Molecular chaperone HSP90 as a novel target for cancer chemotherapy

Folia Pharmacologica Japonica

Volumn 121, Issue 1, 2003, Pages 33-42

  Miyata, Yoshihiko ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Cancer chemotherapy; Geldanamycin; HSP90; Kinase; Signal transduction

Indexed keywords

17 ALLYLAMINOGELDANAMYCIN; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; CELL CYCLE PROTEIN; CHAPERONE; GELDANAMYCIN; HEAT SHOCK PROTEIN 90; PROTEIN KINASE; STEROID RECEPTOR; UNCLASSIFIED DRUG;

APOPTOSIS; CANCER CELL; CANCER CHEMOTHERAPY; CARCINOGENESIS; CELL CYCLE; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CLINICAL TRIAL; CYTOSOL; ENVIRONMENT; HUMAN; NONHUMAN; PHASE 1 CLINICAL TRIAL; PROTEIN CONFORMATION; PROTEIN FOLDING; REVIEW; SIGNAL TRANSDUCTION; STRESS;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BENZOQUINONES; CELL CYCLE PROTEINS; CHAPERONINS; CLINICAL TRIALS, PHASE I; DROSOPHILA PROTEINS; DRUG DESIGN; HSP90 HEAT-SHOCK PROTEINS; HUMANS; LACTAMS, MACROCYCLIC; MOLECULAR CHAPERONES; NEOPLASMS; PROTEIN BINDING; PROTEIN KINASES; QUINONES; RECEPTORS, STEROID; RIFABUTIN; SIGNAL TRANSDUCTION; TACROLIMUS BINDING PROTEINS;

EID: 0037241732     PISSN: 00155691     EISSN: None     Source Type: Journal    
DOI: 10.1254/fpj.121.33     Document Type: Review

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