-497: A comparison with ribavirin and demonstration of antiviral additivity with a interferon
-
MARKLAND W, MCQUAID TJ, JAIN J, KWONG AD: Broad spectrum antiviral activity of the IMP dehydrogenase inhibitor VX-497: a comparison with ribavirin and demonstration of antiviral additivity with a interferon. Antimicrob. Agents Chemother. (2000) 44(4):859-866.
-
(2000)
Antimicrob. Agents Chemother.
, vol.44
, Issue.4
, pp. 859-866
-
-
Markland, W.1
Mcquaid, T.J.2
Jain, J.3
Kwong, A.D.4
-
83
-
-
0036835590
-
Hepatitis C therapeutics: Current status and emerging strategies
-
TAN SL, PAUSE A, SHI Y, SONENBERG N: Hepatitis C therapeutics: current status and emerging strategies. Nat. Rev. Drug Discov. (2002) 1(11):867-881.
-
(2002)
Nat. Rev. Drug Discov.
, vol.1
, Issue.11
, pp. 867-881
-
-
Tan, S.L.1
Pause, A.2
Shi, Y.3
Sonenberg, N.4
-
84
-
-
0035027046
-
Emerging therapies for hepatitis C virus infection
-
DYMOCK BW: Emerging therapies for hepatitis C virus infection. Emerging Drugs (2001) 6(1):13-42.
-
(2001)
Emerging Drugs
, vol.6
, Issue.1
, pp. 13-42
-
-
Dymock, B.W.1
-
85
-
-
0035923585
-
Host cell factor requirement for hepatitis C virus enzyme maturation
-
WAXMAN L, WHITNEY M, POLLOK BA, KUO LC, DARKE PL: Host cell factor requirement for hepatitis C virus enzyme maturation. Proc. Natl. Acad. Sci. USA (2001) 98(24):13931-13935.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, Issue.24
, pp. 13931-13935
-
-
Waxman, L.1
Whitney, M.2
Pollok, B.A.3
Kuo, L.C.4
Darke, P.L.5
-
86
-
-
0031693703
-
The Hsp90 complex - A super-chaperone machine as a novel drug target
-
SCHEIBEL T, BUCHNER J: The Hsp90 complex - a super-chaperone machine as a novel drug target. Biochem. Pharmacol. (1998) 56(6):675-682.
-
(1998)
Biochem. Pharmacol.
, vol.56
, Issue.6
, pp. 675-682
-
-
Scheibel, T.1
Buchner, J.2
-
87
-
-
0035176758
-
The Hsp90 chaperone as a promising drug target
-
PIPER PW: The Hsp90 chaperone as a promising drug target. Curr. Opin. Investig. Drugs (2001) 2(11):1606-1610.
-
(2001)
Curr. Opin. Investig. Drugs
, vol.2
, Issue.11
, pp. 1606-1610
-
-
Piper, P.W.1
-
88
-
-
0037241732
-
Molecular chaperone Hsp90 as a novel target for cancer chemotherapy
-
Japanese
-
MIYATA Y: [Molecular chaperone Hsp90 as a novel target for cancer chemotherapy]. Nippon Yakurigaku Zasshi (2003) 121(1):33-42. Japanese.
-
(2003)
Nippon Yakurigaku Zasshi
, vol.121
, Issue.1
, pp. 33-42
-
-
Miyata, Y.1
-
89
-
-
0034693228
-
Hsp90 chaperone activity requires the full-length protein and interaction among its multiple domains
-
JOHNSON BD, CHADLI A, FELTS SJ, BOUHOUCHE I, CATELLI MG, TOFT DO: Hsp90 chaperone activity requires the full-length protein and interaction among its multiple domains. J. Biol. Chem. (2000) 275(42):32499-32507.
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.42
, pp. 32499-32507
-
-
Johnson, B.D.1
Chadli, A.2
Felts, S.J.3
Bouhouche, I.4
Catelli, M.G.5
Toft, D.O.6
-
90
-
-
13144266673
-
An inhibitor of HIV-1 protease modulates proteasome activity, antigen presentation and T cell responses
-
ANDRE P, GROETTRUP M, KLENERMAN P et al.: An inhibitor of HIV-1 protease modulates proteasome activity, antigen presentation and T cell responses. Proc. Natl. Acad. Sci. USA (1998) 95(22):13120-13124.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, Issue.22
, pp. 13120-13124
-
-
Andre, P.1
Groettrup, M.2
Klenerman, P.3
-
91
-
-
0033496260
-
Sustained disappearance of hepatitis C viremia in patients receiving protease inhibitor treatment for human immunodeficiency virus infection
-
FIALAIRE P, PAYAN C, VITOUR D et al.: Sustained disappearance of hepatitis C viremia in patients receiving protease inhibitor treatment for human immunodeficiency virus infection. J. Infect. Dis. (1999) 180(2):574-575.
-
(1999)
J. Infect. Dis.
, vol.180
, Issue.2
, pp. 574-575
-
-
Fialaire, P.1
Payan, C.2
Vitour, D.3
-
92
-
-
0032480896
-
Hepatitis C virus-associated hepatitis following treatment of HIV-infected patients with HIV protease inhibitors: An immune restoration disease?
-
JOHN M, FLEXMAN J, FRENCH MA: Hepatitis C virus-associated hepatitis following treatment of HIV-infected patients with HIV protease inhibitors: an immune restoration disease? Aids (1998) 12(17):2289-2293.
-
(1998)
Aids
, vol.12
, Issue.17
, pp. 2289-2293
-
-
John, M.1
Flexman, J.2
French, M.A.3
-
93
-
-
0035139969
-
Human immunodeficiency virus (HIV) protease inhibitors have no effect on hepatitis C virus (HCV) serum levels of HIV-HCV co-infected patients
-
MATSIOTA-BERNARD P, VRIONI G, ONODY C, BERNARD L, DE TRUCHIS P, PERONNE C: Human immunodeficiency virus (HIV) protease inhibitors have no effect on hepatitis C virus (HCV) serum levels of HIV-HCV co-infected patients. Int. J. Antimicrob. Agents (2001) 17(2):155-157.
-
(2001)
Int. J. Antimicrob. Agents
, vol.17
, Issue.2
, pp. 155-157
-
-
Matsiota-Bernard, P.1
Vrioni, G.2
Onody, C.3
Bernard, L.4
De Truchis, P.5
Peronne, C.6
-
94
-
-
0036569989
-
Hepatotoxicity associated with antiretroviral therapy containing dual versus single protease inhibitors in individuals coinfected with hepatitis C virus and human immunodeficiency virus
-
COOPER CL, PARBHAKAR MA, ANGEL JB: Hepatotoxicity associated with antiretroviral therapy containing dual versus single protease inhibitors in individuals coinfected with hepatitis C virus and human immunodeficiency virus. Clin. Infect. Dis. (2002) 34(9):1259-1263.
-
(2002)
Clin. Infect. Dis.
, vol.34
, Issue.9
, pp. 1259-1263
-
-
Cooper, C.L.1
Parbhakar, M.A.2
Angel, J.B.3
-
95
-
-
0034425846
-
Hepatitis B or hepatitis C virus infection is a risk factor for severe hepatic cytolysis after initiation of a protease inhibitor-containing antiretroviral regimen in human immunodeficiency virus-infected patients
-
The APROCO Study Group
-
SAVES M, RAFFI F, CLEVENBERGH P et al.: Hepatitis B or hepatitis C virus infection is a risk factor for severe hepatic cytolysis after initiation of a protease inhibitor-containing antiretroviral regimen in human immunodeficiency virus-infected patients. The APROCO Study Group. Antimicrob. Agents Chemother. (2000) 44(12):3451-3455.
-
(2000)
Antimicrob. Agents Chemother.
, vol.44
, Issue.12
, pp. 3451-3455
-
-
Saves, M.1
Raffi, F.2
Clevenbergh, P.3
-
96
-
-
0036924593
-
Cyclin-dependent kinases as cellular targets for antiviral drugs
-
SCHANG LM: Cyclin-dependent kinases as cellular targets for antiviral drugs. J. Antimicrob. Chemother. (2002) 50(6):779-792.
-
(2002)
J. Antimicrob. Chemother.
, vol.50
, Issue.6
, pp. 779-792
-
-
Schang, L.M.1
-
97
-
-
0036310685
-
Pharmacological cyclin-dependent kinase inhibitors inhibit replication of wild type and drug-resistant strains of herpes simplex virus and human immunodeficiency virus Type 1 by targeting cellular, not viral, proteins
-
SCHANG LM, BANTLY A, KNOCKAERT M et al.: Pharmacological cyclin-dependent kinase inhibitors inhibit replication of wild type and drug-resistant strains of herpes simplex virus and human immunodeficiency virus Type 1 by targeting cellular, not viral, proteins. J. Virol. (2002) 76(15):7874-7882.
-
(2002)
J. Virol.
, vol.76
, Issue.15
, pp. 7874-7882
-
-
Schang, L.M.1
Bantly, A.2
Knockaert, M.3
-
98
-
-
0033763593
-
Recent advances in prevention and treatment of hepatitis C virus infections
-
WANG QM, HEINZ BA: Recent advances in prevention and treatment of hepatitis C virus infections. Prog. Drug Res. (2000) 55:1-32.
-
(2000)
Prog. Drug Res.
, vol.55
, pp. 1-32
-
-
Wang, Q.M.1
Heinz, B.A.2
-
99
-
-
0037648871
-
Design of β-turn based therapeutic agents
-
KEE KS, JOIS SD: Design of β-turn based therapeutic agents. Curr. Pharm. Des. (2003) 9(15):1209-1224.
-
(2003)
Curr. Pharm. Des.
, vol.9
, Issue.15
, pp. 1209-1224
-
-
Kee, K.S.1
Jois, S.D.2
-
100
-
-
0035824669
-
In vitro characterization of a purified NS2/3 protease variant of hepatitis C virus
-
THIBEAULT D, MAURICE R, PILOTE L et al.: In vitro characterization of a purified NS2/3 protease variant of hepatitis C virus. J. Biol. Chem. (2001) 276(49):46678-46684.
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.49
, pp. 46678-46684
-
-
Thibeault, D.1
Maurice, R.2
Pilote, L.3
-
101
-
-
0038621557
-
Hepatotoxicity associated with antiretroviral therapy containing HIV-1 protease inhibitors
-
SULKOWSKI MS: Hepatotoxicity associated with antiretroviral therapy containing HIV-1 protease inhibitors. Semin. Liver Dis. (2003) 23(2):183-194.
-
(2003)
Semin. Liver Dis.
, vol.23
, Issue.2
, pp. 183-194
-
-
Sulkowski, M.S.1
-
102
-
-
0037197701
-
Prime site binding inhibitors of a serine protease: NS3/4A of hepatitis C virus
-
INGALLINELLA P, FATTORI D, ALTAMURA S et al.: Prime site binding inhibitors of a serine protease: NS3/4A of hepatitis C virus. Biochemistry (2002) 41(17):5483-5492.
-
(2002)
Biochemistry
, vol.41
, Issue.17
, pp. 5483-5492
-
-
Ingallinella, P.1
Fattori, D.2
Altamura, S.3
-
103
-
-
0037664057
-
The discovery of BILN-2061 - An orally bioavailable small molecule inhibitor of the HCV serine protease and a promising antiviral for the treatment of hepatits C
-
LAMARRE D, BAILEY M, BOLGER G et al.: The discovery of BILN-2061 - an orally bioavailable small molecule inhibitor of the HCV serine protease and a promising antiviral for the treatment of hepatits C. Hepatology (2002) 36(4):279A
-
(2002)
Hepatology
, vol.36
, Issue.4
-
-
Lamarre, D.1
Bailey, M.2
Bolger, G.3
-
104
-
-
0029979731
-
A hitchhiker's guide to antisense and non-antisense biochemical pathways
-
BRANCH AD: A hitchhiker's guide to antisense and non-antisense biochemical pathways. Hepatology (1996) 24(6):1517-1529.
-
(1996)
Hepatology
, vol.24
, Issue.6
, pp. 1517-1529
-
-
Branch, A.D.1
-
105
-
-
0033793681
-
Design, delivery and efficacy testing of therapeutic nucleic acidsused to inhibit hepatitis C virus gene expression in vitro and in vivo
-
CASELMANN WH, SERWE M, LEHMANN T et al.: Design, delivery and efficacy testing of therapeutic nucleic acidsused to inhibit hepatitis C virus gene expression in vitro and in vivo. World J. Gastroenterol. (2000) 6(5):626-629.
-
(2000)
World J. Gastroenterol.
, vol.6
, Issue.5
, pp. 626-629
-
-
Caselmann, W.H.1
Serwe, M.2
Lehmann, T.3
-
106
-
-
0034851905
-
Design and properties of hepatitis C virus antisense oligonucleotides for liver specific drug targeting
-
LEHMANN TJ, SERWE M, CASELMANN WH et al.: Design and properties of hepatitis C virus antisense oligonucleotides for liver specific drug targeting. Nucleosides Nucleotides Nucleic Acids (2001) 20(4-7):1343-1346.
-
(2001)
Nucleosides Nucleotides Nucleic Acids
, vol.20
, Issue.4-7
, pp. 1343-1346
-
-
Lehmann, T.J.1
Serwe, M.2
Caselmann, W.H.3
-
107
-
-
0037440001
-
Antisense oligonucleotides targeted to the domain IIId of the hepatitis C virus IRES compete with 40S ribosomal subunit binding and prevent in vitro translation
-
TALLET-LOPEZ B, ALDAZ-CARROLL L, CHABAS S, DAUSSE E, STAEDEL C, TOULME JJ: Antisense oligonucleotides targeted to the domain IIId of the hepatitis C virus IRES compete with 40S ribosomal subunit binding and prevent in vitro translation. Nucleic Acids Res. (2003) 31(2):734-742.
-
(2003)
Nucleic Acids Res.
, vol.31
, Issue.2
, pp. 734-742
-
-
Tallet-Lopez, B.1
Aldaz-Carroll, L.2
Chabas, S.3
Dausse, E.4
Staedel, C.5
Toulme, J.J.6
-
108
-
-
0036130493
-
Cloning and molecular characterization of human high affinity antibody fragments against hepatitis C virus NS3 helicase
-
TESSMANN K, ERHARDT A, HAUSSINGER D et al.: Cloning and molecular characterization of human high affinity antibody fragments against hepatitis C virus NS3 helicase. J. Virol. Methods (2002) 103(1):75-88.
-
(2002)
J. Virol. Methods
, vol.103
, Issue.1
, pp. 75-88
-
-
Tessmann, K.1
Erhardt, A.2
Haussinger, D.3
-
109
-
-
0035214935
-
Inhibition of hepatitis C virus NS3 function by antisense oligodeoxynucleotides and protease inhibitor
-
HEINTGES T, ENCKE J, ZU PUTLITZ J et al.: Inhibition of hepatitis C virus NS3 function by antisense oligodeoxynucleotides and protease inhibitor. J. Med. Virol. (2001) 65(4):671-680.
-
(2001)
J. Med. Virol.
, vol.65
, Issue.4
, pp. 671-680
-
-
Heintges, T.1
Encke, J.2
Zu Putlitz, J.3
-
110
-
-
0036339891
-
Downregulation of a gene-expression by an antisense BNA oligonucleotide
-
Japanese
-
IMANISHI T, OBIKA S: [Downregulation of a gene-expression by an antisense BNA oligonucleotide]. Nippon Yakurigaku Zasshi (2002) 120(2):85-90. Japanese.
-
(2002)
Nippon Yakurigaku Zasshi
, vol.120
, Issue.2
, pp. 85-90
-
-
Imanishi, T.1
Obika, S.2
-
111
-
-
0032995650
-
Antisense oligonucleotide inhibition of hepatitis C virus (HCV) gene expression in livers of mice infected with an HCV-vaccinia virus recombinant
-
ZHANG H, HANECAK R, BROWN-DRIVER V et al.: Antisense oligonucleotide inhibition of hepatitis C virus (HCV) gene expression in livers of mice infected with an HCV-vaccinia virus recombinant. Antimicrob. Agents Chemother. (1999) 43(2):347-353.
-
(1999)
Antimicrob. Agents Chemother.
, vol.43
, Issue.2
, pp. 347-353
-
-
Zhang, H.1
Hanecak, R.2
Brown-Driver, V.3
-
112
-
-
0035553604
-
Enhanced antiviral effect in cell culture of Type 1 interferon and ribozymes targeting HCV RNA
-
MACEJAK DG, JENSEN K L, PAVCO PA et al.: Enhanced antiviral effect in cell culture of Type 1 interferon and ribozymes targeting HCV RNA. J. Viral Hepat. (2001) 8(6):400-405.
-
(2001)
J. Viral Hepat.
, vol.8
, Issue.6
, pp. 400-405
-
-
Macejak, D.G.1
Jensen, K.L.2
Pavco, P.A.3
-
113
-
-
0033848988
-
Pharmacokinetics and tissue distribution of a ribozyme directed against hepatitis C virus RNA following subcutaneous or intravenous administration in mice
-
LEE PA, BLATT LM, BLANCHARD KS et al.: Pharmacokinetics and tissue distribution of a ribozyme directed against hepatitis C virus RNA following subcutaneous or intravenous administration in mice. Hepatology (2000) 32(3):640-646.
-
(2000)
Hepatology
, vol.32
, Issue.3
, pp. 640-646
-
-
Lee, P.A.1
Blatt, L.M.2
Blanchard, K.S.3
-
114
-
-
0033560314
-
Aptamers: A novel approach to intervention studies and development of novel therapeutic approaches
-
OSTENDORF T, FLOEGE J: Aptamers: a novel approach to intervention studies and development of novel therapeutic approaches. Med. Klin. (1999) 94(4):219-223.
-
(1999)
Med. Klin.
, vol.94
, Issue.4
, pp. 219-223
-
-
Ostendorf, T.1
Floege, J.2
-
115
-
-
0032860385
-
Aptamers: An emerging class of molecules that rival antibodies in diagnostics
-
JAYASENA SD: Aptamers: an emerging class of molecules that rival antibodies in diagnostics. Clin. Chem. (1999) 45(9):1628-1650.
-
(1999)
Clin. Chem.
, vol.45
, Issue.9
, pp. 1628-1650
-
-
Jayasena, S.D.1
-
116
-
-
0242610636
-
A Phase II 12-week study of ISIS-14803, an antisense inhibitor of HCV for the treatment of chronic hepatitis C
-
GORDON SC, BACON BR, JACOBSON IM et al.: A Phase II 12-week study of ISIS-14803, an antisense inhibitor of HCV for the treatment of chronic hepatitis C. Hepatology (2002) 36(4):362A.
-
(2002)
Hepatology
, vol.36
, Issue.4
-
-
Gordon, S.C.1
Bacon, B.R.2
Jacobson, I.M.3
-
117
-
-
0242694722
-
Preliminary analysis of a Phase II study of heptazyme nuclease-resistent ribozyme targeting hepatitis C virus (HCV) RNA
-
TONG M, SCHIFF E, JENSEN DM et al.: Preliminary analysis of a Phase II study of heptazyme nuclease-resistent ribozyme targeting hepatitis C virus (HCV) RNA. Hepatology (2002) 36(4):360A.
-
(2002)
Hepatology
, vol.36
, Issue.4
-
-
Tong, M.1
Schiff, E.2
Jensen, D.M.3
-
118
-
-
0037444390
-
Identification of RNA ligands that bind hepatitis C virus polymerase selectively and inhibit its RNA synthesis from the natural viral RNA templates
-
VO NV, OH JW, LAI MM: Identification of RNA ligands that bind hepatitis C virus polymerase selectively and inhibit its RNA synthesis from the natural viral RNA templates. Virology (2003) 307(2):301-316.
-
(2003)
Virology
, vol.307
, Issue.2
, pp. 301-316
-
-
Vo, N.V.1
Oh, J.W.2
Lai, M.M.3
-
119
-
-
0037390892
-
Inhibition of HCV NS3 protease by RNA aptamers in cells
-
NISHIKAWA F, KAKIUCHI N, FUNAJI K, FUKUDA K, SEKIYA S, NISHIKAWA S: Inhibition of HCV NS3 protease by RNA aptamers in cells. Nucleic Acids Res. (2003) 31(7):1935-1943.
-
(2003)
Nucleic Acids Res.
, vol.31
, Issue.7
, pp. 1935-1943
-
-
Nishikawa, F.1
Kakiuchi, N.2
Funaji, K.3
Fukuda, K.4
Sekiya, S.5
Nishikawa, S.6
-
120
-
-
0036675117
-
Cell membranes as barriers for the use of antisense therapeutic agents
-
JAASKELAINEN I, URTTI A: Cell membranes as barriers for the use of antisense therapeutic agents. Mini Rev. Med. Chem. (2002) 2(4):307-318.
-
(2002)
Mini Rev. Med. Chem.
, vol.2
, Issue.4
, pp. 307-318
-
-
Jaaskelainen, I.1
Urtti, A.2
-
121
-
-
0035709608
-
Regulated and prolonged expression of mIFN-α in immunocompetent mice mediated by a helper-dependent adenovirus vector
-
AURISICCHIO L, BUJARD H, HILLEN W et al.: Regulated and prolonged expression of mIFN-α in immunocompetent mice mediated by a helper-dependent adenovirus vector. Gene Ther. (2001) 8(24):1817-1825.
-
(2001)
Gene Ther.
, vol.8
, Issue.24
, pp. 1817-1825
-
-
Aurisicchio, L.1
Bujard, H.2
Hillen, W.3
-
122
-
-
0030462599
-
A helper-dependent adenovirus vector system: Removal of helper virus by Cre-mediated excision of the viral packaging signal
-
PARKS RJ, CHEN L, ANTON M, SANKAR U, RUDNICKI MA, GRAHAM FL: A helper-dependent adenovirus vector system: removal of helper virus by Cre-mediated excision of the viral packaging signal. Proc. Natl. Acad. Sci. USA (1996) 93(24):13565-13570.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, Issue.24
, pp. 13565-13570
-
-
Parks, R.J.1
Chen, L.2
Anton, M.3
Sankar, U.4
Rudnicki, M.A.5
Graham, F.L.6
-
124
-
-
17344371807
-
Interleukin-10 controls neutrophilic infiltration, hepatocyte proliferation and liver fibrosis induced by carbon tetrachloride in mice
-
LOUIS H, VAN LAETHEM JL, WU W et al.: Interleukin-10 controls neutrophilic infiltration, hepatocyte proliferation and liver fibrosis induced by carbon tetrachloride in mice. Hepatology (1998) 28(6):1607-1615.
-
(1998)
Hepatology
, vol.28
, Issue.6
, pp. 1607-1615
-
-
Louis, H.1
Van Laethem, J.L.2
Wu, W.3
-
125
-
-
0031769880
-
Primary rat and mouse hepatic stellate cells express the macrophage inhibitor cytokine interleukin-10 during the course of activation In vitro
-
THOMPSON KC, TROWERN A, FOWELL A et al.: Primary rat and mouse hepatic stellate cells express the macrophage inhibitor cytokine interleukin-10 during the course of activation In vitro. Hepatalogy (1998) 28(6):1518-1524.
-
(1998)
Hepatalogy
, vol.28
, Issue.6
, pp. 1518-1524
-
-
Thompson, K.C.1
Trowern, A.2
Fowell, A.3
-
126
-
-
0031769883
-
Interleukin-10 expression and function in experimental murine liver inflammation and fibrosis
-
THOMPSON K, MALTBY J, FALLOWFIELD J, MCAULAY M, MILLWARD-SADLER H, SHERON N: Interleukin-10 expression and function in experimental murine liver inflammation and fibrosis. Hepatology (1998) 28(6):1597-1606.
-
(1998)
Hepatology
, vol.28
, Issue.6
, pp. 1597-1606
-
-
Thompson, K.1
Maltby, J.2
Fallowfield, J.3
Mcaulay, M.4
Millward-Sadler, H.5
Sheron, N.6
-
127
-
-
0036199339
-
Intrahepatic cytokine profiles associated with post-transplantation hepatitis C virus-related liver injury
-
ZEKRY A, BISHOP GA, BOWEN DG et al.: Intrahepatic cytokine profiles associated with post-transplantation hepatitis C virus-related liver injury. Liver Transpl. (2002) 8(3):292-301.
-
(2002)
Liver Transpl.
, vol.8
, Issue.3
, pp. 292-301
-
-
Zekry, A.1
Bishop, G.A.2
Bowen, D.G.3
-
128
-
-
0032732659
-
A pilot study of daily subcutaneous interleukin-10 in patients with chronic hepatitis C infection
-
MCHUTCHISON JG, GIANNELLI G, NYBERG L et al.: A pilot study of daily subcutaneous interleukin-10 in patients with chronic hepatitis C infection. J. Interferon Cytokine Res. (1999) 19(11):1265-1270.
-
(1999)
J. Interferon Cytokine Res.
, vol.19
, Issue.11
, pp. 1265-1270
-
-
Mchutchison, J.G.1
Giannelli, G.2
Nyberg, L.3
-
129
-
-
0025735629
-
The dendritic cell system and its role in immunogenicity
-
STEINMAN RM: The dendritic cell system and its role in immunogenicity. Annu. Rev. Immunol. (1991) 9:271-296.
-
(1991)
Annu. Rev. Immunol.
, vol.9
, pp. 271-296
-
-
Steinman, R.M.1
-
130
-
-
0032546352
-
Dendritic cells and the control of immunity
-
(6673)
-
BANCHEREAU J, STEINMAN RM: Dendritic cells and the control of immunity. Nature (1998) 392(6673):245-252.
-
(1998)
Nature
, vol.392
, pp. 245-252
-
-
Banchereau, J.1
Steinman, R.M.2
-
131
-
-
0028285230
-
Proliferating dendritic cell progenitors in human blood
-
ROMANI N, GRUNER S, BRANG D et al.: Proliferating dendritic cell progenitors in human blood. J. Exp. Med. (1994) 180(1):83-93.
-
(1994)
J. Exp. Med.
, vol.180
, Issue.1
, pp. 83-93
-
-
Romani, N.1
Gruner, S.2
Brang, D.3
-
132
-
-
0031941423
-
Vaccination of melanoma patients with peptide- or tumour lysate-pulsed dendritic cells
-
NESTLE FO, ALIJAGIC S, GILLIET M et al.: Vaccination of melanoma patients with peptide- or tumour lysate-pulsed dendritic cells. Nat. Med. (1998) 4(3):328-332.
-
(1998)
Nat. Med.
, vol.4
, Issue.3
, pp. 328-332
-
-
Nestle, F.O.1
Alijagic, S.2
Gilliet, M.3
-
133
-
-
0030820002
-
Dendritic cells transduced with an adenoviral vector encoding a model tumour-associated antigen for tumour vaccination
-
WAN Y, BRAMSON J, CARTER R, GRAHAM F, GAULDIE J: Dendritic cells transduced with an adenoviral vector encoding a model tumour-associated antigen for tumour vaccination. Hum. Gene Ther. (1997) 8(11):1355-1363.
-
(1997)
Hum. Gene Ther.
, vol.8
, Issue.11
, pp. 1355-1363
-
-
Wan, Y.1
Bramson, J.2
Carter, R.3
Graham, F.4
Gauldie, J.5
-
134
-
-
0035210399
-
Preventive antitumour activity against hepatocellular carcinoma (HCC) induced by immunization with fusions of dendritic cells and HCC cells in mice
-
HOMMA S, TODA G, GONG J, KUFE D, OHNO T: Preventive antitumour activity against hepatocellular carcinoma (HCC) induced by immunization with fusions of dendritic cells and HCC cells in mice. J. Gastroenterol (2001) 36(11):764-771.
-
(2001)
J. Gastroenterol.
, vol.36
, Issue.11
, pp. 764-771
-
-
Homma, S.1
Toda, G.2
Gong, J.3
Kufe, D.4
Ohno, T.5
-
135
-
-
0035031066
-
Generation of hepatitis C virus-specific cytotoxic T lymphocytes from healthy individuals with peptide-pulsed dendritic: Cells
-
ITO A, KANTO T, KUZUSHITA N et al.: Generation of hepatitis C virus-specific cytotoxic T lymphocytes from healthy individuals with peptide-pulsed dendritic: cells. J. Gastroenterol. Hepatol. (2001) 16(3):309-316.
-
(2001)
J. Gastroenterol. Hepatol.
, vol.16
, Issue.3
, pp. 309-316
-
-
Ito, A.1
Kanto, T.2
Kuzushita, N.3
-
136
-
-
0037073541
-
Induction of hepatitis C virus-specific cytotoxic T lymphocytes in mice by immunization with dendritic cells transduced with replication-defective recombinant adenovirus
-
MATSUI M, MORIYA O, ABDEL-AZIZ N et al.: Induction of hepatitis C virus-specific cytotoxic T lymphocytes in mice by immunization with dendritic cells transduced with replication-defective recombinant adenovirus. Vaccine (2002) 21(3-4):211-220.
-
(2002)
Vaccine
, vol.21
, Issue.3-4
, pp. 211-220
-
-
Matsui, M.1
Moriya, O.2
Abdel-Aziz, N.3
-
137
-
-
0035121503
-
Impaired allostimulatory function of dendritic cells in chronic hepatitis C infection
-
BAIN C, FATMI A, ZOULIM F et al.: Impaired allostimulatory function of dendritic cells in chronic hepatitis C infection. Gastroenterology (2001) 120(2):512-524.
-
(2001)
Gastroenterology
, vol.120
, Issue.2
, pp. 512-524
-
-
Bain, C.1
Fatmi, A.2
Zoulim, F.3
-
138
-
-
0036237490
-
+ T cells by dendritic cells expressing hepatitis C virus core and E1 proteins
-
+ T cells by dendritic cells expressing hepatitis C virus core and E1 proteins. J. Virol. (2002) 76(10):5062-5070.
-
(2002)
J. Virol.
, vol.76
, Issue.10
, pp. 5062-5070
-
-
Sarobe, P.1
Lasarte, J.J.2
Casares, N.3
-
139
-
-
0032585237
-
Randomised trial of interferon-α-2b plus ribavirin for 48 weeks or for 24 weeks versus interferon-α-2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus
-
International Hepatitis Interventional Therapy Group (IHIT). (9138)
-
POYNARD T, MARCELLIN P, LEE SS et al.: Randomised trial of interferon-α-2b plus ribavirin for 48 weeks or for 24 weeks versus interferon-α-2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus. International Hepatitis Interventional Therapy Group (IHIT). Lancet (1998) 352(9138):1426-1432.
-
(1998)
Lancet
, vol.352
, pp. 1426-1432
-
-
Poynard, T.1
Marcellin, P.2
Lee, S.S.3
-
140
-
-
0032547938
-
Interferon-α-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C
-
Hepatitis Interventional Therapy Group
-
MCHUTCHISON JG, GORDON SC, SCHIFF ER et al.: Interferon-α-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. Hepatitis Interventional Therapy Group. N. Engl. J. Med. (1998) 339(21):1485-1492.
-
(1998)
N. Engl. J. Med.
, vol.339
, Issue.21
, pp. 1485-1492
-
-
Mchutchison, J.G.1
Gordon, S.C.2
Schiff, E.R.3
|