The human oncoprotein MDM2 arrests the cell cycle: Elimination of its cell-cycle-inhibitory function induces tumorigenesis

EMBO Journal

Volumn 17, Issue 9, 1998, Pages 2513-2525

  Brown, Doris R ^a   Thomas, Charles A ^a   Deb, Swati Palit ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

Cell cycle arrest; Human MDM2; Oncoprotein; Tumorigenesis

Indexed keywords

COMPLEMENTARY DNA; ONCOPROTEIN; PROTEIN P53;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENESIS; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL GROWTH; CELL STRAIN 3T3; CONTROLLED STUDY; DELETION MUTANT; GENE EXPRESSION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN;

3T3 CELLS; ANIMALS; CELL CYCLE; CELL DIVISION; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; FLOW CYTOMETRY; G0 PHASE; G1 PHASE; GENE AMPLIFICATION; HUMANS; MICE; MUTAGENESIS, SITE-DIRECTED; NEOPLASM PROTEINS; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; RECOMBINANT PROTEINS; S PHASE; SEQUENCE DELETION; TRANSFECTION;

ANIMALIA; MURINAE;

EID: 0032080297     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.9.2513     Document Type: Article

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