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Volumn 13, Issue 1, 2003, Pages 31-41

Modulation of cell death in the tumor microenvironment

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ADENOSINE TRIPHOSPHATE; ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; BIOREDUCTIVE DRUG; CARBOGEN; CISPLATIN; GLUCOSE TRANSPORTER; NICOTINAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PRODRUG; RAPAMYCIN; RECOMBINANT ERYTHROPOIETIN; TIRAPAZAMINE; UNCLASSIFIED DRUG; WORTMANNIN;

EID: 0037267568     PISSN: 10534296     EISSN: None     Source Type: Journal    
DOI: 10.1053/srao.2003.50004     Document Type: Review
Times cited : (57)

References (120)
  • 1
    • 84960987950 scopus 로고
    • Concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy
    • Gray LH, Conger AD, Ebert M, et al: Concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy. Br J Radiol 26:638-648, 1953
    • (1953) Br J Radiol , vol.26 , pp. 638-648
    • Gray, L.H.1    Conger, A.D.2    Ebert, M.3
  • 2
    • 0010170555 scopus 로고
    • Hypoxia induces DNA overreplication and enhances metastatic potential of murine tumor cells
    • Young SD, Marshall RS, Hill RP: Hypoxia induces DNA overreplication and enhances metastatic potential of murine tumor cells. Proc Natl Acad Sci U S A 85:9533-9537, 1988
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 9533-9537
    • Young, S.D.1    Marshall, R.S.2    Hill, R.P.3
  • 3
    • 0035805046 scopus 로고    scopus 로고
    • Relationship of hypoxia to metastatic ability in rodent tumours
    • De Jaeger K, Kavanagh MC, Hill RP: Relationship of hypoxia to metastatic ability in rodent tumours. Br J Cancer 84:1280-1285, 2001
    • (2001) Br J Cancer , vol.84 , pp. 1280-1285
    • De Jaeger, K.1    Kavanagh, M.C.2    Hill, R.P.3
  • 4
    • 0030025773 scopus 로고    scopus 로고
    • Hypoxiamediated selection of cells with diminished apoptotic potential in solid tumours
    • Graeber TG, Osmanian C, Jacks T, et al: Hypoxiamediated selection of cells with diminished apoptotic potential in solid tumours. Nature 379:88-91, 1996
    • (1996) Nature , vol.379 , pp. 88-91
    • Graeber, T.G.1    Osmanian, C.2    Jacks, T.3
  • 5
    • 0030864485 scopus 로고    scopus 로고
    • Selection of human cervical epithelial cells that possess reduced apoptotic potential to low-oxygen conditions
    • Kim CY, Tsai MH, Osmanian C, et al: Selection of human cervical epithelial cells that possess reduced apoptotic potential to low-oxygen conditions. Cancer Res 57:4200-4204, 1997
    • (1997) Cancer Res , vol.57 , pp. 4200-4204
    • Kim, C.Y.1    Tsai, M.H.2    Osmanian, C.3
  • 6
    • 0032774194 scopus 로고    scopus 로고
    • Hypoxia-induced metastasis of human melanoma cells: Involvement of vascular endothelial growth factor-mediated angiogenesis
    • Rofstad EK, Danielsen T: Hypoxia-induced metastasis of human melanoma cells: Involvement of vascular endothelial growth factor-mediated angiogenesis. Br J Cancer 80:1697-1707, 1999
    • (1999) Br J Cancer , vol.80 , pp. 1697-1707
    • Rofstad, E.K.1    Danielsen, T.2
  • 7
    • 0031838786 scopus 로고    scopus 로고
    • Response of tumour cells to hypoxia: Role of p 53 and NFkB
    • Royds JA, Dower SK, Qwarnstrom EE, et al: Response of tumour cells to hypoxia: Role of p53 and NFkB. Mol Pathol 51:55-61, 1998
    • (1998) Mol Pathol , vol.51 , pp. 55-61
    • Royds, J.A.1    Dower, S.K.2    Qwarnstrom, E.E.3
  • 8
    • 0034021690 scopus 로고    scopus 로고
    • Hypoxia, clonal selection, and the role of HIF- 1 in tumor progression
    • Semenza GL: Hypoxia, clonal selection, and the role of HIF-1 in tumor progression. Crit Rev Biochem Mol Biol 35:71-103, 2000
    • (2000) Crit Rev Biochem Mol Biol , vol.35 , pp. 71-103
    • Semenza, G.L.1
  • 9
    • 0029775242 scopus 로고    scopus 로고
    • Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix
    • Hockel M, Schlenger K, Aral B, et al: Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res 56:4509-15, 1996
    • (1996) Cancer Res , vol.56 , pp. 4509-4515
    • Hockel, M.1    Schlenger, K.2    Aral, B.3
  • 10
    • 0030742027 scopus 로고    scopus 로고
    • Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck
    • Brizel DM, Sibley GS, Prosnitz LR, et al: Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck. Int J Radiat Oncol Biol Phys 38:285-289, 1997
    • (1997) Int J Radiat Oncol Biol Phys , vol.38 , pp. 285-289
    • Brizel, D.M.1    Sibley, G.S.2    Prosnitz, L.R.3
  • 11
    • 0035917618 scopus 로고    scopus 로고
    • Hypoxia in human soft tissue sarcomas: Adverse impact on survival and no association with p 53 mutations
    • Nordsmark M, Alsner J, Keller J, et al: Hypoxia in human soft tissue sarcomas: Adverse impact on survival and no association with p53 mutations. Br J Cancer 84:1070-1075, 2001
    • (2001) Br J Cancer , vol.84 , pp. 1070-1075
    • Nordsmark, M.1    Alsner, J.2    Keller, J.3
  • 12
    • 0034932899 scopus 로고    scopus 로고
    • Regulation of hypoxia-induced angiogenesis: A chaperone escorts VEGF to the dance
    • Semenza GL: Regulation of hypoxia-induced angiogenesis: A chaperone escorts VEGF to the dance. J Clin Invest 108:39-40, 2001
    • (2001) J Clin Invest , vol.108 , pp. 39-40
    • Semenza, G.L.1
  • 13
    • 0027477360 scopus 로고
    • Oxygenation of head and neck tumors
    • Lartigau E, Le Ridant AM, Lambin P, et al: Oxygenation of head and neck tumors. Cancer 71:2319-2325, 1993
    • (1993) Cancer , vol.71 , pp. 2319-2325
    • Lartigau, E.1    Le Ridant, A.M.2    Lambin, P.3
  • 14
    • 0027265108 scopus 로고
    • Changes in the oxygenation of head and neck tumors during carbogen breathing
    • Martin L, Lartigau E, Weeger P, et al: Changes in the oxygenation of head and neck tumors during carbogen breathing. Radiother Oncol 27:123-130, 1993
    • (1993) Radiother Oncol , vol.27 , pp. 123-130
    • Martin, L.1    Lartigau, E.2    Weeger, P.3
  • 15
    • 0029955072 scopus 로고    scopus 로고
    • Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck
    • Nordsmark M, Overgaard M, Overgaard J: Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck. Radiother Oncol 41:31-39, 1996
    • (1996) Radiother Oncol , vol.41 , pp. 31-39
    • Nordsmark, M.1    Overgaard, M.2    Overgaard, J.3
  • 16
    • 0030476061 scopus 로고    scopus 로고
    • Fluctuations in red cell flux in tumor microvessels can lead to transient hypoxia and reoxygenation in tumor parenchyma
    • Kimura H, Braun RD, Ong ET, et al: Fluctuations in red cell flux in tumor microvessels can lead to transient hypoxia and reoxygenation in tumor parenchyma. Cancer Res 56:5522-5528, 1996
    • (1996) Cancer Res , vol.56 , pp. 5522-5528
    • Kimura, H.1    Braun, R.D.2    Ong, E.T.3
  • 17
    • 0034918106 scopus 로고    scopus 로고
    • In vivo measurement of gene expression, angiogenesis and physiological function in tumors using multiphoton laser scanning microscopy
    • Brown EB, Campbell RB, Tsuzuki Y, et al: In vivo measurement of gene expression, angiogenesis and physiological function in tumors using multiphoton laser scanning microscopy. Nat Med 7:864-868, 2001
    • (2001) Nat Med , vol.7 , pp. 864-868
    • Brown, E.B.1    Campbell, R.B.2    Tsuzuki, Y.3
  • 18
    • 0034037286 scopus 로고    scopus 로고
    • Microenvironment-induced cancer metastasis
    • Rofstad EK: Microenvironment-induced cancer metastasis. Int J Radiat Biol 76:589-605, 2000
    • (2000) Int J Radiat Biol , vol.76 , pp. 589-605
    • Rofstad, E.K.1
  • 19
    • 0032565578 scopus 로고    scopus 로고
    • Mutagenesis induced by the tumor microenvironment
    • Yuan J, Glazer PM: Mutagenesis induced by the tumor microenvironment. Mutat Res 400:439-446, 1998
    • (1998) Mutat Res , vol.400 , pp. 439-446
    • Yuan, J.1    Glazer, P.M.2
  • 20
    • 0034989311 scopus 로고    scopus 로고
    • Biological consequences of tumor hypoxia
    • Hockel M, Vaupel P: Biological consequences of tumor hypoxia. Semin Oncol 28:36-41, 2001
    • (2001) Semin Oncol , vol.28 , pp. 36-41
    • Hockel, M.1    Vaupel, P.2
  • 21
    • 0031940839 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is essential for corpus luteum angiogenesis
    • Ferrara N, Chen H, Davis-Smyth T, et al: Vascular endothelial growth factor is essential for corpus luteum angiogenesis. Nat Med 4:336-340, 1998
    • (1998) Nat Med , vol.4 , pp. 336-340
    • Ferrara, N.1    Chen, H.2    Davis-Smyth, T.3
  • 22
    • 0021239705 scopus 로고
    • Endothelial proliferation in turnouts and normal tissues: Continuous labelling studies
    • Hobson B, Denekamp J: Endothelial proliferation in turnouts and normal tissues: continuous labelling studies. Br J Cancer 49:405-413, 1984
    • (1984) Br J Cancer , vol.49 , pp. 405-413
    • Hobson, B.1    Denekamp, J.2
  • 23
    • 0033233243 scopus 로고    scopus 로고
    • Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1
    • Semenza GL: Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1. Annu Rev Cell Dev Biol 15:551-578, 1999
    • (1999) Annu Rev Cell Dev Biol , vol.15 , pp. 551-578
    • Semenza, G.L.1
  • 24
    • 0034652779 scopus 로고    scopus 로고
    • Candidate genes for the hypoxic tumor phenotype
    • Koong AC, Denko NC, Hudson KM, et al: Candidate genes for the hypoxic tumor phenotype. Cancer Res 60:883-887, 2000
    • (2000) Cancer Res , vol.60 , pp. 883-887
    • Koong, A.C.1    Denko, N.C.2    Hudson, K.M.3
  • 25
    • 0035884701 scopus 로고    scopus 로고
    • HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP 3 and NIX in human tumors
    • Sowter HM, Ratcliffe PJ, Watson P, et al: HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors. Cancer Res 61:6669-6673, 2001
    • (2001) Cancer Res , vol.61 , pp. 6669-6673
    • Sowter, H.M.1    Ratcliffe, P.J.2    Watson, P.3
  • 26
    • 0034255036 scopus 로고    scopus 로고
    • Expression of the gene encoding the proapoptotic Nip 3 protein is induced by hypoxia
    • Bruick RK: Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia. Proc Natl Acad Sci U S A 97:9082-9087, 2000
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 9082-9087
    • Bruick, R.K.1
  • 27
    • 0036463405 scopus 로고    scopus 로고
    • A matter of life and death
    • Green DR, Evan GI: A matter of life and death. Cancer Cell 1:19-30, 2002
    • (2002) Cancer Cell , vol.1 , pp. 19-30
    • Green, D.R.1    Evan, G.I.2
  • 28
    • 0032487926 scopus 로고    scopus 로고
    • Is conversion of solid into more anoxic ascites tumors associated with p53 inactivation?
    • Magnusson KP, Satalino R, Qian W, et al: Is conversion of solid into more anoxic ascites tumors associated with p53 inactivation? Oncogene 17:2333-2337, 1998
    • (1998) Oncogene , vol.17 , pp. 2333-2337
    • Magnusson, K.P.1    Satalino, R.2    Qian, W.3
  • 29
    • 0035255024 scopus 로고    scopus 로고
    • Cancer cells surviving hypoxia obtain hypoxia resistance and maintain anti-apoptotic potential under reoxygenation
    • Kinoshita M, Johnson DL, Shatney CH, et al: Cancer cells surviving hypoxia obtain hypoxia resistance and maintain anti-apoptotic potential under reoxygenation. Int J Cancer 91:322-326, 2001
    • (2001) Int J Cancer , vol.91 , pp. 322-326
    • Kinoshita, M.1    Johnson, D.L.2    Shatney, C.H.3
  • 30
    • 0030056563 scopus 로고    scopus 로고
    • Effects of hypoxia on drug resistance phenotype and genotype in human glioma cell lines
    • Liang BC: Effects of hypoxia on drug resistance phenotype and genotype in human glioma cell lines. J Neurooncol 29:149-155, 1996
    • (1996) J Neurooncol , vol.29 , pp. 149-155
    • Liang, B.C.1
  • 31
    • 0035501326 scopus 로고    scopus 로고
    • Tissue gradients of energy metabolites mirror oxygen tension gradients in a rat mammary carcinoma model
    • Walenta S, Snyder S, Haroon ZA, et al: Tissue gradients of energy metabolites mirror oxygen tension gradients in a rat mammary carcinoma model. Int J Radiat Oncol Biol Phys 51:840-848, 2001
    • (2001) Int J Radiat Oncol Biol Phys , vol.51 , pp. 840-848
    • Walenta, S.1    Snyder, S.2    Haroon, Z.A.3
  • 32
    • 0026756726 scopus 로고
    • Pretranslational regulation of two cardiac glucose transporters in rats exposed to hypobaric hypoxia
    • Sivitz WI, Lund DD, Yorek B, et al: Pretranslational regulation of two cardiac glucose transporters in rats exposed to hypobaric hypoxia. Am J Physiol 263:E562-569, 1992
    • (1992) Am J Physiol , vol.263
    • Sivitz, W.I.1    Lund, D.D.2    Yorek, B.3
  • 33
    • 0028359320 scopus 로고
    • Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: Similarities with the erythropoietin 3′ enhancer
    • Firth JD, Ebert BL, Pugh CW, et al: Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: Similarities with the erythropoietin 3′ enhancer. Proc Natl Acad Sci U S A 91:6496-500, 1994
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 6496-6500
    • Firth, J.D.1    Ebert, B.L.2    Pugh, C.W.3
  • 34
    • 0028068606 scopus 로고
    • Transcriptional regulation of genes encoding glycolytic enzymes by hvpoxia-inducible factor 1
    • Semenza GL, Roth PH, Fang HM, et al: Transcriptional regulation of genes encoding glycolytic enzymes by hvpoxia-inducible factor 1. J Biol Chem 269:23757-23763, 1994
    • (1994) J Biol Chem , vol.269 , pp. 23757-23763
    • Semenza, G.L.1    Roth, P.H.2    Fang, H.M.3
  • 35
    • 0033587146 scopus 로고    scopus 로고
    • The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
    • Maxwell PH, Wiesener MS, Chang GW, et al: The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 399: 271-275, 1999
    • (1999) Nature , vol.399 , pp. 271-275
    • Maxwell, P.H.1    Wiesener, M.S.2    Chang, G.W.3
  • 36
    • 0035917808 scopus 로고    scopus 로고
    • Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regutated prolyl hydroxylation
    • Jaakkola P, Mole DR, Tian YM, et al: Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regutated prolyl hydroxylation. Science 292: 468-472, 2001
    • (2001) Science , vol.292 , pp. 468-472
    • Jaakkola, P.1    Mole, D.R.2    Tian, Y.M.3
  • 37
    • 0035917313 scopus 로고    scopus 로고
    • HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: Implications for O 2 sensing
    • Ivan M, Kondo K, Yang H, et al: HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: Implications for O2 sensing. Science 292:464-468, 2001
    • (2001) Science , vol.292 , pp. 464-468
    • Ivan, M.1    Kondo, K.2    Yang, H.3
  • 38
    • 0037050215 scopus 로고    scopus 로고
    • A protective role for HIF-1 in response to redox manipulation and glucose deprivation: Implications for tumorigenesis
    • Williams KJ, Telfer BA, Airley RE, et al: A protective role for HIF-1 in response to redox manipulation and glucose deprivation: Implications for tumorigenesis. Oncogene 21:282-290, 2002
    • (2002) Oncogene , vol.21 , pp. 282-290
    • Williams, K.J.1    Telfer, B.A.2    Airley, R.E.3
  • 39
    • 0035027828 scopus 로고    scopus 로고
    • Transcription factor HIF- 1 is a necessary mediator of the pasteur effect in mammalian cells
    • Seagroves TN, Ryan HE, Lu H, et al: Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells. Mol Cell Biol 21:3436-3444, 2001
    • (2001) Mol Cell Biol , vol.21 , pp. 3436-3444
    • Seagroves, T.N.1    Ryan, H.E.2    Lu, H.3
  • 40
    • 0037050215 scopus 로고    scopus 로고
    • A protective role for HIF-1 in response to redox manipulation and glucose deprivation: Implications for tumorigenesis
    • Williams KJ, Telfer BA, Airley RE, et al: A protective role for HIF-1 in response to redox manipulation and glucose deprivation: Implications for tumorigenesis. Oncogene 21:282-290, 2002
    • (2002) Oncogene , vol.21 , pp. 282-290
    • Williams, K.J.1    Telfer, B.A.2    Airley, R.E.3
  • 41
    • 0033079597 scopus 로고    scopus 로고
    • Oncogenic alterations of metabolism
    • Dang CV, Semenza GL: Oncogenic alterations of metabolism. Trends Biochem Sci 24:68-72, 1999
    • (1999) Trends Biochem Sci , vol.24 , pp. 68-72
    • Dang, C.V.1    Semenza, G.L.2
  • 42
    • 0022500822 scopus 로고
    • Cellular growth and metabolic adaptations to nutrient stress environments in tumor microregions
    • Sutherland R, Freyer J, Mueller-Klieser W, et al: Cellular growth and metabolic adaptations to nutrient stress environments in tumor microregions. Int J Radiat Oncol Biol Phys 12:611-615, 1986
    • (1986) Int J Radiat Oncol Biol Phys , vol.12 , pp. 611-615
    • Sutherland, R.1    Freyer, J.2    Mueller-Klieser, W.3
  • 43
    • 0020388887 scopus 로고
    • Oxygen effects in radiobiology
    • Koch CJ: Oxygen effects in radiobiology. Adv Exp Med Biol 157:123-144, 1982
    • (1982) Adv Exp Med Biol , vol.157 , pp. 123-144
    • Koch, C.J.1
  • 44
    • 0022500822 scopus 로고
    • Cellular growth and metabolic adaptations to nutrient stress environments in tumor microregions
    • Sutherland R, Freyer J, Mueller-Klieser W, et al: Cellular growth and metabolic adaptations to nutrient stress environments in tumor microregions. Int J Radiat Oncol Biol Phys 12:611-615, 1986
    • (1986) Int J Radiat Oncol Biol Phys , vol.12 , pp. 611-615
    • Sutherland, R.1    Freyer, J.2    Mueller-Klieser, W.3
  • 45
    • 0029796904 scopus 로고    scopus 로고
    • Unifying theory of hypoxia tolerance: Molecular/metabolic defense and rescue mechanisms for surviving oxygen lack
    • Hochachka PW, Buck LT, Doll QJ, et al: Unifying theory of hypoxia tolerance: Molecular/metabolic defense and rescue mechanisms for surviving oxygen lack. Proc Natl Acad Sci U S A 93:9493-9498, 1996
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 9493-9498
    • Hochachka, P.W.1    Buck, L.T.2    Doll, Q.J.3
  • 46
    • 0022450587 scopus 로고
    • Regulation of protein metabolism of human cells during and after acute hypoxia
    • Pettersen EO, Juul NO, Ronning OW: Regulation of protein metabolism of human cells during and after acute hypoxia. Cancer Res 46:4346-4351, 1986
    • (1986) Cancer Res , vol.46 , pp. 4346-4351
    • Pettersen, E.O.1    Juul, N.O.2    Ronning, O.W.3
  • 47
    • 0027297289 scopus 로고
    • Adenine nucleotides and inhibition of protein synthesis in isolated hepatocytes incubated under different pO 2 levels
    • Lefebvre VH, Van Steenbrugge M, Beckers V, et al: Adenine nucleotides and inhibition of protein synthesis in isolated hepatocytes incubated under different pO2 levels. Arch Biochem Biophys 304:322-331, 1993
    • (1993) Arch Biochem Biophys , vol.304 , pp. 322-331
    • Lefebvre, V.H.1    Van Steenbrugge, M.2    Beckers, V.3
  • 48
    • 0000091608 scopus 로고    scopus 로고
    • Pathway and mechanism of initiation of protein synthesis
    • Sonenberg N, Hershey JW, Mathews MB (eds): Cold Spring Harbor, Cols Spring Harbor Laboratory Press
    • Hershey JW, Merrick WC: Pathway and mechanism of initiation of protein synthesis, in Sonenberg N, Hershey JW, Mathews MB (eds): Translational control of gene expression. Cold Spring Harbor, Cols Spring Harbor Laboratory Press, 2000, pp 33-88
    • (2000) Translational Control of Gene Expression , pp. 33-88
    • Hershey, J.W.1    Merrick, W.C.2
  • 49
    • 0036837864 scopus 로고    scopus 로고
    • Regulation of protein synthesis by hypoxia via activation of the protein kinase PERK and phosphorylation of e 1F2atpha
    • Koumenis C, Naczki C, Koritzinsky M, et al: Regulation of protein synthesis by hypoxia via activation of the protein kinase PERK and phosphorylation of e1F2atpha. Mol Cell Biol 22:7405-7416, 2002
    • (2002) Mol Cell Biol , vol.22 , pp. 7405-7416
    • Koumenis, C.1    Naczki, C.2    Koritzinsky, M.3
  • 51
    • 0036173591 scopus 로고    scopus 로고
    • Hypoxia as a target for combined modality treatments
    • Wouters BG, Weppler SA, Koritzinsky M, et al: Hypoxia as a target for combined modality treatments. Eur J Cancer 38:240-257, 2002
    • (2002) Eur J Cancer , vol.38 , pp. 240-257
    • Wouters, B.G.1    Weppler, S.A.2    Koritzinsky, M.3
  • 52
    • 0030069889 scopus 로고    scopus 로고
    • Modification of hypoxia-induced radioresistance in tumors by the use of oxygen and sensitizers
    • Overgaard J, Horsman MR: Modification of hypoxia-induced radioresistance in tumors by the use of oxygen and sensitizers. Semin Radiat Oncol 6:10-21, 1996
    • (1996) Semin Radiat Oncol , vol.6 , pp. 10-21
    • Overgaard, J.1    Horsman, M.R.2
  • 53
    • 0029976702 scopus 로고    scopus 로고
    • Clinical results of hypoxic cell radiosensitisation from hyperbaric oxygen to accelerated radiotherapy, carbogen and nicotinamide
    • Saunders M, Dische S: Clinical results of hypoxic cell radiosensitisation from hyperbaric oxygen to accelerated radiotherapy, carbogen and nicotinamide. Br J Cancer 27:S271-S278, 1996 (Suppl)
    • Br J Cancer , vol.27 , Issue.SUPPL.
    • Saunders, M.1    Dische, S.2
  • 54
    • 0024331256 scopus 로고
    • Sensitization of hypoxic tumour cells - Clinical experience
    • Overgaard J: Sensitization of hypoxic tumour cells - Clinical experience. Int J Radiat Biol 56:801-811, 1989
    • (1989) Int J Radiat Biol , vol.56 , pp. 801-811
    • Overgaard, J.1
  • 55
    • 0028786502 scopus 로고
    • Prognostic value of pretreatment factors in patients with locally advanced carcinoma of the uterine cervix treated by radiotherapy alone
    • Pedersen D, Sogaard H, Overgaard J, et al: Prognostic value of pretreatment factors in patients with locally advanced carcinoma of the uterine cervix treated by radiotherapy alone. Acta Oncol 34:787-795, 1995
    • (1995) Acta Oncol , vol.34 , pp. 787-795
    • Pedersen, D.1    Sogaard, H.2    Overgaard, J.3
  • 56
    • 0024492062 scopus 로고
    • Prognostic value of hemoglobin concentrations and blood transfusions in advanced carcinoma of the cervix treated by radiation therapy: Results of a retrospective study of 386 patients
    • Girinski T, Pejovic-Lenfant MH, Bourhis J, et al: Prognostic value of hemoglobin concentrations and blood transfusions in advanced carcinoma of the cervix treated by radiation therapy: Results of a retrospective study of 386 patients. Int J Radiat Oncol Biol Phys 16:37-42, 1989
    • (1989) Int J Radiat Oncol Biol Phys , vol.16 , pp. 37-42
    • Girinski, T.1    Pejovic-Lenfant, M.H.2    Bourhis, J.3
  • 57
    • 0029163515 scopus 로고
    • Pretreatment hemoglobin level influences local control and survival of TI-T2 squamous cell carcinomas of the glottic larynx
    • Fein DA, Lee WR, Hanlon AL, et al: Pretreatment hemoglobin level influences local control and survival of TI-T2 squamous cell carcinomas of the glottic larynx. J Clin Oncol 13:2077-2083, 1995
    • (1995) J Clin Oncol , vol.13 , pp. 2077-2083
    • Fein, D.A.1    Lee, W.R.2    Hanlon, A.L.3
  • 58
    • 0032425228 scopus 로고    scopus 로고
    • Anemia is associated with decreased survival and increased locoregional failure in patients with locally advanced head and neck carcinoma: A secondary analysis of RTOG 85-27
    • Lee WR, Berkey B, Marcial V, et al: Anemia is associated with decreased survival and increased locoregional failure in patients with locally advanced head and neck carcinoma: A secondary analysis of RTOG 85-27. Int J Radiat Oncol Biol Phys 42:1069-1075, 1998
    • (1998) Int J Radiat Oncol Biol Phys , vol.42 , pp. 1069-1075
    • Lee, W.R.1    Berkey, B.2    Marcial, V.3
  • 59
    • 0026608117 scopus 로고
    • The prognostic value of hemoglobin and a decrease in hemoglobin during radiotherapy in laryngeal carcinoma
    • van Acht MJ, Hermans J, Boks DE, et al: The prognostic value of hemoglobin and a decrease in hemoglobin during radiotherapy in laryngeal carcinoma. Radiother Oncol 23:229-235, 1992
    • (1992) Radiother Oncol , vol.23 , pp. 229-235
    • Van Acht, M.J.1    Hermans, J.2    Boks, D.E.3
  • 60
    • 18144445588 scopus 로고    scopus 로고
    • T1/T2 glottic cancer managed by external beam radiotherapy: The influence of pretreatment hemoglobin on local control
    • Warde P, O'Sullivan B, Bristow RG, et al: T1/T2 glottic cancer managed by external beam radiotherapy: The influence of pretreatment hemoglobin on local control. Int J Radiat Oncol Biol Phys 41:347-353, 1998
    • (1998) Int J Radiat Oncol Biol Phys , vol.41 , pp. 347-353
    • Warde, P.1    O'Sullivan, B.2    Bristow, R.G.3
  • 61
    • 10244250427 scopus 로고    scopus 로고
    • Anemia is associated with lower local-regional control and survival after radiation therapy for head and neck cancer: A prospective study
    • Dubray B, Mosseri V, Brunin F, et al: Anemia is associated with lower local-regional control and survival after radiation therapy for head and neck cancer: a prospective study. Radiology 201:553-558, 1996
    • (1996) Radiology , vol.201 , pp. 553-558
    • Dubray, B.1    Mosseri, V.2    Brunin, F.3
  • 63
    • 0025823382 scopus 로고
    • Results of treatment and lessons learned from pathologically staged T4 non-small cell lung cancer
    • Macchiarini P, Silvano G, Janni A, et al: Results of treatment and lessons learned from pathologically staged T4 non-small cell lung cancer. J Surg Oncol 47:209-214, 1991
    • (1991) J Surg Oncol , vol.47 , pp. 209-214
    • Macchiarini, P.1    Silvano, G.2    Janni, A.3
  • 64
    • 0024412684 scopus 로고
    • The effect of arterial oxygen content on the results of radiation therapy for epidermoid bronchogenic carcinoma
    • Sasai K, Ono K, Hiraoka M, et al: The effect of arterial oxygen content on the results of radiation therapy for epidermoid bronchogenic carcinoma. Int J Radiat Oncol Biol Phys 16:1477-1481, 1989
    • (1989) Int J Radiat Oncol Biol Phys , vol.16 , pp. 1477-1481
    • Sasai, K.1    Ono, K.2    Hiraoka, M.3
  • 65
    • 0029033953 scopus 로고
    • Local control of muscle-invasive bladder cancer: Preoperative radiotherapy and cystectomy versus cystectomy alone
    • Cole CJ, Pollack A, Zagars GK, et al: Local control of muscle-invasive bladder cancer: Preoperative radiotherapy and cystectomy versus cystectomy alone. Int J Radiat Oncol Biol Phys 32:331-340, 1995
    • (1995) Int J Radiat Oncol Biol Phys , vol.32 , pp. 331-340
    • Cole, C.J.1    Pollack, A.2    Zagars, G.K.3
  • 66
    • 0027198729 scopus 로고
    • Blood tests and prognosis in bladder carcinomas treated with definitive radiotherapy
    • Hannisdal E, Fossa SD, Host H: Blood tests and prognosis in bladder carcinomas treated with definitive radiotherapy. Radiother Oncol 27:117-122, 1993
    • (1993) Radiother Oncol , vol.27 , pp. 117-122
    • Hannisdal, E.1    Fossa, S.D.2    Host, H.3
  • 67
    • 0026531489 scopus 로고
    • DNA analysis in predicting survival of irradiated patients with transitional cell carcinoma of bladder
    • Wijkstrom H, Nilsson B, Tribukait B: DNA analysis in predicting survival of irradiated patients with transitional cell carcinoma of bladder. Br J Urol 69:49-55, 1992
    • (1992) Br J Urol , vol.69 , pp. 49-55
    • Wijkstrom, H.1    Nilsson, B.2    Tribukait, B.3
  • 68
    • 0025191431 scopus 로고
    • Prognostic factors in patients with bladder carcinoma treated with definitive irradiation
    • Greven KM, Solin LJ, Hanks GE: Prognostic factors in patients with bladder carcinoma treated with definitive irradiation. Cancer 65:908-912, 1990
    • (1990) Cancer , vol.65 , pp. 908-912
    • Greven, K.M.1    Solin, L.J.2    Hanks, G.E.3
  • 69
    • 0024344648 scopus 로고
    • The influence of initial hemoglobin and blood pressure levels on results of radiation therapy for carcinoma of the prostate
    • Dunphy EP, Petersen IA, Cox RS, et al: The influence of initial hemoglobin and blood pressure levels on results of radiation therapy for carcinoma of the prostate. Int J Radiat Oncol Biol Phys 16:1173-1178, 1989
    • (1989) Int J Radiat Oncol Biol Phys , vol.16 , pp. 1173-1178
    • Dunphy, E.P.1    Petersen, I.A.2    Cox, R.S.3
  • 70
    • 0026734114 scopus 로고
    • Extrapolations from laboratory and preclinical studies for the use ofcarbogen and nicotinamide in radiotherapy
    • Rojas A, Joiner MC, Denekamp J: Extrapolations from laboratory and preclinical studies for the use ofcarbogen and nicotinamide in radiotherapy. Radiother Oncol 24: 123-124, 1992
    • (1992) Radiother Oncol , vol.24 , pp. 123-124
    • Rojas, A.1    Joiner, M.C.2    Denekamp, J.3
  • 71
    • 0025264546 scopus 로고
    • Effect of nicotinamide on the microregional heterogeneity of oxygen delivery within a murine tumor
    • Chaplin DJ, Horsman MR, Trotter MJ: Effect of nicotinamide on the microregional heterogeneity of oxygen delivery within a murine tumor. J Natl Cancer Inst 82:672-676, 1990
    • (1990) J Natl Cancer Inst , vol.82 , pp. 672-676
    • Chaplin, D.J.1    Horsman, M.R.2    Trotter, M.J.3
  • 72
    • 0026008168 scopus 로고
    • Radiosensitization with normobaric oxygen and carbogen
    • Rojas A: Radiosensitization with normobaric oxygen and carbogen. Radiother Oncol 1:65-70, 1991 (Suppl)
    • (1991) Radiother Oncol , vol.1 , Issue.SUPPL. , pp. 65-70
    • Rojas, A.1
  • 73
    • 0028278267 scopus 로고
    • Reducing acute and chronic hypoxia in tumours by combining nicotinamide with carbogen breathing
    • Horsman MR, Nordsmark M, Khalil AA, et al: Reducing acute and chronic hypoxia in tumours by combining nicotinamide with carbogen breathing. Acta Oncol 33: 371-376, 1994
    • (1994) Acta Oncol , vol.33 , pp. 371-376
    • Horsman, M.R.1    Nordsmark, M.2    Khalil, A.A.3
  • 74
    • 0029061380 scopus 로고
    • Carbogen breathing with nicotinamide improves the oxygen status of tumours in patients
    • Laurence VM, Ward R, Dennis IF, et al: Carbogen breathing with nicotinamide improves the oxygen status of tumours in patients. Br J Cancer 72:198-205, 1995
    • (1995) Br J Cancer , vol.72 , pp. 198-205
    • Laurence, V.M.1    Ward, R.2    Dennis, I.F.3
  • 75
    • 0031670159 scopus 로고    scopus 로고
    • Accelerated radiotherapy with carbogen and nicotinamide (ARCON) for laryngeal cancer
    • Kaanders JH, Pop LA, Marres HA, et al: Accelerated radiotherapy with carbogen and nicotinamide (ARCON) for laryngeal cancer. Radiother Oncol 48:115-122, 1998
    • (1998) Radiother Oncol , vol.48 , pp. 115-122
    • Kaanders, J.H.1    Pop, L.A.2    Marres, H.A.3
  • 76
    • 0032756199 scopus 로고    scopus 로고
    • Clinical outcome and tumour microenvironmental effects of accelerated radiotherapy with carbogen and nicotinamide
    • Bussink J, Kaanders JH, Van der Kogel AJ: Clinical outcome and tumour microenvironmental effects of accelerated radiotherapy with carbogen and nicotinamide. Acta Oncol 38:875-882, 1999
    • (1999) Acta Oncol , vol.38 , pp. 875-882
    • Bussink, J.1    Kaanders, J.H.2    Van der Kogel, A.J.3
  • 77
    • 0036498885 scopus 로고    scopus 로고
    • ARCON: Experience in 215 patients with advanced head-and-neck cancer
    • Kaanders JH, Pop LA, Marres HA, et al: ARCON: Experience in 215 patients with advanced head-and-neck cancer. Int J Radiat Oncol Biol Phys 52:769-778, 2002
    • (2002) Int J Radiat Oncol Biol Phys , vol.52 , pp. 769-778
    • Kaanders, J.H.1    Pop, L.A.2    Marres, H.A.3
  • 78
    • 0033214120 scopus 로고    scopus 로고
    • Hypoxic radiosensitizers in radical radiotherapy for patients with bladder carcinoma: Hyperbaric oxygen, misonidazole, and accelerated radiotherapy, carbogen, and nicotinamide
    • Hoskin PJ, Saunders MI, Dische S: Hypoxic radiosensitizers in radical radiotherapy for patients with bladder carcinoma: Hyperbaric oxygen, misonidazole, and accelerated radiotherapy, carbogen, and nicotinamide. Cancer 86:1322-1328, 1999
    • (1999) Cancer , vol.86 , pp. 1322-1328
    • Hoskin, P.J.1    Saunders, M.I.2    Dische, S.3
  • 79
    • 0034194225 scopus 로고    scopus 로고
    • ARCON: Accelerated radiotherapy with carbogen and nicotinamide in head and neck squamous cell carcinomas. The experience of the Co-operative group of radiotherapy of the european organization for research and treatment of cancer (EORTC)
    • Bernier J, Denekamp J, Rojas A, et al: ARCON: Accelerated radiotherapy with carbogen and nicotinamide in head and neck squamous cell carcinomas. The experience of the Co-operative group of radiotherapy of the european organization for research and treatment of cancer (EORTC). Radiother Oncol 55:111-1199, 2000
    • (2000) Radiother Oncol , vol.55 , pp. 111-1199
    • Bernier, J.1    Denekamp, J.2    Rojas, A.3
  • 80
    • 0026417645 scopus 로고
    • Therapeutic advantage of hypoxic cells in tumors: A theoretical study
    • Brown JM, Koong A: Therapeutic advantage of hypoxic cells in tumors: A theoretical study. J Natl Cancer Inst 83:178-185, 1991
    • (1991) J Natl Cancer Inst , vol.83 , pp. 178-185
    • Brown, J.M.1    Koong, A.2
  • 81
    • 0032744732 scopus 로고    scopus 로고
    • Tirapazamine: A new drug producing tumor specific enhancement of platinum-based chemotherapy in non-small-cell lung cancer
    • Wouters BG, Wang LH, Brown JM: Tirapazamine: a new drug producing tumor specific enhancement of platinum-based chemotherapy in non-small-cell lung cancer. Ann Oncol 10:S29-33, 1999
    • (1999) Ann Oncol , vol.10
    • Wouters, B.G.1    Wang, L.H.2    Brown, J.M.3
  • 82
    • 0027288316 scopus 로고
    • SR 4233 (tirapazamine): A new anticancer drug exploiting hypoxia in solid tumours
    • Brown JM: SR 4233 (tirapazamine): A new anticancer drug exploiting hypoxia in solid tumours. Br J Cancer 67:1163-1170, 1993
    • (1993) Br J Cancer , vol.67 , pp. 1163-1170
    • Brown, J.M.1
  • 83
    • 0032144380 scopus 로고    scopus 로고
    • Colonisation of Clostridium in the body is restricted to hypoxic and necrotic areas of tumors
    • Lambin P, Theys J, Landuyt W, et al: Colonisation of Clostridium in the body is restricted to hypoxic and necrotic areas of tumors. Anaerobe 4:183-188, 1998
    • (1998) Anaerobe , vol.4 , pp. 183-188
    • Lambin, P.1    Theys, J.2    Landuyt, W.3
  • 84
    • 0030854392 scopus 로고    scopus 로고
    • Tumor-targeted Salmonella as a novel anticancer vector
    • Pawelek JM, Low KB, Bermudes D: Tumor-targeted Salmonella as a novel anticancer vector. Cancer Res 57:4537-4544, 1997
    • (1997) Cancer Res , vol.57 , pp. 4537-4544
    • Pawelek, J.M.1    Low, K.B.2    Bermudes, D.3
  • 85
    • 0030865697 scopus 로고    scopus 로고
    • Anaerobic bacteria as a gene delivery system that is controlled by the tumor microenvironment
    • Lemmon MJ, van Zijl P, Fox ME, et al: Anaerobic bacteria as a gene delivery system that is controlled by the tumor microenvironment. Gene Ther 4:791-796, 1997
    • (1997) Gene Ther , vol.4 , pp. 791-796
    • Lemmon, M.J.1    Van Zijl, P.2    Fox, M.E.3
  • 86
    • 0035023209 scopus 로고    scopus 로고
    • Specific targeting of cytosine deaminase to solid tumors by engineered Clostridium acetobutylicum
    • Theys J, Landuyt W, Nuyts S, et al: Specific targeting of cytosine deaminase to solid tumors by engineered Clostridium acetobutylicum. Cancer Gene Ther 8:294-297, 2001
    • (2001) Cancer Gene Ther , vol.8 , pp. 294-297
    • Theys, J.1    Landuyt, W.2    Nuyts, S.3
  • 87
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J: Tumor angiogenesis: therapeutic implications. N Engl J Med 285:1182-1186, 1971
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 88
    • 0031856412 scopus 로고    scopus 로고
    • Significance of angiogenesis in cancer therapy
    • McNamara DA, Harmey JH, Walsh TN, et al: Significance of angiogenesis in cancer therapy. Br J Surg 85: 1044-1055, 1998
    • (1998) Br J Surg , vol.85 , pp. 1044-1055
    • McNamara, D.A.1    Harmey, J.H.2    Walsh, T.N.3
  • 89
    • 0026485002 scopus 로고
    • Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
    • Shweiki D, Itin A, Soffer D, Keshet E: Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 359:843-845, 1992
    • (1992) Nature , vol.359 , pp. 843-845
    • Shweiki, D.1    Itin, A.2    Soffer, D.3    Keshet, E.4
  • 90
    • 0029082384 scopus 로고
    • Stabilization of vascular endothelial growth factor mRNA by hypoxia and hypoglycemia and coregulation with other ischemiainduced genes
    • Stein I, Neeman M, Shweiki D, Itin A, et al: Stabilization of vascular endothelial growth factor mRNA by hypoxia and hypoglycemia and coregulation with other ischemiainduced genes. Mol Cell Biol 15:5363-5368, 1995
    • (1995) Mol Cell Biol , vol.15 , pp. 5363-5368
    • Stein, I.1    Neeman, M.2    Shweiki, D.3    Itin, A.4
  • 91
    • 0029761644 scopus 로고    scopus 로고
    • Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
    • Forsythe JA, Jiang BH, Iyer NV, et al: Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol Cell Biol 16:4604-4613, 1996
    • (1996) Mol Cell Biol , vol.16 , pp. 4604-4613
    • Forsythe, J.A.1    Jiang, B.H.2    Iyer, N.V.3
  • 92
    • 0027432324 scopus 로고
    • Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis
    • Plate KH, Breier G, Millauer B, Ullrich A, Risau W: Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis. Cancer Res 53:5822-5827, 1993
    • (1993) Cancer Res , vol.53 , pp. 5822-5827
    • Plate, K.H.1    Breier, G.2    Millauer, B.3    Ullrich, A.4    Risau, W.5
  • 93
    • 0032893263 scopus 로고    scopus 로고
    • SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-l/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types
    • Fong TA, Shawver LK, Sun L, et al: SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-l/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types. Cancer Res 59:99-106, 1999
    • (1999) Cancer Res , vol.59 , pp. 99-106
    • Fong, T.A.1    Shawver, L.K.2    Sun, L.3
  • 94
    • 0033883776 scopus 로고    scopus 로고
    • SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors
    • Laird AD, Vajkoczy P, Shawver LK, et al: SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors. Cancer Res 60:4152-4160, 2000
    • (2000) Cancer Res , vol.60 , pp. 4152-4160
    • Laird, A.D.1    Vajkoczy, P.2    Shawver, L.K.3
  • 95
    • 0034655182 scopus 로고    scopus 로고
    • PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration
    • Wood JM, Bold G, Buchdunger E, et al: PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration. Cancer Res 60:2178-2189, 2000
    • (2000) Cancer Res , vol.60 , pp. 2178-2189
    • Wood, J.M.1    Bold, G.2    Buchdunger, E.3
  • 96
    • 0033692912 scopus 로고    scopus 로고
    • Nuclease-resistant synthetic ribozymes: Developing a new class of therapeutics
    • Usman N, Blatt LM: Nuclease-resistant synthetic ribozymes: developing a new class of therapeutics. J Clin Invest 106:1197-1202, 2000
    • (2000) J Clin Invest , vol.106 , pp. 1197-1202
    • Usman, N.1    Blatt, L.M.2
  • 97
    • 0033822622 scopus 로고    scopus 로고
    • Anti-VEGF anti-body treatment of glioblastoma prolongs survival but results in increased vascular cooption
    • Rubenstein JL, Kim J, Ozawa T, et al: Anti-VEGF anti-body treatment of glioblastoma prolongs survival but results in increased vascular cooption. Neoplasia 2:306-314, 2000
    • (2000) Neoplasia , vol.2 , pp. 306-314
    • Rubenstein, J.L.1    Kim, J.2    Ozawa, T.3
  • 98
    • 0030640962 scopus 로고    scopus 로고
    • Angiostatin: An endogenous inhibitor of angiogenesis and of tumor growth
    • O'Reilly MS: Angiostatin: An endogenous inhibitor of angiogenesis and of tumor growth. Exs 79:273-294, 1997
    • (1997) Exs , vol.79 , pp. 273-294
    • O'Reilly, M.S.1
  • 99
    • 0031454617 scopus 로고    scopus 로고
    • Endostatin: An endogenous inhibitor of angiogenesis and tumor growth
    • O'Reilly MS, Boehm T, Shing Y, et al: Endostatin: An endogenous inhibitor of angiogenesis and tumor growth. Cell 88:277-285, 1997
    • (1997) Cell , vol.88 , pp. 277-285
    • O'Reilly, M.S.1    Boehm, T.2    Shing, Y.3
  • 100
    • 0034783270 scopus 로고    scopus 로고
    • A randomized phase II trial of thalidomide, an angiogenesis inhibitor, in patients with androgen-independent prostate cancer
    • Figg WD, Dahut W, Duray P, et al: A randomized phase II trial of thalidomide, an angiogenesis inhibitor, in patients with androgen-independent prostate cancer. Clin Cancer Res 7:1888-1893, 2001
    • (2001) Clin Cancer Res , vol.7 , pp. 1888-1893
    • Figg, W.D.1    Dahut, W.2    Duray, P.3
  • 101
    • 0031969264 scopus 로고    scopus 로고
    • Angiogenesis and tumor metastasis
    • Zetter BR: Angiogenesis and tumor metastasis. Annu Rev Med 49:407-424, 1998
    • (1998) Annu Rev Med , vol.49 , pp. 407-424
    • Zetter, B.R.1
  • 102
    • 0001453577 scopus 로고    scopus 로고
    • Urokinase receptor antagonists inhibit angiogenesis and primary tumor growth in syngeneic mice
    • Min HY, Doyle LV, Vitt CR, et al: Urokinase receptor antagonists inhibit angiogenesis and primary tumor growth in syngeneic mice. Cancer Res 56:2428-2433, 1996
    • (1996) Cancer Res , vol.56 , pp. 2428-2433
    • Min, H.Y.1    Doyle, L.V.2    Vitt, C.R.3
  • 103
    • 7344262560 scopus 로고    scopus 로고
    • Adenovirus-mediated delivery of a uPA/uPAR antagonist suppresses angiogenesis-dependent tumor growth and dissemination in mice
    • Li H, Lu H, Griscelli F, et al: Adenovirus-mediated delivery of a uPA/uPAR antagonist suppresses angiogenesis-dependent tumor growth and dissemination in mice. Gene Ther 5:1103-1113, 1998
    • (1998) Gene Ther , vol.5 , pp. 1103-1113
    • Li, H.1    Lu, H.2    Griscelli, F.3
  • 104
    • 0033121275 scopus 로고    scopus 로고
    • The role of alphav integrins during angiogenesis: Insights into potential mechanisms of action and clinical development
    • Eliceiri BP, Cheresh DA: The role of alphav integrins during angiogenesis: Insights into potential mechanisms of action and clinical development. J Clin Invest 103: 1227-1230, 1999
    • (1999) J Clin Invest , vol.103 , pp. 1227-1230
    • Eliceiri, B.P.1    Cheresh, D.A.2
  • 105
    • 0036152857 scopus 로고    scopus 로고
    • Enhanced pathological angiogenesis in mice lacking beta 3 integrin or beta3 and beta5 integrins
    • Reynolds LE, Wyder L, Lively JC, et al: Enhanced pathological angiogenesis in mice lacking beta3 integrin or beta3 and beta5 integrins. Nat Med 8:27-34, 2002
    • (2002) Nat Med , vol.8 , pp. 27-34
    • Reynolds, L.E.1    Wyder, L.2    Lively, J.C.3
  • 106
    • 0036156813 scopus 로고    scopus 로고
    • Integrin indecision
    • Carmeliet P: Integrin indecision. Nat Med 8:14-6, 2002
    • (2002) Nat Med , vol.8 , pp. 14-16
    • Carmeliet, P.1
  • 107
    • 0037154738 scopus 로고    scopus 로고
    • Effect of p53 status on tumor response to antiangiogenic therapy
    • Yu JL, Rak JW, Coomber BL, et al: Effect of p53 status on tumor response to antiangiogenic therapy. Science 295:1526-1528, 2002
    • (2002) Science , vol.295 , pp. 1526-1528
    • Yu, J.L.1    Rak, J.W.2    Coomber, B.L.3
  • 108
    • 0035692285 scopus 로고    scopus 로고
    • Possible mechanisms of acquired resistance to anti-angiogenic drugs: Implications for the use of combination therapy approaches
    • Kerbel RS, Yu J, Tran J, et al: Possible mechanisms of acquired resistance to anti-angiogenic drugs: Implications for the use of combination therapy approaches. Cancer Metastasis Rev 20:79-86, 2001
    • (2001) Cancer Metastasis Rev , vol.20 , pp. 79-86
    • Kerbel, R.S.1    Yu, J.2    Tran, J.3
  • 109
    • 0035069527 scopus 로고    scopus 로고
    • Heterogeneous vascular dependence of tumor cell populations
    • Yu JL, Rak JW, Carmeliet P, et al: Heterogeneous vascular dependence of tumor cell populations. Am J Pathol 158:1325-1334, 2001
    • (2001) Am J Pathol , vol.158 , pp. 1325-1334
    • Yu, J.L.1    Rak, J.W.2    Carmeliet, P.3
  • 110
    • 0034050050 scopus 로고    scopus 로고
    • Loss of PTEN facilitates HIF-1-mediated gene expression
    • Zundel W, Schindler C, Haas-Kogan D, et al: Loss of PTEN facilitates HIF-1-mediated gene expression. Genes Dev 14:391-396, 2000
    • (2000) Genes Dev , vol.14 , pp. 391-396
    • Zundel, W.1    Schindler, C.2    Haas-Kogan, D.3
  • 111
    • 0034654174 scopus 로고    scopus 로고
    • Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/ PTEN/AKT/FRAP pathway in human prostate cancer cells: Implications for tumor angiogenesis and therapeutics
    • Zhong H, Chiles K, Feldser D, et al: Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/ PTEN/AKT/FRAP pathway in human prostate cancer cells: Implications for tumor angiogenesis and therapeutics. Cancer Res 60:1541-1545, 2000
    • (2000) Cancer Res , vol.60 , pp. 1541-1545
    • Zhong, H.1    Chiles, K.2    Feldser, D.3
  • 112
    • 0026077284 scopus 로고
    • Antisense inhibition of ras p21 expression that is sensitive to a point mutation
    • Chang EH, Miller PS, Cushman C, et al: Antisense inhibition of ras p21 expression that is sensitive to a point mutation. Biochemistry 30:8283-8286, 1991
    • (1991) Biochemistry , vol.30 , pp. 8283-8286
    • Chang, E.H.1    Miller, P.S.2    Cushman, C.3
  • 113
    • 0029069106 scopus 로고
    • Neoplastic reversion accomplished by high efficiency adenoviral-mediated delivery of an anti-ras ribozyme
    • Feng M, Cabrera G, Deshane J, et al: Neoplastic reversion accomplished by high efficiency adenoviral-mediated delivery of an anti-ras ribozyme. Cancer Res 55: 2024-2028, 1995
    • (1995) Cancer Res , vol.55 , pp. 2024-2028
    • Feng, M.1    Cabrera, G.2    Deshane, J.3
  • 114
    • 0029114769 scopus 로고
    • Intracellular antibodies: Development and therapeutic potential
    • Richardson JH, Marasco WA: Intracellular antibodies: Development and therapeutic potential. Trends Biotechnol 13:306-310, 1995
    • (1995) Trends Biotechnol , vol.13 , pp. 306-310
    • Richardson, J.H.1    Marasco, W.A.2
  • 115
    • 0037149539 scopus 로고    scopus 로고
    • Tumour biology: Herceptin acts as an anti-angiogenic cocktail
    • Izumi Y, Xu L, di Tomaso E, et al: Tumour biology: Herceptin acts as an anti-angiogenic cocktail. Nature 416:279-280, 2002
    • (2002) Nature , vol.416 , pp. 279-280
    • Izumi, Y.1    Xu, L.2    Di Tomaso, E.3
  • 116
    • 0036124415 scopus 로고    scopus 로고
    • Epidermal growth factor receptors as a target for cancer treatment: The emerging role of IMC-C 225 in the treatment of lung and head and neck cancers
    • Herbst RS, Langer QJ: Epidermal growth factor receptors as a target for cancer treatment: The emerging role of IMC-C225 in the treatment of lung and head and neck cancers. Semin Oncol 29:27-36, 2002
    • (2002) Semin Oncol , vol.29 , pp. 27-36
    • Herbst, R.S.1    Langer, Q.J.2
  • 117
    • 0028823416 scopus 로고
    • In vivo gene therapy with p53 or p21 adenovirus for prostate cancer
    • Eastham JA, Hall Sj, Sehgal I, et al: In vivo gene therapy with p53 or p21 adenovirus for prostate cancer. Cancer Res 55:5151-5155, 1995
    • (1995) Cancer Res , vol.55 , pp. 5151-5155
    • Eastham, J.A.1    Hall, S.J.2    Sehgal, I.3
  • 118
    • 9544244796 scopus 로고    scopus 로고
    • Retrovirusmediated wild-type p53 gene transfer to tumors of patients with lung cancer
    • Roth JA, Nguyen D, Lawrence DD, et al: Retrovirusmediated wild-type p53 gene transfer to tumors of patients with lung cancer. Nat Med 2:985-991, 1996
    • (1996) Nat Med , vol.2 , pp. 985-991
    • Roth, J.A.1    Nguyen, D.2    Lawrence, D.D.3
  • 119
    • 0035122485 scopus 로고    scopus 로고
    • Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR-ABL tyrosine kinase
    • Vigneri P, Wang JY: Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR-ABL tyrosine kinase. Nat Med 7:228-234, 2001
    • (2001) Nat Med , vol.7 , pp. 228-234
    • Vigneri, P.1    Wang, J.Y.2
  • 120
    • 0033551066 scopus 로고    scopus 로고
    • Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists
    • Chen YN, Sharma SK, Ramsey TM, et al: Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists. Proc Natl Acad Sci U S A 96:4325-4329, 1999
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 4325-4329
    • Chen, Y.N.1    Sharma, S.K.2    Ramsey, T.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.