Inhibition of hepatitis C virus NS2/3 processing by NS4A peptides. Implications for control of viral processing

Journal of Biological Chemistry

Volumn 274, Issue 49, 1999, Pages 34511-34514

  Darke, Paul L ^a   Jacobs, Amanda R ^a   Waxman, Lloyd ^a   Kuo, Lawrence C ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS PROTEIN;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; HEPATITIS C VIRUS; NONHUMAN; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION;

AMINO ACID SEQUENCE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; INHIBITORY CONCENTRATION 50; KINETICS; MOLECULAR SEQUENCE DATA; PEPTIDES; VIRAL NONSTRUCTURAL PROTEINS;

EID: 0033521138     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.49.34511     Document Type: Article

References (28)

1. Kuo, G., Choo, Q. L., Alter, H. J., Gitnick, G. L., Redeker, A. G., Purcell, R. H., Miyamura, T., Dienstag, J. L., Alter, M. J., and Stevens, C. E. (1989) Science 244, 362-364
2. Choo, Q.-L., Kuo, G., Weiner, A. J., Overby, L. R., Bradley, D. W., and Houghton, M. (1989) Science 244, 359-362
3. Choo, Q. L., Richman, K. H., Han, J. H., Berger, K., Lee, C., Dong, C., Gallegos, C., Coit, D., Medina-Selby, R., and Barr, P. J. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 2451-2455
4. Grakoui, A., McCourt, D. W., Wychowski, C., Feinstone, S. M., and Rice, C. M. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 10583-10587
5. Selby, M. J., Choo, Q. L., Berger, K., Kuo, G., Glazer, E., Eckart, M., Lee, C., Chien, D., Kuo, C., and Houghton, M. (1993) J. Gen. Virol. 74, 1103-1113
6. Takamizawa, A., Mori, C., Fuke, I., Manabe, S., Murakami, S., Fujita, J., Onishi, E., Andoh, T., Yoshida, I., and Okayama, H. (1991) J. Virol. 65, 1105-1113
7. Neddermann, P., Tomei, L., Steinkuhler, C., Gallinari, P., Tramontano, A., and De Francesco, R. (1997) Biol. Chem. 378, 469-476
8. Lohmann, V., Koch, J. O., and Bartenschlager, R. (1996) J. Hepatol. 24, 11-19
9. Houghton, M., Weiner, A., Han, J., Kuo, G., and Choo, Q. L. (1991) Hepatology 14, 381-388
10. Mizushima, H., Hijikata, M., Tanji, Y., Kimura, K., and Shimotohno, K. (1994) J. Virol. 68, 2731-2734
11. Hijikata, M., Mizushima, H., Tanji, Y., Komoda, Y., Hirowatari, Y., Akagi, T., Kato, N., Kimura, K., and Shimotohno, K. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 10773-10777
12. Komoda, Y., Hijikata, M., Tanji, Y., Hirowatari, Y., Mizushima, H., Kimura, K., and Shimotohno, K. (1994) Gene 145, 221-226
13. Hijikata, M., Mizushima, H., Akagi, T., Mori, S., Kakiuchi, N., Kato, N., Tanaka, T., Kimura, K., and Shimotohno, K. (1993) J. Virol. 67, 4665-4675
14. Santolini, E., Pacini, L., Fipaldini, C., Migliaccio, G., and La Monica, N. (1995) J. Virol. 69, 7461-7471
15. D'Souza, E. D., O'Sullivan, E., Amphlett, E. M., Rowlands, D. J., Sangar, D. V., and Clarke, B. E. (1994) J. Gen. Virol. 75, 3469-3476
16. Pieroni, L., Santolini, E., Fipaldini, C., Pacini, L., Migliaccio, G., and La Monica, N. (1997) J. Virol. 71, 6373-6380
17. Gallinari, P., Brennan, D., Nardi, C., Bruneti, M., Tomei, L., Steinkuhler, C., De Francesco, R. (1998) J. Virol. 72, 6758-6769
18. Wu, Z., Yao, N., Le, H. V., and Weber, P. C. (1998) Trends Biochem. Sci. 23, 92-94
19. Gorbalenya, A. E., and Snijder, E. J. (1996) Perspect. Drug Discov. Des. 6, 64-86
20. Kim, J. L., Morgenstern, K. A., Lin, C., Fox, T., Dwyer, M. D., Landro, J. A., Chambers, S. P., Markland, W., Lepre, C. A., O'Malley, E. T., Harbeson, S. L., Rice, C. M., Murcko, M. A., Caron, P. R., and Thomson, J. A. (1996) Cell 87, 343-355
21. Yan, Y., Li, Y., Munshi, S., Sardana, V., Cole, J. L., Sardana, M., Steinkuhler, C., Tomei, L., De Francesco, R., Kuo, L. C., and Chen, Z. (1998) Protein Sci. 7, 837-847
22. Love, R. A., Parge, H. E., Wickersham, J. A., Hostomsky, Z., Habuka, N., Moomaw, E. W., Adachi, T., and Hostomska, Z. (1996) Cell 87, 331-342
23. Pryor, K. D., and Leiting, B. (1997) Protein Expression Purif. 10, 309-319
24. Bianchi, E., Urbani, A.. Biasiol, G., Brunetti, M., Pessi, A., De Francesco, R., and Steinkuhler, C. (1997) Biochemistry 36, 7890-7897
25. Mizushima, H., Hijikata, M., Asabe, S., Hirota, M., Kimura, K., and Shimotohno, K. (1994) J. Virol. 68, 6215-6222
26. Krausslich, H.-G. (1992) J. Virol. 66, 567-572
27. Reed, K. E., Grakoui, A., and Rice, C. M. (1995) J. Virol. 69, 4127-4136
28. Gallinari, P., Paolini, C., Brennan, D., Nardi, C., Steinkuhler, C., and De Francesco, R. (1999) Biochemistry 38, 5620-5632